Works by Autio, Anu

Results: 27

Establishing a GMP-compliant manufacturing process and phase-appropriate analytics for early development of a FiCAR T-cell product with a novel CAR spacer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-92736-9

By:

Luostarinen, Annu;
Vuorela, Arja;
Kerkelä, Erja;
Patrikoski, Mimmi;
Kotovuori, Annika;
Koski, Jan;
Ahoniemi, Jonna;
Lähteenmäki, Kaarina;
Lehtisalo, Jenni;
Oja, Terhi;
Paavilainen, Henrik;
Autio, Anu;
Nyman, Marie;
Nikoskelainen, Veera;
Kergourlay, Virginie;
Elbasani, Endrit;
van Veen, Bert;
Thotakura, Anil;
Monzo, Hector;
Ojala, Päivi M.

Publication type:

Article

Exhausted T cells hijacking the cancer-immunity cycle: Assets and liabilities.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1151632

By:

Brunell, Anna E.;
Lahesmaa, Riitta;
Autio, Anu;
Thotakura, Anil K.

Publication type:

Article

Voluntary wheel running reduces tumor growth and increases capillarity in the heart during doxorubicin chemotherapy in a murine model of breast cancer.

Published in:

Frontiers in Physiology, 2024, p. 1, doi. 10.3389/fphys.2024.1347347

By:

Uurasmaa, Tytti-Maria;
Ricardo, Chloé;
Autio, Anu;
Heinonen, Ilkka H. A.;
Rundqvist, Helene;
Anttila, Katja

Publication type:

Article

SIRPα - CD47 axis regulates dendritic cell-T cell interactions and TCR activation during T cell priming in spleen.

Published in:

PLoS ONE, 2022, v. 17, n. 4, p. 1, doi. 10.1371/journal.pone.0266566

By:

Autio, Anu;
Huan Wang;
Velázquez, Francisco;
Newton, Gail;
Parkos, Charles A.;
Engel, Pablo;
Engelbertsen, Daniel;
Lichtman, Andrew H.;
Luscinskas, Francis W.

Publication type:

Article

First-in-Human Study of 68Ga-DOTA-Siglec-9, PET Ligand Targeting Vascular Adhesion Protein 1.

Published in:

Journal of Nuclear Medicine, 2020, v. 61, n. 12, p. 1, doi. 10.2967/jnumed.120.250696

By:

Viitanen, Riikka;
Moisio, Olli;
Lankinen, Petteri;
Xiang-Guo Li;
Mikko Koivumäki;
Suilamo, Sami;
Tolvanen, Tuula;
Taimen, Kirsi;
Mali, Markku;
Ia Kohonen;
Koskivirta, Ilpo;
Oikonen, Vesa;
Virtanen, Helena;
Santalahti, Kristiina;
Autio, Anu;
Saraste, Antti;
Pirilä, Laura;
Nuutila, Pirjo;
Knuuti, Juhani;
Jalkanen, Sirpa

Publication type:

Article

First-in-Human Study of 68Ga-DOTA-Siglec-9, PET Ligand Targeting Vascular Adhesion Protein 1.

Published in:

Journal of Nuclear Medicine, 2020, v. 61, n. 11, p. 1, doi. 10.2967/jnumed.120.250696

By:

Viitanen, Riikka;
Moisio, Olli;
Lankinen, Petteri;
Xiang-Guo Li;
Koivumäki, Mikko;
Suilamo, Sami;
Tolvanen, Tuula;
Taimen, Kirsi;
Mali, Markku;
Kohonen, Ia;
Koskivirta, Ilpo;
Oikonen, Vesa;
Virtanen, Helena;
Santalahti, Kristiina;
Autio, Anu;
Saraste, Antti;
Pirilä, Laura;
Nuutila, Pirjo;
Knuuti, Juhani;
Jalkanen, Sirpa

Publication type:

Article

First-in-Human Study of 68Ga-DOTA-Siglec-9, PET Ligand Targeting Vascular Adhesion Protein 1.

