Works by BELARDINELLI, LUIZ
Results: 79
Na<sup>+</sup> channel function, regulation, structure, trafficking and sequestration.
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- Journal of Physiology, 2015, v. 593, n. 6, p. 1347, doi. 10.1113/jphysiol.2014.281428
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- Article
A computational modelling approach combined with cellular electrophysiology data provides insights into the therapeutic benefit of targeting the late Na<sup>+</sup> current.
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- Journal of Physiology, 2015, v. 593, n. 6, p. 1429, doi. 10.1113/jphysiol.2014.279554
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- Article
Deranged sodium to sudden death.
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- Journal of Physiology, 2015, v. 593, n. 6, p. 1331, doi. 10.1113/jphysiol.2014.281204
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- Article
CrossTalk proposal: The late sodium current is an important player in the development of diastolic heart failure (heart failure with a preserved ejection fraction).
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- Journal of Physiology, 2014, v. 592, n. 3, p. 411, doi. 10.1113/jphysiol.2013.262261
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- Article
Rebuttal from Marc Pourrier, Sarah Williams, Donald McAfee, Luiz Belardinelli and David Fedida.
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- Journal of Physiology, 2014, v. 592, n. 3, p. 419, doi. 10.1113/jphysiol.2013.268896
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- Article
A population pharmacokinetic/pharmacodynamic analysis of regadenoson, an adenosine A2A-receptor agonist, in healthy male volunteers.
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- 2006
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- Publication type:
- journal article
Late sodium current contributes to diastolic cell Ca<sup>2+</sup> accumulation in chronic heart failure.
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- Journal of Physiological Sciences, 2010, v. 60, n. 4, p. 245, doi. 10.1007/s12576-010-0092-0
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- Article
Coronary microcirculatory vasoconstriction induced by low-flow ischemia in mouse hearts is reversed by an A2A adenosine receptor agonist.
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- FASEB Journal, 2007, v. 21, n. 6, p. A1227
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- Article
Effect of Ranolazine Monotherapy on Glycemic Control in Subjects With Type 2 Diabetes.
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- Diabetes Care, 2015, v. 38, n. 7, p. 1189, doi. 10.2337/dc14-2629
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- Article
Effect of Ranolazine on A1C and Glucose Levels in Hyperglycemic Patients With Non-ST Elevation Acute Coronary Syndrome.
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- Diabetes Care, 2010, v. 33, n. 6, p. 1163, doi. 10.2337/dc09-2334
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- Publication type:
- Article
Basal late sodium current is a significant contributor to the duration of action potential of guinea pig ventricular myocytes.
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- Physiological Reports, 2017, v. 5, n. 10, p. n/a, doi. 10.14814/phy2.13295
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- Article
Carbon monoxide effects on human ventricle action potential assessed by mathematical simulations.
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- Frontiers in Physiology, 2013, v. 4, p. 1, doi. 10.3389/fphys.2013.00282
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- Article
Anti-arrhythmic potential of the late sodium current inhibitor GS-458967 inmurine Scn5a-1798insD<sup>+/-</sup> and human SCN5A-1795insD<sup>+/-</sup> iPSC-derived cardiomyocytes.
- Published in:
- Cardiovascular Research, 2017, v. 113, n. 7, p. 829, doi. 10.1093/cvr/cvx077
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- Article
Late I<sub>Na</sub> increases diastolic SR-Ca<sup>2+</sup>-leak in atrial myocardium by activating PKA and CaMKII.
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- Cardiovascular Research, 2015, v. 107, n. 1, p. 184, doi. 10.1093/cvr/cvv153
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- Article
The arrhythmogenic consequences of increasing late INa in the cardiomyocyte.
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- Cardiovascular Research, 2013, v. 99, n. 4, p. 600, doi. 10.1093/cvr/cvt145
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- Article
Adenosine A2B Receptor and Hyaluronan Modulate Pulmonary Hypertension Associated with Chronic Obstructive Pulmonary Disease.
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- American Journal of Respiratory Cell & Molecular Biology, 2013, v. 49, n. 6, p. 1038, doi. 10.1165/rcmb.2013-0089OC
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- Article
A<sub>2B</sub> Adenosine Receptors Induce IL-19 from Bronchial Epithelial Cells, Resulting in TNF-α Increase.
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- American Journal of Respiratory Cell & Molecular Biology, 2006, v. 35, n. 5, p. 587, doi. 10.1165/rcmb.2005-0476OC
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- Article
Synergy between A<sub>2B</sub> Adenosine Receptors and Hypoxia in Activating Human Lung Fibroblasts.
