Works by Asano, Tomoichiro

Results: 70

PI3K and Btk differentially regulate B cell antigen receptor-mediated signal transduction.

Published in:

Nature Immunology, 2003, v. 4, n. 3, p. 280, doi. 10.1038/ni890

By:

Suzuki, Harumi;
Matsuda, Satoshi;
Terauchi, Yasuo;
Fujiwara, Mari;
Ohteki, Toshiaki;
Asano, Tomoichiro;
Behrens, Timothy W.;
Kouro, Taku;
Takatsu, Kiyoshi;
Kadowaki, Takashi;
Koyasu, Shigeo

Publication type:

Article

PI3K-mediated negative feedback regulation of IL-12 production in DCs.

Published in:

Nature Immunology, 2002, v. 3, n. 9, p. 875, doi. 10.1038/ni825

By:

Fukao, Taro;
Tanabe, Masanobu;
Terauchi, Yasuo;
Ota, Takayuki;
Matsuda, Satoshi;
Asano, Tomoichiro;
Kadowaki, Takashi;
Takeuchi, Tsutomu;
Koyasu, Shigeo

Publication type:

Article

Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice.

Published in:

Nature Immunology, 2002, v. 3, n. 3, p. 295, doi. 10.1038/ni768

By:

Fukao, Taro;
Yamada, Taketo;
Tanabe, Masanobu;
Terauchi, Yasuo;
Ota, Takayuki;
Takayama, Tetsuro;
Asano, Tomoichiro;
Takeuchi, Tsutomu;
Kadowaki, Takashi;
Hata, Jun-ichi;
Koyasu, Shigeo

Publication type:

Article

Possible involvement of normalized Pin1 expression level and AMPK activation in the molecular mechanisms underlying renal protective effects of SGLT2 inhibitors in mice.

Published in:

Diabetology & Metabolic Syndrome, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13098-019-0454-6

By:

Inoue, Masa-Ki;
Matsunaga, Yasuka;
Nakatsu, Yusuke;
Yamamotoya, Takeshi;
Ueda, Koji;
Kushiyama, Akifumi;
Sakoda, Hideyuki;
Fujishiro, Midori;
Ono, Hiraku;
Iwashita, Misaki;
Sano, Tomomi;
Nishimura, Fusanori;
Morii, Kenichi;
Sasaki, Kensuke;
Masaki, Takao;
Asano, Tomoichiro

Publication type:

Article

Fluorescent indicators for imaging protein phosphorylation in single living cells.

Published in:

Nature Biotechnology, 2002, v. 20, n. 3, p. 287, doi. 10.1038/nbt0302-287

By:

Sato, Moritoshi;
Ozawa, Takeaki;
Inukai, Kouichi;
Asano, Tomoichiro;
Umezawa, Yoshio

Publication type:

Article

Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.

Published in:

Mediators of Inflammation, 2016, p. 1, doi. 10.1155/2016/8603164

By:

Kushiyama, Akifumi;
Nakatsu, Yusuke;
Matsunaga, Yasuka;
Yamamotoya, Takeshi;
Mori, Keiichi;
Ueda, Koji;
Inoue, Yuki;
Sakoda, Hideyuki;
Fujishiro, Midori;
Ono, Hiraku;
Asano, Tomoichiro

Publication type:

Article

The inflammation–lipocalin 2 axis may contribute to the development of chronic kidney disease.

Published in:

Nephrology Dialysis Transplantation, 2014, v. 29, n. 3, p. 611, doi. 10.1093/ndt/gft449

By:

Hashikata, Atsushi;
Yamashita, Akiko;
Suzuki, Shigeki;
Nagayasu, Shintaro;
Shinjo, Takanori;
Taniguchi, Ataru;
Fukushima, Mitsuo;
Nakai, Yoshikatsu;
Nin, Kazuko;
Watanabe, Naoya;
Asano, Tomoichiro;
Abiko, Yoshimitsu;
Kushiyama, Akifumi;
Nagasaka, Shoichiro;
Nishimura, Fusanori

Publication type:

Article

Impact of Plasma Xanthine Oxidoreductase Activity on the Mechanisms of Distal Symmetric Polyneuropathy Development in Patients with Type 2 Diabetes.

