Works by Azuma, Junichi

Results: 47

Cellular characterization of an in-vitro cell culture model of seal-induced cardiac ischaemia.

Published in:

Journal of Pharmacy & Pharmacology, 2001, v. 53, n. 3, p. 379, doi. 10.1211/0022357011775433

By:

Takahashi, Kyoko;
Ohyabu, Yuko;
Schaffer, Stephen W.;
Azuma, Junichi

Publication type:

Article

Pharmacokinetics of pegylated recombinant human megakaryocyte growth and development factor in healthy volunteers and patients with hematological disorders.

Published in:

European Journal of Haematology, 2004, v. 73, n. 4, p. 269, doi. 10.1111/j.1600-0609.2004.00288.x

By:

Tanaka, Hideji;
Takama, Hirotaka;
Vasumasa Arai;
Junichi Azuma;
Ohno, Ryuzo;
Vasuo Ikeda;
Hideaki Mizoguchi

Publication type:

Article

Association between osteopontin promoter variants and diastolic dysfunction in hypertensive heart in the Japanese population.

Published in:

Hypertension Research, 2011, v. 34, n. 10, p. 1141, doi. 10.1038/hr.2011.102

By:

Nakayama, Hiroyuki;
Nagai, Hiromi;
Matsumoto, Kyotaka;
Oguro, Ryosuke;
Sugimoto, Ken;
Kamide, Kei;
Ohishi, Mitsuru;
Katsuya, Tomohiro;
Okamoto, Hiroshi;
Maeda, Makiko;
Komamura, Kazuo;
Azuma, Junichi;
Rakugi, Hiromi;
Fujio, Yasushi

Publication type:

Article

NAT2 genotype guided regimen reduces isoniazid-induced liver injury and early treatment failure in the 6-month four-drug standard treatment of tuberculosis: A randomized controlled trial for pharmacogenetics-based therapy.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 5, p. 1091, doi. 10.1007/s00228-012-1429-9

By:

Azuma, Junichi;
Ohno, Masako;
Kubota, Ryuji;
Yokota, Soichiro;
Nagai, Takayuki;
Tsuyuguchi, Kazunari;
Okuda, Yasuhisa;
Takashima, Tetsuya;
Kamimura, Sayaka;
Fujio, Yasushi;
Kawase, Ichiro

Publication type:

Article

The relationship between clinical pharmacokinetics of aripiprazole and CYP2D6 genetic polymorphism: effects of CYP enzyme inhibition by coadministration of paroxetine or fluvoxamine.

Published in:

European Journal of Clinical Pharmacology, 2012, v. 68, n. 1, p. 29, doi. 10.1007/s00228-011-1094-4

By:

Azuma, Junichi;
Hasunuma, Tomoko;
Kubo, Masanori;
Miyatake, Masaya;
Koue, Toshiko;
Higashi, Koushi;
Fujiwara, Tsutomu;
Kitahara, Sachiko;
Katano, Tamiki;
Hara, Sumiko

Publication type:

Article

Influence of clinical and genetic factors on warfarin dose requirements among Japanese patients.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 11, p. 1097, doi. 10.1007/s00228-009-0685-9

By:

Ohno, Masako;
Yamamoto, Akiko;
Ono, Ayumu;
Miura, Genta;
Funamoto, Masanobu;
Takemoto, Yasuhiko;
Otsu, Kinya;
Kouno, Yasushi;
Tanabe, Tomoko;
Masunaga, Yuiko;
Nonen, Shinpei;
Fujio, Yasushi;
Azuma, Junichi

Publication type:

Article

Chronic heart failure: β-blockers and pharmacogenetics.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 1, p. 3, doi. 10.1007/s00228-008-0566-7

By:

Azuma, Junichi;
Nonen, Shinpei

Publication type:

Article

Dose-escalation study of isoniazid in healthy volunteers with the rapid acetylator genotype of arylamine N-acetyltransferase 2.

Published in:

European Journal of Clinical Pharmacology, 2007, v. 63, n. 10, p. 927, doi. 10.1007/s00228-007-0333-1

By:

Kubota, Ryuji;
Ohno, Masako;
Hasunuma, Tomoko;
Iijima, Hajime;
Azuma, Junichi

Publication type:

Article

Impact of CYP2D6*10 on mexiletine pharmacokinetics in healthy adult volunteers.

