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Reprogramming of profibrotic macrophages for treatment of bleomycin‐induced pulmonary fibrosis.
Published in:
EMBO Molecular Medicine, 2020, v. 12, n. 8, p. 1, doi. 10.15252/emmm.202012034
By:
- Zhang, Fenghua;
- Ayaub, Ehab A;
- Wang, Bingbing;
- Puchulu‐Campanella, Estela;
- Li, Yen‐Hsing;
- Hettiarachchi, Suraj U;
- Lindeman, Spencer D;
- Luo, Qian;
- Rout, Sasmita;
- Srinivasarao, Madduri;
- Cox, Abigail;
- Tsoyi, Konstantin;
- Nickerson‐Nutter, Cheryl;
- Rosas, Ivan O;
- Low, Philip S
Publication type:
Article
GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis.
Published in:
Journal of Pathology, 2016, v. 239, n. 4, p. 411, doi. 10.1002/path.4738
By:
- Ayaub, Ehab A;
- Kolb, Philipp S;
- Mohammed‐Ali, Zahraa;
- Tat, Victor;
- Murphy, James;
- Bellaye, Pierre‐Simon;
- Shimbori, Chiko;
- Boivin, Felix J;
- Lai, Rocky;
- Lynn, Edward G;
- Lhoták, Šárka;
- Bridgewater, Darren;
- Kolb, Martin RJ;
- Inman, Mark D;
- Dickhout, Jeffrey G;
- Austin, Richard C;
- Ask, Kjetil
Publication type:
Article
Characterization of the COPD alveolar niche using single-cell RNA sequencing.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28062-9
By:
- Sauler, Maor;
- McDonough, John E.;
- Adams, Taylor S.;
- Kothapalli, Neeharika;
- Barnthaler, Thomas;
- Werder, Rhiannon B.;
- Schupp, Jonas C.;
- Nouws, Jessica;
- Robertson, Matthew J.;
- Coarfa, Cristian;
- Yang, Tao;
- Chioccioli, Maurizio;
- Omote, Norihito;
- Cosme Jr, Carlos;
- Poli, Sergio;
- Ayaub, Ehab A.;
- Chu, Sarah G.;
- Jensen, Klaus H.;
- Gomez, Jose L.;
- Britto, Clemente J.
Publication type:
Article
Overexpression of OSM and IL-6 impacts the polarization of pro-fibrotic macrophages and the development of bleomycin-induced lung fibrosis.
Published in:
Scientific Reports, 2017, v. 7, n. 1, p. 1, doi. 10.1038/s41598-017-13511-z
By:
- Ayaub, Ehab A.;
- Dubey, Anisha;
- Imani, Jewel;
- Botelho, Fernando;
- Kolb, Martin R. J.;
- Richards, Carl D.;
- Ask, Kjetil
Publication type:
Article
Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection.
Published in:
PLoS Pathogens, 2022, v. 18, n. 5, p. 1, doi. 10.1371/journal.ppat.1010471
By:
- Lee, Amanda J.;
- Feng, Emily;
- Chew, Marianne V.;
- Balint, Elizabeth;
- Poznanski, Sophie M.;
- Giles, Elizabeth;
- Zhang, Ali;
- Marzok, Art;
- Revill, Spencer D.;
- Vahedi, Fatemeh;
- Dubey, Anisha;
- Ayaub, Ehab;
- Jimenez-Saiz, Rodrigo;
- McGrath, Joshua J. C.;
- Ritchie, Tyrah M.;
- Jordana, Manel;
- Jonigk, Danny D.;
- Ackermann, Maximilian;
- Ask, Kjetil;
- Miller, Matthew
Publication type:
Article
FK506-Binding Protein 13 Expression Is Upregulated in Interstitial Lung Disease and Correlated with Clinical Severity: A Potentially Protective Role.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2021, v. 64, n. 2, p. 235, doi. 10.1165/rcmb.2020-0121OC
By:
- Tat, Victor;
- Ayaub, Ehab A.;
- Ayoub, Anmar;
- Vierhout, Megan;
- Naiel, Safaa;
- Padwal, Manreet K.;
- Abed, Soumeya;
- Mekhael, Olivia;
- Tandon, Karun;
- Revill, Spencer D.;
- Yousof, Tamana;
- Bellaye, Pierre-Simon;
- Kolb, Philipp S.;
- Dvorkin-Gheva, Anna;
- Naqvi, Asghar;
- Cutz, Jean-Claude;
- Hambly, Nathan;
- Kato, Jiro;
- Vaughan, Martha;
- Moss, Joel
Publication type:
Article
Palmitic Acid--Rich High-Fat Diet Exacerbates Experimental Pulmonary Fibrosis by Modulating Endoplasmic Reticulum Stress.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2019, v. 61, n. 6, p. 737, doi. 10.1165/rcmb.2018-0324OC
By:
- Chu, Sarah G.;
- Villalba, Julian A.;
- Liang, Xiaoliang;
- Xiong, Kevin;
- Tsoyi, Konstantin;
- Ith, Bonna;
- Ayaub, Ehab A.;
- Tatituri, Raju V.;
- Byers, Derek E.;
- Fong-Fu Hsu;
- El-Chemaly, Souheil;
- Kim, Edy Y.;
- Yuanyuan Shi;
- Rosas, Ivan O.
Publication type:
Article
Disruption of Calcium Signaling in Fibroblasts and Attenuation of Bleomycin-Induced Fibrosis by Nifedipine.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2015, v. 53, n. 4, p. 450, doi. 10.1165/rcmb.2015-0009OC
By:
- Mukherjee, Subhendu;
- Ayaub, Ehab A.;
- Murphy, James;
- Lu, Chao;
- Kolb, Martin;
- Ask, Kjetil;
- Janssen, Luke J.
