Works by BHARTI, KAPIL

Results: 39

Perspectives on the cost of goods for hPSC banks for manufacture of cell therapies.

Published in:

NPJ Regenerative Medicine, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41536-022-00242-7

By:

Kim, Jung-Hyun;
Kawase, Eihachiro;
Bharti, Kapil;
Karnieli, Ohad;
Arakawa, Yuji;
Stacey, Glyn

Publication type:

Article

iPSC-derived retinal pigment epithelium: an in vitro platform to reproduce key cellular phenotypes and pathophysiology of retinal degenerative diseases.

Published in:

Stem Cells Translational Medicine, 2025, v. 14, n. 3, p. 1, doi. 10.1093/stcltm/szae097

By:

Li, Huirong;
Sharma, Ruchi;
Bharti, Kapil

Publication type:

Article

Progress in Stem Cells-Based Replacement Therapy for Retinal Pigment Epithelium: In Vitro Differentiation to In Vivo Delivery.

Published in:

Stem Cells Translational Medicine, 2023, v. 12, n. 8, p. 536, doi. 10.1093/stcltm/szad039

By:

Gupta, Santosh;
Lytvynchuk, Lyubomyr;
Ardan, Taras;
Studenovska, Hana;
Sharma, Ruchi;
Faura, Georgina;
Eide, Lars;
Shanker Verma, Rama;
Znaor, Ljubo;
Erceg, Slaven;
Stieger, Knut;
Motlik, Jan;
Petrovski, Goran;
Bharti, Kapil

Publication type:

Article

Regulatory considerations for developing a phase I investigational new drug application for autologous induced pluripotent stem cells‐based therapy product.

Published in:

Stem Cells Translational Medicine, 2021, v. 10, n. 2, p. 198, doi. 10.1002/sctm.20-0242

By:

Jha, Balendu Shekhar;
Farnoodian, Mitra;
Bharti, Kapil

Publication type:

Article

In Pursuit of Authenticity: Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Clinical Applications.

Published in:

Stem Cells Translational Medicine, 2016, v. 5, n. 11, p. 1562, doi. 10.5966/sctm.2016-0037

By:

Miyagishima, Kiyoharu J.;
Wan, Qin;
Corneo, Barbara;
Sharma, Ruchi;
Lotfi, Mostafa R.;
Boles, Nathan C.;
Hua, Fang;
Maminishkis, Arvydas;
Zhang, Congxiao;
Blenkinsop, Timothy;
Khristov, Vladimir;
Jha, Balendu S.;
Memon, Omar S.;
D’Souza, Sunita;
Temple, Sally;
Miller, Sheldon S.;
Bharti, Kapil

Publication type:

Article

A Multiplex High-Throughput Gene Expression Assay to Simultaneously Detect Disease and Functional Markers in Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium.

Published in:

Stem Cells Translational Medicine, 2014, v. 3, n. 8, p. 911, doi. 10.5966/sctm.2013-0192

By:

FERRER, MARC;
CORNEO, BARBARA;
DAVIS, JANINE;
WAN, QIN;
MIYAGISHIMA, KIYOHARU JOSHUA;
KING, REBECCA;
MAMINISHKIS, ARVYDAS;
MARUGAN, JUAN;
SHARMA, RUCHI;
SHURE, MICHAEL;
TEMPLE, SALLY;
MILLER, SHELDON;
BHARTI, KAPIL

Publication type:

Article

Efficient and Rapid Derivation of Primitive Neural Stem Cells and Generation of Brain Subtype Neurons From Human Pluripotent Stem Cells.

Published in:

Stem Cells Translational Medicine, 2013, v. 2, n. 12, p. 960, doi. 10.5966/sctm.2013-0080

By:

YIPING YAN;
SOOJUNG SHIN;
BALENDU SHEKHAR JHA;
QIUYUE LIU;
JIANTING SHENG;
FUHAI LI;
MING ZHAN;
JANINE DAVIS;
KAPIL BHARTI;
XIANMIN ZENG;
MAHENDRA RAO;
NASIR MALIK;
VEMURI, MOHAN C.