Published in:

Journal of Nuclear Medicine, 2020, v. 61, n. 10, p. 1, doi. 10.2967/jnumed.120.250696

By:

Viitanen, Riikka;
Moisio, Olli;
Lankinen, Petteri;
Xiang-Guo Li;
Koivumäki, Mikko;
Suilamo, Sami;
Tolvanen, Tuula;
Taimen, Kirsi;
Mali, Markku;
Ia Kohonen;
Koskivirta, Ilpo;
Oikonen, Vesa;
Virtanen, Helena;
Santalahti, Kristiina;
Autio, Anu;
Saraste, Antti;
Pirilä, Laura;
Nuutila, Pirjo;
Knuuti, Juhani;
Jalkanen, Sirpa

Publication type:

Article

First-in-Human Study of 68Ga-DOTA-Siglec-9, PET Ligand Targeting Vascular Adhesion Protein 1.

Published in:

Journal of Nuclear Medicine, 2020, v. 61, n. 9, p. 1, doi. 10.2967/jnumed.120.250696

By:

Viitanen, Riikka;
Moisio, Olli;
Lankinen, Petteri;
Xiang-Guo Li;
Koivumäki, Mikko;
Suilamo, Sami;
Tolvanen, Tuula;
Taimen, Kirsi;
Mali, Markku;
Kohonen, Ia;
Koskivirta, Ilpo;
Oikonen, Vesa;
Virtanen, Helena;
Santalahti, Kristiina;
Autio, Anu;
Saraste, Antti;
Pirilä, Laura;
Nuutila, Pirjo;
Knuuti, Juhani;
Jalkanen, Sirpa

Publication type:

Article

68Ga-DOTA-E[c(RGDfK)]2 PET Imaging of SHARPIN-Regulated Integrin Activity in Mice.

Published in:

Journal of Nuclear Medicine, 2019, v. 60, n. 12, p. 1, doi. 10.2967/jnumed.118.222026

By:

Siitonen, Riikka;
Peuhu, Emilia;
Autio, Anu;
Liljenbäck, Heidi;
Mattila, Elina;
Metsälä, Olli;
Käkelä, Meeri;
Saanijoki, Tiina;
Dijkgraaf, Ingrid;
Jalkanen, Sirpa;
Ivaska, Johanna;
Roivainen, Anne

Publication type:

Article

68Ga-DOTA-E[c(RGDfK)]2 PET Imaging of SHARPIN- Regulated Integrin Activity in Mice.

Published in:

Journal of Nuclear Medicine, 2019, v. 60, n. 10, p. 1380, doi. 10.2967/jnumed.118.222026

By:

Siitonen, Riikka;
Peuhu, Emilia;
Autio, Anu;
Liljenbäck, Heidi;
Mattila, Elina;
Metsälä, Olli;
Käkelä, Meeri;
Saanijoki, Tiina;
Dijkgraaf, Ingrid;
Jalkanen, Sirpa;
Ivaska, Johanna;
Roivainen, Anne

Publication type:

Article

Preclinical Evaluation of a Radioiodinated Fully Human Antibody for In Vivo Imaging of Vascular Adhesion Protein-1-Positive Vasculature in Inflammation.

Published in:

Journal of Nuclear Medicine, 2013, v. 54, n. 8, p. 1315, doi. 10.2967/jnumed.113.120295

By:

Autio, Anu;
Vainio, Petri J.;
Suilamo, Sami;
Mali, Antti;
Vainio, Jani;
Saanijoki, Tiina;
Noponen, Tommi;
Ahtinen, Helena;
Luoto, Pauliina;
Teräs, Mika;
Jalkanen, Sirpa;
Roivainen, Anne

Publication type:

Article

The circadian gene Cryptochrome 2 influences stress‐induced brain activity and depressive‐like behavior in mice.