Published in:

European Journal of Clinical Pharmacology, 2003, v. 59, n. 5/6, p. 395, doi. 10.1007/s00228-003-0656-5

By:

Otani, Masahiro;
Fukuda, Tsuyoshi;
Naohara, Masakazu;
Maune, Hiromi;
Senda, Chiaki;
Yamamoto, Isamu;
Azuma, Junichi

Publication type:

Article

No major difference in inhibitory susceptibility between CYP2C9.1 and CYP2C9.3.

Published in:

European Journal of Clinical Pharmacology, 2003, v. 59, n. 3, p. 233, doi. 10.1007/s00228-003-0603-5

By:

Hanatani, Tadaaki;
Fukuda, Tsuyoshi;
Onishi, Sachi;
Funae, Yoshihiko;
Azuma, Junichi

Publication type:

Article

Isolation of Putative Glycoprotein Gene from Early Somatic Embryo of Carrot and its Possible Involvement in Somatic Embryo Development.

Published in:

Plant & Cell Physiology, 2004, v. 45, n. 11, p. 1658, doi. 10.1093/pcp/pch188

By:

Takahata, Kiminori;
Takeuchi, Miyuki;
Fujita, Minoru;
Azuma, Junichi;
Kamada, Hiroshi;
Sato, Fumihiko

Publication type:

Article

Bioequivalence of Rebamipide Granules and Tablets in Healthy Adult Male Volunteers.

Published in:

Clinical Drug Investigation, 2003, v. 23, n. 12, p. 771, doi. 10.2165/00044011-200323120-00002

By:

Hasegawa, Setsuo;
Sekino, Hisakuni;
Matsitoka, Osamu;
Saito, Kazunori;
Sekino, Hisayuki;
Morikawa, Aki;
Uchida, Kaya;
Koike, Masami;
Azuma, Junichi

Publication type:

Article

Diabetic Retinopathy Possibly Results From Poor Blood Sugar Control Associated With MTHFR Gene Polymorphism in Type 2 Diabetic Patients.

Published in:

Diabetes Care, 2003, v. 26, n. 6, p. 1948, doi. 10.2337/diacare.26.6.1948

By:

Maeda, Makiko;
Yamamoto, Isamu;
Fukuda, Masakatsu;
Nishida, Mari;
Fujitsu, Junko;
Nonen, Shinpei;
Igarashi, Tsuyoshi;
Motomura, Takashi;
Inaba, Makiko;
Fujio, Yasushi;
Azuma, Junichi

Publication type:

Article

MTHFR gene polymorphism as a risk factor for diabetic retinopathy in type 2 diabetic patients without serum creatinine elevation.

Published in:

2003

By:

Maeda, Makiko;
Yamamoto, Isamu;
Fukuda, Masakatsu;
Nishida, Mari;
Fujitsu, Junko;
Nonen, Shinpei;
Igarashi, Tsuyoshi;
Motomura, Takashi;
Motomura, Takasi;
Inaba, Makiko;
Fujio, Yasushi;
Azuma, Junichi;
Azuma, Unichi

Publication type:

Letter

Genetic polymorphisms of CYP17A1 in steroidogenesis pathway are associated with risk of progression to castration-resistant prostate cancer in Japanese men receiving androgen deprivation therapy.

Published in:

International Journal of Clinical Oncology, 2013, v. 18, n. 4, p. 711, doi. 10.1007/s10147-012-0430-8

By:

Yamada, Takeshi;
Nakayama, Masashi;
Shimizu, Tomohito;
Nonen, Shinpei;
Nakai, Yasutomo;
Nishimura, Kazuo;
Fujio, Yasushi;
Okuyama, Akihiko;
Azuma, Junichi;
Nonomura, Norio

Publication type:

Article

Coronary Angiographic Features within 48 Hours from Onset of Non-Q Wave Myocardial Infarction with R Wave Regression and No ST Segment Depression.

Published in:

Cardiology, 1990, v. 77, n. 2, p. 121, doi. 10.1159/000174592

By:

Park, Seung-Eun;
Tani, Akihiro;
Minamino, Takazo;
Azuma, Junichi;
Kishimoto, Susumu

Publication type:

Article

Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy

Published in:

Modern Rheumatology, 2009, v. 19, n. 1, p. 12, doi. 10.3109/s10165-008-0125-1

By:

Nishimoto, Norihiro;
Miyasaka, Nobuyuki;
Yamamoto, Kazuhiko;
Kawai, Shinichi;
Takeuchi, Tsutomu;
Azuma, Junichi;
Kishimoto, Tadamitsu

Publication type:

Article

Involvement of Na+-Ca2+ Exchanger in Reperfusion-induced Delayed Cell Death of Cultured Rat Astrocytes.