Published in:

Biomedicines, 2021, v. 9, n. 8, p. 1052, doi. 10.3390/biomedicines9081052

By:

Fujishiro, Midori;
Ishihara, Hisamitsu;
Ogawa, Katsuhiko;
Murase, Takayo;
Nakamura, Takashi;
Watanabe, Kentaro;
Sakoda, Hideyuki;
Ono, Hiraku;
Yamamotoya, Takeshi;
Nakatsu, Yusuke;
Asano, Tomoichiro;
Kushiyama, Akifumi

Publication type:

Article

Pathological Role of Pin1 in the Development of DSS-Induced Colitis.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1230, doi. 10.3390/cells10051230

By:

Matsunaga, Yasuka;
Hasei, Shun;
Yamamotoya, Takeshi;
Honda, Hiroaki;
Kushiyama, Akifumi;
Sakoda, Hideyuki;
Fujishiro, Midori;
Ono, Hiraku;
Ito, Hisanaka;
Okabe, Takayoshi;
Asano, Tomoichiro;
Nakatsu, Yusuke;
Fiorucci, Stefano

Publication type:

Article

Pin1 Plays Essential Roles in NASH Development by Modulating Multiple Target Proteins.

Published in:

Cells (2073-4409), 2019, v. 8, n. 12, p. 1545, doi. 10.3390/cells8121545

By:

Inoue, Masa-Ki;
Nakatsu, Yusuke;
Yamamotoya, Takeshi;
Hasei, Shun;
Kanamoto, Mayu;
Naitou, Miki;
Matsunaga, Yasuka;
Sakoda, Hideyuki;
Fujishiro, Midori;
Ono, Hiraku;
Kushiyama, Akifumi;
Asano, Tomoichiro

Publication type:

Article

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85α subunit of phosphoinositide 3?kinase.

Published in:

Nature Genetics, 1999, v. 21, n. 2, p. 230, doi. 10.1038/6023

By:

Terauchi, Yasuo;
Tsuji, Youki;
Satoh, Shinobu;
Minoura, Hideaki;
Murakami, Koji;
Okuno, Akira;
Inukai, Kouichi;
Asano, Tomoichiro;
Kaburagi, Yasushi;
Ueki, Kohjiro;
Nakajima, Hiromu;
Hanafusa, Toshiaki;
Matsuzawa, Yuji;
Sekihara, Hisahiko;
Yin, Yuxin;
Barrett, J. Carl;
Oda, Hideaki;
Ishikawa, Takatoshi;
Akanuma, Yasuo

Publication type:

Article

Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest.

Published in:

2010

By:

Kawamura, Yumiko;
Uchijima, Yasunobu;
Horike, Nanao;
Tonami, Kazuo;
Nishiyama, Koichi;
Amano, Tomokazu;
Asano, Tomoichiro;
Kurihara, Yukiko;
Kurihara, Hiroki

Publication type:

journal article

Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats.

Published in:

2008

By:

Ono, Hiraku;
Pocai, Alessandro;
Wang, Yuhua;
Sakoda, Hideyuki;
Asano, Tomoichiro;
Backer, Jonathan M.;
Schwartz, Gary J.;
Rossetti, Luciano

Publication type:

journal article

Protection from diet-induced obesity and insulin resistance in mice lacking CCL19-CCR7 signaling.

Published in:

Obesity (19307381), 2015, v. 23, n. 7, p. 1460, doi. 10.1002/oby.21127

By:

Sano, Tomomi;
Iwashita, Misaki;
Nagayasu, Shintaro;
Yamashita, Akiko;
Shinjo, Takanori;
Hashikata, Atsushi;
Asano, Tomoichiro;
Kushiyama, Akifumi;
Ishimaru, Naozumi;
Takahama, Yousuke;
Nishimura, Fusanori

Publication type:

Article

Insulin receptor substrate-1 associates with small nucleolar RNA which contributes to ribosome biogenesis.

