Works by Arenz, Christoph

Results: 58

Monitoring Dicer‐Mediated miRNA‐21 Maturation and Ago2 Loading by a Dual‐Colour FIT PNA Probe Set.

Published in:

ChemBioChem, 2020, v. 21, n. 17, p. 2527, doi. 10.1002/cbic.202000173

By:

Loibl, Natalia;
Arenz, Christoph;
Seitz, Oliver

Publication type:

Article

A Fast and Easy Method for Specific Detection of Circular RNA by Rolling‐Circle Amplification.

Published in:

ChemBioChem, 2020, v. 21, n. 6, p. 793, doi. 10.1002/cbic.201900514

By:

Boss, Marcel;
Arenz, Christoph

Publication type:

Article

A Rapid and Versatile Assay for Ago2-Mediated Cleavage by Using Branched Rolling Circle Amplification.

Published in:

ChemBioChem, 2016, v. 17, n. 4, p. 304, doi. 10.1002/cbic.201500537

By:

Hesse, Marlen;
Arenz, Christoph

Publication type:

Article

A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones.

Published in:

Angewandte Chemie, 2010, v. 122, n. 21, p. 3748, doi. 10.1002/ange.200906555

By:

Wetzel, Stefan;
Wilk, Wolfram;
Chammaa, Samy;
Sperl, Bianca;
Roth, Anke G.;
Yektaoglu, Aybike;
Renner, Steffen;
Berg, Thorsten;
Arenz, Christoph;
Giannis, Athanassios;
Oprea, Tudor I.;
Rauh, Daniel;
Kaiser, Markus;
Waldmann, Herbert

Publication type:

Article

MicroRNAs – zukünftige Wirkstoff-Targets?Der Autor dankt dem Innovationsfonds der Humboldt-Universität zu Berlin und dem Fonds der Chemischen Industrie für finanzielle Unterstützung.

Published in:

Angewandte Chemie, 2006, v. 118, n. 31, p. 5170, doi. 10.1002/ange.200601537

By:

Christoph Arenz

Publication type:

Article

Trendbericht Organische Chemie 2017.

Published in:

Nachrichten aus der Chemie, 2018, v. 66, n. 3, p. 249, doi. 10.1002/nadc.20184072148

By:

Straub, Bernd;
Andexer, Jennifer N.;
Arenz, Christoph;
Beifuss, Uwe;
Beuerle, Florian;
Brasholz, Malte;
Breinbauer, Rolf;
Ditrich, Klaus;
Ernst, Martin;
Gulder, Tobias A. M.;
Kordes, Markus;
Krueger, Anke;
Lehmann, Matthias;
Lindel, Thomas;
Lüdeke, Steffen;
Luy, Burkhard;
Meier, Michael A. R.;
Mück‐Lichtenfeld, Christian;
Muhle‐Goll, Claudia;
Narine, Arun

Publication type:

Article

Organische Chemie 2016.

Published in:

Nachrichten aus der Chemie, 2017, v. 65, n. 3, p. 266, doi. 10.1002/nadc.20174059831

By:

Straub, Bernd F.;
Andexer, Jennifer;
Arenz, Christoph;
Beifuss, Uwe;
Beuerle, Florian;
Brasholz, Malte;
Breinbauer, Rolf;
Ditrich, Klaus;
Gulder, Tobias A. M.;
Hüttel, Wolfgang;
Kordes, Markus;
Krueger, Anke;
Lehmann, Matthias;
Lindel, Thomas;
Luy, Burkhard;
Meier, Michael A. R.;
Mück‐Lichtenfeld, Christian;
Muhle‐Goll, Claudia;
Müller, Thomas J. J.;
Narine, Arun

Publication type:

Article

Oligonukleotide.

Published in:

Nachrichten aus der Chemie, 2015, v. 63, n. 3, p. 296

By:

Arenz, Christoph

Publication type:

Article

Potent Inhibition of Acid Ceramidase by Novel B-13 Analogues.

