Works by Axtell, Robert C.

Results: 26

Gaining entry to an uninflamed brain.

Published in:

Nature Immunology, 2009, v. 10, n. 5, p. 453, doi. 10.1038/ni0509-453

By:

Axtell, Robert C;
Steinman, Lawrence

Publication type:

Article

The Role of B Cells in Primary Progressive Multiple Sclerosis.

Published in:

Frontiers in Neurology, 2021, v. 12, p. 1, doi. 10.3389/fneur.2021.680581

By:

Holloman, Jameson P.;
Axtell, Robert C.;
Monson, Nancy L.;
Wu, Gregory F.

Publication type:

Article

Reversal of Paralysis and Reduced Inflammation from Peripheral Administration of β-Amyloid in TH1 and TH17 Versions of Experimental Autoimmune Encephalomyelitis.

Published in:

Science Translational Medicine, 2012, v. 4, n. 145, p. 1, doi. 10.1126/scitranslmed.3004145

By:

Grant, Jacqueline L.;
Bou Ghosn, Eliver Eid;
Axtell, Robert C.;
Herges, Katja;
Kuipers, Hedwich F.;
Woodling, Nathan S.;
Andreasson, Katrin;
Herzenberg, Leonard A.;
Herzenberg, Leonore A.;
Steinman, Lawrence

Publication type:

Article

B-Lymphocyte-Mediated Delayed Cognitive Impairment following Stroke.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 5, p. 2145, doi. 10.1523/JNEUROSCI.4098-14.2015

By:

Doyle, Kristian P.;
Quach, Lisa N.;
Solé, Montse;
Axtell, Robert C.;
Nguyen, Thuy-Vi V.;
Soler-Llavina, Gilberto J.;
Jurado, Sandra;
Han, Juliet;
Steinman, Lawrence;
Longo, Frank M.;
Schneider, Julie A.;
Malenka, Robert C.;
Buckwalter, Marion S.

Publication type:

Article

Loss of Nrf2 exacerbates the visual deficits and optic neuritis elicited by experimental autoimmune encephalomyelitis.

Published in:

Molecular Vision, 2016, v. 22, p. 1

By:

Larabee, Chelsea M.;
Desai, Shruti;
Agasing, Agnieshka;
Georgescu, Constantin;
Wren, Jonathan D.;
Axtell, Robert C.;
Plafker, Scott M.

Publication type:

Article

Myelinspecific Th17 cells induce severe relapsing optic neuritis with irreversible loss of retinal ganglion cells in C57BL/6 mice.

Published in:

Molecular Vision, 2016, v. 22, p. 1

By:

Larabee, Chelsea M.;
Yang Hu;
Desai, Shruti;
Georgescu, Constantin;
Wren, Jonathan D.;
Axtell, Robert C.;
Plafker, Scott M.

Publication type:

Article

Interferon-β Intensifies Interleukin-23-Driven Pathogenicity of T Helper Cells in Neuroinflammatory Disease.

Published in:

Cells (2073-4409), 2021, v. 10, n. 8, p. 2139, doi. 10.3390/cells10082139

By:

Agasing, Agnieshka;
Quinn, James L.;
Kumar, Gaurav;
Axtell, Robert C.

Publication type:

Article

Erratum: Common variants in P2RY11 are associated with narcolepsy.

Published in:

2011

By:

Kornum, Birgitte R;
Kawashima, Minae;
Faraco, Juliette;
Lin, Ling;
Rico, Thomas J;
Hesselson, Stephanie;
Axtell, Robert C;
Kuipers, Hedwich;
Weiner, Karin;
Hamacher, Alexandra;
Kassack, Matthias U;
Han, Fang;
Knudsen, Stine;
Li, Jing;
Dong, Xiaosong;
Winkelmann, Juliane;
Plazzi, Giuseppe;
Nevsimalova, Sona;
Hong, Seung-Chul;
Honda, Yutaka

Publication type:

Correction Notice

Common variants in P2RY11 are associated with narcolepsy.