Publication type:
Article
Mesenchymal stromal cell‐derived syndecan‐2 regulates the immune response during sepsis to foster bacterial clearance and resolution of inflammation.
Published in:
FEBS Journal, 2022, v. 289, n. 2, p. 417, doi. 10.1111/febs.16154
By:
- Han, Junwen;
- Shi, Yuanyuan;
- Willis, Gareth;
- Imani, Jewel;
- Kwon, Min‐Young;
- Li, Gu;
- Ayaub, Ehab;
- Ghanta, Sailaja;
- Ng, Julie;
- Hwang, Narae;
- Tsoyi, Konstantin;
- El‐Chemaly, Souheil;
- Kourembanas, Stella;
- Mitsialis, S. Alex;
- Rosas, Ivan O.;
- Liu, Xiaoli;
- Perrella, Mark A.
Publication type:
Article
Myeloid‐specific deletion of activating transcription factor 6 alpha increases CD11b<sup>+</sup> macrophage subpopulations and aggravates lung fibrosis.
Published in:
Immunology & Cell Biology, 2023, v. 101, n. 5, p. 412, doi. 10.1111/imcb.12637
By:
- Mekhael, Olivia;
- Revill, Spencer D;
- Hayat, Aaron I;
- Cass, Steven P;
- MacDonald, Kyle;
- Vierhout, Megan;
- Ayoub, Anmar;
- Reihani, Amir;
- Padwal, Manreet;
- Imani, Jewel;
- Ayaub, Ehab;
- Yousof, Tamana;
- Dvorkin‐Gheva, Anna;
- Rullo, Anthony;
- Hirota, Jeremy A;
- Richards, Carl D;
- Bridgewater, Darren;
- Stämpfli, Martin R;
- Hambly, Nathan;
- Naqvi, Asghar
Publication type:
Article
IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M.
Published in:
Mediators of Inflammation, 2020, p. 1, doi. 10.1155/2020/4087315
By:
- Botelho, Fernando;
- Dubey, Anisha;
- Ayaub, Ehab A.;
- Park, Rex;
- Yip, Ashley;
- Humbles, Allison;
- Kolbeck, Roland;
- Richards, Carl D.
Publication type:
Article
IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M.
Published in:
Mediators of Inflammation, 2020, p. 1, doi. 10.1155/2020/4087315
By:
- Botelho, Fernando;
- Dubey, Anisha;
- Ayaub, Ehab A.;
- Park, Rex;
- Yip, Ashley;
- Humbles, Allison;
- Kolbeck, Roland;
- Richards, Carl D.
Publication type:
Article
IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M.
Published in:
Mediators of Inflammation, 2020, p. 1, doi. 10.1155/2020/4087315
By:
- Botelho, Fernando;
- Dubey, Anisha;
- Ayaub, Ehab A.;
- Park, Rex;
- Yip, Ashley;
- Humbles, Allison;
- Kolbeck, Roland;
- Richards, Carl D.
Publication type:
Article
IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M.
Published in:
Mediators of Inflammation, 2020, p. 1, doi. 10.1155/2020/4087315
By:
- Botelho, Fernando;
- Dubey, Anisha;
- Ayaub, Ehab A.;
- Park, Rex;
- Yip, Ashley;
- Humbles, Allison;
- Kolbeck, Roland;
- Richards, Carl D.
Publication type:
Article
IL‐6 mediates ER expansion during hyperpolarization of alternatively activated macrophages.
Published in:
Immunology & Cell Biology, 2019, v. 97, n. 2, p. 203, doi. 10.1111/imcb.12212
By:
- Ayaub, Ehab A;
- Tandon, Karun;
- Padwal, Manreet;
- Imani, Jewel;
- Patel, Hemisha;
- Dubey, Anisha;
- Mekhael, Olivia;
- Upagupta, Chandak;
- Ayoub, Anmar;
- Dvorkin‐Gheva, Anna;
- Murphy, James;
- Kolb, Philipp S;
- Lhotak, Sarka;
- Dickhout, Jeffrey G;
- Austin, Rick C;
- Kolb, Martin R J;
- Richards, Carl D;
- Ask, Kjetil
Publication type:
Article
Separate roles of IL‐6 and oncostatin M in mouse macrophage polarization <italic>in vitro</italic> and <italic>in vivo</italic>.
Published in:
Immunology & Cell Biology, 2018, v. 96, n. 3, p. 257, doi. 10.1111/imcb.1035
By:
- Dubey, Anisha;
- Izakelian, Laura;
- Ayaub, Ehab A.;
- Ho, Lilian;
- Stephenson, Kyle;
- Wong, Steven;
- Kwofie, Karen;
- Austin, Richard C.;
- Botelho, Fernando;
- Ask, Kjetil;
- Richards, Carl D.
Publication type:
Article
Targeted inhibition of PI3 kinase/mTOR specifically in fibrotic lung fibroblasts suppresses pulmonary fibrosis in experimental models.
Published in:
Science Translational Medicine, 2020, v. 12, n. 567, p. 1, doi. 10.1126/scitranslmed.aay3724
By:
- Hettiarachchi, Suraj U.;
- Li, Yen-Hsing;
- Roy, Jyoti;
- Zhang, Fenghua;
- Puchulu-Campanella, Estela;
- Lindeman, Spencer D.;
- Srinivasarao, Madduri;
- Tsoyi, Konstantin;
- Liang, Xiaoliang;
- Ayaub, Ehab A.;
- Nickerson-Nutter, Cheryl;
- Rosas, Ivan O.;
- Low, Philip S.
Publication type:
Article

Found: 17