Publication type:

Article

Erratum.

Published in:

Stem Cells Translational Medicine, 2013, v. 2, n. 11, p. 870, doi. 10.5966/sctm.2013-0080

By:

YIPING YAN;
SOOJUNG SHIN;
BALENDU SHEKHAR JHA;
QIUYUE LIU;
JIANTING SHENG;
FUHAI LI;
MING ZHAN;
JANINE DAVIS;
KAPIL BHARTI;
XIANMIN ZENG;
MAHENDRA RAO;
NASIR MALIK;
VEMURI, MOHAN C.

Publication type:

Article

Efficient and Rapid Derivation of Primitive Neural Stem Cells and Generation of Brain Subtype Neurons From Human Pluripotent Stem Cells.

Published in:

Stem Cells Translational Medicine, 2013, v. 2, n. 11, p. 862, doi. 10.5966/sctm.2013-0080

By:

YIPING YAN;
SOOJUNG SHIN;
JHA, BALENDU SHEKHAR;
QIUYUE LIU;
JIANTING SHENG;
FUHAI LI;
MING ZHAN;
DAVIS, JANINE;
BHARTI, KAPIL;
XIANMIN ZENG;
RAO, MAHENDRA;
MALIK, NASIR;
VEMURI, MOHAN C.

Publication type:

Article

The new paradigm: retinal pigment epithelium cells generated from embryonic or induced pluripotent stem cells.

Published in:

Pigment Cell & Melanoma Research, 2011, v. 24, n. 1, p. 21, doi. 10.1111/j.1755-148X.2010.00772.x

By:

Bharti, Kapil;
Miller, Sheldon S.;
Arnheiter, Heinz

Publication type:

Article

Ribosomes and p53 – a new KIT for skin darkening.

Published in:

Pigment Cell & Melanoma Research, 2008, v. 21, n. 5, p. 501, doi. 10.1111/j.1755-148X.2008.00488.x

By:

Arnheiter, Heinz;
Bharti, Kapil

Publication type:

Article

A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model.

Published in:

PLoS ONE, 2022, v. 17, n. 1, p. 1, doi. 10.1371/journal.pone.0261821

By:

Dorjsuren, Dorjbal;
Eastman, Richard T.;
Song, Min Jae;
Yasgar, Adam;
Chen, Yuchi;
Bharti, Kapil;
Zakharov, Alexey V.;
Jadhav, Ajit;
Ferrer, Marc;
Shi, Pei-Yong;
Simeonov, Anton

Publication type:

Article

Retinal Pigment Epithelium Cell Development: Extrapolating Basic Biology to Stem Cell Research.

Published in:

Biomedicines, 2023, v. 11, n. 2, p. 310, doi. 10.3390/biomedicines11020310

By:

Gupta, Santosh;
Lytvynchuk, Lyubomyr;
Ardan, Taras;
Studenovska, Hana;
Faura, Georgina;
Eide, Lars;
Znaor, Ljubo;
Erceg, Slaven;
Stieger, Knut;
Motlik, Jan;
Bharti, Kapil;
Petrovski, Goran

Publication type:

Article

Long-Term Transplant Effects of iPSC-RPE Monolayer in Immunodeficient RCS Rats.

Published in:

Cells (2073-4409), 2021, v. 10, n. 11, p. 2951, doi. 10.3390/cells10112951

By:

Rajendran Nair, Deepthi S.;
Zhu, Danhong;
Sharma, Ruchi;
Martinez Camarillo, Juan Carlos;
Bharti, Kapil;
Hinton, David R.;
Humayun, Mark S.;
Thomas, Biju B.

Publication type:

Article

Stem cell sources and characterization in the development of cell-based products for treating retinal disease: An NEI Town Hall report.

