Works by Asthana, Shailendra

Results: 40

A pH-dependent direct sulfhydrylation pathway is required for the pathogenesis of Mycobacterium tuberculosis.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08051-6

By:

Nain, Vaibhav Kumar;
Barik, Vishawjeet;
Pandey, Manitosh;
Pareek, Mohit;
Sharma, Taruna;
Pal, Rahul;
Tyagi, Shaifali;
Bajpai, Manish;
Dwivedi, Prabhanjan;
Panda, Bhishma Narayan;
Kumar, Yashwant;
Asthana, Shailendra;
Pandey, Amit Kumar

Publication type:

Article

LOXL2 in non‐alcoholic Steatohepatitis (NASH): Insights into fibrosis pathogenesis and therapeutic potential.

Published in:

Liver International Communications, 2024, v. 5, n. 1/2, p. 1, doi. 10.1002/lci2.85

By:

Immanuel, Joys Rachel;
Kumar, Rajnish;
Agrahari, Ashish Kumar;
Asthana, Shailendra

Publication type:

Article

Wuhan to World: The COVID-19 Pandemic.

Published in:

Frontiers in Cellular & Infection Microbiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fcimb.2021.596201

By:

Kumar, Ashok;
Singh, Rita;
Kaur, Jaskaran;
Pandey, Sweta;
Sharma, Vinita;
Thakur, Lovnish;
Sati, Sangeeta;
Mani, Shailendra;
Asthana, Shailendra;
Sharma, Tarun Kumar;
Chaudhuri, Susmita;
Bhattacharyya, Sankar;
Kumar, Niraj

Publication type:

Article

Template Entrance Channel as Possible Allosteric Inhibition and Resistance Site for Quinolines Tricyclic Derivatives in RNA Dependent RNA Polymerase of Bovine Viral Diarrhea Virus.

Published in:

Pharmaceuticals (14248247), 2023, v. 16, n. 3, p. 376, doi. 10.3390/ph16030376

By:

Srivastava, Mitul;
Mittal, Lovika;
Sarmadhikari, Debapriyo;
Singh, Vijay Kumar;
Fais, Antonella;
Kumar, Amit;
Asthana, Shailendra

Publication type:

Article

Trypanosomatid DRBD9s are likely to be eIF4B orthologues: keIF4Bs in trypanosomatids: Anica Dadwal et al.

Published in:

Journal of Biosciences, 2025, v. 50, n. 1, p. 1, doi. 10.1007/s12038-024-00480-5

By:

Dadwal, Anica;
Sharma, Shilpa;
Asthana, Shailendra;
Das, Supratik

Publication type:

Article

Intradermal Immunization of Soluble Influenza HA Derived from a Lethal Virus Induces High Magnitude and Breadth of Antibody Responses and Provides Complete Protection In Vivo.

Published in:

Vaccines, 2023, v. 11, n. 4, p. 780, doi. 10.3390/vaccines11040780

By:

Raj, Sneha;
Vishwakarma, Preeti;
Saxena, Shikha;
Kumar, Varun;
Khatri, Ritika;
Kumar, Amit;
Singh, Mrityunjay;
Mishra, Surbhi;
Asthana, Shailendra;
Ahmed, Shubbir;
Samal, Sweety

Publication type:

Article

Protein kinase C-mediated sodium glucose transporter 1 activation in precondition-induced cardioprotection.

Published in:

Drug Design, Development & Therapy, 2016, v. 10, p. 2929, doi. 10.2147/DDDT.S105482

By:

Kanwal, Abhinav;
Kasetti, Sujatha;
Putcha, Uday Kumar;
Asthana, Shailendra;
Banerjee, Sanjay K.