Published in:

Journal of Lipids, 2011, p. 1, doi. 10.1155/2011/971618

By:

Proksch, Denny;
Klein, Jan Jasper;
Arenz, Christoph

Publication type:

Article

Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases**.

Published in:

Angewandte Chemie, 2022, v. 134, n. 2, p. 1, doi. 10.1002/ange.202109967

By:

Healey, Robert D.;
Saied, Essa M.;
Cong, Xiaojing;
Karsai, Gergely;
Gabellier, Ludovic;
Saint‐Paul, Julie;
Del Nero, Elise;
Jeannot, Sylvain;
Drapeau, Marion;
Fontanel, Simon;
Maurel, Damien;
Basu, Shibom;
Leyrat, Cedric;
Golebiowski, Jérôme;
Bossis, Guillaume;
Bechara, Cherine;
Hornemann, Thorsten;
Arenz, Christoph;
Granier, Sebastien

Publication type:

Article

Innentitelbild: Unterscheidung von isomeren Sphingolipiden mittels kryogener Infrarotspektroskopie (Angew. Chem. 32/2020).

Published in:

Angewandte Chemie, 2020, v. 132, n. 32, p. 13226, doi. 10.1002/ange.202007701

By:

Kirschbaum, Carla;
Saied, Essa M.;
Greis, Kim;
Mucha, Eike;
Gewinner, Sandy;
Schöllkopf, Wieland;
Meijer, Gerard;
Helden, Gert;
Poad, Berwyck L. J.;
Blanksby, Stephen J.;
Arenz, Christoph;
Pagel, Kevin

Publication type:

Article

Unterscheidung von isomeren Sphingolipiden mittels kryogener Infrarotspektroskopie.

Published in:

Angewandte Chemie, 2020, v. 132, n. 32, p. 13740, doi. 10.1002/ange.202002459

By:

Kirschbaum, Carla;
Saied, Essa M.;
Greis, Kim;
Mucha, Eike;
Gewinner, Sandy;
Schöllkopf, Wieland;
Meijer, Gerard;
Helden, Gert;
Poad, Berwyck L. J.;
Blanksby, Stephen J.;
Arenz, Christoph;
Pagel, Kevin

Publication type:

Article

Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor.

Published in:

Angewandte Chemie, 2020, v. 132, n. 14, p. 5770, doi. 10.1002/ange.201913712

By:

Laraia, Luca;
Garivet, Guillaume;
Foley, Daniel J.;
Kaiser, Nadine;
Müller, Sebastian;
Zinken, Sarah;
Pinkert, Thomas;
Wilke, Julian;
Corkery, Dale;
Pahl, Axel;
Sievers, Sonja;
Janning, Petra;
Arenz, Christoph;
Wu, Yaowen;
Rodriguez, Raphaël;
Waldmann, Herbert

Publication type:

Article

MicroRNA-145-targeted drug and its preventive effect on pulmonary arterial hypertension (patent WO2012153135 A1).

Published in:

Expert Opinion on Therapeutic Patents, 2015, v. 25, n. 6, p. 723, doi. 10.1517/13543776.2015.1025751

By:

Ogorodnikova, Natalia;
Arenz, Christoph

Publication type:

Article

Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein.

Published in:

Biological Chemistry, 2007, v. 388, n. 6, p. 617, doi. 10.1515/BC.2007.063

By:

Babalola, Jonathan O.;
Wendeler, Michaela;
Breiden, Bernadette;
Arenz, Christoph;
Schwarzmann, Guenter;
Locatelli-Hoops, Silvia;
Sandhoff, Konrad

Publication type:

Article

Five‐, Four‐ and Three‐Dentate Europium Chelates for Anion Sensing and Their Applicability to Enzymatic Dephosphorylation Reactions.

