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Gastric cancer in the era of molecularly targeted agents: current drug development strategies.
- Published in:
- Journal of Cancer Research & Clinical Oncology, 2009, v. 135, n. 7, p. 855, doi. 10.1007/s00432-009-0583-7
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- Publication type:
- Article
Pharmacokinetic Interaction Between the MEK1/MEK2 Inhibitor Trametinib and Oral Contraceptives Containing Norethindrone and Ethinyl Estradiol in Female Patients With Solid Tumors.
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- Clinical Pharmacology in Drug Development, 2022, v. 11, n. 5, p. 585, doi. 10.1002/cpdd.1052
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- Publication type:
- Article
Research biopsies in the context of early phase oncology studies: clinical and ethical considerations.
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- Oncology Reviews, 2013, v. 7, n. 1, p. 34, doi. 10.4081/oncol.2013.e5
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- Publication type:
- Article
Enduring efficacy and tolerability of daratumumab in combination with lenalidomide and dexamethasone in patients with relapsed or relapsed/refractory multiple myeloma (GEN503): final results of an open‐label, phase 1/2 study.
- Published in:
- British Journal of Haematology, 2019, v. 186, n. 3, p. e35, doi. 10.1111/bjh.15879
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- Publication type:
- Article
A first-in-human phase I study of TAS0728, an oral covalent binding inhibitor of HER2, in patients with advanced solid tumors with HER2 or HER3 aberrations.
- Published in:
- Investigational New Drugs, 2021, v. 39, n. 5, p. 1324, doi. 10.1007/s10637-021-01104-7
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- Publication type:
- Article
Phase I study of continuous olaparib capsule dosing in combination with carboplatin and/or paclitaxel (Part 1).
- Published in:
- Investigational New Drugs, 2020, v. 38, n. 4, p. 1117, doi. 10.1007/s10637-019-00856-7
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- Publication type:
- Article
Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2).
- Published in:
- Investigational New Drugs, 2020, v. 38, n. 4, p. 1096, doi. 10.1007/s10637-019-00857-6
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- Publication type:
- Article
Dabrafenib and trametinib activity in a patient with BRAF V600E mutated and microsatellite instability high (MSI.H) metastatic endometrial cancer.
- Published in:
- Experimental Hematology & Oncology, 2017, v. 6, p. 1, doi. 10.1186/s40164-016-0061-2
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- Publication type:
- Article
Clinical Impact of Checkpoint Inhibitors as Novel Cancer Therapies.
- Published in:
- 2014
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- Publication type:
- Journal Article
Combination Molecularly Targeted Drug Therapy in Metastatic Melanoma: Progress to Date.
- Published in:
- 2013
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- Publication type:
- Journal Article
Ezabenlimab (BI 754091), an anti-PD-1 antibody, in patients with advanced solid tumours.
- Published in:
- Cancer Immunology, Immunotherapy, 2024, v. 73, n. 5, p. 1, doi. 10.1007/s00262-024-03654-0
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- Publication type:
- Article
Phase 1b study of berzosertib and cisplatin in patients with advanced triple-negative breast cancer.
- Published in:
- NPJ Breast Cancer, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41523-022-00406-0
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- Publication type:
- Article
Evaluation of the effect of dabrafenib and metabolites on QTc interval in patients with <italic>BRAF</italic> V600–mutant tumours.
- Published in:
- British Journal of Clinical Pharmacology, 2018, v. 84, n. 4, p. 764, doi. 10.1111/bcp.13488
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- Publication type:
- Article
Selective RET Inhibitors (SRIs) in Cancer: A Journey from Multi-Kinase Inhibitors to the Next Generation of SRIs.
- Published in:
- Cancers, 2024, v. 16, n. 1, p. 31, doi. 10.3390/cancers16010031
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- Publication type:
- Article
Untailored vs. Gender- and Body-Mass-Index-Tailored Skeletal Muscle Mass Index (SMI) to Assess Sarcopenia in Advanced Head and Neck Squamous Cell Carcinoma (HNSCC).
- Published in:
- Cancers, 2023, v. 15, n. 19, p. 4716, doi. 10.3390/cancers15194716
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- Publication type:
- Article
Irinotecan- vs. Oxaliplatin-Based Doublets in KRAS G12C -Mutated Metastatic Colorectal Cancer—A Multicentre Propensity-Score-Matched Retrospective Analysis.