Published in:

Stem Cell Research & Therapy, 2023, v. 14, n. 1, p. 1, doi. 10.1186/s13287-023-03282-y

By:

Fortress, Ashley M.;
Miyagishima, Kiyoharu J.;
Reed, Amberlynn A.;
Temple, Sally;
Clegg, Dennis O.;
Tucker, Budd A.;
Blenkinsop, Timothy A.;
Harb, George;
Greenwell, Thomas N.;
Ludwig, Tenneille E.;
Bharti, Kapil

Publication type:

Article

Developing autologous cell therapy for macular degeneration: From bench‐to‐bedside.

Published in:

2022

By:

Bharti, Kapil;
Investigator, Senior

Publication type:

Abstract

PAX6 Regulates Melanogenesis in the Retinal Pigmented Epithelium through Feed-Forward Regulatory Interactions with MITF.

Published in:

PLoS Genetics, 2014, v. 10, n. 5, p. 1, doi. 10.1371/journal.pgen.1004360

By:

Raviv, Shaul;
Bharti, Kapil;
Rencus-Lazar, Sigal;
Cohen-Tayar, Yamit;
Schyr, Rachel;
Evantal, Naveh;
Meshorer, Eran;
Zilberberg, Alona;
Idelson, Maria;
Reubinoff, Benjamin;
Grebe, Rhonda;
Rosin-Arbesfeld, Rina;
Lauderdale, James;
Lutty, Gerard;
Arnheiter, Heinz;
Ashery-Padan, Ruth

Publication type:

Article

A Regulatory Loop Involving PAX6, MITF, and WNT Signaling Controls Retinal Pigment Epithelium Development.

Published in:

PLoS Genetics, 2012, v. 8, n. 7, p. 1, doi. 10.1371/journal.pgen.1002757

By:

Bharti, Kapil;
Gasper, Melanie;
Jingxing Ou;
Brucato, Martha;
Clore-Gronenborn, Katharina;
Pickel, James;
Arnheiter, Heinz

Publication type:

Article

Deep learning predicts function of live retinal pigment epithelium from quantitative microscopy.

Published in:

2020

By:

Schaub, Nicholas J.;
Hotaling, Nathan A.;
Manescu, Petre;
Padi, Sarala;
Wan, Qin;
Sharma, Ruchi;
George, Aman;
Chalfoun, Joe;
Simon, Mylene;
Ouladi, Mohamed;
Simon Jr., Carl G.;
Bajcsy, Peter;
Bharti, Kapil;
Simon, Carl G Jr

Publication type:

journal article

VEGF regulates local inhibitory complement proteins in the eye and kidney.

Published in:

2017

By:

Keir, Lindsay S.;
Firth, Rachel;
Aponik, Lyndsey;
Feitelberg, Daniel;
Susumu Sakimoto;
Aguilar, Edith;
Welsh, Gavin I.;
Richards, Anna;
Yoshihiko Usui;
Satchell, Simon C.;
Kuzmuk, Valeryia;
Coward, Richard J.;
Goult, Jonathan;
Bull, Katherine R.;
Sharma, Ruchi;
Bharti, Kapil;
Westenskow, Peter D.;
Michael, lacovos P.;
Saleem, Moin A.;
Friedlander, Martin

Publication type:

journal article

Lah Number Mediated Analytical Two‐center Two‐electron Integrals of Coulomb Green Function of H‐like Orbitals for 1Σ States.

Published in:

ChemistrySelect, 2023, v. 8, n. 45, p. 1, doi. 10.1002/slct.202205018

By:

Kapil, Bharti;
Sharma, Shivalika;
Aggarwal, Priyanka;
Hazra, Ram Kuntal

Publication type:

Article

Training to Improve Precision and Accuracy in the Measurement of Fiber Morphology.

Published in:

PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0167664

By:

Hotaling, Nathan A.;
Jeon, Jun;
Wade, Mary Beth;
Luong, Derek;
Palmer, Xavier-Lewis;
Bharti, Kapil;
JrSimon, Carl G.

