Works by Assimes, Themistocles L.


Results: 68
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    Lean body mass and risk of incident atrial fibrillation in post-menopausal women.

    Published in:
    European Heart Journal, 2016, v. 37, n. 20, p. 1606, doi. 10.1093/eurheartj/ehv423
    By:
    • Azarbal, Farnaz;
    • Stefanick, Marcia L.;
    • Assimes, Themistocles L.;
    • Manson, JoAnn E.;
    • Bea, Jennifer W.;
    • Wenjun Li;
    • Hlatky, Mark A.;
    • Larson, Joseph C.;
    • LeBlanc, Erin S.;
    • Albert, Christine M.;
    • Nassir, Rami;
    • Martin, Lisa W.;
    • Perez, Marco V.
    Publication type:
    Article
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    Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program.

    Published in:
    PLoS ONE, 2020, v. 15, n. 8, p. 1, doi. 10.1371/journal.pone.0237430
    By:
    • Serper, Marina;
    • Vujkovic, Marijana;
    • Kaplan, David E.;
    • Carr, Rotonya M.;
    • Lee, Kyung Min;
    • Shao, Qing;
    • Miller, Donald R.;
    • Reaven, Peter D.;
    • Phillips, Lawrence S.;
    • O'Donnell, Christopher J.;
    • Meigs, James B.;
    • Wilson, Peter W. F.;
    • Vickers-Smith, Rachel;
    • Kranzler, Henry R.;
    • Justice, Amy C.;
    • Gaziano, John M.;
    • Muralidhar, Sumitra;
    • Pyarajan, Saiju;
    • DuVall, Scott L.;
    • Assimes, Themistocles L.
    Publication type:
    Article
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    Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

    Published in:
    Nature Genetics, 2011, v. 43, n. 4, p. 333, doi. 10.1038/ng.784
    By:
    • Schunkert, Heribert;
    • König, Inke R.;
    • Kathiresan, Sekar;
    • Reilly, Muredach P.;
    • Assimes, Themistocles L.;
    • Holm, Hilma;
    • Preuss, Michael;
    • Stewart, Alexandre F. R.;
    • Barbalic, Maja;
    • Gieger, Christian;
    • Absher, Devin;
    • Aherrahrou, Zouhair;
    • Allayee, Hooman;
    • Altshuler, David;
    • Anand, Sonia S;
    • Andersen, Karl;
    • Anderson, Jeffrey L.;
    • Ardissino, Diego;
    • Ball, Stephen G.;
    • Balmforth, Anthony J.
    Publication type:
    Article
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    Genome-wide meta-analyses identify multiple loci associated with smoking behavior.

    Published in:
    Nature Genetics, 2010, v. 42, n. 5, p. 441, doi. 10.1038/ng.571
    By:
    • Furberg, Helena;
    • YunJung Kim;
    • Dackor, Jennifer;
    • Boerwinkle, Eric;
    • Franceschini, Nora;
    • Ardissino, Diego;
    • Bernardinelli, Luisa;
    • Mannucci, Pier M.;
    • Mauri, Francesco;
    • Merlini, Piera A.;
    • Absher, Devin;
    • Assimes, Themistocles L.;
    • Fortmann, Stephen P.;
    • Iribarren, Carlos;
    • Knowles, Joshua W.;
    • Quertermous, Thomas;
    • Ferrucci, Luigi;
    • Tanaka, Toshiko;
    • Bis, Joshua C.;
    • Furberg, Curt D.
    Publication type:
    Article
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    Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of <i>TCF21</i> Expression at the 6q23.2 Coronary Heart Disease Locus.

    Published in:
    PLoS Genetics, 2013, v. 9, n. 7, p. 1, doi. 10.1371/journal.pgen.1003652
    By:
    • Miller, Clint L.;
    • Anderson, D. Ryan;
    • Kundu, Ramendra K.;
    • Raiesdana, Azad;
    • Nürnberg, Sylvia T.;
    • Diaz, Roxanne;
    • Cheng, Karen;
    • Leeper, Nicholas J.;
    • Chen, Chung-Hsing;
    • Chang, I-Shou;
    • Schadt, Eric E.;
    • Hsiung, Chao Agnes;
    • Assimes, Themistocles L.;
    • Quertermous, Thomas
    Publication type:
    Article
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    Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene.

