Works by Arnaout, M. Amin

Results: 25

Platelet integrin αIIbβ3 plays a key role in a venous thrombogenesis mouse model.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52869-3

By:

Adair, Brian D.;
Field, Conroy O.;
Alonso, José L.;
Xiong, Jian-Ping;
Deng, Shi-Xian;
Ahn, Hyun Sook;
Mashin, Eivgeni;
Clish, Clary B.;
van Agthoven, Johannes;
Yeager, Mark;
Guo, Youzhong;
Tess, David A.;
Landry, Donald W.;
Poncz, Mortimer;
Arnaout, M. Amin

Publication type:

Article

Stress Hematopoiesis Is Regulated by the Krüppel-Like Transcription Factor ZBP-89.

Published in:

Stem Cells, 2014, v. 32, n. 3, p. 791, doi. 10.1002/stem.1598

By:

L i, Xiangen;
Romain, Rachael D.;
Park, Dongsu;
Scadden, David T.;
Merchant, Juanita L.;
Arnaout, M. Amin

Publication type:

Article

Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment.

Published in:

Journal of Cell Biology, 2009, v. 186, n. 4, p. 589, doi. 10.1083/jcb.200905085

By:

Xiong, Jian-Ping;
Mahalingham, Bhuvaneshwari;
Alonso, Jose Luis;
Borrelli, Laura Ann;
Rui, Xianliang;
Anand, Saurabh;
Hyman, Bradley T.;
Rysiok, Thomas;
Müller-Pompalla, Dirk;
Goodman, Simon L.;
Arnaout, M. Amin

Publication type:

Article

Three-dimensional EM structure of the ectodomain of integrin αV&beta3 in a complex with fibronectin.

Published in:

Journal of Cell Biology, 2005, v. 168, n. 7, p. 1109, doi. 10.1083/jcb.200410068

By:

Adair, Brian D.;
Xiong, Jian-Ping;
Maddock, Catherine;
Goodman, Simon L.;
Arnaout, M. Amin;
Yeager, Mark

Publication type:

Article

A microfluidic renal proximal tubule with active reabsorptive function.

Published in:

PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0184330

By:

Vedula, Else M.;
Alonso, José Luis;
Arnaout, M. Amin;
Charest, Joseph L.

Publication type:

Article

INTEGRINS: A BEDSIDE TO BENCH TO BEDSIDE STORY.

Published in:

Transactions of the American Clinical & Climatological Association, 2023, v. 133, p. 34

By:

ARNAOUT, M. AMIN

Publication type:

Article

Integrin structure: new twists and turns in dynamic cell adhesion.

Published in:

Immunological Reviews, 2002, v. 186, n. 1, p. 125, doi. 10.1034/j.1600-065X.2002.18612.x

By:

Arnaout, M. Amin

Publication type:

Article

CD43 gene expression is mediated by a nuclear factor which binds pyrimidine-rich single-stranded DNA.

Published in:

Nucleic Acids Research, 2000, v. 28, n. 11, p. 2256, doi. 10.1093/nar/28.11.2256

By:

Farokhzad, Omid C.;
Teodoridis, Jens M.;
Park, Heiyoung;
Arnaout, M. Amin;
Shelley, Carl S.

Publication type:

Article

Cryo-EM structures of full-length integrin αIIbβ3 in native lipids.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39763-0

By:

Adair, Brian D.;
Xiong, Jian-Ping;
Yeager, Mark;
Arnaout, M. Amin

Publication type:

Article

Prophylactic orthosteric inhibition of leukocyte integrin CD11b/CD18 prevents long-term fibrotic kidney failure in cynomolgus monkeys.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 13899, doi. 10.1038/ncomms13899

By:

Dehnadi, Abbas;
Benedict Cosimi, A.;
Neal Smith, Rex;
Li, Xiangen;
Alonso, José L.;
Means, Terry K.;
Arnaout, M. Amin

Publication type:

Article

The vasculopathy of autosomal dominant polycystic kidney disease: Insights from animal models.

Published in:

Kidney International, 2000, v. 58, n. 6, p. 2599, doi. 10.1046/j.1523-1755.2000.00446.x

By:

Arnaout, M. Amin

Publication type:

Article

Emerging paradigms of integrin ligand binding and activation.

Published in:

Kidney International, 1997, v. 51, n. 5, p. 1454, doi. 10.1038/ki.1997.199

By:

Sugimori, Takashi;
Griffith, Diana L.;
Arnaout, M. Amin

Publication type:

Article

A case management model to improve hemodialysis outpatient outcomes.

Published in:

Hemodialysis International, 2007, v. 11, n. 2, p. 247, doi. 10.1111/j.1542-4758.2007.00176.x

By:

STEELE, David J. R.;
HAMILTON, Emel;
ARNAOUT, M. Amin

Publication type:

Article

The Integrin Receptors: From Discovery to Structure to Medicines.

