Works matching AU Attie, Alan D.

Results: 68

INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants.

Published in:

Genome Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s13059-021-02450-8

By:

Dong, Chenyang;
Simonett, Shane P.;
Shin, Sunyoung;
Stapleton, Donnie S.;
Schueler, Kathryn L.;
Churchill, Gary A.;
Lu, Leina;
Liu, Xiaoxiao;
Jin, Fulai;
Li, Yan;
Attie, Alan D.;
Keller, Mark P.;
Keleş, Sündüz

Publication type:

Article

Getting biological about the genetics of diabetes.

Published in:

2010

By:

Newgard, Christopher B.;
Attie, Alan D.

Publication type:

Opinion

High-maintenance proteins and hypertriglyceridemia.

Published in:

Nature Genetics, 2007, v. 39, n. 12, p. 1424, doi. 10.1038/ng1207-1424

By:

Attie, Alan D.

Publication type:

Article

Positional cloning of Sorcs1, a type 2 diabetes quantitative trait locus.

Published in:

Nature Genetics, 2006, v. 38, n. 6, p. 688, doi. 10.1038/ng1796

By:

Clee, Susanne M.;
Yandell, Brian S.;
Schueler, Kathryn M.;
Rabaglia, Mary E.;
Richards, Oliver C.;
Raines, Summer M.;
Kabara, Edward A.;
Klass, Daniel M.;
Mui, Eric T.-K.;
Stapleton, Donald S.;
Gray-Keller, Mark P.;
Young, Matthew B.;
Stoehr, Jonathan P.;
Hong Lan;
Boronenkov, Igor;
Raess, Philipp W.;
Flowers, Matthew T.;
Attie, Alan D.

Publication type:

Article

The Collaborative Cross, a community resource for the genetic analysis of complex traits.

Published in:

2004

By:

Churchill, Gary A;
Airey, David C;
Allayee, Hooman;
Angel, Joe M;
Attie, Alan D;
Beatty, Jackson;
Beavis, William D;
Belknap, John K;
Bennett, Beth;
Berrettini, Wade;
Bleich, Andre;
Bogue, Molly;
Broman, Karl W;
Buck, Kari J;
Buckler, Ed;
Burmeister, Margit;
Chesler, Elissa J;
Cheverud, James M;
Clapcote, Steven;
Cook, Melloni N

Publication type:

Opinion

PGC-1a at the crossroads of type 2 diabetes.

Published in:

Nature Genetics, 2003, v. 34, n. 3, p. 244, doi. 10.1038/ng0703-244

By:

Attie, Alan D;
Kendziorski, Christina M

Publication type:

Article

Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation.

Published in:

BMC Genomics, 2010, v. 11, p. 473, doi. 10.1186/1471-2164-11-473

By:

Babak, Tomas;
Garrett-Engele, Philip;
Armour, Christopher D.;
Raymond, Christopher K.;
Keller, Mark P.;
Chen, Ronghua;
Rohl, Carol A.;
Johnson, Jason M.;
Attie, Alan D.;
Fraser, Hunter B.;
Schadt, Eric E.

Publication type:

Article

Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes.

Published in:

FASEB Journal, 2008, v. 22, n. 10, p. 3581, doi. 10.1096/fj.08-111690

By:

Junqin Chen;
Hui, Simon T.;
Couto, Francesca M.;
Mungrue, Imran N.;
Davis, Dawn B.;
Attie, Alan D.;
Lusis, Aldons J.;
Davis, Roger A.;
Shalev, Anath

Publication type:

Article

Distinguishing covariation from causation in diabetes: a lesson from the protein disulfide isomerase mRNA abundance trait.

Published in:

2004

By:

Lan, Hong;
Rabaglia, Mary E;
Schueler, Kathryn L;
Mata, Christine;
Yandell, Brian S;
Attie, Alan D

Publication type:

journal article

Identification of major quantitative trait loci controlling body weight variation in ob/ob mice.

Published in:

2004

By:

Stoehr, Jonathan P.;
Clee, Susanne M.;
Lan, Hong;
Boronenkov, Igor V.;
Schueler, Kathryn L.;
Byers, Jessica E.;
Yandell, Brian S.;
Attie, Alan D.

Publication type:

journal article

Distinguishing Covariation From Causation in Diabetes.

Published in:

Diabetes, 2004, v. 53, n. 1, p. 240, doi. 10.2337/diabetes.53.1.240

By:

Lan, Hong;
Rabaglia, Mary E.;
Schueler, Kathryn L.;
Mata, Christine;
Yandell, Brian S.;
Attie, Alan D.