Published in:

Nature Genetics, 2011, v. 43, n. 1, p. 66, doi. 10.1038/ng.734

By:

Kornum, Birgitte R.;
Kawashima, Minae;
Faraco, Juliette;
Ling Lin;
Rico, Thomas J.;
Hesselson, Stephanie;
Axtell, Robert C.;
Kuipers, Hedwich;
Weiner, Karin;
Hamacher, Alexandra;
Kassack, Matthias U.;
Fang Han;
Knudsen, Stine;
Jing Li;
Xiaosong Dong;
Winkelmann8,9,10, Juliane;
Plazzi, Giuseppe;
Nevsimalova, Sona;
Seung-Chul Hong;
Honda, Yutaka

Publication type:

Article

Depleting tumor-specific Tregs at a single site eradicates disseminated tumors.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 7, p. 2447, doi. 10.1172/JCI64859

By:

Marabelle, Aurélien;
Kohrt, Holbrook;
Sagiv-Barfi, Idit;
Ajami, Bahareh;
Axtell, Robert C.;
Gang Zhou;
Rajapaksa, Ranjani;
Green, Michael R.;
Torchia, James;
Brody, Joshua;
Luong, Richard;
Rosenblum, Michael D.;
Steinman, Lawrence;
Levitsky, Hyam I.;
Tse, Victor;
Levy, Ronald

Publication type:

Article

Depleting tumor-specific Tregs at a single site eradicates disseminated tumors.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 6, p. 2447, doi. 10.1172/JCI64859

By:

Holbrook Kohrt, Aurélien;
Sagiv-Barfi, Idit;
Kohrt, Holbrook;
Ajami, Bahareh;
Axtell, Robert C.;
Gang Zhou;
Rajapaksa, Ranjani;
Green, Michael R.;
Torchia, James;
Brody, Joshua;
Luong, Richard;
Rosenblum, Michael D.;
Steinman, Lawrence;
Levitsky, Hyam I.;
Tse, Victor;
Levy, Ronald

Publication type:

Article

Role of TFH Cells in Promoting T Helper 17-Induced Neuroinflammation.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00382

By:

Quinn, James L.;
Kumar, Gaurav;
Agasing, Agnieshka;
Ko, Rose M.;
Axtell, Robert C.

Publication type:

Article

Dual Role of B Cells in Multiple Sclerosis.

Published in:

2023

By:

Kumar, Gaurav;
Axtell, Robert C.

Publication type:

Literature Review

Pertussis Toxin Inhibits Encephalitogenic T-Cell Infiltration and Promotes a B-Cell-Driven Disease during Th17-EAE.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 6, p. 2924, doi. 10.3390/ijms22062924

By:

Maria, Zahra;
Turner, Emma;
Agasing, Agnieshka;
Kumar, Gaurav;
Axtell, Robert C.;
Liguori, Maria

Publication type:

Article

Emerging Role of Follicular T Helper Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 10, p. 3233, doi. 10.3390/ijms19103233

By:

Quinn, James L.;
Axtell, Robert C.

Publication type:

Article

Piet Mondrian’s trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011.

Published in:

Multiple Sclerosis Journal, 2013, v. 19, n. 1, p. 5, doi. 10.1177/1352458512470730

By:

Steinman, Lawrence;
Axtell, Robert C;
Barbieri, Donald;
Bhat, Roopa;
Brownell, Sara E;
de Jong, Brigit A;
Dunn, Shannon E;
Grant, Jacqueline L;
Han, May H;
Ho, Peggy P;
Kuipers, Hedwich F;
Kurnellas, Michael P;
Ousman, Shalina S;
Rothbard, Jonathan B

Publication type:

Article

Protective effect of an elastase inhibitor in a neuromyelitis optica-like disease driven by a peptide of myelin oligodendroglial glycoprotein.