Published in:

ChemistrySelect, 2018, v. 3, n. 44, p. 12430, doi. 10.1002/slct.201803287

By:

Mohamed, Zainelabdeen. H.;
Soukka, Tero;
Arenz, Christoph;
Schäferling, Michael

Publication type:

Article

A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of γ-Pyrones.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 21, p. 3666, doi. 10.1002/anie.200906555

By:

Wetzel, Stefan;
Wilk, Wolfram;
Chammaa, Samy;
Sperl, Bianca;
Roth, Anke G.;
Yektaoglu, Aybike;
Renner, Steffen;
Berg, Thorsten;
Arenz, Christoph;
Giannis, Athanassios;
Oprea, Tudor I.;
Rauh, Daniel;
Kaiser, Markus;
Waldmann, Herbert

Publication type:

Article

Potent and Selective Inhibition of Acid Sphingomyelinase by Bisphosphonates.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 41, p. 7560, doi. 10.1002/anie.200903288

By:

Roth, Anke G.;
Drescher, Daniela;
Yang, Yang;
Redmer, Susanne;
Uhlig, Stefan;
Arenz, Christoph

Publication type:

Article

Stereoselective Synthesis of Novel Sphingoid Bases Utilized for Exploring the Secrets of Sphinx.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 15, p. 8171, doi. 10.3390/ijms22158171

By:

Saied, Essa M.;
Arenz, Christoph

Publication type:

Article

Sphingolipid-Transporting Proteins as Cancer Therapeutic Targets.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 14, p. 3554, doi. 10.3390/ijms20143554

By:

Samaha, Doaa;
Hamdo, Housam H.;
Wilde, Max;
Prause, Kevin;
Arenz, Christoph

Publication type:

Article

Heat shock protein–based therapy as a potential candidate for treating the sphingolipidoses.

Published in:

Science Translational Medicine, 2016, v. 8, n. 355, p. 1, doi. 10.1126/scitranslmed.aad9823

By:

Kirkegaard, Thomas;
Gray, James;
Priestman, David A.;
Wallom, Kerri-Lee;
Atkins, Jennifer;
Olsen, Ole Dines;
Klein, Alexander;
Drndarski, Svetlana;
Petersen, Nikolaj H. T.;
Ingemann, Linda;
Smith, David A.;
Morris, Lauren;
Bornæs, Claus;
Jørgensen, Signe Humle;
Williams, Ian;
Hinsby, Anders;
Arenz, Christoph;
Begley, David;
Jäättelä, Marja;
Platt, Frances M.

Publication type:

Article

Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases**.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 2, p. 1, doi. 10.1002/anie.202109967

By:

Healey, Robert D.;
Saied, Essa M.;
Cong, Xiaojing;
Karsai, Gergely;
Gabellier, Ludovic;
Saint‐Paul, Julie;
Del Nero, Elise;
Jeannot, Sylvain;
Drapeau, Marion;
Fontanel, Simon;
Maurel, Damien;
Basu, Shibom;
Leyrat, Cedric;
Golebiowski, Jérôme;
Bossis, Guillaume;
Bechara, Cherine;
Hornemann, Thorsten;
Arenz, Christoph;
Granier, Sebastien

Publication type:

Article

Inside Cover: Resolving Sphingolipid Isomers Using Cryogenic Infrared Spectroscopy (Angew. Chem. Int. Ed. 32/2020).

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 32, p. 13126, doi. 10.1002/anie.202007701

By:

Kirschbaum, Carla;
Saied, Essa M.;
Greis, Kim;
Mucha, Eike;
Gewinner, Sandy;
Schöllkopf, Wieland;
Meijer, Gerard;
Helden, Gert;
Poad, Berwyck L. J.;
Blanksby, Stephen J.;
Arenz, Christoph;
Pagel, Kevin

Publication type:

Article

Resolving Sphingolipid Isomers Using Cryogenic Infrared Spectroscopy.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 32, p. 13638, doi. 10.1002/anie.202002459

By:

Kirschbaum, Carla;
Saied, Essa M.;
Greis, Kim;
Mucha, Eike;
Gewinner, Sandy;
Schöllkopf, Wieland;
Meijer, Gerard;
Helden, Gert;
Poad, Berwyck L. J.;
Blanksby, Stephen J.;
Arenz, Christoph;
Pagel, Kevin