- Published in:
- Cancers, 2023, v. 15, n. 11, p. 3064, doi. 10.3390/cancers15113064
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- Publication type:
- Article
Results from a Phase 1b/2 Study of Ibrutinib Combination Therapy in Advanced Urothelial Carcinoma.
- Published in:
- Cancers, 2023, v. 15, n. 11, p. 2978, doi. 10.3390/cancers15112978
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- Publication type:
- Article
Immune Response in Vitamin D Deficient Metastatic Colorectal Cancer Patients: A Player That Should Be Considered for Targeted Vitamin D Supplementation.
- Published in:
- Cancers, 2022, v. 14, n. 11, p. 2594, doi. 10.3390/cancers14112594
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- Publication type:
- Article
Ramucirumab in Combination with Pembrolizumab in Treatment-Naïve Advanced Gastric or GEJ Adenocarcinoma: Safety and Antitumor Activity from the Phase 1a/b JVDF Trial.
- Published in:
- Cancers, 2020, v. 12, n. 10, p. 2985, doi. 10.3390/cancers12102985
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- Publication type:
- Article
Recent Progress in the Systemic Treatment of Advanced/Metastatic Cholangiocarcinoma.
- Published in:
- Cancers, 2020, v. 12, n. 9, p. 2599, doi. 10.3390/cancers12092599
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- Publication type:
- Article
Biomarkers in Advanced Colorectal Cancer: Challenges in Translating Clinical Research into Practice.
- Published in:
- Cancers, 2011, v. 3, n. 2, p. 1844, doi. 10.3390/cancers3021844
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- Publication type:
- Article
Ibrutinib combination therapy for advanced gastrointestinal and genitourinary tumours: results from a phase 1b/2 study.
- Published in:
- BMC Cancer, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12885-023-11539-1
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- Publication type:
- Article
Avelumab, an anti-PD-L1 antibody, in patients with locally advanced or metastatic breast cancer: a phase 1b JAVELIN Solid Tumor study.
- Published in:
- Breast Cancer Research & Treatment, 2018, v. 167, n. 3, p. 671, doi. 10.1007/s10549-017-4537-5
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- Publication type:
- Article
Antitumor Activity and Safety of Dostarlimab Monotherapy in Patients With Mismatch Repair Deficient Solid Tumors: A Nonrandomized Controlled Trial.
- Published in:
- JAMA Network Open, 2023, v. 6, n. 11, p. e2341165, doi. 10.1001/jamanetworkopen.2023.41165
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- Publication type:
- Article
Phase 1b study to assess the safety, tolerability, and clinical activity of pamiparib in combination with temozolomide in patients with locally advanced or metastatic solid tumors.
- Published in:
- Cancer Medicine, 2024, v. 13, n. 13, p. 1, doi. 10.1002/cam4.7385
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- Publication type:
- Article
Dynamics of Neutrophils-to-Lymphocyte Ratio Predict Outcomes of PD-1/PD-L1 Blockade.
- Published in:
- BioMed Research International, 2017, v. 2017, p. 1, doi. 10.1155/2017/1506824
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- Publication type:
- Article
A study of the focal adhesion kinase inhibitor GSK2256098 in patients with recurrent glioblastoma with evaluation of tumor penetration of [11C]GSK2256098.
- Published in:
- Neuro-Oncology, 2018, v. 20, n. 12, p. 1634, doi. 10.1093/neuonc/noy078
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- Publication type:
- Article
The potential for BRAF V600 inhibitors in advanced cutaneous melanoma: rationale and latest evidence.
- Published in:
- Therapeutic Advances in Medical Oncology, 2012, v. 4, n. 2, p. 61, doi. 10.1177/1758834011432949
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- Publication type:
- Article
A phase 1, open-label, dose-escalation trial of oral TSR-011 in patients with advanced solid tumours and lymphomas.
- Published in:
- 2019
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- Publication type:
- journal article
A phase Ib dose-finding, pharmacokinetic study of the focal adhesion kinase inhibitor GSK2256098 and trametinib in patients with advanced solid tumours.
- Published in:
- 2019
- By:
- Publication type:
- journal article
SELECT-3: a phase I study of selumetinib in combination with platinum-doublet chemotherapy for advanced NSCLC in the first-line setting.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Prognostic Value of Reduced SMAD4 Expression in Patients With Metastatic Colorectal Cancer Under Oxaliplatin-Containing Chemotherapy: A Translational Study of the AIO Colorectal Study Group.