Publication type:

Article

Sodium-Iodate Injection Can Replicate Retinal Degenerative Disease Stages in Pigmented Mice and Rats: Non-Invasive Follow-Up Using OCT and ERG.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 6, p. 2918, doi. 10.3390/ijms23062918

By:

Koster, Céline;
van den Hurk, Koen T.;
ten Brink, Jacoline B.;
Lewallen, Colby F.;
Stanzel, Boris V.;
Bharti, Kapil;
Bergen, Arthur A.

Publication type:

Article

Isolation and characterization of HsfA3, a new heat stress transcription factor of Lycopersicon peruvianum.

Published in:

Plant Journal, 2000, v. 22, n. 4, p. 355, doi. 10.1046/j.1365-313x.2000.00746.x

By:

Bharti, Kapil;
Schmidt, Enrico;
Lyck, Ruth;
Heerklotz, Dirk;
Bublak, Daniela;
Scharf, Klaus-Dieter

Publication type:

Article

The Indirect Role of Fibroblast Growth Factor-8 in Defining Neurogenic Niches of the Olfactory/GnRH Systems.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 50, p. 19620, doi. 10.1523/JNEUROSCI.3238-13.2013

By:

Forni, Paolo Emanuele;
Bharti, Kapil;
Flannery, Ellen M.;
Shimogori, Tomomi;
Wray, Susan

Publication type:

Article

Analytical two-center one-electron overlap and exchange integrals for 1Σ states: Lah number guided Coulomb Green function of <bold>H</bold>-like <bold>s</bold>-orbitals.

Published in:

Journal of Chemical Sciences, 2023, v. 135, n. 2, p. 1, doi. 10.1007/s12039-023-02153-6

By:

Kapil, Bharti;
Hazra, Ram Kuntal

Publication type:

Article

When Pigment Cells Turn Into Neurons.

Published in:

Journal of Investigative Dermatology, 2005, v. 125, n. 4, p. x, doi. 10.1111/j.0022-202X.2005.23876.x

By:

Bharti, Kapil;
Arnheiter, Heinz

Publication type:

Article

Src-Dependent Phosphorylation of ASAP1 Regulates Podosomes.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 23, p. 20, doi. 10.1128/MCB.01781-06

By:

Bharti, Sanita;
Inoue, Hiroki;
Bharti, Kapil;
Hirsch, Dianne S.;
Zhongzhen Nie;
Hye-Young Yoon;
Artym, Vira;
Yamada, Kenneth M.;
Mueller, Susette C.;
Barr, Valarie A.;
Randazzo, Paul A.

Publication type:

Article

The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1527018

By:

Armento, Angela;
Sonntag, Inga;
Almansa-Garcia, Ana-Cristina;
Sen, Merve;
Bolz, Sylvia;
Arango-Gonzalez, Blanca;
Kilger, Ellen;
Sharma, Ruchi;
Bharti, Kapil;
Fernandez-Godino, Rosario;
de la Cerda, Berta;
Clark, Simon J.;
Ueffing, Marius

Publication type:

Article

Generation of an inducible RPE-specific Cre transgenic-mouse line.

Published in:

PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0207222

By:

Schneider, Sandra;
Hotaling, Nathan;
Campos, Maria;
Patnaik, Sarita Rani;
Bharti, Kapil;
May-Simera, Helen Louise

Publication type:

Article

Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration.

Published in:

PLoS Biology, 2023, v. 21, n. 12, p. 1, doi. 10.1371/journal.pbio.3002402

By:

Kretschmer, Viola;
Schneider, Sandra;
Matthiessen, Peter Andreas;
Reichert, Dominik;
Hotaling, Nathan;
Glasßer, Gunnar;
Lieberwirth, Ingo;
Bharti, Kapil;
De Cegli, Rossella;
Conte, Ivan;
Nandrot, Emeline F.;
May-Simera, Helen Louise

Publication type:

Article

Stem cell-derived co-grafts contribute to retinal reconstruction and visual functional improvement in a laser damaged rat model.