    Published in:
    2016
    By:
    • Knowles, Joshua W;
    • Xie, Weijia;
    • Zhang, Zhongyang;
    • Chennamsetty, Indumathi;
    • Assimes, Themistocles L;
    • Paananen, Jussi;
    • Hansson, Ola;
    • Pankow, James;
    • Goodarzi, Mark O;
    • Carcamo-Orive, Ivan;
    • Morris, Andrew P;
    • Chen, Yii-Der I;
    • Mäkinen, Ville-Petteri;
    • Ganna, Andrea;
    • Mahajan, Anubha;
    • Guo, Xiuqing;
    • Abbasi, Fahim;
    • Greenawalt, Danielle M;
    • Lum, Pek;
    • Molony, Cliona
    Publication type:
    corrected article
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    Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene.

    Published in:
    Journal of Clinical Investigation, 2015, v. 125, n. 4, p. 1739, doi. 10.1172/JCI74692
    By:
    • Knowles, Joshua W.;
    • Weijia Xie;
    • Zhongyang Zhang;
    • Chennemsetty, Indumathi;
    • Assimes, Themistocles L.;
    • Paananen, Jussi;
    • Hansson, Ola;
    • Pankow, James;
    • Goodarzi, Mark O.;
    • Carcamo-Orive, Ivan;
    • Morris, Andrew P.;
    • Chen, Yii-Der I.;
    • Mäkinen, Ville-Petteri;
    • Ganna, Andrea;
    • Mahajan, Anubha;
    • Xiuqing Guo;
    • Abbasi, Fahim;
    • Greenawalt, Danielle M.;
    • Pek Lum;
    • Molony, Cliona
    Publication type:
    Article
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    Circulating brain-derived neurotrophic factor concentrations and the risk of cardiovascular disease in the community.

    Published in:
    2015
    By:
    • Kaess, Bernhard M.;
    • Preis, Sarah R.;
    • Lieb, Wolfgang;
    • Beiser, Alexa S.;
    • Yang, Qiong;
    • Chen, Tai C.;
    • Hengstenberg, Christian;
    • Erdmann, Jeanette;
    • Schunkert, Heribert;
    • Seshadri, Sudha;
    • Vasan, Ramachandran S.;
    • CARDIoGRAM;
    • Assimes, Themistocles L;
    • Deloukas, Panos;
    • Holm, Hilma;
    • Kathiresan, Sekar;
    • König, Inke R;
    • McPherson, Ruth;
    • Reilly, Muredach P;
    • Roberts, Robert
    Publication type:
    journal article
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    Genetic determinants of increased body mass index mediate the effect of smoking on increased risk for type 2 diabetes but not coronary artery disease.

    Published in:
    Human Molecular Genetics, 2020, v. 29, n. 19, p. 3327, doi. 10.1093/hmg/ddaa193
    By:
    • Thom, Christopher S.;
    • Zhuoran Ding;
    • Levin, Michael G.;
    • Damrauer, Scott M.;
    • Kyung Min Lee;
    • Lynch, Julie;
    • Kyong-Mi Chang;
    • Tsao, Philip S.;
    • Cho, Kelly;
    • Wilson, Peter W. F.;
    • Assimes, Themistocles L.;
    • Sun, Yan V.;
    • O’Donnell, Christopher J.;
    • Vujkovic, Marijana;
    • Voight, Benjamin F.
    Publication type:
    Article
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    Defining the role of common variation in the genomic and biological architecture of adult human height.