Published in:

European Journal of Neuroscience, 1996, v. 8, n. 5, p. 951, doi. 10.1111/j.1460-9568.1996.tb01582.x

By:

Matsuda, Toshio;
Takuma, Kazuhiro;
Nishiguchi, Emi;
Asano, Shoichi;
Hashimoto, Hitoshi;
Azuma, Junichi;
Baba, Akemichi

Publication type:

Article

Atrogin-1 ubiquitin ligase is upregulated by doxorubicin via p38-MAP kinase in cardiac myocytes.

Published in:

Cardiovascular Research, 2008, v. 79, n. 1, p. 89, doi. 10.1093/cvr/cvn076

By:

Yamamoto, Yasuhiro;
Hoshino, Yuki;
Ito, Takashi;
Nariai, Tetsuro;
Mohri, Tomomi;
Obana, Masanori;
Hayata, Nozomi;
Uozumi, Yoriko;
Maeda, Makiko;
Fujio, Yasushi;
Azuma, Junichi

Publication type:

Article

STAT3 mediates cardioprotection against ischemia/reperfusion injury through metallothionein induction in the heart

Published in:

Cardiovascular Research, 2005, v. 65, n. 2, p. 428, doi. 10.1016/j.cardiores.2004.10.021

By:

Oshima, Yuichi;
Fujio, Yasushi;
Nakanishi, Tsuyoshi;
Itoh, Norio;
Yamamoto, Yasuhiro;
Negoro, Shinji;
Tanaka, Keiichi;
Kishimoto, Tadamitsu;
Kawase, Ichiro;
Azuma, Junichi

Publication type:

Article

Effect of β-alanine treatment on mitochondrial taurine level and 5-taurinomethyluridine content.

Published in:

Journal of Biomedical Science, 2010, v. 17, p. 1, doi. 10.1186/1423-0127-17-S1-S25

By:

Chian Ju Jong;
Ito, Takashi;
Mozaffari, Mahmood;
Azuma, Junichi;
Schaffer, Stephen

Publication type:

Article

Cardiac and skeletal muscle abnormality in taurine transporter-knockout mice.

Published in:

Journal of Biomedical Science, 2010, v. 17, p. 1, doi. 10.1186/1423-0127-17-S1-S20

By:

Ito, Takashi;
Oishi, Shohei;
Takai, Mika;
Kimura, Yasushi;
Uozumi, Yoriko;
Fujio, Yasushi;
Schaffer, Stephen W.;
Azuma, Junichi

Publication type:

Article

Physiological roles of taurine in heart and muscle.

Published in:

Journal of Biomedical Science, 2010, v. 17, p. 1, doi. 10.1186/1423-0127-17-S1-S2

By:

Schaffer, Stephen W.;
Chian Ju Jong;
C., Ramila K.;
Azuma, Junichi

Publication type:

Article

Platelet activating factor induces cytoskeletal reorganization through Rho family pathway in THP-1 macrophages

Published in:

FEBS Letters, 2005, v. 579, n. 18, p. 4038, doi. 10.1016/j.febslet.2005.06.022

By:

Sumita, Chinuyo;
Yamane, Masako;
Matsuda, Takahisa;
Maeda, Makiko;
Nariai, Tetsuro;
Fujio, Yasushi;
Azuma, Junichi

Publication type:

Article

Signals through gp130 upregulate Wnt5a and contribute to cell adhesion in cardiac myocytes

Published in:

FEBS Letters, 2004, v. 573, n. 1-3, p. 202, doi. 10.1016/j.febslet.2004.07.082

By:

Fujio, Yasushi;
Matsuda, Takahisa;
Oshima, Yuichi;
Maeda, Makiko;
Mohri, Tomomi;
Ito, Takashi;
Takatani, Tomoka;
Hirata, Mayo;
Nakaoka, Yoshikazu;
Kimura, Ryusuke;
Kishimoto, Tadamitsu;
Azuma, Junichi

Publication type:

Article

Effect of taurine and potential interactions with caffeine on cardiovascular function.

Published in:

Amino Acids, 2014, v. 46, n. 5, p. 1147, doi. 10.1007/s00726-014-1708-0

By:

Schaffer, Stephen;
Shimada, Kayoko;
Jong, Chian;
Ito, Takashi;
Azuma, Junichi;
Takahashi, Kyoko

Publication type:

Article

Role of taurine in the pathologies of MELAS and MERRF.

Published in:

Amino Acids, 2014, v. 46, n. 1, p. 47, doi. 10.1007/s00726-012-1414-8

By:

Schaffer, Stephen;
Jong, Chian;
Ito, Takashi;
Azuma, Junichi

Publication type:

Article

Effect of taurine on ischemia-reperfusion injury.