Published in:

Genes, Brain & Behavior, 2021, v. 20, n. 4, p. 1, doi. 10.1111/gbb.12708

By:

Sokolowska, Ewa;
Viitanen, Riikka;
Misiewicz, Zuzanna;
Mennesson, Marie;
Saarnio, Suvi;
Kulesskaya, Natalia;
Kängsep, Sanna;
Liljenbäck, Heidi;
Marjamäki, Päivi;
Autio, Anu;
Callan, Saija‐Anita;
Nuutila, Pirjo;
Roivainen, Anne;
Partonen, Timo;
Hovatta, Iiris

Publication type:

Article

Role of Brown and Beige Adipose Tissues in Seasonal Adaptation in the Raccoon Dog (Nyctereutes procyonoides).

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9623, doi. 10.3390/ijms22179623

By:

Niiranen, Laura;
Mäkelä, Kari A.;
Mutt, Shivaprakash J.;
Viitanen, Riikka;
Kaisanlahti, Anna;
Vicente, David;
Noponen, Tommi;
Autio, Anu;
Roivainen, Anne;
Nuutila, Pirjo;
Saarela, Seppo;
Herzig, Karl-Heinz

Publication type:

Article

Cross-validation of input functions obtained by H₂ 15O PET imaging of rat heart and a blood flow-through detector.

Published in:

2012

By:

Kudomi N;
Sipilä H;
Autio A;
Oikonen V;
Liljenbäck H;
Tarkia M;
Laivola J;
Johansson J;
Teräs M;
Roivainen A;
Kudomi, Nobuyuki;
Sipilä, Hannu;
Autio, Anu;
Oikonen, Vesa;
Liljenbäck, Heidi;
Tarkia, Miikka;
Laivola, Jarno;
Johansson, Jarkko;
Teräs, Mika;
Roivainen, Anne

Publication type:

journal article

Cross-validation of Input Functions Obtained by HO PET Imaging of Rat Heart and a Blood Flow-through Detector.

Published in:

Molecular Imaging & Biology, 2012, v. 14, n. 4, p. 509, doi. 10.1007/s11307-011-0511-5

By:

Kudomi, Nobuyuki;
Sipilä, Hannu;
Autio, Anu;
Oikonen, Vesa;
Liljenbäck, Heidi;
Tarkia, Miikka;
Laivola, Jarno;
Johansson, Jarkko;
Teräs, Mika;
Roivainen, Anne

Publication type:

Article

68Ga-chloride PET reveals human pancreatic adenocarcinoma xenografts in rats--comparison with FDG.

Published in:

2010

By:

Ujula, Tiina;
Salomäki, Satu;
Autio, Anu;
Luoto, Pauliina;
Tolvanen, Tuula;
Lehikoinen, Pertti;
Viljanen, Tapio;
Sipilä, Hannu;
Härkönen, Pirkko;
Roivainen, Anne;
Salomäki, Satu;
Sipilä, Hannu;
Härkönen, Pirkko

Publication type:

journal article

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health.

Published in:

Science Translational Medicine, 2016, v. 8, n. 323, p. 1, doi. 10.1126/scitranslmed.aad0015

By:

Laurila, Pirkka-Pekka;
Soronen, Jarkko;
Kooijman, Sander;
Forsström, Saara;
Boon, Mariëtte R.;
Surakka, Ida;
Kaiharju, Essi;
Coomans, Claudia P.;
Van Den Berg, Sjoerd A. A.;
Autio, Anu;
Sarin, Antti-Pekka;
Kettunen, Johannes;
Tikkanen, Emmi;
Manninen, Tuula;
Metso, Jari;
Silvennoinen, Reija;
Merikanto, Krista;
Ruuth, Maija;
Perttilä, Julia;
Mäkelä, Anne

Publication type:

Article

Exercise training partly ameliorates cardiac dysfunction in mice during doxorubicin treatment of breast cancer.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06108-y

By:

Uurasmaa, Tytti-Maria;
Bourdin, Pauline;
Nammas, Wail;
Latifi, Shiva;
Liljenbäck, Heidi;
Saraste, Antti;
Eskola, Olli;
Rajander, Johan;
Roivainen, Anne;
Rundqvist, Helene;
Autio, Anu;
Heinonen, Ilkka;
Anttila, Katja

Publication type:

Article

PET imaging of inflammation and adenocarcinoma xenografts using vascular adhesion protein 1 targeting peptide Ga-DOTAVAP-P1: comparison with F-FDG.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2010, v. 37, n. 10, p. 1918, doi. 10.1007/s00259-010-1497-y

By:

Autio, Anu;
Ujula, Tiina;
Luoto, Pauliina;
Salomäki, Satu;
Jalkanen, Sirpa;
Roivainen, Anne

Publication type:

Article

Biodistribution and radiation dosimetry of [11C]choline: a comparison between rat and human data.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2010, v. 37, n. 5, p. 874, doi. 10.1007/s00259-009-1346-z

By:

Tolvanen, Tuula;
Yli-Kerttula, Timo;
Ujula, Tiina;
Autio, Anu;
Lehikoinen, Pertti;
Minn, Heikki;
Roivainen, Anne

Publication type:

Article

Increased lymphocyte activation and atherosclerosis in CD47-deficient mice.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46942-x

By:

Engelbertsen, Daniel;
Autio, Anu;
Verwilligen, Robin A. F.;
Depuydt, Marie A. C.;
Newton, Gail;
Rattik, Sara;
Levinsohn, Erik;
Saggu, Gurpanna;
Jarolim, Petr;
Wang, Huan;
Velazquez, Francisco;
Lichtman, Andrew H.;
Luscinskas, Francis W.

Publication type:

Article

Preliminary evaluation of novel 68Ga-DOTAVAP-PEG-P2 peptide targeting vascular adhesion protein-1.

Published in:

Clinical Physiology & Functional Imaging, 2010, v. 30, n. 1, p. 75, doi. 10.1111/j.1475-097X.2009.00907.x

By:

Silvola, Johanna;
Autio, Anu;
Luoto, Pauliina;
Jalkanen, Sirpa;
Roivainen, Anne

Publication type:

Article

68Ga-DOTA-Siglec-9 - a new imaging tool to detect synovitis.

Published in:

Arthritis Research & Therapy, 2015, v. 17, p. 1, doi. 10.1186/s13075-015-0826-8

By:

Virtanen, Helena;
Autio, Anu;
Siitonen, Riikka;
Liljenbäck, Heidi;
Saanijoki, Tiina;
Lankinen, Petteri;
Mäkilä, Jussi;
Käkelä, Meeri;
Teuho, Jarmo;
Savisto, Nina;
Jaakkola, Kimmo;
Jalkanen, Sirpa;
Roivainen, Anne

Publication type:

Article

Erratum to: Absorption, distribution and excretion of intravenously injected Ge/Ga generator eluate in healthy rats, and estimation of human radiation dosimetry.

Published in:

2016

By:

Autio, Anu;
Virtanen, Helena;
Tolvanen, Tuula;
Liljenbäck, Heidi;
Oikonen, Vesa;
Saanijoki, Tiina;
Siitonen, Riikka;
Käkelä, Meeri;
Schüssele, Andrea;
Teräs, Mika;
Roivainen, Anne

Publication type:

Erratum

Absorption, distribution and excretion of intravenously injected Ge/Ga generator eluate in healthy rats, and estimation of human radiation dosimetry.

Published in:

EJNMMI Research, 2015, v. 5, n. 1, p. 1, doi. 10.1186/s13550-015-0117-z

By:

Autio, Anu;
Virtanen, Helena;
Tolvanen, Tuula;
Liljenbäck, Heidi;
Oikonen, Vesa;
Saanijoki, Tiina;
Siitonen, Riikka;
Käkelä, Meeri;
Schüssele, Andrea;
Teräs, Mika;
Roivainen, Anne

Publication type:

Article

VAMMAISPALVELUN ASIAKASSUUNNITELMAT ASIAKASOSALLISUUDEN RAKENTAJINA.

Published in:

Janus, 2015, v. 23, n. 2, p. 231

By:

Autio, Anu;
Nurmi-Koikkalainen, Päivi

Publication type:

Article

Feasibility of experimental BT4C glioma models for somatostatin receptor 2-targeted therapies.

