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Tankyrase-targeted therapeutics: expanding opportunities in the PARP family.
- Published in:
- Nature Reviews Drug Discovery, 2012, v. 11, n. 12, p. 923, doi. 10.1038/nrd3868
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- Publication type:
- Article
Utilizing RNA interference to enhance cancer drug discovery.
- Published in:
- 2007
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- Publication type:
- journal article
Targeting Tropomyosin Receptor Kinase in Cutaneous CYLD Defective Tumors With Pegcantratinib: The TRAC Randomized Clinical Trial.
- Published in:
- 2018
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- Publication type:
- journal article
Exome sequencing of an adult pituitary atypical teratoid rhabdoid tumor.
- Published in:
- Frontiers in Oncology, 2015, p. 1, doi. 10.3389/fonc.2015.00236
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- Publication type:
- Article
Secular trends in age at menarche in women in the UK born 1908-93: results from the Breakthrough Generations Study.
- Published in:
- 2011
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- Publication type:
- journal article
Familial concordance for age at menarche: analyses from the Breakthrough Generations Study.
- Published in:
- 2011
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- Publication type:
- journal article
Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells.
- Published in:
- EMBO Molecular Medicine, 2012, v. 4, n. 10, p. 1087, doi. 10.1002/emmm.201201250
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- Publication type:
- Article
Aurora-A expressing tumour cells are deficient for homology-directed DNA double strand-break repair and sensitive to PARP inhibition.
- Published in:
- EMBO Molecular Medicine, 2010, v. 2, n. 4, p. 130, doi. 10.1002/emmm.201000068
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- Publication type:
- Article
Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors.
- Published in:
- EMBO Molecular Medicine, 2009, v. 1, n. 6/7, p. 315, doi. 10.1002/emmm.200900041
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- Publication type:
- Article
Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2.
- Published in:
- EMBO Molecular Medicine, 2009, v. 1, n. 6/7, p. 323, doi. 10.1002/emmm.200900040
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- Publication type:
- Article
Regional anaesthesia: awake or asleep?
- Published in:
- British Journal of Hospital Medicine (17508460), 2011, v. 72, n. 3, p. 178, doi. 10.12968/hmed.2011.72.3.178
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- Article
Reversion to sinus rhythm after induction of general anaesthesia.
- Published in:
- 2010
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- Publication type:
- Letter
Profiling familial breast cancer.
- Published in:
- Nature Medicine, 2001, v. 7, n. 4, p. 408, doi. 10.1038/86464
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- Publication type:
- Article
Overexpression of MYB drives proliferation of CYLD-defective cylindroma cells.
- Published in:
- Journal of Pathology, 2016, v. 239, n. 2, p. 197, doi. 10.1002/path.4717
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- Publication type:
- Article
Whole-exome DNA sequence analysis of Brca2- and Trp53-deficient mouse mammary gland tumours.
- Published in:
- Journal of Pathology, 2015, v. 236, n. 2, p. 186, doi. 10.1002/path.4517
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- Publication type:
- Article
Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction.
- Published in:
- EMBO Journal, 2005, v. 24, n. 10, p. 1810, doi. 10.1038/sj.emboj.7600667
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- Publication type:
- Article
Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences.
- Published in:
- EMBO Journal, 2001, v. 20, n. 17, p. 4704, doi. 10.1093/emboj/20.17.4704
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- Publication type:
- Article
Klotho: A Major Shareholder in Vascular Aging Enterprises.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 18, p. 4637, doi. 10.3390/ijms20184637
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- Publication type:
- Article
Parity reduces mammary repopulating activity but does not affect mammary stem cells defined as CD24 + CD29/CD49fhi in mice.
- Published in:
- Breast Cancer Research & Treatment, 2020, v. 183, n. 3, p. 565, doi. 10.1007/s10549-020-05804-1
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- Publication type:
- Article
Structural basis for recruitment of BRCA2 by PALB2.
- Published in:
- EMBO Reports, 2009, v. 10, n. 9, p. 990, doi. 10.1038/embor.2009.126
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- Publication type:
- Article
p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene.
- Published in:
- EMBO Reports, 2006, v. 7, n. 2, p. 219, doi. 10.1038/sj.embor.7400587
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- Publication type:
- Article
DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells.
- Published in:
- EMBO Reports, 2004, v. 5, n. 10, p. 989, doi. 10.1038/sj.embor.7400255
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- Publication type:
- Article
A targeted deletion in the endocytic receptor gene Endo180 results in a defect in collagen uptake.
- Published in:
- EMBO Reports, 2003, v. 4, n. 7, p. 710, doi. 10.1038/sj.embor.embor882
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- Publication type:
- Article
Disruption of Brca2 increases the spontaneous mutation rate in vivo: synergism with ionizing radiation.
- Published in:
- EMBO Reports, 2002, v. 3, n. 3, p. 255, doi. 10.1093/embo-reports/kvf037
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- Publication type:
- Article
Genome-wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. 10, p. 6270, doi. 10.1093/nar/gku299
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- Publication type:
- Article
Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation.
- Published in:
- Nucleic Acids Research, 2012, v. 40, n. 15, p. 7190, doi. 10.1093/nar/gks389
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- Publication type:
- Article
An in vivo model of intratumoural aromatase using aromatase-transfected MCF7 human breast cancer cells.