Published in:

Immunological Reviews, 2025, v. 329, n. 1, p. 1, doi. 10.1111/imr.13433

By:

Arnaout, M. Amin

Publication type:

Article

LFA-1 β-chain synthesis and degradation in patients with leukocyte-adhesive proteins deficiency.

Published in:

European Journal of Immunology, 1987, v. 17, n. 3, p. 417, doi. 10.1002/eji.1830170318

By:

Dimanche, Marie-Therèse;
Le Deist, Franç;
Fischer, Alain;
Arnaout, M. Amin;
Griscelli, Claude;
Lisowska-Grospierre, Barbara

Publication type:

Article

pl50/95, Third member of the LFA-1/CR.

Published in:

European Journal of Immunology, 1985, v. 15, n. 7, p. 713, doi. 10.1002/eji.1830150714

By:

Lanier, Lewis L.;
Amin Arnaout, M.;
Schwarting, Roland;
Warner, Noel L.;
Ross, Gordon D.

Publication type:

Article

Role of human factor I and C3b receptor in the cleavage of surface-bound C3bi molecules.

Published in:

European Journal of Immunology, 1983, v. 13, n. 6, p. 465, doi. 10.1002/eji.1830130607

By:

Medicus, Rudolf G.;
Melamed, Julian;
Arnaout, M. Amin

Publication type:

Article

Talin1 is required for cardiac Z-disk stabilization and endothelial integrity in zebrafish.

Published in:

FASEB Journal, 2015, v. 29, n. 12, p. 4989, doi. 10.1096/fj.15-273409

By:

Qing Wu;
Jiaojiao Zhang;
Wonshill Koh;
Qingming Yu;
Xiaojun Zhu;
Amsterdam, Adam;
Davis, George E.;
Arnaout, M. Amin;
Jing-Wei Xiong

Publication type:

Article

A synthetic eicosanoid LX-mimetic unravels host-donor interactions in allogeneic BMT-induced GvHD to reveal an early protective role for host neutrophils.

Published in:

FASEB Journal, 2005, v. 19, n. 2, p. 203, doi. 10.1096/fj.04-2565com

By:

Devchand, Pallavi R.;
Schmidt, Birgitta A.;
Primo, Valeria C.;
Qing-yin Zhang;
Arnaout, M. Amin;
Serhan, Charles N.;
Nikolic, Boris

Publication type:

Article

Structural basis for pure antagonism of integrin α<sub>V</sub>β<sub>3</sub> by a high-affinity form of fibronectin.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 383, doi. 10.1038/nsmb.2797

By:

Van Agthoven, Johannes F;
Xiong, Jian-Ping;
Alonso, José Luis;
Rui, Xianliang;
Adair, Brian D;
Goodman, Simon L;
Arnaout, M Amin

Publication type:

Article

Negative Regulation of TGFβ Signaling by Stem Cell Antigen-1 Protects against Ischemic Acute Kidney Injury.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0129561

By:

Camarata, Troy D.;
Weaver, Grant C.;
Vasilyev, Alexandr;
Arnaout, M. Amin

Publication type:

Article

Collective Epithelial Migration Drives Kidney Repair after Acute Injury.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0101304

By:

Palmyre, Aurélien;
Lee, Jeongeun;
Ryklin, Gennadiy;
Camarata, Troy;
Selig, Martin K.;
Duchemin, Anne-Laure;
Nowak, Paul;
Arnaout, M. Amin;
Drummond, Iain A.;
Vasilyev, Aleksandr

Publication type:

Article

EM Structure of the Ectodomain of Integrin CD11b/CD18 and Localization of Its Ligand-Binding Site Relative to the Plasma Membrane.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0057951

By:

Adair, Brian D.;
Xiong, Jian-Ping;
Alonso, José Luis;
Hyman, Bradley T.;
Arnaout, M. Amin

Publication type:

Article

Relative contribution of the leukocyte molecules MO1, LFA-1, and p150,95 (LeuM5) in adhesion of granulocytes and monocytes to vascular endothelium is tissue- and stimulus-specific.

Published in:

Journal of Cellular Physiology, 1988, v. 137, n. 2, p. 305, doi. 10.1002/jcp.1041370214

By:

Arnaout, M. Amin;
Lanier, Lewis L.;
Faller, Douglas V.

Publication type:

Article

Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-13928-2

By:

Adair, Brian D.;
Alonso, José L.;
van Agthoven, Johannes;
Hayes, Vincent;
Ahn, Hyun Sook;
Yu, I-Shing;
Lin, Shu-Wha;
Xiong, Jian-Ping;
Poncz, Mortimer;
Arnaout, M. Amin

Publication type:

Article