Publication type:

Article

Golden Syrian hamster as a model to study cardiovascular complications associated with SARS-CoV-2 infection.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.73522

By:

Rizvi, Zaigham Abbas;
Dalal, Rajdeep;
Sadhu, Srikanth;
Binayke, Akshay;
Dandotiya, Jyotsna;
Kumar, Yashwant;
Shrivastava, Tripti;
Gupta, Sonu Kumar;
Aggarwal, Suruchi;
Tripathy, Manas Ranjan;
Rathore, Deepak Kumar;
Yadav, Amit Kumar;
Medigeshi, Guruprasad R.;
Pandey, Amit Kumar;
Samal, Sweety;
Asthana, Shailendra;
Awasthi, Amit

Publication type:

Article

Characterization and immunogenicity assessment of MERS-CoV pre-fusion spike trimeric oligomers as vaccine immunogen.

Published in:

Human Vaccines & Immunotherapeutics, 2024, v. 20, n. 1, p. 1, doi. 10.1080/21645515.2024.2351664

By:

Ahuja, Rahul;
Vishwakarma, Preeti;
Raj, Sneha;
Kumar, Varun;
Khatri, Ritika;
Lohiya, Bharat;
Saxena, Shikha;
Kaur, Gurleen;
Singh, Gagandeep;
Asthana, Shailendra;
Ahmed, Shubbir;
Samal, Sweety

Publication type:

Article

Characterizing (un)binding mechanism of USP7 inhibitors to unravel the cause of enhanced binding potencies at allosteric checkpoint.

Published in:

Protein Science: A Publication of the Protein Society, 2022, v. 31, n. 9, p. 1, doi. 10.1002/pro.4398

By:

Srivastava, Mitul;
Mittal, Lovika;
Kumari, Anita;
Agrahari, Ashish Kumar;
Singh, Mrityunjay;
Mathur, Rajani;
Asthana, Shailendra

Publication type:

Article

Conformational dynamics of a nicotinic receptor neurotransmitter site.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.92418

By:

Singh, Mrityunjay;
Indurthi, Dinesh C.;
Mittal, Lovika;
Auerbach, Anthony;
Asthana, Shailendra

Publication type:

Article

Common genetic variants associated with Parkinson's disease display widespread signature of epigenetic plasticity.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-54865-w

By:

Sharma, Amit;
Osato, Naoki;
Liu, Hongde;
Asthana, Shailendra;
Dakal, Tikam Chand;
Ambrosini, Giovanna;
Bucher, Philipp;
Schmitt, Ina;
Wüllner, Ullrich

Publication type:

Article

7D, a small molecule inhibits dengue infection by increasing interferons and neutralizing-antibodies via CXCL4:CXCR3:p38:IRF3 and Sirt1:STAT3 axes respectively.

Published in:

EMBO Molecular Medicine, 2024, v. 16, n. 10, p. 2376, doi. 10.1038/s44321-024-00137-8

By:

Gaur, Kishan Kumar;
Asuru, Tejeswara Rao;
Srivastava, Mitul;
Singh, Nitu;
Purushotham, Nikil;
Poojary, Boja;
Das, Bhabatosh;
Bhattacharyya, Sankar;
Asthana, Shailendra;
Guchhait, Prasenjit

Publication type:

Article

A Preliminary Analysis of Recent SARS CoV-2 Variant Surveillance, in Relation to Past COVID-19 History and Vaccination Strategies.

Published in:

Indian Journal of Chest Diseases & Allied Sciences, 2025, v. 67, n. 1, p. 47, doi. 10.5005/jp-journals-11007-0130.27

By:

N., Revathy;
A., Surendranath;
Mittal, Saurabh;
Brijwal, Megha;
Choudhary, Aashish;
Bhattacharyya, Sankar;
Asthana, Shailendra;
Narayan, Jitendra;
Pandey, Rajesh;
Agrawal, Anurag;
Mohan, Anant

Publication type:

Article

Identification and characterization of in vitro and in vivo fidarestat metabolites: Toxicity and efficacy evaluation of metabolites.

Published in:

Journal of Mass Spectrometry, 2021, v. 56, n. 2, p. 1, doi. 10.1002/jms.4694

By:

Borkar, Roshan M.;
Gajji, Shankar;
Mohammed, Soheb A.;
Srivastava, Mithul;
Reddy, Velma Ganga;
Jala, Aishwarya;
Asthana, Shailendra;
Kamal, Ahmed;
Banerjee, Sanjay K.;
Ragampeta, Srinivas

Publication type:

Article

Withaferin A inhibits Chikungunya virus nsP2 protease and shows antiviral activity in the cell culture and mouse model of virus infection.