Published in:

Frontiers in Endocrinology, 2014, v. 5, p. 1, doi. 10.3389/fendo.2014.00024

By:

Ozoe, Atsufumi;
Sone, Meri;
Fukushima, Toshiaki;
Kataoka, Naoyuki;
Chida, Kazuhiro;
Asano, Tomoichiro;
Hakuno, Fumihiko;
Takahashi, Shin-Ichiro

Publication type:

Article

Importance of endothelial NF-κB signalling in vascular remodelling and aortic aneurysm formation.

Published in:

Cardiovascular Research, 2013, v. 97, n. 1, p. 106, doi. 10.1093/cvr/cvs298

By:

Saito, Tokuo;
Hasegawa, Yutaka;
Ishigaki, Yasushi;
Yamada, Tetsuya;
Gao, Junhong;
Imai, Junta;
Uno, Kenji;
Kaneko, Keizo;
Ogihara, Takehide;
Shimosawa, Tatsuo;
Asano, Tomoichiro;
Fujita, Toshiro;
Oka, Yoshitomo;
Katagiri, Hideki

Publication type:

Article

Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 21, p. 16011, doi. 10.3390/ijms242116011

By:

Akasaka, Yasuyuki;
Hasei, Shun;
Ohata, Yukino;
Kanna, Machi;
Nakatsu, Yusuke;
Sakoda, Hideyuki;
Fujishiro, Midori;
Kushiyama, Akifumi;
Ono, Hiraku;
Matsubara, Akio;
Hinata, Nobuyuki;
Asano, Tomoichiro;
Yamamotoya, Takeshi

Publication type:

Article

Hepatic Pin1 Expression, Particularly in Nuclei, Is Increased in NASH Patients in Accordance with Evidence of the Role of Pin1 in Lipid Accumulation Shown in Hepatoma Cell Lines.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 10, p. 8847, doi. 10.3390/ijms24108847

By:

Kanna, Machi;
Nakatsu, Yusuke;
Yamamotoya, Takeshi;
Kushiyama, Akifumi;
Fujishiro, Midori;
Sakoda, Hideyuki;
Ono, Hiraku;
Arihiro, Koji;
Asano, Tomoichiro

Publication type:

Article

Carnosic Acid and Carnosol Activate AMPK, Suppress Expressions of Gluconeogenic and Lipogenic Genes, and Inhibit Proliferation of HepG2 Cells.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 8, p. 4040, doi. 10.3390/ijms22084040

By:

Hasei, Shun;
Yamamotoya, Takeshi;
Nakatsu, Yusuke;
Ohata, Yukino;
Itoga, Shota;
Nonaka, Yuji;
Matsunaga, Yasuka;
Sakoda, Hideyuki;
Fujishiro, Midori;
Kushiyama, Akifumi;
Asano, Tomoichiro

Publication type:

Article

Xanthine Oxidase Inhibitor Febuxostat Exerts an Anti-Inflammatory Action and Protects against Diabetic Nephropathy Development in KK-Ay Obese Diabetic Mice.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 19, p. 4680, doi. 10.3390/ijms20194680

By:

Mizuno, Yu;
Yamamotoya, Takeshi;
Nakatsu, Yusuke;
Ueda, Koji;
Matsunaga, Yasuka;
Inoue, Masa-Ki;
Sakoda, Hideyuki;
Fujishiro, Midori;
Ono, Hiraku;
Kikuchi, Takako;
Takahashi, Masahiro;
Morii, Kenichi;
Sasaki, Kensuke;
Masaki, Takao;
Asano, Tomoichiro;
Kushiyama, Akifumi

Publication type:

Article

The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 3967, doi. 10.3390/ijms19123967

By:

Inoue, Masa-Ki;
Yamamotoya, Takeshi;
Nakatsu, Yusuke;
Ueda, Koji;
Inoue, Yuki;
Matsunaga, Yasuka;
Sakoda, Hideyuki;
Fujishiro, Midori;
Ono, Hiraku;
Morii, Kenichi;
Sasaki, Kensuke;
Masaki, Takao;
Suzuki, Yusuke;
Asano, Tomoichiro;
Kushiyama, Akifumi

Publication type:

Article

Roles of Gut-Derived Secretory Factors in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Their Possible Clinical Applications.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 10, p. 3064, doi. 10.3390/ijms19103064

By:

Okubo, Hirofumi;
Kushiyama, Akifumi;
Nakatsu, Yusuke;
Yamamotoya, Takeshi;
Matsunaga, Yasuka;
Fujishiro, Midori;
Sakoda, Hideyuki;
Ohno, Haruya;
Yoneda, Masayasu;
Asano, Tomoichiro

Publication type:

Article

The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 8, p. 1704, doi. 10.3390/ijms18081704

By:

Yusuke Nakatsu;
Hiroki Kokubo;
Batmunkh Bumdelger;
Masao Yoshizumi;
Takeshi Yamamotoya;
Yasuka Matsunaga;
Koji Ueda;
Yuki Inoue;
Masa-Ki Inoue;
Midori Fujishiro;
Akifumi Kushiyama;
Hiraku Ono;
Hideyuki Sakoda;
Tomoichiro Asano

Publication type:

Article

Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations.

Published in:

International Journal of Molecular Sciences, 2016, v. 17, n. 9, p. 1495, doi. 10.3390/ijms17091495

By:

Yusuke Nakatsu;
Yasuka Matsunaga;
Takeshi Yamamotoya;
Koji Ueda;
Yuki Inoue;
Keiichi Mori;
Hideyuki Sakoda;
Midori Fujishiro;
Hiraku Ono;
Akifumi Kushiyama;
Tomoichiro Asano

Publication type:

Article

Expression of Glucose Transporter Isoforms with Aging.

Published in:

Gerontology, 1992, v. 38, n. S1, p. 3, doi. 10.1159/000213355

By:

Oka, Yoshitomo;
Asano, Tomoichiro;
Lin, Jiann-Liang;
Tsukuda, Katsunori;
Katagiri, Hideki;
Ishihara, Hisamitsu;
Inukai, Kouichi;
Yazaki, Yoshio

Publication type:

Article

Valsartan restores inflammatory response by macrophages in adipose and hepatic tissues of LPS-infused mice.

Published in:

Adipocyte, 2013, v. 2, n. 1, p. 28, doi. 10.4161/adip.21837

By:

Iwashita, Misaki;
Nakatsu, Yusuke;
Sakoda, Hideyuki;
Fujishiro, Midori;
Kushiyama, Akifumi;
Fukushima, Toshiaki;
Kumamoto, Sonoko;
Shinjo, Takanori;
Kamata, Hideaki;
Nishimura, Fusanori;
Asano, Tomoichiro

Publication type:

Article

Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus.

Published in:

Diabetology & Metabolic Syndrome, 2015, v. 7, p. 1, doi. 10.1186/s13098-015-0102-8

By:

Shirong Qiang;
Yusuke Nakatsu;
Yasuyuki Seno;
Midori Fujishiro;
Hideyuki Sakoda;
Akifumi Kushiyama;
Keiichi Mori;
Yasuka Matsunaga;
Takeshi Yamamotoya;
Hideaki Kamata;
Tomoichiro Asano

Publication type:

Article

High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice.

Published in:

Diabetology & Metabolic Syndrome, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13098-015-0047-y

By:

Takanori Shinjo;
Yusuke Nakatsu;
Misaki Iwashita;
Tomomi Sano;
Hideyuki Sakoda;
Hisamitsu Ishihara;
Akifumi Kushiyama;
Midori Fujishiro;
Fusanori Nishimura;
Tomoichiro Asano

Publication type:

Article

Adipocyte-macrophage interaction may mediate LPS-induced low-grade inflammation: Potential link with metabolic complications.

Published in:

Innate Immunity, 2012, v. 18, n. 1, p. 164, doi. 10.1177/1753425910393370

By:

Nakarai, Hideo;
Yamashita, Akiko;
Nagayasu, Shintaro;
Iwashita, Misaki;
Kumamoto, Sonoko;
Ohyama, Hideki;
Hata, Masaki;
Soga, Yoshihiko;
Kushiyama, Akifumi;
Asano, Tomoichiro;
Abiko, Yoshimitsu;
Nishimura, Fusanori

Publication type:

Article

LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.

