Works by Archer, Stephen L.

Results: 72

Tet Methylcytosine Dioxygenase 2 (TET2) Mutation Drives a Global Hypermethylation Signature in Patients With Pulmonary Arterial Hypertension (PAH): Correlation With Altered Gene Expression Relevant to a Common T Cell Phenotype.

Published in:

Comprehensive Physiology, 2025, v. 15, n. 2, p. 1, doi. 10.1002/cph4.70011

By:

Hindmarch, Charles C. T.;
Potus, François;
Al‐Qazazi, Ruaa;
Ott, Benjamin P.;
Nichols, William C.;
Rauh, Michael J.;
Archer, Stephen L.

Publication type:

Article

Hypertensive urgency due to cholesterol embolization of kidneys.

Published in:

American Journal of Hypertension, 1995, v. 8, n. 9, p. 954, doi. 10.1016/0895-7061(95)00223-C

By:

Simon, Geza;
Archer, Stephen L.

Publication type:

Article

Home Virtual Visits for Outpatient Follow-Up Stroke Care: Cross-Sectional Study.

Published in:

2019

By:

Appireddy, Ramana;
Khan, Sana;
Leaver, Chad;
Martin, Cally;
Jin, Albert;
Durafourt, Bryce A;
Archer, Stephen L

Publication type:

journal article

Hypoxic Pulmonary Vasoconstriction: An Important Component of the Homeostatic Oxygen Sensing System.

Published in:

Physiological Research, 2024, v. 73, p. S493, doi. 10.33549/physiolres.935431

By:

ARCHER, Stephen L.;
DUNHAM SNARY, Kimberly J.;
BENTLEY, Rachel E. T.;
ALIZADEH, Elahe;
WEIR, E. Kenneth

Publication type:

Article

Myocardial damage in patients with sarcoidosis and preserved left ventricular systolic function: an observational study.

Published in:

European Journal of Heart Failure, 2011, v. 13, n. 11, p. 1231, doi. 10.1093/eurjhf/hfr099

By:

Patel, Amit R.;
Klein, Michael R.;
Chandra, Sonal;
Spencer, Kirk T.;
DeCara, Jeanne M.;
Lang, Roberto M.;
Burke, Martin C.;
Garrity, Edward R.;
Hogarth, D. Kyle;
Archer, Stephen L.;
Sweiss, Nadera J.;
Beshai, John F.

Publication type:

Article

The making of a physician-scientist—the process has a pattern: lessons from the lives of Nobel laureates in medicine and physiology.

Published in:

European Heart Journal, 2007, v. 28, n. 4, p. 510, doi. 10.1093/eurheartj/ehl452

By:

Archer, Stephen L.

Publication type:

Article

Pulmonary hypertension begets pulmonary hypertension: mutually reinforcing roles for haemodynamics, inflammation, and cancer-like phenotypes.

Published in:

Cardiovascular Research, 2016, v. 111, n. 1, p. 1, doi. 10.1093/cvr/cvw110

By:

Danchen Wu;
Archer, Stephen L.

Publication type:

Article

Nebulized nitric oxide/nucleophile adduct reduces chronic pulmonary hypertension.

Published in:

Cardiovascular Research, 1996, v. 31, n. 1, p. 55, doi. 10.1016/0008-6363(95)00172-7

By:

Hampl, Václav;
Tristani-Firouzi, Martin;
Hutsell, Thomas C.;
Archer, Stephen L.

Publication type:

Article

PINK1‐induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension.

Published in:

FASEB Journal, 2021, v. 35, n. 8, p. 1, doi. 10.1096/fj.202100361R

By:

Dasgupta, Asish;
Chen, Kuang‐Hueih;
Lima, Patricia D. A.;
Mewburn, Jeffrey;
Wu, Danchen;
Al‐Qazazi, Ruaa;
Jones, Oliver;
Tian, Lian;
Potus, Francois;
Bonnet, Sebastien;
Archer, Stephen L.