    Published in:
    Nature Genetics, 2014, v. 46, n. 11, p. 1173, doi. 10.1038/ng.3097
    By:
    • Wood, Andrew R;
    • Pasko, Dorota;
    • Weedon, Michael N;
    • Frayling, Timothy M;
    • Kutalik, Zoltán;
    • Hassinen, Maija;
    • Hayward, Caroline;
    • Wright, Alan F;
    • Heard-Costa, Nancy L;
    • Helmer, Quinta;
    • Hillege, Hans L;
    • Hlatky, Mark A;
    • Assimes, Themistocles L;
    • Quertermous, Thomas;
    • Hoffmann, Wolfgang;
    • Völzke, Henry;
    • Hoffmann, Per;
    • Holmen, Oddgeir;
    • Hveem, Kristian;
    • Houwing-Duistermaat, Jeanine J
    Publication type:
    Article
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    Large-scale association analysis identifies new risk loci for coronary artery disease.

    Published in:
    Nature Genetics, 2013, v. 45, n. 1, p. 25, doi. 10.1038/ng.2480
    By:
    • Deloukas, Panos;
    • Kanoni, Stavroula;
    • Willenborg, Christina;
    • Farrall, Martin;
    • Assimes, Themistocles L;
    • Thompson, John R;
    • Ingelsson, Erik;
    • Saleheen, Danish;
    • Erdmann, Jeanette;
    • Goldstein, Benjamin A;
    • Stirrups, Kathleen;
    • König, Inke R;
    • Cazier, Jean-Baptiste;
    • Johansson, Åsa;
    • Hall, Alistair S;
    • Lee, Jong-Young;
    • Willer, Cristen J;
    • Chambers, John C;
    • Esko, Tõnu;
    • Folkersen, Lasse
    Publication type:
    Article
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    Rare coding variants in RCN3 are associated with blood pressure.

    Published in:
    BMC Genomics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12864-022-08356-4
    By:
    • He, Karen Y.;
    • Kelly, Tanika N.;
    • Wang, Heming;
    • Liang, Jingjing;
    • Zhu, Luke;
    • Cade, Brian E.;
    • Assimes, Themistocles L.;
    • Becker, Lewis C.;
    • Beitelshees, Amber L.;
    • Bielak, Lawrence F.;
    • Bress, Adam P.;
    • Brody, Jennifer A.;
    • Chang, Yen-Pei Christy;
    • Chang, Yi-Cheng;
    • de Vries, Paul S.;
    • Duggirala, Ravindranath;
    • Fox, Ervin R.;
    • Franceschini, Nora;
    • Furniss, Anna L.;
    • Gao, Yan
    Publication type:
    Article
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    Genetic Loci Associated With COVID-19 Positivity and Hospitalization in White, Black, and Hispanic Veterans of the VA Million Veteran Program.

    Published in:
    Frontiers in Genetics, 2022, v. 12, p. 1, doi. 10.3389/fgene.2021.777076
    By:
    • Peloso, Gina M.;
    • Tcheandjieu, Catherine;
    • McGeary, John E.;
    • Posner, Daniel C.;
    • Ho, Yuk-Lam;
    • Zhou, Jin J.;
    • Hilliard, Austin T.;
    • Joseph, Jacob;
    • O'Donnell, Christopher J.;
    • Efird, Jimmy T.;
    • Crawford, Dana C.;
    • Wu, Wen-Chih;
    • Arjomandi, Mehrdad;
    • Sun, Yan V.;
    • Assimes, Themistocles L;
    • Huffman, Jennifer E.
    Publication type:
    Article
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    Multi-Trait Genome-Wide Association Study of Atherosclerosis Detects Novel Pleiotropic Loci.

    Published in:
    Frontiers in Genetics, 2022, v. 12, p. 1, doi. 10.3389/fgene.2021.787545
    By:
    • Bellomo, Tiffany R.;
    • Bone, William P.;
    • Chen, Brian Y.;
    • Gawronski, Katerina A. B.;
    • Zhang, David;
    • Park, Joseph;
    • Levin, Michael;
    • Tsao, Noah;
    • Klarin, Derek;
    • Lynch, Julie;
    • Assimes, Themistocles L.;
    • Gaziano, J. Michael;
    • Wilson, Peter W.;
    • Cho, Kelly;
    • Vujkovic, Marijana;
    • the VA Million Veteran Program;
    • O'Donnell, Christopher J.;
    • Chang, Kyong-Mi;
    • Tsao, Philip S.;
    • Rader, Daniel J.
    Publication type:
    Article
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    Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study.