Publication type:

Article

Image‐Based Morphological Profiling Identifies a Lysosomotropic, Iron‐Sequestering Autophagy Inhibitor.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 14, p. 5721, doi. 10.1002/anie.201913712

By:

Laraia, Luca;
Garivet, Guillaume;
Foley, Daniel J.;
Kaiser, Nadine;
Müller, Sebastian;
Zinken, Sarah;
Pinkert, Thomas;
Wilke, Julian;
Corkery, Dale;
Pahl, Axel;
Sievers, Sonja;
Janning, Petra;
Arenz, Christoph;
Wu, Yaowen;
Rodriguez, Raphaël;
Waldmann, Herbert

Publication type:

Article

Lung Endothelial Ca<sup>2+</sup> and Permeability Response to Platelet-Activating Factor Is Mediated by Acid Sphingomyelinase and Transient Receptor Potential Classical 6.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2012, v. 185, n. 2, p. 160, doi. 10.1164/rccm.201104-0717OC

By:

Samapati, Rudi;
Yang Yang;
Jun Yin;
Stoerger, Christof;
Arenz, Christoph;
Dietrich, Alexander;
Gudermann, Thomas;
Adam, Dieter;
Songwei Wu;
Freichel, Marc;
Flockerzi, Veit;
Uhlig, Stefan;
Kuebler, Wolfgang M.

Publication type:

Article

Lebendzell‐Identifizierung von Inhibitoren des Lipid‐Transfer Proteins CERT Mithilfe von Nanoluciferase Bioluminescence Resonance Energy Transfer (NanoBRET).

Published in:

Angewandte Chemie, 2024, v. 136, n. 52, p. 1, doi. 10.1002/ange.202413562

By:

Kirmpaki, Maria‐Anna;
Saied, Essa M.;
Schumacher, Fabian;
Prause, Kevin;
Kleuser, Burkhard;
Arenz, Christoph

Publication type:

Article

Differences and Similarities in TRAIL- and Tumor Necrosis Factor- Mediated Necroptotic Signaling in Cancer Cells

Published in:

Molecular & Cellular Biology, 2016, v. 36, n. 20, p. 2626, doi. 10.1128/MCB.00941-15

By:

Sosna, Justyna;
Philipp, Stephan;
Chico, Johaiber Fuchslocher;
Saggau, Carina;
Fritsch, Jürgen;
Föll, Alexandra;
Plenge, Johannes;
Schütze, Stefan;
Adam, Dieter;
Arenz, Christoph;
Pinkert, Thomas;
Kalthoff, Holger;
Trauzold, Anna;
Schmitz, Ingo

Publication type:

Article

Liposomal FRET Assay Identifies Potent Drug‐Like Inhibitors of the Ceramide Transport Protein (CERT).

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 70, p. 16616, doi. 10.1002/chem.202003283

By:

Samaha, Doaa;
Hamdo, Housam H.;
Cong, Xiaojing;
Schumacher, Fabian;
Banhart, Sebastian;
Aglar, Öznur;
Möller, Heiko M.;
Heuer, Dagmar;
Kleuser, Burkhard;
Saied, Essa M.;
Arenz, Christoph

Publication type:

Article

A Novel Visible Range FRET Probe for Monitoring Acid Sphingomyelinase Activity in Living Cells.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 26, p. 5780, doi. 10.1002/chem.202000133

By:

Kappe, Christian;
Mohamed, Zainelabdeen H.;
Naser, Eyad;
Carpinteiro, Alexander;
Arenz, Christoph

Publication type:

Article

Cover Picture: Development of a Novel FRET Probe for the Real-Time Determination of Ceramidase Activity (ChemBioChem 9/2013).

Published in:

ChemBioChem, 2013, v. 14, n. 9, p. 1017, doi. 10.1002/cbic.201390029

By:

Bhabak, Krishna P.;
Hauser, Anett;
Redmer, Susanne;
Banhart, Sebastian;
Heuer, Dagmar;
Arenz, Christoph

Publication type:

Article

Development of a Novel FRET Probe for the Real-Time Determination of Ceramidase Activity.