Published in:

Amino Acids, 2014, v. 46, n. 1, p. 21, doi. 10.1007/s00726-012-1378-8

By:

Schaffer, Stephen;
Jong, Chian;
Ito, Takashi;
Azuma, Junichi

Publication type:

Article

Clinical significance of taurine.

Published in:

2014

By:

Schaffer, Stephen;
Ito, Takashi;
Azuma, Junichi

Publication type:

Editorial

The effect of taurine on chronic heart failure: actions of taurine against catecholamine and angiotensin II.

Published in:

Amino Acids, 2014, v. 46, n. 1, p. 111, doi. 10.1007/s00726-013-1507-z

By:

Ito, Takashi;
Schaffer, Stephen;
Azuma, Junichi

Publication type:

Article

Mechanism underlying the antioxidant activity of taurine: prevention of mitochondrial oxidant production.

Published in:

Amino Acids, 2012, v. 42, n. 6, p. 2223, doi. 10.1007/s00726-011-0962-7

By:

Jong, Chian;
Azuma, Junichi;
Schaffer, Stephen

Publication type:

Article

The potential usefulness of taurine on diabetes mellitus and its complications.

Published in:

Amino Acids, 2012, v. 42, n. 5, p. 1529, doi. 10.1007/s00726-011-0883-5

By:

Ito, Takashi;
Schaffer, Stephen;
Azuma, Junichi

Publication type:

Article

Polymorphisms of CYP2D6 Gene and Gefitinib-Induced Hepatotoxicity.

Published in:

Clinical Lung Cancer, 2013, v. 14, n. 5, p. 502, doi. 10.1016/j.cllc.2013.03.003

By:

Takayuki Takimoto;
Takashi Kijima;
Yasushi Otani;
Shinpei Nonen;
Yoshinobu Namba;
Masahide Mori;
Soichiro Yokota;
Seigo Minami;
Kiyoshi Komuta;
Junji Uchida;
Fumio Imamura;
Mitsugi Furukawa;
Naotoshi Tsuruta;
Yasushi Fujio;
Junichi Azuma;
Isao Tachibana;
Atsushi Kumanogoh

Publication type:

Article

Role of antioxidant activity of taurine in diabetes.

Published in:

Canadian Journal of Physiology & Pharmacology, 2009, v. 87, n. 2, p. 91, doi. 10.1139/Y08-110

By:

Schaffer, Stephen W.;
Azuma, Junichi;
Mozaffari, Mahmood

Publication type:

Article

Graphic Emoticons as a Future Universal Symbolic Language.

Published in:

Approaches to Translation Studies, 2012, v. 36, p. 61

By:

Azuma, Junichi

Publication type:

Article

Cardioprotective effects of nicorandil on isoproterenol-induced injury.

Published in:

Drug Development Research, 1991, v. 22, n. 3, p. 229, doi. 10.1002/ddr.430220305

By:

Ohta, Hideyuki;
Azuma, Junichi;
Tanaka, Yuya;
Takihara, Keiko;
Hamaguchi, Tomoyuki;
Awata, Nobuhisa;
Sawamura, Akihiko;
Sperelakis, Nicholas;
Kishimoto, Susumu

Publication type:

Article

Cardioprotective effects of nicorandil on calcium paradox-induced injury.

Published in:

Drug Development Research, 1990, v. 19, n. 1, p. 91, doi. 10.1002/ddr.430190109

By:

Hamaguchi, Tomoyuki;
Azuma, Junichi;
Takihara, Keiko;
Ohta, Hideyuki;
Harada, Hisato;
Sperelakis, Nicholas;
Kishimoto, Susumu

Publication type:

Article

No positive association between adrenergic receptor variants of α2cDel322–325, β1Ser49, β1Arg389 and the risk for heart failure in the Japanese population.

Published in:

British Journal of Clinical Pharmacology, 2005, v. 60, n. 4, p. 414, doi. 10.1111/j.1365-2125.2005.02447.x

By:

Nonen, Shinpei;
Okamoto, Hiroshi;
Akino, Masatoshi;
Matsui, Yutaka;
Fujio, Yasushi;
Yoshiyama, Minoru;
Takemoto, Yasuhiko;
Yoshikawa, Junichi;
Azuma, Junichi;
Kitabatake, Akira

Publication type:

Article

Effect of the CYP2D6*10 genotype on venlafaxine pharmacokinetics in healthy adult volunteers.