Publication type:

Article

Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility.

Published in:

2003

By:

Lan, Hong;
Rabaglia, Mary E.;
Stoehr, Jonathan P.;
Nadler, Samuel T.;
Schueler, Kathryn L.;
Zou, Fei;
Yandell, Brian S.;
Attie, Alan D.

Publication type:

journal article

Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci.

Published in:

2000

By:

Stoehr, Jonathan P.;
Nadler, Samuel T.;
Schueler, Kathryn L.;
Rabaglia, Mary E.;
Yandell, Brian S.;
Metz, Stewart A.;
Attie, Alan D.;
Stoehr, J P;
Nadler, S T;
Schueler, K L;
Rabaglia, M E;
Yandell, B S;
Metz, S A;
Attie, A D

Publication type:

journal article

Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36269-7

By:

Yu, Qing;
Liu, Xinyue;
Keller, Mark P.;
Navarrete-Perea, Jose;
Zhang, Tian;
Fu, Sipei;
Vaites, Laura P.;
Shuken, Steven R.;
Schmid, Ernst;
Keele, Gregory R.;
Li, Jiaming;
Huttlin, Edward L.;
Rashan, Edrees H.;
Simcox, Judith;
Churchill, Gary A.;
Schweppe, Devin K.;
Attie, Alan D.;
Paulo, Joao A.;
Gygi, Steven P.

Publication type:

Article

Protein Sortin g Motifs in the Cytoplasmic Tail of SorCSl Control Generation of Alzheimer's Amyloid-ß Peptide.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 16, p. 7099, doi. 10.1523/JNEUROSCI.5270-12.2013

By:

Lane, Rachel F.;
Steele, John W.;
Dongming Cai;
Ehrlich, Michelle E.;
Attie, Alan D.;
Gandy, Sam

Publication type:

Article

Zinc, insulin, and the liver: a ménage à trois.

Published in:

2013

By:

O'Halloran, Thomas V.;
Kebede, Melkam;
Philips, Steven J.;
Attie, Alan D.

Publication type:

Opinion

Defending science education against intelligent design: a call to action.

Published in:

2006

By:

Attie, Alan D.;
Sober, Elliot;
Numbers, Ronald L.;
Amasino, Richard M.;
Cox, Beth;
Berceau, Terese;
Powell, Thomas;
Cox, Michael M.

Publication type:

journal article

The Republican war on science.

Published in:

2006

By:

Attie, Alan D.

Publication type:

Book Review

Genetic Drivers of Pancreatic Islet Function.

Published in:

Genetics, 2018, v. 209, n. 1, p. 335, doi. 10.1534/genetics.118.300864

By:

Keller, Mark P.;
Gatti, Daniel M.;
Schueler, Kathryn L.;
Rabaglia, Mary E.;
Stapleton, Donnie S.;
Simecek, Petr;
Vincent, Matthew;
Allen, Sadie;
Broman, Aimee Teo;
Bacher, Rhonda;
Kendziorski, Christina;
Broman, Karl W.;
Yandell, Brian S.;
Churchill, Gary A.;
Attie, Alan D.

Publication type:

Article

Statistical Methods for Latent Class Quantitative Trait Loci Mapping.

Published in:

Genetics, 2017, v. 206, n. 3, p. 1309, doi. 10.1534/genetics.117.203885

By:

Shuyun Ye;
Bacher, Rhonda;
Keller, Mark P.;
Attie, Alan D.;
Kendziorski, Christina

Publication type:

Article

The Dissection of Expression Quantitative Trait Locus Hotspots.

Published in:

Genetics, 2016, v. 202, n. 4, p. 1563, doi. 10.1534/genetics.115.183624

By:

Tian, Jianan;
Keller, Mark P.;
Teo Broman, Aimee;
Kendziorski, Christina;
Yandell, Brian S.;
Attie, Alan D.;
Broman, Karl W.

Publication type:

Article

Genetic Architectures of Quantitative Variation in RNA Editing Pathways.

Published in:

Genetics, 2016, v. 202, n. 2, p. 787, doi. 10.1534/genetics.115.179481

By:

Tongjun Gu;
Gatti, Daniel M.;
Srivastava, Anuj;
Snyder, Elizabeth M.;
Raghupathy, Narayanan;
Simecek, Petr;
Svenson, Karen L.;
Dotu, Ivan;
Chuang, Jeffrey H.;
Keller, Mark P.;
Attie, Alan D.;
Braun, Robert E.;
Churchill, Gary A.