Published in:

Mediators of Inflammation, 2015, v. 2015, p. 1, doi. 10.1155/2015/125380

By:

Matsunaga, Yasuka;
Nakatsu, Yusuke;
Fukushima, Toshiaki;
Okubo, Hirofumi;
Iwashita, Misaki;
Sakoda, Hideyuki;
Fujishiro, Midori;
Yamamotoya, Takeshi;
Kushiyama, Akifumi;
Takahashi, Shin-ichiro;
Tsuchiya, Yoshihiro;
Kamata, Hideaki;
Tokunaga, Fuminori;
Iwai, Kazuhiro;
Asano, Tomoichiro

Publication type:

Article

Ccr7 null mice are protected against diet-induced obesity via Ucp1 upregulation and enhanced energy expenditure.

Published in:

Nutrition & Metabolism, 2019, v. 16, n. 1, p. N.PAG, doi. 10.1186/s12986-019-0372-5

By:

Sano, Tomomi;
Sanada, Taiki;
Sotomaru, Yusuke;
Shinjo, Takanori;
Iwashita, Misaki;
Yamashita, Akiko;
Fukuda, Takao;
Sanui, Terukazu;
Asano, Tomoichiro;
Kanematsu, Takashi;
Nishimura, Fusanori

Publication type:

Article

XAF1 overexpression exacerbates diabetes by promoting pancreatic β-cell apoptosis.

Published in:

Acta Diabetologica, 2022, v. 59, n. 10, p. 1275, doi. 10.1007/s00592-022-01930-y

By:

Nishimura, Yuki;
Iwashita, Misaki;
Hayashi, Masato;
Shinjo, Takanori;
Watanabe, Yukari;
Zeze, Tatsuro;
Yamashita, Akiko;
Fukuda, Takao;
Sanui, Terukazu;
Sano, Tomomi;
Asano, Tomoichiro;
Nishimura, Fusanori

Publication type:

Article

Extremely Early Onset of Ranitidine Action on Human Histamine H[sub 2] Receptors Expressed in HEK293 Cells.

Published in:

Digestion, 2003, v. 68, n. 2/3, p. 145, doi. 10.1159/000075349

By:

Fukushima, Yasushi;
Ishikawa, Takashi;
Saitoh, Toshihito;
Tateishi, Keisuke;
Ogihara, Takehide;
Fujishiro, Midori;
Shojima, Nobuhiro;
Honda, Miho;
Kushiyama, Akifumi;
Anai, Motonobu;
Sakoda, Hideyuki;
Ono, Hiraku;
Onishi, Yukiko;
Otsuka, Hiroko;
Katagiri, Hideki;
Nagai, Ryozo;
Omata, Masao;
Asano, Tomoichiro

Publication type:

Article

Potent and Long-Lasting Action of Lafutidine on the Human Histamine H[sub 2] Receptor.

Published in:

Digestion, 2001, v. 64, n. 3, p. 155, doi. 10.1159/000048856

By:

Fukushima, Yasushi;
Otsuka, Hiroko;
Ishikawa, Minako;
Asano, Tomoichiro;
Anai, Motonobu;
Katsube, Takao;
Ogawa, Kenji;
Kajiwara, Tetsuro;
Ohkawa, Shinichiro;
Ishikawa, Takashi;
Omata, Masao;
Saitoh, Toshihito

Publication type:

Article

Localization of the Histamine H[sub 2] Receptor, a Target for Antiulcer Drugs, in Gastric Parietal Cells.

Published in:

Digestion, 1999, v. 60, n. 6, p. 522, doi. 10.1159/000007701

By:

Fukushima, Yasushi;
Ohmachi, Yasushi;
Asano, Tomoichiro;
Nawano, Masao;
Funaki, Makoto;
Anai, Motonobu;
Ogihara, Takehide;
Inukai, Kouichi;
Onishi, Yukiko;
Sakoda, Hideyuki;
Saitoh, Toshihito;
Matsuhashi, Nobuyuki;
Yazaki, Yoshio;
Sugano, Kentaro

Publication type:

Article

Insulin receptor substrate-1 (IRS-1) forms a ribonucleoprotein complex associated with polysomes.