Published in:

Multiple Sclerosis Journal, 2012, v. 18, n. 4, p. 398, doi. 10.1177/1352458512440060

By:

Herges, Katja;
de Jong, Brigit A;
Kolkowitz, Ilan;
Dunn, Caitlin;
Mandelbaum, Gil;
Ko, Rose M;
Maini, Alexander;
Han, May H;
Killestein, Joep;
Polman, Chris;
Goodyear, Alexandra L;
Dunn, Jeffrey;
Steinman, Lawrence;
Axtell, Robert C

Publication type:

Article

Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation.

Published in:

Nature Immunology, 2013, v. 14, n. 11, p. 1166, doi. 10.1038/ni.2730

By:

Garris, Christopher S;
Wu, Linfeng;
Acharya, Swati;
Arac, Ahmet;
Blaho, Victoria A;
Huang, Yingxiang;
Moon, Byoung San;
Axtell, Robert C;
Ho, Peggy P;
Steinberg, Gary K;
Lewis, David B;
Sobel, Raymond A;
Han, David K;
Steinman, Lawrence;
Snyder, Michael P;
Hla, Timothy;
Han, May H

Publication type:

Article

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain.

Published in:

Molecular Therapy, 2011, v. 19, n. 10, p. 1769, doi. 10.1038/mt.2011.164

By:

Zhuang, Xiaoying;
Xiang, Xiaoyu;
Grizzle, William;
Sun, Dongmei;
Zhang, Shuangqin;
Axtell, Robert C;
Ju, Songwen;
Mu, Jiangyao;
Zhang, Lifeng;
Steinman, Lawrence;
Miller, Donald;
Zhang, Huang-Ge

Publication type:

Article

Antigen presentation and interferon signatures in B cells driven by localized ablative cancer immunotherapy correlate with extended survival.

Published in:

Theranostics, 2022, v. 12, n. 2, p. 639, doi. 10.7150/thno.65773

By:

Liu, Kaili;
Hoover, Ashley R.;
Krawic, Jason R.;
DeVette, Christa I.;
Xiao-Hong Sun;
Hildebrand, William H.;
Lang, Mark L.;
Axtell, Robert C.;
Chen, Wei R.

Publication type:

Article

IL-17 Contributes to the Development of Chronic Rejection in a Murine Heart Transplant Model.

Published in:

Journal of Clinical Immunology, 2010, v. 30, n. 2, p. 235, doi. 10.1007/s10875-009-9366-9

By:

Itoh, Satoshi;
Nakae, Susumu;
Axtell, Robert C.;
Velotta, Jeffrey B.;
Kimura, Naoyuki;
Kajiwara, Naoki;
Iwakura, Yoichiro;
Saito, Hirohisa;
Adachi, Hideo;
Steinman, Lawrence;
Robbins, Robert C.;
Fischbein, Michael P.

Publication type:

Article

Janus-like effects of type I interferon in autoimmune diseases.

Published in:

Immunological Reviews, 2012, v. 248, n. 1, p. 23, doi. 10.1111/j.1600-065X.2012.01131.x

By:

Axtell, Robert C.;
Raman, Chander

Publication type:

Article

T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis.

Published in:

Nature Medicine, 2010, v. 16, n. 4, p. 406, doi. 10.1038/nm.2110

By:

Axtell, Robert C.;
de Jong, Brigit A.;
Boniface, Katia;
van der Voort, Laura F.;
Bhat, Roopa;
De Sarno, Patrizia;
Naves, Rodrigo;
Han, May;
Franklin Zhong;
Castellanos, Jim G.;
Mair, Robert;
Christakos, Athena;
Kolkowitz, Ilan;
Katz, Liat;
Killestein, Joep;
Polman, Chris H.;
de Waal Malefyt, René;
Steinman, Lawrence;
Raman, Chander

Publication type:

Article

Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16625-7

By:

Agasing, Agnieshka M.;
Wu, Qi;
Khatri, Bhuwan;
Borisow, Nadja;
Ruprecht, Klemens;
Brandt, Alexander Ulrich;
Gawde, Saurabh;
Kumar, Gaurav;
Quinn, James L.;
Ko, Rose M.;
Mao-Draayer, Yang;
Lessard, Christopher J.;
Paul, Friedemann;
Axtell, Robert C.