Publication type:

Article

Identification of the Bile Acid Transporter Slco1a6 as a Candidate Gene That Broadly Affects Gene Expression in Mouse Pancreatic Islets.

Published in:

Genetics, 2015, v. 201, n. 3, p. 1253, doi. 10.1534/genetics.115.179432

By:

Tian, Jianan;
Keller, Mark P.;
Oler, Angie T.;
Rabaglia, Mary E.;
Schueler, Kathryn L.;
Stapleton, Donald S.;
Broman, Aimee Teo;
Zhao, Wen;
Kendziorski, Christina;
Yandell, Brian S.;
Hagenbuch, Bruno;
Broman, Karl W.;
Attie, Alan D.

Publication type:

Article

RNA-Seq Alignment to Individualized Genomes Improves Transcript Abundance Estimates in Multiparent Populations.

Published in:

Genetics, 2014, v. 198, n. 1, p. 59, doi. 10.1534/genetics.114.165886

By:

Munger, Steven C.;
Raghupathy, Narayanan;
Kwangbom Choi;
Simons, Allen K.;
Gatti, Daniel M.;
Hinerfeld, Douglas A.;
Svenson, Karen L.;
Keller, Mark P.;
Attie, Alan D.;
Hibbs, Matthew A.;
Graber, Joel H.;
Chesler, Elissa J.;
Churchill, Gary A.

Publication type:

Article

Modeling Causality for Pairs of Phenotypes in System Genetics.

Published in:

Genetics, 2013, v. 193, n. 3, p. 1003, doi. 10.1534/genetics.112.147124

By:

Neto, Elias Chaibub;
Broman, Aimee T.;
Keller, Mark P.;
Attie, Alan D.;
Bin Zhang;
Zhu, Jun;
Yandell, Brian S.

Publication type:

Article

Quantile-Based Permutation Thresholds for Quantitative Trait Loci Hotspots.

Published in:

Genetics, 2012, v. 191, n. 4, p. 1355, doi. 10.1534/genetics.112.139451

By:

Neto, Elias Chaibub;
Keller, Mark P.;
Broman, Andrew F.;
Attie, Alan D.;
Jansen, Ritsert C.;
Broman, Karl W.;
Yandell, Brian S.

Publication type:

Article

Genome Scans for Transmission Ratio Distortion Regions in Mice.

Published in:

Genetics, 2012, v. 191, n. 1, p. 247, doi. 10.1534/genetics.111.135988

By:

Casellas, Joaquim;
Gularte, Rodrigo J.;
Farber, Charles R.;
Varona, Luis;
Mehrabian, Margarete;
Schadt, Eric E.;
Lusis, Aldon J.;
Attie, Alan D.;
Yandell, Brian S.;
Medrano, Juan F.

Publication type:

Article

A Model Selection Approach for Expression Quantitative Trait Loci (eQTL) Mapping.

Published in:

Genetics, 2011, v. 187, n. 2, p. 611, doi. 10.1534/genetics.110.122796

By:

Ping Wang;
Dawson, John A.;
Keller, Mark P.;
Yandell, Brian S.;
Thornberry, Nancy A.;
Zhang, Bei B.;
I-Ming Wang;
Schadt, Eric E.;
Attie, Alan D.;
Kendziorski, C.

Publication type:

Article

Inferring Causal Phenotype Networks From Segregating Populations.

Published in:

Genetics, 2008, v. 179, n. 2, p. 1089, doi. 10.1534/genetics.107.085167

By:

Neto, Elias Chaibub;
Ferrara, Christine T.;
Attie, Alan D.;
Yandell, Brian S.

Publication type:

Article

Selective Phenotyping for Increased Efficiency in Genetic Mapping Studies.

Published in:

Genetics, 2004, v. 168, n. 4, p. 2285, doi. 10.1534/genetics.104.027524

By:

Chunfang Jin;
Hong Lan;
Attie, Alan D.;
Churchill, Gary A.;
Bulutuglo, Dursun;
Yandell, Brian S.

Publication type:

Article

Dimension Reduction for Mapping mRNA Abundance as Quantitative Traits.

Published in:

Genetics, 2003, v. 164, n. 4, p. 1607, doi. 10.1093/genetics/164.4.1607

By:

Hong Lan;
Stoehr, Jonathan P.;
Nadler, Samuel T.;
Schueler, Kathryn L.;
Yandell, Brian S.;
Attie, Alan D.