    Published in:
    Human Molecular Genetics, 2008, v. 17, n. 15, p. 2320, doi. 10.1093/hmg/ddn132
    By:
    • Assimes, Themistocles L.;
    • Knowles, Joshua W.;
    • Basu, Analabha;
    • Iribarren, Carlos;
    • Southwick, Audrey;
    • Tang, Hua;
    • Absher, Devin;
    • Li, Jun;
    • Fair, Joan M.;
    • Rubin, Geoffrey D.;
    • Sidney, Stephen;
    • Fortmann, Stephen P.;
    • Go, Alan S.;
    • Hlatky, Mark A.;
    • Myers, Richard M.;
    • Risch, Neil;
    • Quertermous, Thomas
    Publication type:
    Article
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    Genomics and phenomics of body mass index reveals a complex disease network.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35553-2
    By:
    • Huang, Jie;
    • Huffman, Jennifer E.;
    • Huang, Yunfeng;
    • Do Valle, Ítalo;
    • Assimes, Themistocles L.;
    • Raghavan, Sridharan;
    • Voight, Benjamin F.;
    • Liu, Chang;
    • Barabási, Albert-László;
    • Huang, Rose D. L.;
    • Hui, Qin;
    • Nguyen, Xuan-Mai T.;
    • Ho, Yuk-Lam;
    • Djousse, Luc;
    • Lynch, Julie A.;
    • Vujkovic, Marijana;
    • Tcheandjieu, Catherine;
    • Tang, Hua;
    • Damrauer, Scott M.;
    • Reaven, Peter D.
    Publication type:
    Article
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    Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci.

    Published in:
    Nature Communications, 2016, v. 7, n. 7, p. 12092, doi. 10.1038/ncomms12092
    By:
    • Miller, Clint L.;
    • Pjanic, Milos;
    • Wang, Ting;
    • Nguyen, Trieu;
    • Cohain, Ariella;
    • Lee, Jonathan D.;
    • Perisic, Ljubica;
    • Hedin, Ulf;
    • Kundu, Ramendra K.;
    • Majmudar, Deshna;
    • Kim, Juyong B.;
    • Wang, Oliver;
    • Betsholtz, Christer;
    • Ruusalepp, Arno;
    • Franzén, Oscar;
    • Assimes, Themistocles L.;
    • Montgomery, Stephen B.;
    • Schadt, Eric E.;
    • Björkegren, Johan L.M.;
    • Quertermous, Thomas
    Publication type:
    Article
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    Associations between DNA methylation and BMI vary by metabolic health status: a potential link to disparate cardiovascular outcomes.

    Published in:
    Clinical Epigenetics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13148-021-01194-3
    By:
    • Do, Whitney L.;
    • Nguyen, Steve;
    • Yao, Jie;
    • Guo, Xiuqing;
    • Whitsel, Eric A.;
    • Demerath, Ellen;
    • Rotter, Jerome I.;
    • Rich, Stephen S.;
    • Lange, Leslie;
    • Ding, Jingzhong;
    • Van Den Berg, David;
    • Liu, Yongmei;
    • Justice, Anne E.;
    • Guan, Weihua;
    • Horvath, Steve;
    • Assimes, Themistocles L.;
    • Bhatti, Parveen;
    • Jordahl, Kristina;
    • Shadyab, Aladdin;
    • Valencia, Celina I.
    Publication type:
    Article
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    Leukocyte Traits and Exposure to Ambient Particulate Matter Air Pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study.