- Published in:
- International Journal of Cancer, 1995, v. 62, n. 3, p. 297, doi. 10.1002/ijc.2910620311
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- Publication type:
- Article
An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24919-7
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- Publication type:
- Article
Multiparameter single-cell proteomic technologies give new insights into the biology of ovarian tumors.
- Published in:
- Seminars in Immunopathology, 2023, v. 45, n. 1, p. 43, doi. 10.1007/s00281-022-00979-9
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- Publication type:
- Article
Targeting p90 Ribosomal S6 Kinase Eliminates Tumor-Initiating Cells by Inactivating Y-Box Binding Protein-1 in Triple-Negative Breast Cancers.
- Published in:
- Stem Cells, 2012, v. 30, n. 7, p. 1338, doi. 10.1002/stem.1128
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- Publication type:
- Article
Mechanisms of resistance to therapies targeting BRCA-mutant cancers.
- Published in:
- Nature Medicine, 2013, v. 19, n. 11, p. 1381, doi. 10.1038/nm.3369
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- Publication type:
- Article
Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor.
- Published in:
- Journal of Pathology, 2013, v. 229, n. 3, p. 422, doi. 10.1002/path.4140
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- Publication type:
- Article
Functional characterization of EMSY gene amplification in human cancers.
- Published in:
- Journal of Pathology, 2011, v. 225, n. 1, p. 29, doi. 10.1002/path.2944
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- Publication type:
- Article
Transition from cylindroma to spiradenoma in CYLD-defective tumours is associated with reduced DKK2 expression.
- Published in:
- Journal of Pathology, 2011, v. 224, n. 3, p. 309, doi. 10.1002/path.2896
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- Publication type:
- Article
Mucinous carcinoma of the breast is genomically distinct from invasive ductal carcinomas of no special type.
- Published in:
- Journal of Pathology, 2010, v. 222, n. 3, p. 282, doi. 10.1002/path.2763
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- Publication type:
- Article
Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas.
- Published in:
- Journal of Pathology, 2010, v. 220, n. 5, p. 562, doi. 10.1002/path.2675
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- Publication type:
- Article
Genomic instability and the selection of treatments for cancer.
- Published in:
- Journal of Pathology, 2010, v. 220, n. 2, p. 281, doi. 10.1002/path.2631
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- Publication type:
- Article
Conditional deletion of the Lkb1 gene in the mouse mammary gland induces tumour formation.
- Published in:
- Journal of Pathology, 2009, v. 219, n. 3, p. 306, doi. 10.1002/path.2599
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- Publication type:
- Article
Genome-wide transcriptomic profiling of microdissected human breast tissue reveals differential expression of KIT (c-Kit, CD117) and oestrogen receptor-α (ERα) in response to therapeutic radiation.
- Published in:
- Journal of Pathology, 2009, v. 219, n. 1, p. 131, doi. 10.1002/path.2581
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- Publication type:
- Article
Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray-based CGH analysis.
- Published in:
- Journal of Pathology, 2009, v. 219, n. 1, p. 16, doi. 10.1002/path.2574
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- Publication type:
- Article
Mixed micropapillary-ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components.
- Published in:
- Journal of Pathology, 2009, v. 218, n. 3, p. 301, doi. 10.1002/path.2572
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- Publication type:
- Article
AXL and acquired resistance to EGFR inhibitors.
- Published in:
- Nature Genetics, 2012, v. 44, n. 8, p. 835, doi. 10.1038/ng.2362
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- Publication type:
- Article
ESR1 gene amplification in breast cancer: a common phenomenon?
- Published in:
- 2008
- By:
- Publication type:
- Letter
A new gene on the X involved in Fanconi anemia.
- Published in:
- Nature Genetics, 2004, v. 36, n. 11, p. 1142, doi. 10.1038/ng1104-1142
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- Publication type:
- Article
Changes in estradiol and testosterone levels in postmenopausal women after changes in body mass index.
- Published in:
- 2013
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- Publication type:
- journal article
Retroviral vectors for establishing tetracycline-regulated gene expression in an otherwise recalcitrant cell line.
- Published in:
- BMC Molecular Biology, 2002, v. 3, p. 13, doi. 10.1186/1471-2199-3-13
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- Publication type:
- Article
Neuregulin3 alters cell fate in the epidermis and mammary gland.
- Published in:
- BMC Developmental Biology, 2007, v. 7, p. 105, doi. 10.1186/1471-213X-7-105
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- Publication type:
- Article
RAD51, BRCA2 and DNA repair: a partial resolution.
- Published in:
- Nature Structural & Molecular Biology, 2007, v. 14, n. 6, p. 461, doi. 10.1038/nsmb0607-461
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- Publication type:
- Article
Distribution and significance of nerve growth factor receptor (NGFR/p75NTR) in normal, benign and malignant breast tissue.
- Published in:
- 2006
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- Publication type:
- journal article
Expression of sox11 gene duplicates in zebrafish suggests the reciprocal loss of ancestral gene expression patterns in development.
- Published in:
- Developmental Dynamics, 2000, v. 217, n. 3, p. 279, doi. 10.1002/(SICI)1097-0177(200003)217:3<279::AID-DVDY6>3.0.CO;2-S
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- Publication type:
- Article