Published in:

Military Medical Research, 2025, v. 12, n. 1, p. 1, doi. 10.1186/s40779-025-00601-7

By:

Rajendran Nair, Deepthi S.;
Seiler, Magdalene J.;
Martinez-Camarillo, Juan Carlos;
Xue, Yuntian;
Sharma, Ruchi;
Bharti, Kapil;
Humayun, Mark S.;
Thomas, Biju B.

Publication type:

Article

Vax1/2 Genes Counteract Mitf-Induced Respecification of the Retinal Pigment Epithelium.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059247

By:

Ou, Jingxing;
Bharti, Kapil;
Nodari, Alessandro;
Bertuzzi, Stefano;
Arnheiter, Heinz

Publication type:

Article

Nanofiber Scaffold-Based Tissue-Engineered Retinal Pigment Epithelium to Treat Degenerative Eye Diseases.

Published in:

2016

By:

Hotaling, Nathan A.;
Khristov, Vladimir;
Qin Wan;
Sharma, Ruchi;
Jha, Balendu Shekhar;
Lotfi, Mostafa;
Maminishkis, Arvydas;
Simon Jr., Carl G.;
Bharti, Kapil;
Wan, Qin;
Simon, Carl G Jr

Publication type:

journal article

The Homeodomain Transcription Factors Vax1 and Six6 Are Required for SCN Development and Function.

Published in:

Molecular Neurobiology, 2020, v. 57, n. 2, p. 1217, doi. 10.1007/s12035-019-01781-9

By:

Pandolfi, Erica C.;
Breuer, Joseph A.;
Nguyen Huu, Viet Anh;
Talluri, Tulasi;
Nguyen, Duong;
Lee, Jessica Sora;
Hu, Rachael;
Bharti, Kapil;
Skowronska-Krawczyk, Dorota;
Gorman, Michael R.;
Mellon, Pamela L.;
Hoffmann, Hanne M.

Publication type:

Article

MITF – A controls branching morphogenesis and nephron endowment.

Published in:

PLoS Genetics, 2017, v. 13, n. 12, p. 1, doi. 10.1371/journal.pgen.1007093

By:

Phelep, Aurélie;
Laouari, Denise;
Bharti, Kapil;
Burtin, Martine;
Tammaccaro, Salvina;
Garbay, Serge;
Nguyen, Clément;
Vasseur, Florence;
Blanc, Thomas;
Berissi, Sophie;
Langa-Vives, Francina;
Fischer, Evelyne;
Druilhe, Anne;
Arnheiter, Heinz;
Friedlander, Gerard;
Pontoglio, Marco;
Terzi, Fabiola

Publication type:

Article

Analytical multiconfiguration treatment to one-center many-electron He-isoelectronic ions and Period-II elements with H-like bound-states.

Published in:

Theoretical Chemistry Accounts: Theory, Computation, & Modeling, 2023, v. 142, n. 10, p. 1, doi. 10.1007/s00214-023-03011-x

By:

Kapil, Bharti;
Sharma, Shivalika;
Aggarwal, Priyanka;
Hazra, Ram Kuntal

Publication type:

Article

Identifying core biological processes distinguishing human eye tissues with precise systems-level gene expression analyses and weighted correlation networks.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 19, p. 3325, doi. 10.1093/hmg/ddy239

By:

Bryan, John M;
Fufa, Temesgen D;
Bharti, Kapil;
Brooks, Brian P;
Hufnagel, Robert B;
McGaughey, David M

Publication type:

Article

Patching the retina with stem cells.