    Published in:
    Environmental Health Perspectives, 2020, v. 128, n. 1, p. 017004-1, doi. 10.1289/EHP5360
    By:
    • Gondalia, Rahul;
    • Holliday, Katelyn M.;
    • Baldassari, Antoine;
    • Justice, Anne E.;
    • Stewart, James D.;
    • Duanping Liao;
    • Yanosky, Jeff D.;
    • Engel, Stephanie M.;
    • Jordahl, Kristina M.;
    • Bhatti, Parveen;
    • Horvath, Steve;
    • Assimes, Themistocles L.;
    • Pankow, James S.;
    • Demerath, Ellen W.;
    • Guan, Weihua;
    • Fornage, Myriam;
    • Bressler, Jan;
    • North, Kari E.;
    • Conneely, Karen N.;
    • Yun Li
    Publication type:
    Article
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    Associations of blood lipids and LDL cholesterol lowering drug-targets with colorectal cancer risk: a Mendelian randomisation study: Epidemiology.

    Published in:
    British Journal of Cancer, 2025, v. 132, n. 1, p. 103, doi. 10.1038/s41416-024-02900-7
    By:
    • Chan, Wing Ching;
    • Liu, Lili;
    • Bouras, Emmanouil;
    • Zuber, Verena;
    • Wen, Wanqing;
    • Long, Jirong;
    • Gill, Dipender;
    • Murphy, Neil;
    • Gunter, Marc J.;
    • Assimes, Themistocles L.;
    • Bujanda, Luis;
    • Gruber, Stephen B.;
    • Küry, Sébastien;
    • Lynch, Brigid M.;
    • Qu, Conghui;
    • Thomas, Minta;
    • White, Emily;
    • Woods, Michael O.;
    • Peters, Ulrike;
    • Li, Christopher I.
    Publication type:
    Article
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    Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data.

    Published in:
    Human Genetics, 2019, v. 138, n. 2, p. 199, doi. 10.1007/s00439-019-01975-0
    By:
    • He, Karen Y.;
    • Li, Xiaoyin;
    • Kelly, Tanika N.;
    • Liang, Jingjing;
    • Cade, Brian E.;
    • Assimes, Themistocles L.;
    • Becker, Lewis C.;
    • Beitelshees, Amber L.;
    • Bress, Adam P.;
    • Chang, Yen-Pei Christy;
    • Chen, Yii-Der Ida;
    • de Vries, Paul S.;
    • Fox, Ervin R.;
    • Franceschini, Nora;
    • Furniss, Anna;
    • Gao, Yan;
    • Guo, Xiuqing;
    • Haessler, Jeffrey;
    • Hwang, Shih-Jen;
    • Irvin, Marguerite Ryan
    Publication type:
    Article
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    Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity.

    Published in:
    Diabetes, 2014, v. 63, n. 6, p. 2158, doi. 10.2337/db13-0949
    By:
    • Dimas, Antigone S.;
    • Lagou, Vasiliki;
    • Barker, Adam;
    • Knowles, Joshua W.;
    • Mägi, Reedik;
    • Hivert, Marie-France;
    • Benazzo, Andrea;
    • Rybin, Denis;
    • Jackson, Anne U.;
    • Stringham, Heather M.;
    • Ci Song;
    • Fischer-Rosinsky, Antje;
    • Boesgaard, Trine Welløv;
    • Grarup, Niels;
    • Abbasi, Fahim A.;
    • Assimes, Themistocles L.;
    • Ke Hao;
    • Xia Yang;
    • Lecoeur, Cécile;
    • Barroso, Inês
    Publication type:
    Article
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    Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes.

    Published in:
    Diabetes, 2013, v. 62, n. 6, p. 2141, doi. 10.2337/db12-0876
    By:
    • Weijia Xie;
    • Wood, Andrew R.;
    • Lyssenko, Valeriya;
    • Weedon, Michael N.;
    • Knowles, Joshua W.;
    • Alkayyali, Sami;
    • Assimes, Themistocles L.;
    • Quertermous, Thomas;
    • Abbasi, Fahim;
    • Paananen, Jussi;
    • Häring, Hans;
    • Hansen, Torben;
    • Pedersen, Oluf;
    • Smith, Ulf;
    • Laakso, Markku;
    • Dekker, Jacqueline M.;
    • Nolan, John J.;
    • Groop, Leif;
    • Ferrannini, Ele;
    • Adam, Klaus-Peter
    Publication type:
    Article