Works by Awakawa, Takayoshi
Results: 49
Biosynthesis of unique natural product scaffolds by Fe(II)/αKG-dependent oxygenases.
- Published in:
- Journal of Natural Medicines, 2025, v. 79, n. 2, p. 303, doi. 10.1007/s11418-025-01880-z
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- Article
Structure-function analysis of 2-sulfamoylacetic acid synthase in altemicidin biosynthesis.
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- Journal of Antibiotics, 2025, v. 78, n. 3, p. 149, doi. 10.1038/s41429-024-00798-0
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- Article
Discovery of (±)‐Penindolenes Reveals an Unusual Indole Ring Cleavage Pathway Catalyzed by P450 Monooxygenase.
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- Angewandte Chemie, 2024, v. 136, n. 26, p. 1, doi. 10.1002/ange.202403963
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- Article
Aziridine Formation by a Fe<sup>II</sup>/α‐Ketoglutarate Dependent Oxygenase and 2‐Aminoisobutyrate Biosynthesis in Fungi.
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- Angewandte Chemie, 2021, v. 133, n. 29, p. 15961, doi. 10.1002/ange.202104644
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- Article
Biosynthesis of Biscognienyne B Involving a Cytochrome P450‐Dependent Alkynylation.
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- Angewandte Chemie, 2020, v. 132, n. 32, p. 13633, doi. 10.1002/ange.202004364
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- Article
Biosynthesis of sulfonamide and sulfamate antibiotics in actinomycete.
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- Journal of Industrial Microbiology & Biotechnology, 2021, v. 48, n. 3/4, p. 1, doi. 10.1093/jimb/kuab001
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- Article
Biosynthesis of sulfonamide and sulfamate antibiotics in actinomycete.
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- Journal of Industrial Microbiology & Biotechnology, 2021, p. 1, doi. 10.1093/jimb/kuab001
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- Article
Cover Feature: Involvement of β‐Alkylation Machinery and Two Sets of Ketosynthase‐Chain‐Length Factors in the Biosynthesis of Fogacin Polyketides in Actinoplanes missouriensis (ChemBioChem 8/2019).
- Published in:
- ChemBioChem, 2019, v. 20, n. 8, p. 975, doi. 10.1002/cbic.201900175
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- Article
Involvement of β‐Alkylation Machinery and Two Sets of Ketosynthase‐Chain‐Length Factors in the Biosynthesis of Fogacin Polyketides in Actinoplanes missouriensis.
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- ChemBioChem, 2019, v. 20, n. 8, p. 1039, doi. 10.1002/cbic.201800640
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- Article
Bifunctionality of ActIV as a Cyclase-Thioesterase Revealed by in Vitro Reconstitution of Actinorhodin Biosynthesis in Streptomyces coelicolor A3(2).
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- ChemBioChem, 2017, v. 18, n. 3, p. 316, doi. 10.1002/cbic.201600589
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- Article
Structure-function analysis of carrier protein-dependent 2-sulfamoylacetyl transferase in the biosynthesis of altemicidin.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-55265-z
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- Article
Structural Diversification of Lyngbyatoxin A by Host-Dependent Heterologous Expression of the tleABC Biosynthetic Gene Cluster.
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- ChemBioChem, 2016, v. 17, n. 15, p. 1407, doi. 10.1002/cbic.201600229
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- Article
Salinipyrone and Pacificanone Are Biosynthetic Byproducts of the Rosamicin Polyketide Synthase.
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- ChemBioChem, 2015, v. 16, n. 10, p. 1443, doi. 10.1002/cbic.201500177
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- Article
Three Acyltetronic Acid Derivatives: Noncanonical Cryptic Polyketides from Aspergillus niger Identified by Genome Mining.
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- ChemBioChem, 2014, v. 15, n. 11, p. 1578, doi. 10.1002/cbic.201402172
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- Article
Pyranonigrin E: A PKS-NRPS Hybrid Metabolite from Aspergillus niger Identified by Genome Mining.