Published in:

ChemBioChem, 2013, v. 14, n. 9, p. 1049, doi. 10.1002/cbic.201300207

By:

Bhabak, Krishna P.;
Hauser, Anett;
Redmer, Susanne;
Banhart, Sebastian;
Heuer, Dagmar;
Arenz, Christoph

Publication type:

Article

A Rapid Assay for miRNA Maturation by Using Unmodified pre-miRNA.

Published in:

ChemBioChem, 2011, v. 12, n. 15, p. 2302, doi. 10.1002/cbic.201100445

By:

Neubacher, Saskia;
Dojahn, Claudine M.;
Arenz, Christoph

Publication type:

Article

Potent Inhibition of Acid Sphingomyelinase by Phosphoinositide Analogues.

Published in:

ChemBioChem, 2009, v. 10, n. 14, p. 2367, doi. 10.1002/cbic.200900281

By:

Roth, Anke Gundula;
Redmer, Susanne;
Arenz, Christoph

Publication type:

Article

Rolling-Circle Amplification: Unshared Advantages in miRNA Detection.

Published in:

ChemBioChem, 2009, v. 10, n. 8, p. 1289, doi. 10.1002/cbic.200900116

By:

Neubacher, Saskia;
Arenz, Christoph

Publication type:

Article

Manumycin A and Its Analogues Are Irreversible Inhibitors of Neutral Sphingomyelinase.

Published in:

ChemBioChem, 2001, v. 2, n. 2, p. 141, doi. 10.1002/1439-7633(20010202)2:2<141::AID-CBIC141>3.0.CO;2-P

By:

Arenz, Christoph;
Thutewohl, Michael;
Block, Oliver;
Waldmann, Herbert;
Altenbach, Hans-Josef;
Giannis, Athanassios

Publication type:

Article

A Homogenous Assay for Micro RNA Maturation.

Published in:

Angewandte Chemie International Edition, 2006, v. 45, n. 33, p. 5550, doi. 10.1002/anie.200601332

By:

Davies, Brian P.;
Arenz, Christoph

Publication type:

Article

MicroRNAs—Future Drug Targets?The author thanks the Fonds der Chemischen Industrie and the Innovationsfond der Humboldt-Universität zu Berlin for financial support.

Published in:

Angewandte Chemie International Edition, 2006, v. 45, n. 31, p. 5048, doi. 10.1002/anie.200601537

By:

Christoph Arenz

Publication type:

Article

Synthesis of the First Selective Irreversible Inhibitor of Neutral Sphingomyelinase.

Published in:

Angewandte Chemie International Edition, 2000, v. 39, n. 8, p. 1440, doi. 10.1002/(SICI)1521-3773(20000417)39:8<1440::AID-ANIE1440>3.0.CO;2-R

By:

Arenz, Christoph;
Giannis, Athanassios

Publication type:

Article

Regioselective Diazo-Transfer Reaction at the C3-Position of the 2-Desoxystreptamine Ring of Neamine Antibiotics.

Published in:

Chemistry - A European Journal, 2013, v. 19, n. 28, p. 9151, doi. 10.1002/chem.201300912

By:

Bastian, Andreas A.;
Warszawik, Eliza M.;
Panduru, Praveen;
Arenz, Christoph;
Herrmann, Andreas

Publication type:

Article

Eine durch Lipid-Wasser-Trennung verstärkte FRET-Sonde zur Detektion der Sauren Sphingomyelinase in lebenden Zellen.

Published in:

Angewandte Chemie, 2017, v. 129, n. 10, p. 2834, doi. 10.1002/ange.201611706

By:

Pinkert, Thomas;
Furkert, David;
Korte, Thomas;
Herrmann, Andreas;
Arenz, Christoph

Publication type:

Article

The cellular ceramide transport protein CERT promotes Chlamydia psittaci infection and controls bacterial sphingolipid uptake.