Publication type:

Article

An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications.

Published in:

FASEB Journal, 2020, v. 34, n. 4, p. 5106, doi. 10.1096/fj.201903117R

By:

Dasgupta, Asish;
Chen, Kuang‐Hueih;
Wu, Danchen;
Hoskin, Victoria;
Mewburn, Jeffrey;
Lima, Patricia D. A.;
Parlow, Leah R. G.;
Hindmarch, Charles C. T.;
Martin, Ashley;
Sykes, Edward A.;
Tayade, Chandrakant;
Lightbody, Elizabeth D.;
Madarnas, Yolanda;
SenGupta, Sandip K.;
Elliott, Bruce E.;
Nicol, Christopher J. B.;
Archer, Stephen L.

Publication type:

Article

Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury.

Published in:

FASEB Journal, 2020, v. 34, n. 1, p. 1447, doi. 10.1096/fj.201901467R

By:

Wu, Danchen;
Dasgupta, Asish;
Chen, Kuang‐Hueih;
Neuber‐Hess, Monica;
Patel, Jignesh;
Hurst, Timothy E.;
Mewburn, Jeffrey D.;
Lima, Patricia D. A.;
Alizadeh, Elahe;
Martin, Ashley;
Wells, Michael;
Snieckus, Victor;
Archer, Stephen L.

Publication type:

Article

Dynamin-related protein 1 (Drpl)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drpl inhibition to reduce mitochondrial fission.

Published in:

FASEB Journal, 2014, v. 28, n. 1, p. 316, doi. 10.1096/fj.12-226225

By:

Sharp, Willard W.;
Yong Hu Fang;
Mei Han;
Hannah J. Zhang;
Zhigang Hong;
Banathy, Alexandra;
Morrow, Erik;
Ryan, John J.;
Archer, Stephen L.

Publication type:

Article

Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer.

Published in:

FASEB Journal, 2012, v. 26, n. 5, p. 2175, doi. 10.1096/fj.11-196543

By:

Rehman, Jalees;
Zhang, Hannah J.;
Toth, Peter T.;
Yanmin Zhang;
Marsboom, Glenn;
Zhigang Hong;
Salgia, Ravi;
Husain, Aliya N.;
Wietholt, Christian;
Archer, Stephen L.

Publication type:

Article

The neurovascular mechanism of clitoral erection: nitric oxide and cGMP-stimulated activation of BKCa channels.

Published in:

FASEB Journal, 2004, v. 18, n. 12, p. 1382, doi. 10.1096/fj.04-1978com

By:

Gragasin, Ferrante S.;
Michelakis, Evangelos D.;
Hogan, Angie;
Moudgil, Rohit;
Hashimoto, Kyoko;
Xichen Wu;
Bonnet, Sandra;
Haromy, Al;
Archer, Stephen L.

Publication type:

Article

O2 sensing in the human ductus arteriosus: redox-sensitive K + channels are regulated by mitochondria-derived hydrogen peroxide.

Published in:

Biological Chemistry, 2004, v. 385, n. 3/4, p. 205, doi. 10.1515/BC.2004.014

By:

Archer, Stephen L.;
Xi-Chen Wu;
Thébaud, Bernard;
Moudgil, Rohit;
Hashimoto, Kyoko;
Michelakis, Evangelos D.

Publication type:

Article

Gone fission: an asymptomatic STAT2 mutation elongates mitochondria and causes human disease following viral infection.

Published in:

2015

By:

Dasgupta, Asish;
Kuang-Hueih Chen;
Lian Tian;
Archer, Stephen L.;
Chen, Kuang-Hueih;
Tian, Lian

Publication type:

journal article

Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra‐coronary aortic banding.

Published in:

Acta Physiologica, 2022, v. 234, n. 2, p. 1, doi. 10.1111/apha.13764

By:

Xiong, Ping Yu;
Motamed, Mehras;
Chen, Kuang‐Hueih;
Dasgupta, Asish;
Potus, François;
Tian, Lian;
Martin, Ashley;
Mewburn, Jeffrey;
Jones, Oliver;
Thébaud, Arthur;
Archer, Stephen L.