Publication type:

Article

New Frontiers in Multiple Sclerosis Treatment: From Targeting Costimulatory Molecules to Bispecific Antibodies.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 8, p. 3880, doi. 10.3390/ijms26083880

By:

Reidy, Megan;
Khan, Meerah;
Mills, Elizabeth A.;
Wu, Qi;
Garton, Josh;
Draayer, Dean E.;
Zahoor, Insha;
Giri, Shailendra;
Axtell, Robert C.;
Mao-Draayer, Yang

Publication type:

Article

Adrenocorticotropic hormone versus methylprednisolone added to interferon β in patients with multiple sclerosis experiencing breakthrough disease: a randomized, rater-blinded trial.

Published in:

Therapeutic Advances in Neurological Disorders, 2017, v. 10, n. 1, p. 3, doi. 10.1177/1756285616670060

By:

Berkovich, Regina;
Bakshi, Rohit;
Amezcua, Lilyana;
Axtell, Robert C.;
Cen, Steven Y.;
Tauhid, Shahamat;
Neema, Mohit;
Steinman, Lawrence

Publication type:

Article

Works by Axtell, Robert C.

Gaining entry to an uninflamed brain.

The Role of B Cells in Primary Progressive Multiple Sclerosis.

Reversal of Paralysis and Reduced Inflammation from Peripheral Administration of β-Amyloid in T<sub>H</sub>1 and T<sub>H</sub>17 Versions of Experimental Autoimmune Encephalomyelitis.

B-Lymphocyte-Mediated Delayed Cognitive Impairment following Stroke.

Loss of Nrf2 exacerbates the visual deficits and optic neuritis elicited by experimental autoimmune encephalomyelitis.

Myelinspecific Th17 cells induce severe relapsing optic neuritis with irreversible loss of retinal ganglion cells in C57BL/6 mice.

Interferon-β Intensifies Interleukin-23-Driven Pathogenicity of T Helper Cells in Neuroinflammatory Disease.

Erratum: Common variants in P2RY11 are associated with narcolepsy.

Common variants in P2RY11 are associated with narcolepsy.

Depleting tumor-specific Tregs at a single site eradicates disseminated tumors.

Depleting tumor-specific Tregs at a single site eradicates disseminated tumors.

Role of TFH Cells in Promoting T Helper 17-Induced Neuroinflammation.

Dual Role of B Cells in Multiple Sclerosis.

Pertussis Toxin Inhibits Encephalitogenic T-Cell Infiltration and Promotes a B-Cell-Driven Disease during Th17-EAE.

Emerging Role of Follicular T Helper Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis.

Piet Mondrian’s trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011.

Protective effect of an elastase inhibitor in a neuromyelitis optica-like disease driven by a peptide of myelin oligodendroglial glycoprotein.

Defective sphingosine 1-phosphate receptor 1 (S1P<sub>1</sub>) phosphorylation exacerbates T<sub>H</sub>17-mediated autoimmune neuroinflammation.

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain.

Antigen presentation and interferon signatures in B cells driven by localized ablative cancer immunotherapy correlate with extended survival.

IL-17 Contributes to the Development of Chronic Rejection in a Murine Heart Transplant Model.

Janus-like effects of type I interferon in autoimmune diseases.

T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis.

Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica.

New Frontiers in Multiple Sclerosis Treatment: From Targeting Costimulatory Molecules to Bispecific Antibodies.

Adrenocorticotropic hormone versus methylprednisolone added to interferon β in patients with multiple sclerosis experiencing breakthrough disease: a randomized, rater-blinded trial.