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- American Journal of Respiratory Cell & Molecular Biology, 2005, v. 32, n. 1, p. 2, doi. 10.1165/rcmb.2004-0103OC
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- Article
A<sub>2B</sub> Adenosine Receptors Increase Cytokine Release by Bronchial Smooth Muscle Cells.
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- American Journal of Respiratory Cell & Molecular Biology, 2004, v. 30, n. 1, p. 118, doi. 10.1165/rcmb.2003-0118OC
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- Article
CVT-4325 Inhibits Myocardial Fatty Acid Uptake and Improves Left Ventricular Systolic Function without Increasing Myocardial Oxygen Consumption in Dogs with Chronic Heart Failure.
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- Cardiovascular Drugs & Therapy, 2007, v. 21, n. 1, p. 9, doi. 10.1007/s10557-006-0496-5
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- Article
Cardiac Electrophysiology and Pharmacology of Adenosine.
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- Journal of Cardiovascular Electrophysiology, 1990, v. 1, n. 4, p. 327
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- Publication type:
- Article
In silico assessment of drug safety in human heart applied to late sodium current blockers.
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- Channels (19336950), 2013, v. 7, n. 4, p. 249, doi. 10.4161/chan.24905
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- Article
Ranolazine block of human Na<sub>v</sub>1.4 sodium channels and paramyotonia congenita mutants.
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- Channels (19336950), 2011, v. 5, n. 2, p. 161, doi. 10.4161/chan.5.2.14851
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- Article
Anti-Diabetic Effects of CVT-3619, Metformin and Pioglitazone Alone and Combined in ZDF Rats.
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- Diabetes, 2007, v. 56, p. A132
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- Publication type:
- Article
Expression and function of A<sub>2B</sub> adenosine receptors in the U87MG tumor cells.
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- Drug Development Research, 2003, v. 58, n. 4, p. 405, doi. 10.1002/ddr.10212
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- Article
Characterization of the potency, selectivity, and pharmacokinetic profile for six adenosine A<sub>2A</sub> receptor antagonists.
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- Naunyn-Schmiedeberg's Archives of Pharmacology, 2007, v. 375, n. 2, p. 133, doi. 10.1007/s00210-007-0135-0
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- Article
Contribution of I<sub>K,ADO</sub> to the negative dromotropic effect of adenosine.
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- Basic Research in Cardiology, 2002, v. 97, n. 4, p. 286, doi. 10.1007/s00395-002-0349-8
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- Article
Potentiation of the negative dromotropic effect of adenosine by rapid heart rates: possible ionic mechanism.
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- Basic Research in Cardiology, 2002, v. 97, n. 4, p. 295, doi. 10.1007/s00395-002-0354-y
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- Article
Multimodal mechanisms and enhanced efficiency of atrial fibrillation cardioversion by pulmonary delivery of a novel flecainide formulation.
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- Journal of Cardiovascular Electrophysiology, 2020, v. 31, n. 1, p. 205, doi. 10.1111/jce.14289
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- Article
Reduction of Free Fatty Acids, Safety, and Pharmacokinetics of Oral GS-9667, an A<sub>1</sub> Adenosine Receptor Partial Agonist.
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- Journal of Clinical Pharmacology, 2013, v. 53, n. 4, p. 385, doi. 10.1002/jcph.9
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- Article
Adenosine: Cardiac Electrophysiology.
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- Pacing & Clinical Electrophysiology, 1991, v. 14, n. 11, p. 1672, doi. 10.1111/j.1540-8159.1991.tb02742.x
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- Article
Abnormal left ventricular relaxation in patients with long QT syndrome.
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- European Heart Journal, 2009, v. 30, n. 22, p. 2813, doi. 10.1093/eurheartj/ehp444
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- Article
Effect of autonomic influences to induce triggered activity in muscular sleeves extending into the coronary sinus of the canine heart and its suppression by ranolazine.
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- Journal of Cardiovascular Electrophysiology, 2019, v. 30, n. 2, p. 230, doi. 10.1111/jce.13770
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- Article
Pulmonary delivery of flecainide causes a rate‐dependent predominant effect on atrial compared with ventricular depolarization duration revealed by intracardiac recordings in an intact porcine model.
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- Journal of Cardiovascular Electrophysiology, 2018, v. 29, n. 11, p. 1563, doi. 10.1111/jce.13708
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- Article
The Selective Cardiac Late Sodium Current Inhibitor GS-458967 Suppresses Autonomically Triggered Atrial Fibrillation in an Intact Porcine Model.