Published in:

Nature Biotechnology, 2018, v. 36, n. 4, p. 311, doi. 10.1038/nbt.4118

By:

Bharti, Kapil

Publication type:

Article

Works by BHARTI, KAPIL

Perspectives on the cost of goods for hPSC banks for manufacture of cell therapies.

iPSC-derived retinal pigment epithelium: an in vitro platform to reproduce key cellular phenotypes and pathophysiology of retinal degenerative diseases.

Progress in Stem Cells-Based Replacement Therapy for Retinal Pigment Epithelium: In Vitro Differentiation to In Vivo Delivery.

Regulatory considerations for developing a phase I investigational new drug application for autologous induced pluripotent stem cells‐based therapy product.

In Pursuit of Authenticity: Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Clinical Applications.

A Multiplex High-Throughput Gene Expression Assay to Simultaneously Detect Disease and Functional Markers in Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium.

Efficient and Rapid Derivation of Primitive Neural Stem Cells and Generation of Brain Subtype Neurons From Human Pluripotent Stem Cells.

Erratum.

Efficient and Rapid Derivation of Primitive Neural Stem Cells and Generation of Brain Subtype Neurons From Human Pluripotent Stem Cells.

The new paradigm: retinal pigment epithelium cells generated from embryonic or induced pluripotent stem cells.

Ribosomes and p53 – a new KIT for skin darkening.

A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model.

Retinal Pigment Epithelium Cell Development: Extrapolating Basic Biology to Stem Cell Research.

Long-Term Transplant Effects of iPSC-RPE Monolayer in Immunodeficient RCS Rats.

Stem cell sources and characterization in the development of cell-based products for treating retinal disease: An NEI Town Hall report.

Developing autologous cell therapy for macular degeneration: From bench‐to‐bedside.

PAX6 Regulates Melanogenesis in the Retinal Pigmented Epithelium through Feed-Forward Regulatory Interactions with MITF.

A Regulatory Loop Involving PAX6, MITF, and WNT Signaling Controls Retinal Pigment Epithelium Development.

Deep learning predicts function of live retinal pigment epithelium from quantitative microscopy.

VEGF regulates local inhibitory complement proteins in the eye and kidney.

Lah Number Mediated Analytical Two‐center Two‐electron Integrals of Coulomb Green Function of H‐like Orbitals for <sup>1</sup>Σ States.

Training to Improve Precision and Accuracy in the Measurement of Fiber Morphology.

Sodium-Iodate Injection Can Replicate Retinal Degenerative Disease Stages in Pigmented Mice and Rats: Non-Invasive Follow-Up Using OCT and ERG.

Isolation and characterization of HsfA3, a new heat stress transcription factor of Lycopersicon peruvianum.

The Indirect Role of Fibroblast Growth Factor-8 in Defining Neurogenic Niches of the Olfactory/GnRH Systems.

Analytical two-center one-electron overlap and exchange integrals for 1Σ states: Lah number guided Coulomb Green function of <bold>H</bold>-like <bold>s</bold>-orbitals.

When Pigment Cells Turn Into Neurons.

Src-Dependent Phosphorylation of ASAP1 Regulates Podosomes.

The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells.

Generation of an inducible RPE-specific Cre transgenic-mouse line.

Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration.

Stem cell-derived co-grafts contribute to retinal reconstruction and visual functional improvement in a laser damaged rat model.

<i>Vax1/2</i> Genes Counteract <i>Mitf</i>-Induced Respecification of the Retinal Pigment Epithelium.

Nanofiber Scaffold-Based Tissue-Engineered Retinal Pigment Epithelium to Treat Degenerative Eye Diseases.

The Homeodomain Transcription Factors Vax1 and Six6 Are Required for SCN Development and Function.

MITF – A controls branching morphogenesis and nephron endowment.

Analytical multiconfiguration treatment to one-center many-electron He-isoelectronic ions and Period-II elements with H-like bound-states.

Identifying core biological processes distinguishing human eye tissues with precise systems-level gene expression analyses and weighted correlation networks.

Patching the retina with stem cells.