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- ChemBioChem, 2013, v. 14, n. 16, p. 2095, doi. 10.1002/cbic.201300430
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- Article
4-Hydroxy-3-methyl-6-(1-methyl-2-oxoalkyl)pyran-2-one Synthesis by a Type III Polyketide Synthase from Rhodospirillum centenum.
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- ChemBioChem, 2013, v. 14, n. 8, p. 1006, doi. 10.1002/cbic.201300066
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- Article
Terretonin Biosynthesis Requires Methylation as Essential Step for Cyclization.
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- ChemBioChem, 2012, v. 13, n. 12, p. 1738, doi. 10.1002/cbic.201200369
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- Article
Characterization of the Biosynthesis Gene Cluster for Alkyl- O-Dihydrogeranyl-Methoxyhydroquinones in Actinoplanes missouriensis.
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- ChemBioChem, 2011, v. 12, n. 3, p. 439, doi. 10.1002/cbic.201000628
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- Article
C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26585-1
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- Publication type:
- Article
Discovery of (±)‐Penindolenes Reveals an Unusual Indole Ring Cleavage Pathway Catalyzed by P450 Monooxygenase.
- Published in:
- Angewandte Chemie International Edition, 2024, v. 63, n. 26, p. 1, doi. 10.1002/anie.202403963
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- Publication type:
- Article
Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02371-w
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- Article
Biosynthesis of helvolic acid and identification of an unusual C-4-demethylation process distinct from sterol biosynthesis.
- Published in:
- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01813-9
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- Article
Manipulation of prenylation reactions by structure-based engineering of bacterial indolactam prenyltransferases.
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- Nature Communications, 2016, v. 7, n. 3, p. 10849, doi. 10.1038/ncomms10849
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- Article
Reconstitution of Polyketide-Derived Meroterpenoid Biosynthetic Pathway in Aspergillus oryzae.
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- Journal of Fungi, 2021, v. 7, n. 6, p. 1, doi. 10.3390/jof7060486
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- Article
Induced biosyntheses of a novel butyrophenone and two aromatic polyketides in the plant pathogen Stagonospora nodorum.
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- Natural Products & Bioprospecting, 2013, v. 3, n. 4, p. 141, doi. 10.1007/s13659-013-0055-2
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- Article
Aminoacyl sulfonamide assembly in SB-203208 biosynthesis.
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- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08093-x
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- Article
Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05877-z
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- Article
Biosynthetic pathway for furanosteroid demethoxyviridin and identification of an unusual pregnane side-chain cleavage.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04298-2
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- Publication type:
- Article
Aziridine Formation by a Fe<sup>II</sup>/α‐Ketoglutarate Dependent Oxygenase and 2‐Aminoisobutyrate Biosynthesis in Fungi.
- Published in:
- Angewandte Chemie International Edition, 2021, v. 60, n. 29, p. 15827, doi. 10.1002/anie.202104644
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- Publication type:
- Article
Biosynthesis of Biscognienyne B Involving a Cytochrome P450‐Dependent Alkynylation.
- Published in:
- Angewandte Chemie International Edition, 2020, v. 59, n. 32, p. 13531, doi. 10.1002/anie.202004364
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- Publication type:
- Article
Molecular Insight into the Mg<sup>2+</sup>‐Dependent Allosteric Control of Indole Prenylation by Aromatic Prenyltransferase AmbP1.
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- Angewandte Chemie International Edition, 2018, v. 57, n. 23, p. 6810, doi. 10.1002/anie.201800855
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- Article
Umezawamides, new bioactive polycyclic tetramate macrolactams isolated from a combined-culture of Umezawaea sp. and mycolic acid-containing bacterium.
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- Journal of Antibiotics, 2018, v. 71, n. 7, p. 653, doi. 10.1038/s41429-018-0040-4
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- Article
Arcyriaflavin E, a new cytotoxic indolocarbazole alkaloid isolated by combined-culture of mycolic acid-containing bacteria and Streptomyces cinnamoneus NBRC 13823.