Published in:

FEBS Letters, 2013, v. 587, n. 15, p. 2319, doi. 10.1016/j.febslet.2013.05.066

By:

Ozoe, Atsufumi;
Sone, Meri;
Fukushima, Toshiaki;
Kataoka, Naoyuki;
Arai, Toshiya;
Chida, Kazuhiro;
Asano, Tomoichiro;
Hakuno, Fumihiko;
Takahashi, Shin-Ichiro

Publication type:

Article

The p85α Regulatory Subunit of Phosphoinositide 3-Kinase Potentiates c-Jun N-Terminal Kinase-Mediated Insulin Resistance.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 8, p. 5, doi. 10.1128/MCB.00079-07

By:

Taniguchi, Cullen M.;
Aleman, José O.;
Ueki, Kohjiro;
Ji Luo;
Asano, Tomoichiro;
Kaneto, Hideaki;
Stephanopoulos, Gregory;
Cantley, Lewis C.;
Kahn, C. Ronald

Publication type:

Article

Calpain 6 Is Involved in Microtubule Stabilization and Cytoskeletal Organization.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 7, p. 12, doi. 10.1128/MCB.00992-06

By:

Tonami, Kazuo;
Kurihara, Yukiko;
Aburatani, Hiroyuki;
Uchijima, Yasunobu;
Asano, Tomoichiro;
Kurihara, Hiroki

Publication type:

Article

A high-throughput screen for inhibitors of the prolyl isomerase, Pinl, identifies a seaweed polyphenol that reduces adipose cell differentiation.

Published in:

Bioscience, Biotechnology & Biochemistry, 2014, v. 78, n. 5, p. 832, doi. 10.1080/09168451.2014.905189

By:

Mori, Tadashi;
Hidaka, Masafumi;
Ikuji, Hiroko;
Yoshizawa, Ibuki;
Toyohara, Haruhiko;
Okuda, Tom;
Uchida, Chiyoko;
Asano, Tomoichiro;
Yotsu-Yamashita, Mari;
Uchida, Takafumi

Publication type:

Article

Par14 interacts with the androgen receptor, augmenting both its transcriptional activity and prostate cancer proliferation.

Published in:

Cancer Medicine, 2023, v. 12, n. 7, p. 8464, doi. 10.1002/cam4.5587

By:

Naito, Miki;
Ikeda, Kenichiro;
Aoyama, Shunya;
Kanamoto, Mayu;
Akasaka, Yasuyuki;
Kido, Yuri;
Nakanishi, Mikako;
Kanna, Machi;
Yamamotoya, Takeshi;
Matsubara, Akio;
Hinata, Nobuyuki;
Asano, Tomoichiro;
Nakatsu, Yusuke

Publication type:

Article

A hepatic amino acid/mTOR/S6K-dependent signalling pathway modulates systemic lipid metabolism via neuronal signals.

Published in:

Nature Communications, 2015, v. 6, n. 8, p. 7940, doi. 10.1038/ncomms8940

By:

Uno, Kenji;
Yamada, Tetsuya;
Ishigaki, Yasushi;
Imai, Junta;
Hasegawa, Yutaka;
Sawada, Shojiro;
Kaneko, Keizo;
Ono, Hiraku;
Asano, Tomoichiro;
Oka, Yoshitomo;
Katagiri, Hideki

Publication type:

Article

Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity.

Published in:

Nature Communications, 2015, v. 6, n. 4, p. 6780, doi. 10.1038/ncomms7780

By:

Fukushima, Toshiaki;
Yoshihara, Hidehito;
Furuta, Haruka;
Kamei, Hiroyasu;
Hakuno, Fumihiko;
Luan, Jing;
Duan, Cunming;
Saeki, Yasushi;
Tanaka, Keiji;
Iemura, Shun-Ichiro;
Natsume, Tohru;
Chida, Kazuhiro;
Nakatsu, Yusuke;
Kamata, Hideaki;
Asano, Tomoichiro;
Takahashi, Shin-Ichiro

Publication type:

Article

Neuronal signals regulate obesity induced β-cell proliferation by Fox M1 dependent mechanism.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01869-7

By:

Junpei Yamamoto;
Imai, Junta;
Tomohito Izumi;
Hironori Takahashi;
Yohei Kawana;
Kei Takahashi;
Shinjiro Kodama;
Keizo Kaneko;
Junhong Gao;
Kenji Uno;
Shojiro Sawada;
Tomoichiro Asano;
Kalinichenko, Vladimir V.;
Susaki, Etsuo A.;
Makoto Kanzaki;
Ueda, Hiroki R.;
Yasushi Ishigaki;
Tetsuya Yamada;
Hideki Katagiri

Publication type:

Article

Insulin Resistance-Inducible RELM (Resistin Like Molecule) Beta also Involves Atherosclerosis with Directly Affecting Endothelial Function.