Published in:

PLoS Pathogens, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.ppat.1012816

By:

Sharma, Kiran Bala;
Subramani, Chandru;
Ganesh, Khashpatika;
Sharma, Anshula;
Basu, Brohmomoy;
Balyan, Shivani;
Sharma, Ghanshyam;
KA, Shouri;
Deb, Arundhati;
Srivastava, Mitul;
Chugh, Saurabh;
Sehrawat, Sapna;
Bharadwaj, Kanchan;
Rout, Archana;
Sahoo, Pankaj Kumar;
Saurav, Suman;
Motiani, Rajender K.;
Singh, Ramandeep;
Jain, Deepti;
Asthana, Shailendra

Publication type:

Article

Role of Oxidative Stress in Metabolic Reprogramming of Brain Cancer.

Published in:

Cancers, 2023, v. 15, n. 20, p. 4920, doi. 10.3390/cancers15204920

By:

Agrawal, Kirti;
Asthana, Shailendra;
Kumar, Dhruv

Publication type:

Article

Identification and structural characterization of a pathogenic ARSA missense variant in two consanguineous families from Jammu and Kashmir (India) with late infantile metachromatic leukodystrophy.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-023-09072-2

By:

Mir, Yaser Rafiq;
Agrahari, Ashish Kumar;
Hassan, Asima;
Choudhary, Abhishek;
Asthana, Shailendra;
Taneja, Atul Kumar;
Nawaz, Shah;
Ilyas, Mohd;
Scotti, Claudia;
Kuchay, Raja A. H.

Publication type:

Article

Identification and structural characterization of a pathogenic ARSA missense variant in two consanguineous families from Jammu and Kashmir (India) with late infantile metachromatic leukodystrophy.

Published in:

Molecular Biology Reports, 2023, v. 50, n. 1, p. 1, doi. 10.1007/s11033-023-09072-2

By:

Mir, Yaser Rafiq;
Agrahari, Ashish Kumar;
Hassan, Asima;
Choudhary, Abhishek;
Asthana, Shailendra;
Taneja, Atul Kumar;
Nawaz, Shah;
Ilyas, Mohd;
Scotti, Claudia;
Kuchay, Raja A. H.

Publication type:

Article

Proteome analysis revealed the essential functions of protein phosphatase PP2A in the induction of Th9 cells.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-67845-2

By:

Roy, Suyasha;
Goel, Renu;
Aggarwal, Suruchi;
Asthana, Shailendra;
Yadav, Amit Kumar;
Awasthi, Amit

Publication type:

Article

A Molecular Analysis Provides Novel Insights into Androgen Receptor Signalling in Breast Cancer.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0120622

By:

Mehta, Jatin;
Asthana, Shailendra;
Mandal, Chandi Charan;
Saxena, Sunita

Publication type:

Article

Metabolomics Analysis and Modeling Suggest a Lysophosphocholines-PAF Receptor Interaction in Fibromyalgia.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107626

By:

Caboni, Pierluigi;
Liori, Barbara;
Kumar, Amit;
Santoru, Maria Laura;
Asthana, Shailendra;
Pieroni, Enrico;
Fais, Antonella;
Era, Benedetta;
Cacace, Enrico;
Ruggiero, Valeria;
Atzori, Luigi

Publication type:

Article

Understanding the role of conserved proline and serine residues in the SARS-CoV-2 spike cleavage sites in the virus entry, fusion, and infectivity.

Published in:

3 Biotech, 2023, v. 13, n. 10, p. 1, doi. 10.1007/s13205-023-03749-y

By:

Khatri, Ritika;
Lohiya, Bharat;
Kaur, Gurleen;
Maithil, Vikas;
Goswami, Abhishek;
Sarmadhikari, Debapriyo;
Asthana, Shailendra;
Samal, Sweety

Publication type:

Article

Crystallographic mining driven computer-guided approach to identify the ASK1 inhibitor likely to perturb the catalytic region.