Publication type:

Article

Supra‐coronary aortic banding improves right ventricular function in experimental pulmonary arterial hypertension in rats by increasing systolic right coronary artery perfusion.

Published in:

Acta Physiologica, 2020, v. 229, n. 4, p. 1, doi. 10.1111/apha.13483

By:

Tian, Lian;
Xiong, Ping Yu;
Alizadeh, Elahe;
Lima, Patricia D. A.;
Potus, François;
Mewburn, Jeffrey;
Martin, Ashley;
Chen, Kuang‐Hueih;
Archer, Stephen L.

Publication type:

Article

Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement.

Published in:

2018

By:

Lahm, Tim;
Douglas, Ivor S;
Archer, Stephen L;
Bogaard, Harm J;
Chesler, Naomi C;
Haddad, Francois;
Hemnes, Anna R;
Kawut, Steven M;
Kline, Jeffrey A;
Kolb, Todd M;
Mathai, Stephen C;
Mercier, Olaf;
Michelakis, Evangelos D;
Naeije, Robert;
Tuder, Rubin M;
Ventetuolo, Corey E;
Vieillard-Baron, Antoine;
Voelkel, Norbert F;
Vonk-Noordegraaf, Anton;
Hassoun, Paul M

Publication type:

journal article

Disproportionate Right Ventricular Dysfunction and Poor Survival in Group 3 Pulmonary Hypertension.

Published in:

2018

By:

Prins, Kurt W.;
Rose, Lauren;
Archer, Stephen L.;
Pritzker, Marc;
Weir, E. Kenneth;
Kazmirczak, Felipe;
Misialek, Jeffrey R.;
Thenappan, Thenappan

Publication type:

research

MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype.

Published in:

2017

By:

Zhigang Hong;
Kuang-Hueih Chen;
DasGupta, Asish;
Potus, Francois;
Dunham-Snary, Kimberly;
Bonnet, Sebastien;
Tian, Lian;
Fu, Jennifer;
Breuils-Bonnet, Sandra;
Provencher, Steeve;
Danchen Wu;
Mewburn, Jeffrey;
Ormiston, Mark L.;
Archer, Stephen L.;
Hong, Zhigang;
Chen, Kuang-Hueih;
Wu, Danchen

Publication type:

journal article

Executive Summary of the American Heart Association and American Thoracic Society Joint Guidelines for Pediatric Pulmonary Hypertension.

Published in:

2016

By:

Abman, Steven H.;
Ivy, D. Dunbar;
Archer, Stephen L.;
Wilson, Kevin;
AHA/ATS Joint Guidelines for Pediatric Pulmonary Hypertension Committee

Publication type:

journal article

Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension.

Published in:

2016

By:

Hemnes, Anna R.;
Min Zhao;
West, James;
Newman, John H.;
Rich, Stuart;
Archer, Stephen L.;
Robbins, Ivan M.;
Blackwell, Timothy S.;
Cogan, Joy;
Loyd, James E.;
Zhongming Zhao;
Gaskill, Christa;
Jetter, Christopher;
Kropski, Jonathan A.;
Majka, Susan M.;
Austin, Eric D.;
Zhao, Min;
Zhao, Zhongming

Publication type:

journal article

PGC1 ɑ-mediated Mitofusin-2 Deficiency in Female Rats and Humans with Pulmonary Arterial Hypertension.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2013, v. 187, n. 8, p. 865, doi. 10.1164/rccm.201209-1687oc

By:

Ryan, John J.;
Marsboom, Glenn;
Yong-Hu Fang;
Toth, Peter T.;
Morrow, Erik;
Luo, Nancy;
Piao, Lin;
Hong, Zhigang;
Ericson, Kyle;
Zhang, Hannah J.;
Han, Mei;
Haney, Chad R.;
Chin-Tu Chen;
Sharp, Willard W.;
Archer, Stephen L.