Published in:

Cellular Microbiology, 2017, v. 19, n. 10, p. n/a, doi. 10.1111/cmi.12752

By:

Koch‐Edelmann, Sophia;
Banhart, Sebastian;
Saied, Essa M.;
Rose, Laura;
Aeberhard, Lukas;
Laue, Michael;
Doellinger, Joerg;
Arenz, Christoph;
Heuer, Dagmar

Publication type:

Article

Facile Synthesis of the CERT Inhibitor HPA-12 and Some Novel Derivatives.

Published in:

Chemistry - An Asian Journal, 2014, v. 9, n. 8, p. 2092, doi. 10.1002/asia.201402241

By:

Saied, Essa M.;
Diederich, Stephanie;
Arenz, Christoph

Publication type:

Article

TRAIL-induced programmed necrosis as a novel approach to eliminate tumor cells.

Published in:

BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-74

By:

Voigt, Susann;
Philipp, Stephan;
Davarnia, Parvin;
Winoto-Morbach, Supandi;
Röder, Christian;
Arenz, Christoph;
Trauzold, Anna;
Kabelitz, Dieter;
Schütze, Stefan;
Kalthoff, Holger;
Adam, Dieter

Publication type:

Article

TRAIL-induced programmed necrosis as a novel approach to eliminate tumor cells.

Published in:

2014

By:

Voigt, Susann;
Philipp, Stephan;
Davarnia, Parvin;
Winoto-Morbach, Supandi;
Röder, Christian;
Arenz, Christoph;
Trauzold, Anna;
Kabelitz, Dieter;
Schütze, Stefan;
Kalthoff, Holger;
Adam, Dieter

Publication type:

journal article

The Activity of the Neutral Sphingomyelinase Is Important in T Cell Recruitment and Directional Migration.

Published in:

Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01007

By:

Collenburg, Lena;
Beyersdorf, Niklas;
Wiese, Teresa;
Arenz, Christoph;
Saied, Essa M.;
Becker-Flegler, Katrin Anne;
Schneider-Schaulies, Sibylle;
Avota, Elita

Publication type:

Article

Synthesis of the First Selective Irreversible Inhibitor of Neutral Sphingomyelinase.

Published in:

European Journal of Organic Chemistry, 2001, v. 2001, n. 1, p. 137, doi. 10.1002/1099-0690(200101)2001:1<137::AID-EJOC137>3.0.CO;2-#

By:

Arenz, Christoph;
Giannis, Athanassios

Publication type:

Article

Expression levels of the microRNA maturing microprocessor complex component DGCR8 and the RNA-induced silencing complex (RISC) components argonaute-1, argonaute-2, PACT, TARBP1, and TARBP2 in epithelial skin cancer.

Published in:

Molecular Carcinogenesis, 2012, v. 51, n. 11, p. 916, doi. 10.1002/mc.20861

By:

Sand, Michael;
Skrygan, Marina;
Georgas, Dimitrios;
Arenz, Christoph;
Gambichler, Thilo;
Sand, Daniel;
Altmeyer, Peter;
Bechara, Falk G.

Publication type:

Article

Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology.

Published in:

Nature, 2010, v. 463, n. 7280, p. 549, doi. 10.1038/nature08710

By:

Kirkegaard, Thomas;
Roth, Anke G.;
Petersen, Nikolaj H. T.;
Mahalka, Ajay K.;
Olsen, Ole Dines;
Moilanen, Irina;
Zylicz, Alicja;
Knudsen, Jens;
Sandhoff, Konrad;
Arenz, Christoph;
Kinnunen, Paavo K. J.;
Nylandsted, Jesper;
Jäättelä, Marja

Publication type:

Article

Amplification of a FRET Probe by Lipid-Water Partition for the Detection of Acid Sphingomyelinase in Live Cells.

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 10, p. 2790, doi. 10.1002/anie.201611706

By:

Pinkert, Thomas;
Furkert, David;
Korte, Thomas;
Herrmann, Andreas;
Arenz, Christoph

Publication type:

Article