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- Journal of Cardiovascular Electrophysiology, 2015, v. 26, n. 12, p. 1364, doi. 10.1111/jce.12824
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- Article
Combined Actions of Ivabradine and Ranolazine Reduce Ventricular Rate During Atrial Fibrillation.
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- Journal of Cardiovascular Electrophysiology, 2015, v. 26, n. 3, p. 329, doi. 10.1111/jce.12569
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- Article
Dronedarone's Inhibition of I<sub>f</sub> Current Is the Primary Mechanism Responsible for Its Bradycardic Effect.
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- Journal of Cardiovascular Electrophysiology, 2013, v. 24, n. 8, p. 914, doi. 10.1111/jce.12155
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- Article
Ranolazine Exerts Potent Effects on Atrial Electrical Properties and Abbreviates Atrial Fibrillation Duration in the Intact Porcine Heart.
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- Journal of Cardiovascular Electrophysiology, 2009, v. 20, n. 7, p. 796, doi. 10.1111/j.1540-8167.2009.01437.x
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- Article
Potent Antiarrhythmic Effects of Chronic Amiodarone in Canine Pulmonary Vein Sleeve Preparations.
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- Journal of Cardiovascular Electrophysiology, 2009, v. 20, n. 7, p. 803, doi. 10.1111/j.1540-8167.2009.01449.x
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- Publication type:
- Article
Effect of Ranolazine on Ventricular Vulnerability and Defibrillation Threshold in the Intact Porcine Heart.
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- Journal of Cardiovascular Electrophysiology, 2008, v. 19, n. 10, p. 1073, doi. 10.1111/j.1540-8167.2008.01204.x
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- Publication type:
- Article
The Role of Sodium Channel Current in Modulating Transmural Dispersion of Repolarization and Arrhythmogenesis.
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- Journal of Cardiovascular Electrophysiology, 2006, v. 17, p. S79, doi. 10.1111/j.1540-8167.2006.00388.x
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- Publication type:
- Article
Ranolazine Improves Abnormal Repolarization and Contraction in Left Ventricular Myocytes of Dogs with Heart Failure by Inhibiting Late Sodium Current.
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- Journal of Cardiovascular Electrophysiology, 2006, v. 17, p. S169, doi. 10.1111/j.1540-8167.2006.00401.x
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- Publication type:
- Article
Potentiating Effect of Acetylcholine on Stimulation by Isoproterenol of L-Type Ca<sup>2+</sup> Current and Arrhythmogenic Triggered Activity in Guinea Pig Ventricular Myocytes.
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- Journal of Cardiovascular Electrophysiology, 1998, v. 9, n. 7, p. 718, doi. 10.1111/j.1540-8167.1998.tb00959.x
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- Article
Modulation of late sodium current by Ca<sup>2+</sup>-calmodulin-dependent protein kinase II, protein kinase C and Ca<sup>2+</sup> during hypoxia in rabbit ventricular myocytes.
- Published in:
- Experimental Physiology, 2017, v. 102, n. 7, p. 818, doi. 10.1113/EP085990
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- Article
Protein kinase C and Ca<sup>2+</sup>-calmodulin-dependent protein kinase II mediate the enlarged reverse I<sub>NCX</sub> induced by ouabain-increased late sodium current in rabbit ventricular myocytes.
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- Experimental Physiology, 2015, v. 100, n. 4, p. 399, doi. 10.1113/expphysiol.2014.083972
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- Article
The A<sub>2B</sub> adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease.
- Published in:
- FASEB Journal, 2012, v. 26, n. 6, p. 2546, doi. 10.1096/fj.11-200907
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- Publication type:
- Article
Functional modulation of atrio-ventricular conduction by enhanced late sodium current and calcium-dependent mechanisms in Scn5a1798insD/+ mice.
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- 2020
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- Publication type:
- journal article
Sodium channel block by ranolazine in an experimental model of stretch-related atrial fibrillation: prolongation of interatrial conduction time and increase in post-repolarization refractoriness.
- Published in:
- EP: Europace, 2013, v. 15, n. 5, p. 761, doi. 10.1093/europace/eus399
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- Article
The risk of sudden cardiac death in patients with non-ST elevation acute coronary syndrome and prolonged QTc interval: effect of ranolazine.
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- EP: Europace, 2013, v. 15, n. 3, p. 429, doi. 10.1093/europace/eus400
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- Article
Mechanisms of ranolazine's dual protection against atrial and ventricular fibrillation.
- Published in:
- EP: Europace, 2013, v. 15, n. 3, p. 317, doi. 10.1093/europace/eus380
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- Publication type:
- Article