Publication type:

Article

Evolving epidemiology of pulmonary arterial hypertension.

Published in:

2012

By:

Thenappan T;
Ryan JJ;
Archer SL;
Thenappan, Thenappan;
Ryan, John J;
Archer, Stephen L

Publication type:

Editorial

Evolving Epidemiology of Pulmonary Arterial Hypertenslon.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2012, v. 186, n. 8, p. 707, doi. 10.1164/rccm.201207-1266ED

By:

THENAPPAN, THENAPPAN;
RYAN, JOHN J.;
ARCHER, STEPHEN L.

Publication type:

Article

Lung 18F-Fluorodeoxyglucose Positron Emission Tomography for Diagnosis and Monitoring of Pulmonary Arterial Hypertension.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2012, v. 185, n. 6, p. 670, doi. 10.1164/rccm.201108-1562OC

By:

Marsboom, Glenn;
Wietholt, Christian;
Haney, Chad R.;
Toth, Peter T.;
Ryan, John J.;
Morrow, Erik;
Thenappan, Thenappan;
Bache-Wiig, Peter;
Lin Piao;
Paul, Jonathan;
Chin-Tu Chen;
Archer, Stephen L.

Publication type:

Article

Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease.

Published in:

2008

By:

Rey-Parra GJ;
Archer SL;
Bland RD;
Albertine KH;
Carlton DP;
Cho SC;
Kirby B;
Haromy A;
Eaton F;
Wu X;
Thébaud B;
Rey-Parra, Gloria Juliana;
Archer, Stephen L;
Bland, Richard D;
Albertine, Kurt H;
Carlton, David P;
Cho, Soo-Chul;
Kirby, Beth;
Haromy, Al;
Eaton, Farah

Publication type:

journal article

Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.

Published in:

2005

By:

McMurtry, M. Sean;
Archer, Stephen L.;
Altieri, Dario C.;
Bonnet, Sebastien;
Haromy, Alois;
Harry, Gwyneth;
Bonnet, Sandra;
Puttagunta, Lakshmi;
Michelakis, Evangelos D.

Publication type:

journal article

SIRT3 Deacetylates and Activates OPA1 To Regulate Mitochondrial Dynamics during Stress.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 5, p. 807, doi. 10.1128/MCB.01483-13

By:

Samant, Sadhana A.;
Zhang, Hannah J.;
Hong, Zhigang;
Pillai, Vinodkumar B.;
Sundaresan, Nagalingam R.;
Wolfgeher, Donald;
Archer, Stephen L.;
Chan, David C.;
Gupta, Mahesh P.

Publication type:

Article

Alteration of Decreased Plasma NO Metabolites and Platelet NO Synthase Activity by Paroxetine in Depressed Patients.

Published in:

Neuropsychopharmacology, 2006, v. 31, n. 6, p. 1286, doi. 10.1038/sj.npp.1300961

By:

Chrapko, Wendy;
Jurasz, Paul;
Radomski, Marek W.;
Archer, Stephen L.;
Newman, Stephen C.;
Baker, Glen;
Lara, Nathalie;
Le Mellédo, Jean-Michel

Publication type:

Article

Pulmonary and Systemic Nitric Oxide Measurements During CCK-5-Induced Panic Attacks.

Published in:

Neuropsychopharmacology, 2003, v. 28, n. 10, p. 1840, doi. 10.1038/sj.npp.1300241

By:

Lara, Nathalie;
Chrapko, Wendy E.;
Archer, Stephen L.;
Bellavance, François;
Mayers, Irvin;
Le Mellédo, Jean-Michel

Publication type:

Article

Electron Leak From the Mitochondrial Electron Transport Chain Complex I at Site I Q Is Crucial for Oxygen Sensing in Rabbit and Human Ductus Arteriosus.