Publication type:

Article

Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer's APP/PSEN1 mice by gene targeting of diabetes/Alzheimer's-related Sorcs1.

Published in:

Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0282-y

By:

Knight, Elysse M.;
Ruiz, Henry H.;
Soong Ho Kim;
Harte, Jessica C.;
Hsieh, Wilson;
Glabe, Charles;
Klein, William L.;
Attie, Alan D.;
Buettner, Christoph;
Ehrlich, Michelle E.;
Gandy, Sam

Publication type:

Article

Systems genetics uncovers associations among host amylase locus, gut microbiome, and metabolic traits in mice.

Published in:

Microbiome, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40168-025-02093-y

By:

Zhang, Qijun;
Hutchison, Evan R.;
Pan, Calvin;
Warren, Matthew F.;
Keller, Mark P.;
Attie, Alan D.;
Lusis, Aldons J.;
Rey, Federico E.

Publication type:

Article

Diabetes-linked SORCS1, a gamma-secretase substrate and regulator of Alzheimer APP metabolism, forms complexes with multiple Alzheimer-linked proteins (APP, PS1, BACE, VPS35, and SORLA)

Published in:

2010

By:

Lane, Rachel F.;
Raines, Summer M.;
Levey, Alan;
Lah, James J.;
Small, Scott A.;
Tanzi, Rudolph E.;
Attie, Alan D.;
Gandy, Samuel E.

Publication type:

Abstract

Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 16, p. 4467, doi. 10.1128/MCB.00192-09

By:

Halberg, Nils;
Khan, Tayeba;
Trujillo, Maria E.;
Wernstedt-Asterholm, Ingrid;
Attie, Alan D.;
Sherwani, Shariq;
Wang, Zhao V.;
Landskroner-Eiger, Shira;
Dineen, Sean;
Magalang, Ulysses J.;
Brekken, Rolf A.;
Scherer, Philipp E.

Publication type:

Article

D2H2: diabetes data and hypothesis hub.

Published in:

Bioinformatics Advances, 2023, v. 3, n. 1, p. 1, doi. 10.1093/bioadv/vbad178

By:

Marino, Giacomo B;
Ahmed, Nasheath;
Xie, Zhuorui;
Jagodnik, Kathleen M;
Han, Jason;
Clarke, Daniel J B;
Lachmann, Alexander;
Keller, Mark P;
Attie, Alan D;
Ma'ayan, Avi

Publication type:

Article

Metabolic syndrome: from epidemiology to systems biology.

Published in:

2008

By:

Lusis, Aldons J.;
Attie, Alan D.;
Reue, Karen

Publication type:

journal article

Histone chaperone ASF1B promotes human β -cell proliferation via recruitment of histone H3.3.

Published in:

Cell Cycle, 2016, v. 15, n. 23, p. 3191, doi. 10.1080/15384101.2016.1241914

By:

Paul, Pradyut K.;
Rabaglia, Mary E.;
Wang, Chen-Yu;
Stapleton, Donald S.;
Leng, Ning;
Kendziorski, Christina;
Lewis, Peter W.;
Keller, Mark P.;
Attie, Alan D.

Publication type:

Article

Gene loci associated with insulin secretion in islets from non-diabetic mice.

Published in:

2019

By:

Keller, Mark P.;
Rabaglia, Mary E.;
Schueler, Kathryn L.;
Stapleton, Donnie S.;
Gatti, Daniel M.;
Vincent, Matthew;
Mitok, Kelly A.;
Ziyue Wang;
Takanao Ishimura;
Simonett, Shane P.;
Emfinger, Christopher H.;
Das, Rahul;
Beck, Tim;
Kendziorski, Christina;
Broman, Karl W.;
Yandell, Brian S.;
Churchill, Gary A.;
Attie, Alan D.;
Wang, Ziyue;
Ishimura, Takanao

Publication type:

journal article

Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity.

Published in:

2018

By:

Risheng Ye;
Gordillo, Ruth;
Mengle Shao;
Toshiharu Onodera;
Zhe Chen;
Shiuhwei Chen;
Xiaoli Lin;
SoRelle, Jeffrey A.;
Xiaohong Li;
Miao Tang;
Keller, Mark P.;
Kuliawat, Regina;
Attie, Alan D.;
Gupta, Rana K.;
Holland, William L.;
Beutler, Bruce;
Herz, Joachim;
Scherer, Philipp E.;
Ye, Risheng;
Shao, Mengle

Publication type:

journal article

How do reducing equivalents increase insulin secretion?

Published in:

2015

By:

Attie, Alan D.