Published in:

Acta Oncologica, 2014, v. 53, n. 8, p. 1125, doi. 10.3109/0284186X.2014.925577

By:

Kiviniemi, Aida;
Gardberg, Maria;
Autio, Anu;
Li, Xiang-Guo;
Heuser, Vanina D.;
Liljenbäck, Heidi;
Käkel, Meeri;
Sipil, Henri;
Kurkipuro, Jere;
Ylä-Herttuala, Seppo;
Knuuti, Juhani;
Minn, Heikki;
Roivainen, Anne

Publication type:

Article

Works by Autio, Anu

Establishing a GMP-compliant manufacturing process and phase-appropriate analytics for early development of a FiCAR T-cell product with a novel CAR spacer.

Exhausted T cells hijacking the cancer-immunity cycle: Assets and liabilities.

Voluntary wheel running reduces tumor growth and increases capillarity in the heart during doxorubicin chemotherapy in a murine model of breast cancer.

SIRPα - CD47 axis regulates dendritic cell-T cell interactions and TCR activation during T cell priming in spleen.

First-in-Human Study of <sup>68</sup>Ga-DOTA-Siglec-9, PET Ligand Targeting Vascular Adhesion Protein 1.

First-in-Human Study of <sup>68</sup>Ga-DOTA-Siglec-9, PET Ligand Targeting Vascular Adhesion Protein 1.

First-in-Human Study of <sup>68</sup>Ga-DOTA-Siglec-9, PET Ligand Targeting Vascular Adhesion Protein 1.

First-in-Human Study of <sup> 68</sup>Ga-DOTA-Siglec-9, PET Ligand Targeting Vascular Adhesion Protein 1.

<sup>68</sup>Ga-DOTA-E[c(RGDfK)]<sub>2</sub> PET Imaging of SHARPIN-Regulated Integrin Activity in Mice.

<sup>68</sup>Ga-DOTA-E[c(RGDfK)]<sub>2</sub> PET Imaging of SHARPIN- Regulated Integrin Activity in Mice.

Preclinical Evaluation of a Radioiodinated Fully Human Antibody for In Vivo Imaging of Vascular Adhesion Protein-1-Positive Vasculature in Inflammation.

The circadian gene Cryptochrome 2 influences stress‐induced brain activity and depressive‐like behavior in mice.

Role of Brown and Beige Adipose Tissues in Seasonal Adaptation in the Raccoon Dog (Nyctereutes procyonoides).

Cross-validation of input functions obtained by H₂ 15O PET imaging of rat heart and a blood flow-through detector.

Cross-validation of Input Functions Obtained by HO PET Imaging of Rat Heart and a Blood Flow-through Detector.

68Ga-chloride PET reveals human pancreatic adenocarcinoma xenografts in rats--comparison with FDG.

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health.

Exercise training partly ameliorates cardiac dysfunction in mice during doxorubicin treatment of breast cancer.

PET imaging of inflammation and adenocarcinoma xenografts using vascular adhesion protein 1 targeting peptide Ga-DOTAVAP-P1: comparison with F-FDG.

Biodistribution and radiation dosimetry of [<sup>11</sup>C]choline: a comparison between rat and human data.

Increased lymphocyte activation and atherosclerosis in CD47-deficient mice.

Preliminary evaluation of novel <sup>68</sup>Ga-DOTAVAP-PEG-P2 peptide targeting vascular adhesion protein-1.

<sup>68</sup>Ga-DOTA-Siglec-9 - a new imaging tool to detect synovitis.

Erratum to: Absorption, distribution and excretion of intravenously injected Ge/Ga generator eluate in healthy rats, and estimation of human radiation dosimetry.

Absorption, distribution and excretion of intravenously injected Ge/Ga generator eluate in healthy rats, and estimation of human radiation dosimetry.

VAMMAISPALVELUN ASIAKASSUUNNITELMAT ASIAKASOSALLISUUDEN RAKENTAJINA.

Feasibility of experimental BT4C glioma models for somatostatin receptor 2-targeted therapies.