Published in:

Journal of Biomolecular Structure & Dynamics, 2025, v. 43, n. 3, p. 1290, doi. 10.1080/07391102.2023.2291545

By:

Haider, Mohamad;
Sharma, Shilpa;
Agrahari, Ashish Kumar;
Dikshit, Madhu;
Pathak, Dharam Pal;
Asthana, Shailendra

Publication type:

Article

Lead phytochemicals and marine compounds against ceruloplasmin in cancer targeting.

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 23, p. 12703, doi. 10.1080/07391102.2023.2272753

By:

Arfin, Saniya;
Agrawal, Kirti;
Maurya, Sujata;
Asthana, Shailendra;
Di Silvestre, Dario;
Kumar, Dhruv

Publication type:

Article

Molecular analysis of dUTPase of Helicobacter pylori for identification of novel inhibitors using in silico studies.

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 16, p. 8598, doi. 10.1080/07391102.2023.2247080

By:

Sisodia, Rinki;
Sarmadhikari, Debapriyo;
Mazumdar, Pooja Anjali;
Asthana, Shailendra;
Madhurantakam, Chaithanya

Publication type:

Article

SARS-CoV-2 envelope protein attain K<sub>ac</sub> mediated dynamical interaction network to adopt 'histone mimic' at BRD4 interface: SARS-CoV-2 hijacking the human transcriptional machinery – a mechanistic elucidation.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 24, p. 15305, doi. 10.1080/07391102.2023.2188430

By:

Agrahari, Ashish Kumar;
Srivastava, Mitul;
Singh, Mrityunjay;
Asthana, Shailendra

Publication type:

Article

Identification and validation of potent inhibitor of Escherichia coli DHFR from MMV pathogen box.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 11, p. 5117, doi. 10.1080/07391102.2022.2080113

By:

Sharma, Shingini;
Tyagi, Rashmi;
Srivastava, Mitul;
Rani, Kusum;
Kumar, Dhruv;
Asthana, Shailendra;
Raj, V. Samuel

Publication type:

Article

Structure-based pharmacophore mapping and virtual screening of natural products to identify polypharmacological inhibitor against c-MET/EGFR/VEGFR-2.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 7, p. 2956, doi. 10.1080/07391102.2022.2042388

By:

Varma, Diksha A.;
Singh, Mrityunjay;
Wakode, Sharad;
Dinesh, N. E.;
Vinaik, Simran;
Asthana, Shailendra;
Tiwari, Manisha

Publication type:

Article

Structure-based virtual screening, molecular dynamics simulation and in vitro evaluation to identify inhibitors against NAMPT.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 20, p. 10332, doi. 10.1080/07391102.2021.1943526

By:

Panwar, Shruti;
Kumari, Anita;
Kumar, Hitesh;
Tiwari, Anoop Kumar;
Tripathi, Prabhanshu;
Asthana, Shailendra

Publication type:

Article

Computational study of novel inhibitory molecule, 1-(4-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)piperazin-1-yl)-3-phenylurea, with high potential to competitively block ATP binding to the RNA dependent RNA polymerase of SARS-CoV-2 virus.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 20, p. 10162, doi. 10.1080/07391102.2021.1940281

By:

Sharma, Prem Prakash;
Kumar, Sumit;
Srivastava, Sukrit;
Srivastava, Mitul;
Jee, Babban;
Gorobets, Nikolay Yu.;
Kumar, Dhruv;
Kumar, Mukesh;
Asthana, Shailendra;
Zhang, Peng;
Poonam;
Zoltner, Martin;
Rathi, Brijesh

Publication type:

Article

Binding mode characterization of 13b in the monomeric and dimeric states of SARS-CoV-2 main protease using molecular dynamics simulations.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 19, p. 9287, doi. 10.1080/07391102.2021.1927844

By:

Kumari, Anita;
Mittal, Lovika;
Srivastava, Mitul;
Asthana, Shailendra

Publication type:

Article

Identification and validation of potent Mycobacterial proteasome inhibitor from Enamine library.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 19, p. 8644, doi. 10.1080/07391102.2021.1914173

By:

Tyagi, Rashmi;
Srivastava, Mitul;
Singh, Baldeep;
Sharma, Shingini;
Pandey, Ramendra Pati;
Asthana, Shailendra;
Kumar, Dhruv;
Raj, V. Samuel

Publication type:

Article

Development of potential proteasome inhibitors against Mycobacterium tuberculosis.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 5, p. 2189, doi. 10.1080/07391102.2020.1835722

By:

Tyagi, Rashmi;
Srivastava, Mitul;
Jain, Preeti;
Pandey, Ramendra Pati;
Asthana, Shailendra;
Kumar, Dhruv;
Raj, V. Samuel

Publication type:

Article

Identification of potential molecules against COVID-19 main protease through structure-guided virtual screening approach.

Published in:

Journal of Biomolecular Structure & Dynamics, 2021, v. 39, n. 10, p. 3662, doi. 10.1080/07391102.2020.1768151

By:

Mittal, Lovika;
Kumari, Anita;
Srivastava, Mitul;
Singh, Mrityunjay;
Asthana, Shailendra

Publication type:

Article

Insights into structural dynamics of allosteric binding sites in HCV RNA-dependent RNA polymerase.

Published in:

Journal of Biomolecular Structure & Dynamics, 2020, v. 38, n. 6, p. 1612, doi. 10.1080/07391102.2019.1614480

By:

Mittal, Lovika;
Kumari, Anita;
Suri, Charu;
Bhattacharya, Sankar;
Asthana, Shailendra

Publication type:

Article

Front Cover: Design of 3‐Phenylcoumarins and 3‐Thienylcoumarins as Potent Xanthine Oxidase Inhibitors: Synthesis, Biological Evaluation, and Docking Studies (ChemMedChem 21/2023).

Published in:

ChemMedChem, 2023, v. 18, n. 21, p. 1, doi. 10.1002/cmdc.202300595

By:

Fais, Antonella;
Pintus, Francesca;
Era, Benedetta;
Floris, Sonia;
Kumar, Amit;
Sarmadhikari, Debapriyo;
Sogos, Valeria;
Uriarte, Eugenio;
Asthana, Shailendra;
Matos, Maria João

Publication type:

Article

Design of 3‐Phenylcoumarins and 3‐Thienylcoumarins as Potent Xanthine Oxidase Inhibitors: Synthesis, Biological Evaluation, and Docking Studies.

Published in:

ChemMedChem, 2023, v. 18, n. 21, p. 1, doi. 10.1002/cmdc.202300400

By:

Fais, Antonella;
Pintus, Francesca;
Era, Benedetta;
Floris, Sonia;
Kumar, Amit;
Sarmadhikari, Debapriyo;
Sogos, Valeria;
Uriarte, Eugenio;
Asthana, Shailendra;
Matos, Maria João

Publication type:

Article

Non-oncology drug (meticrane) shows anti-cancer ability in synergy with epigenetic inhibitors and appears to be involved passively in targeting cancer cells.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1157366

By:

Yulu Wang;
Sharma, Amit;
Fangfang Ge;
Peng Chen;
Yu Yang;
Hongjia Liu;
Hongde Liu;
Chunxia Zhao;
Mittal, Lovika;
Asthana, Shailendra;
Schmidt-Wolf, Ingo G. H.

Publication type:

Article

Elevated glycosylation of CD36 in platelets is a risk factor for oxLDL‐mediated platelet activation in type 2 diabetes.

Published in:

FEBS Journal, 2024, v. 291, n. 2, p. 376, doi. 10.1111/febs.16976

By:

Agarwal, Sakshi;
Saha, Sandhini;
Ghosh, Riya;
Sarmadhikari, Debapriyo;
Asthana, Shailendra;
Maiti, Tushar K.;
Khadgawat, Rajesh;
Guchhait, Prasenjit

Publication type:

Article