Publication type:

journal article

BAI AP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells.

Published in:

Journal of Cell Biology, 2017, v. 216, n. 7, p. 2151, doi. 10.1083/jcb.201702099

By:

Xingmin Zhang;
Shan Jiang;
Mitok, Kelly A.;
Lingjun Li;
Attie, Alan D.;
Martin, Thomas F. J.

Publication type:

Article

The Cellular Trafficking of the Secretory Proprotein Convertase PCSK9 and Its Dependence on the LDLR.

Published in:

2007

By:

Nassoury, Nasha;
Blasiole, Daniel A.;
Oler, Angie Tebon;
Benjannet, Suzanne;
Hamelin, Josée;
Poupon, Vivianne;
McPherson, Peter S.;
Attie, Alan D.;
Prat, Annik;
Seidah, Nabil G.

Publication type:

Correction Notice

The Cellular Trafficking of the Secretory Proprotein Convertase PCSK9 and Its Dependence on the LDLR.

Published in:

Traffic, 2007, v. 8, n. 6, p. 718, doi. 10.1111/j.1600-0854.2007.00562.x

By:

Nassoury, Nasha;
Blasiole, Daniel A.;
Tebon Oler, Angie;
Benjannet, Suzanne;
Hamelin, Josée;
Poupon, Vivianne;
McPherson, Peter S.;
Attie, Alan D.;
Prat, Annik;
Seidah, Nabil G.

Publication type:

Article

Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-11047-6

By:

Niemi, Natalie M.;
Wilson, Gary M.;
Overmyer, Katherine A.;
Vögtle, F.-Nora;
Myketin, Lisa;
Lohman, Danielle C.;
Schueler, Kathryn L.;
Attie, Alan D.;
Meisinger, Chris;
Coon, Joshua J.;
Pagliarini, David J.

Publication type:

Article

Genetic Analysis of Obesity-Induced Diabetic Nephropathy in BTBR Mice.

Published in:

Diabetes, 2024, v. 73, n. 2, p. 312, doi. 10.2337/db23-0444

By:

Keller, Mark P.;
O’Connor, Chris;
Bitzer, Markus;
Schueler, Kathryn L.;
Stapleton, Donald S.;
Emfinger, Christopher H.;
Broman, Aimee Teo;
Hodgin, Jeffrey B.;
Attie, Alan D.

Publication type:

Article

An Enhancer Within Abcb11 Regulates G6pc2 in C57BL/6 Mouse Pancreatic Islets.

Published in:

Diabetes, 2023, v. 72, n. 11, p. 1621, doi. 10.2337/db23-0215

By:

Keller, Mark P.;
Hawes, Emily M.;
Schueler, Kathryn L.;
Stapleton, Donnie S.;
Mitok, Kelly A.;
Simonett, Shane P.;
Oeser, James K.;
Sampson, Leesa L.;
Attie, Alan D.;
Magnuson, Mark A.;
O'Brien, Richard M.

Publication type:

Article

Downregulation of Carnitine Acyl-Carnitine Translocase by miRNAs 132 and 212 Amplifies Glucose-Stimulated Insulin Secretion.

Published in:

Diabetes, 2014, v. 63, n. 11, p. 3805, doi. 10.2337/db13-1677

By:

Soni, Mufaddal S.;
Rabaglia, Mary E.;
Bhatnagar, Sushant;
Jin Shang;
Ilkayeva, Olga;
Mynatt, Randall;
Yun-Ping Zhou;
Schadt, Eric E.;
Thornberry, Nancy A.;
Muoio, Deborah M.;
Keller, Mark P.;
Attie, Alan D.

Publication type:

Article

Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion.

Published in:

2013

By:

Kimple, Michelle E;
Keller, Mark P;
Rabaglia, Mary R;
Pasker, Renee L;
Neuman, Joshua C;
Truchan, Nathan A;
Brar, Harpreet K;
Attie, Alan D

Publication type:

journal article

Prostaglandin E<sub>2</sub> Receptor, EP3, Is Induced in Diabetic Islets and Negatively Regulates Glucose- and Hormone-Stimulated Insulin Secretion.

Published in:

Diabetes, 2013, v. 62, n. 6, p. 1904, doi. 10.2337/db12-0769

By:

Kimple, Michelle E.;
Keller, Mark P.;
Rabaglia, Mary R.;
Pasker, Renee L.;
Neuman, Joshua C.;
Truchan, Nathan A.;
Brar, Harpreet K.;
Attie, Alan D.

Publication type:

Article