Published in:

British Journal of Clinical Pharmacology, 1999, v. 47, n. 4, p. 450, doi. 10.1046/j.1365-2125.1999.00913.x

By:

Fukuda, Tsuyoshi;
Yamamoto, Isamu;
Nishida, Yuko;
Zhou, Qian;
Ohno, Masako;
Takada, Kanji;
Azuma, Junichi

Publication type:

Article

Knockout of the TauT Gene Predisposes C57BL/6 Mice to Streptozotocin-Induced Diabetic Nephropathy.

Published in:

PLoS ONE, 2015, v. 10, n. 1, p. 1, doi. 10.1371/journal.pone.0117718

By:

Han, Xiaobin;
Patters, Andrea B.;
Ito, Takashi;
Azuma, Junichi;
Schaffer, Stephen W.;
Chesney, Russell W.

Publication type:

Article

Tissue Depletion of Taurine Accelerates Skeletal Muscle Senescence and Leads to Early Death in Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107409

By:

Ito, Takashi;
Yoshikawa, Natsumi;
Inui, Takaaki;
Miyazaki, Natsuko;
Schaffer, Stephen W.;
Azuma, Junichi

Publication type:

Article

Microsomal Enzyme Induction and Clinical Aggravation of Porphyria: The Evaluation of Human Urinary 6β-Hydroxycortisol/Cortisol Ratio as the Index of Hepatic CYP3A4 Activity.

Published in:

Journal of Clinical Pharmacology, 2002, v. 42, n. 12, p. 1374, doi. 10.1177/0091270002042012012

By:

Uejima, Etsuko;
Takahashi, Kyoko;
Morisaki, Tomoko;
Takahashi, Koichi;
Ohno, Masako;
Nishida, Yuko;
Moriya, Masayuki;
Kaido, Misako;
Abe, Kazuo;
Sakoda, Saburo;
Yanagihara, Takehiko;
Kurokawa, Nobuo;
Azuma, Junichi

Publication type:

Article

Warfarin dose requirement for patients with both VKORC1 3673A/A and CYP2C93/3 genotypes.

Published in:

2006

By:

Fukuda, Tsuyoshi;
Tanabe, Tomoko;
Ohno, Masako;
Tougou, Katsuhiko;
Fujio, Yasushi;
Azuma, Junichi;
Yamamoto, Isamu;
Takeda, Akira

Publication type:

Letter

Tissue Taurine Depletion Alters Metabolic Response to Exercise and Reduces Running Capacity in Mice.

Published in:

Journal of Amino Acids, 2014, p. 1, doi. 10.1155/2014/964680

By:

Takashi Ito;
Natsumi Yoshikawa;
Schaffer, Stephen W.;
Junichi Azuma

Publication type:

Article

Pharmacokinetics, Pharmacodynamics and Safety of Tolvaptan, A Novel, Oral, Selective Nonpeptide AVP V-receptor Antagonist: Results of Single- and Multiple-Dose Studies in Healthy Japanese Male Volunteers.

Published in:

Cardiovascular Drugs & Therapy, 2011, v. 25, p. 5, doi. 10.1007/s10557-011-6299-3

By:

Kim, Seong;
Hasunuma, Tomoko;
Sato, Osamu;
Okada, Tadashi;
Kondo, Mitsuhiro;
Azuma, Junichi

Publication type:

Article

No Association of TPH1 218A/C Polymorphism with Treatment Response and Intolerance to SSRIs in Japanese Patients with Major Depression.

Published in:

Neuropsychobiology, 2007, v. 56, n. 4, p. 167, doi. 10.1159/000119734

By:

Kato, Masaki;
Wakeno, Masataka;
Okugawa, Gaku;
Fukuda, Tsuyoshi;
Azuma, Junichi;
Kinoshita, Toshihiko;
Serretti, Alessandro

Publication type:

Article

Effects of the Serotonin Type 2A, 3A and 3B Receptor and the Serotonin Transporter Genes on Paroxetine and Fluvoxamine Efficacy and Adverse Drug Reactions in Depressed Japanese Patients.

Published in:

Neuropsychobiology, 2006, v. 53, n. 4, p. 186, doi. 10.1159/000094727

By:

Kato, Masaki;
Fukuda, Tsuyoshi;
Wakeno, Masataka;
Fukuda, Kazuhiro;
Okugawa, Gaku;
Ikenaga, Yuka;
Yamashita, Megumi;
Takekita, Yoshiteru;
Nobuhara, Kenji;
Azuma, Junichi;
Kinoshita, Toshihiko

Publication type:

Article