- Published in:
- Clinical Colorectal Cancer, 2011, v. 10, n. 1, p. 24, doi. 10.3816/CCC.2011.n.003
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- Publication type:
- Article
BRAF/MEK inhibitors for BRAF V600E-mutant cancers in non-approved setting: a case series.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2021, v. 87, n. 3, p. 437, doi. 10.1007/s00280-021-04234-0
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- Publication type:
- Article
Phase 1 study of cardiac safety of TAS-102 in patients with advanced solid tumors.
- Published in:
- 2016
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- Publication type:
- journal article
Immunotherapy for bladder cancer: rediscovering an old friend.
- Published in:
- BJU International, 2016, v. 117, n. 5, p. 721, doi. 10.1111/bju.13330
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- Publication type:
- Article
Novel Treatments for Metastatic Cutaneous Melanoma and the Management of Emergent Toxicities.
- Published in:
- Clinical Medicine Insights: Oncology, 2012, n. 6, p. 53, doi. 10.4137/CMO.S5855
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- Publication type:
- Article
Novel Treatments for Metastatic Cutaneous Melanoma and the Management of Emergent Toxicities.
- Published in:
- Clinical Medicine Insights: Oncology, 2012, n. 6, p. 53, doi. 10.4137/CMO.S5855
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- Publication type:
- Article
Evaluation of CYP3A-Mediated Drug-Drug Interactions With Romidepsin in Patients With Advanced Cancer.
- Published in:
- Journal of Clinical Pharmacology, 2015, v. 55, n. 12, p. 1378, doi. 10.1002/jcph.560
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- Publication type:
- Article
Assessment of the drug interaction potential and single- and repeat-dose pharmacokinetics of the BRAF inhibitor dabrafenib.
- Published in:
- Journal of Clinical Pharmacology, 2015, v. 55, n. 4, p. 392, doi. 10.1002/jcph.437
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- Publication type:
- Article
HIF2α, Hepcidin and their crosstalk as tumour-promoting signalling.
- Published in:
- British Journal of Cancer, 2023, v. 129, n. 2, p. 222, doi. 10.1038/s41416-023-02266-2
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- Publication type:
- Article
Trifluridine/tipiracil in patients with metastatic gastroesophageal junction cancer: a subgroup analysis from the phase 3 TAGS study.
- Published in:
- Gastric Cancer, 2021, v. 24, n. 4, p. 970, doi. 10.1007/s10120-021-01156-x
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- Publication type:
- Article
Health-related quality of life associated with trifluridine/tipiracil in heavily pretreated metastatic gastric cancer: results from TAGS.
- Published in:
- Gastric Cancer, 2020, v. 23, n. 4, p. 689, doi. 10.1007/s10120-020-01053-9
- By:
- Publication type:
- Article
Mammographic Breast Density and Urbanization: Interactions with BMI, Environmental, Lifestyle, and Other Patient Factors.
- Published in:
- Diagnostics (2075-4418), 2020, v. 10, n. 6, p. 418, doi. 10.3390/diagnostics10060418
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- Publication type:
- Article
Complexity of FGFR signalling in metastatic urothelial cancer.
- Published in:
- Journal of Hematology & Oncology, 2015, v. 8, p. 1, doi. 10.1186/s13045-015-0221-6
- By:
- Publication type:
- Article
Gastric Inflammatory Prognostic Index (GIPI) in Patients with Metastatic Gastro-Esophageal Junction/Gastric Cancer Treated with PD-1/PD-L1 Immune Checkpoint Inhibitors.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Reporting time-to-event endpoints and response rates in 4 decades of randomized controlled trials in advanced colorectal cancer.
- Published in:
- Cancer (0008543X), 2011, v. 117, n. 4, p. 832, doi. 10.1002/cncr.25636
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- Publication type:
- Article
Enumeration and Molecular Characterisation of Circulating Tumour Cells in Endometrial Cancer.
- Published in:
- Oncology, 2016, v. 91, n. 1, p. 48, doi. 10.1159/000445999
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- Publication type:
- Article
Patients' Perceptions of Research Biopsies in Phase I Oncology Trials.
- Published in:
- Oncology, 2015, v. 88, n. 2, p. 95, doi. 10.1159/000368161
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- Publication type:
- Article
Clinical Benefit of New Targeted Agents in Phase I Trials in Patients with Advanced Colorectal Cancer.
- Published in:
- Oncology, 2009, v. 76, n. 3, p. 151, doi. 10.1159/000195884
- By:
- Publication type:
- Article
Signal pathways and precision therapy of small-cell lung cancer.
- Published in:
- Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01013-y
- By:
- Publication type:
- Article