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- Journal of Antibiotics, 2015, v. 68, n. 5, p. 342, doi. 10.1038/ja.2014.147
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- Article
The International Conference of Natural Product Biosynthesis (ICNPB, 8th US-Japan seminar on the Biosynthesis of Natural Products).
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- Journal of Antibiotics, 2012, v. 65, n. 11, p. 587, doi. 10.1038/ja.2012.74
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- Article
Enzymatic reactions in teleocidin B biosynthesis.
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- Journal of Natural Medicines, 2021, v. 75, n. 3, p. 467, doi. 10.1007/s11418-021-01504-2
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- Publication type:
- Article
Molecular Insight into the Mg<sup>2+</sup>‐Dependent Allosteric Control of Indole Prenylation by Aromatic Prenyltransferase AmbP1.
- Published in:
- Angewandte Chemie, 2018, v. 130, n. 23, p. 6926, doi. 10.1002/ange.201800855
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- Article
Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3.
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- Angewandte Chemie, 2018, v. 130, n. 2, p. 569, doi. 10.1002/ange.201710682
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- Article
Enzymatic C−H Oxidation-Amidation Cascade in the Production of Natural and Unnatural Thiotetronate Antibiotics with Potentiated Bioactivity.
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- Angewandte Chemie, 2017, v. 129, n. 40, p. 12402, doi. 10.1002/ange.201705239
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- Article
Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol Polyketides.
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- Angewandte Chemie, 2017, v. 129, n. 7, p. 1766, doi. 10.1002/ange.201611371
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- Article
Frontispiz: Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol Polyketides.
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- Angewandte Chemie, 2017, v. 129, n. 7, p. n/a, doi. 10.1002/ange.201780761
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- Article
Rational Control of Polyketide Extender Units by Structure-Based Engineering of a Crotonyl-CoA Carboxylase/Reductase in Antimycin Biosynthesis.
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- Angewandte Chemie, 2015, v. 127, n. 45, p. 13664, doi. 10.1002/ange.201506899
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- Article
Multiplexing of Combinatorial Chemistry in Antimycin Biosynthesis: Expansion of Molecular Diversity and Utility.
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- Angewandte Chemie, 2013, v. 125, n. 47, p. 12534, doi. 10.1002/ange.201305569
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- Publication type:
- Article
Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3.
- Published in:
- Angewandte Chemie International Edition, 2018, v. 57, n. 2, p. 560, doi. 10.1002/anie.201710682
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- Publication type:
- Article
Enzymatic C−H Oxidation-Amidation Cascade in the Production of Natural and Unnatural Thiotetronate Antibiotics with Potentiated Bioactivity.
- Published in:
- Angewandte Chemie International Edition, 2017, v. 56, n. 40, p. 12234, doi. 10.1002/anie.201705239
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- Publication type:
- Article
Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol Polyketides.
- Published in:
- Angewandte Chemie International Edition, 2017, v. 56, n. 7, p. 1740, doi. 10.1002/anie.201611371
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- Publication type:
- Article
Frontispiece: Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol Polyketides.
- Published in:
- Angewandte Chemie International Edition, 2017, v. 56, n. 7, p. n/a, doi. 10.1002/anie.201780761
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- Publication type:
- Article
Rational Control of Polyketide Extender Units by Structure-Based Engineering of a Crotonyl-CoA Carboxylase/Reductase in Antimycin Biosynthesis.
- Published in:
- Angewandte Chemie International Edition, 2015, v. 54, n. 45, p. 13462, doi. 10.1002/anie.201506899
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- Publication type:
- Article
Multiplexing of Combinatorial Chemistry in Antimycin Biosynthesis: Expansion of Molecular Diversity and Utility.
- Published in:
- Angewandte Chemie International Edition, 2013, v. 52, n. 47, p. 12308, doi. 10.1002/anie.201305569
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- Publication type:
- Article
Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont.
- Published in:
- Nature Chemical Biology, 2014, v. 10, n. 8, p. 648, doi. 10.1038/nchembio.1573
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- Article