Published in:

Diabetes, 2007, v. 56, p. A669

By:

Kushiyama, Akifumi;
Sakoda, Hideyuki;
Fujishiro, Midori;
Anai, Motonobu;
Inukai, Kouichi;
Ogihara, Takehide;
Kikuchi, Masatoshi;
Asano, Tomoichiro

Publication type:

Article

Hypothalamic S6 Kinase 1 Is Responsible for Short-Term Diet-Induced Hepatic Insulin Resistance.

Published in:

Diabetes, 2007, v. 56, p. A407

By:

Ono, Hiraku;
Pocai, Alessandro;
Wang, Yuhua;
Sakoda, Hideyuki;
Asano, Tomoichiro;
Rossetti, Luciano

Publication type:

Article

Hepatic Overexpression of Dominant Negative Form of mTOR Enhances Akt Phosphorylation and Restores Insulin Resistance in K/KAy Mice.

Published in:

Diabetes, 2007, v. 56, p. A35

By:

Koketsu, Yuko;
Sakoda, Hideyuki;
Fujishiro, Midori;
Kushiyama, Aki-Fumi;
Kikuchi, Takako;
Fukuda, Takeshi;
Asano, Tomoichiro

Publication type:

Article

Dissipating excess energy stored in the liver is a potential treatment strategy for diabetes associated with obesity.

Published in:

2005

By:

Ishigaki, Yasushi;
Katagiri, Hideki;
Yamada, Tetsuya;
Ogihara, Takehide;
Imai, Junta;
Uno, Kenji;
Hasegawa, Yutaka;
Gao, Junhong;
Ishihara, Hisamitsu;
Shimosegawa, Tooru;
Sakoda, Hideyuki;
Asano, Tomoichiro;
Oka, Yoshitomo

Publication type:

journal article

Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement.

Published in:

2003

By:

Ono, Hiraku;
Sakoda, Hideyuki;
Onishi, Yukiko;
Anai, Motonobu;
Kikuchi, Masatoshi;
Shimano, Hitoshi;
Yamada, Nobuhiro;
Katagiri, Hideki;
Ogihara, Takehide;
Oka, Yoshitomo;
Yahagi, Naoya;
Fujishiro, Midori;
Fukushima, Yasushi;
Abe, Miho;
Shojima, Nobuhiro;
Asano, Tomoichiro;
Viana, Amelia Y.I.

Publication type:

journal article

Humoral Regulation of Resistin Expression in 2T2-L1 and Mouse Adipose Cells.

Published in:

Diabetes, 2002, v. 51, n. 6, p. 1737, doi. 10.2337/diabetes.51.6.1737

By:

Shojima, Nobuhiro;
Sakoda, Hideyuki;
Ogihara, Takehide;
Fujishiro, Midori;
Katagiri, Hideki;
Anai, Motonobu;
Onishi, Yukiko;
Ono, Hiraku;
Inukai, Kouichi;
Abe, Miho;
Fukushima, Yasushi;
Kikuchi, Masatoshi;
Oka, Yoshitomo;
Asano, Tomoichiro

Publication type:

Article

Insulin resistance with enhanced insulin signaling in high-salt diet-fed rats.

Published in:

2001

By:

Ogihara, Takehide;
Asano, Tomoichiro;
Ogihara, T;
Asano, T;
Ando, K;
Chiba, Y;
Sekine, N;
Sakoda, H;
Anai, M;
Onishi, Y;
Fujishiro, M;
Ono, H;
Shojima, N;
Inukai, K;
Fukushima, Y;
Kikuchi, M;
Fujita, T

Publication type:

journal article