Published in:

Journal of the American Heart Association, 2023, v. 12, n. 13, p. 1, doi. 10.1161/JAHA.122.029131

By:

Read, Austin D.;
Bentley, Rachel E. T.;
Martin, Ashley Y.;
Mewburn, Jeffrey D.;
Alizadeh, Elahe;
Danchen Wu;
Lima, Patricia D. A.;
Dunham-Snary, Kimberly J.;
Thébaud, Bernard;
Sharp, Willard;
Archer, Stephen L.

Publication type:

Article

Effect of Chronic Digoxin Use on Mortality and Heart Failure Hospitalization in Pulmonary Arterial Hypertension.

Published in:

Journal of the American Heart Association, 2023, v. 12, n. 6, p. 1, doi. 10.1161/JAHA.122.027559

By:

Chang, Kevin Y.;
Giorgio, Katherine;
Schmitz, Katlin;
Walker, Rob F.;
Prins, Kurt W.;
Pritzker, Marc R.;
Archer, Stephen L.;
Lutsey, Pamela L.;
Thenappan, Thenappan

Publication type:

Article

Persistence of complex vascular lesions despite prolonged prostacyclin therapy of pulmonary arterial hypertension.

Published in:

Histopathology, 2012, v. 61, n. 4, p. 597, doi. 10.1111/j.1365-2559.2012.04246.x

By:

Pogoriler, Jennifer E.;
Rich, Stuart;
Archer, Stephen L.;
Husain, Aliya N.

Publication type:

Article

Increased Drp1-Mediated Mitochondrial Fission Promotes Proliferation and Collagen Production by Right Ventricular Fibroblasts in Experimental Pulmonary Arterial Hypertension.

Published in:

Frontiers in Physiology, 2018, p. N.PAG, doi. 10.3389/fphys.2018.00828

By:

Tian, Lian;
Potus, Francois;
Wu, Danchen;
Dasgupta, Asish;
Chen, Kuang-Hueih;
Mewburn, Jeffrey;
Lima, Patricia;
Archer, Stephen L.

Publication type:

Article

Pulmoner hipertansiyon patoloji ve patobiyolojisi ile ilişkili konular.

Published in:

Archives of the Turkish Society of Cardiology / Türk Kardiyoloji Derneği Arşivi, 2014, v. 42, n. Supp 1, p. 23

By:

Tuder, Rubin M.;
Archer, Stephen L.;
Dorfmüller, Peter;
Erzurum, Serpil C.;
Guignabert, Christophe;
Michelakis, Evangelos;
Rabinovitch, Marlene;
Schermuly, Ralph;
Stenmark, Kurt R.;
Morrell, Nicholas W.

Publication type:

Article

Diversity of response in vascular smooth muscle cells to changes in oxygen tension.

Published in:

Kidney International, 1997, v. 51, n. 2, p. 462, doi. 10.1038/ki.1997.62

By:

Weir, E. Kenneth;
Reeve, Helen L.;
Cornfield, David N.;
Tristani-Firouzi, Martin;
Peterson, Douglas A.;
Archer, Stephen L.

Publication type:

Article

Inducible nitric oxide synthase mRNA and activity in glomerular mesangial cells.

Published in:

Kidney International, 1994, v. 46, n. 3, p. 683, doi. 10.1038/ki.1994.321

By:

Shultz, Pamela J.;
Archer, Stephen L.;
Rosenberg, Mark E.

Publication type:

Article

Carvedilol for Treatment of Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.

Published in:

2021

By:

Thenappan Thenappan;
Weir, E. Kenneth;
Prins, Kurt W.;
Pritzker, Marc R.;
Archer, Stephen L.;
Thenappan, Thenappan

Publication type:

Letter

Hypochloremia Is a Noninvasive Predictor of Mortality in Pulmonary Arterial Hypertension.

Published in:

2020

By:

Prins, Kurt W.;
Kalra, Rajat;
Rose, Lauren;
Assad, Tufik R.;
Archer, Stephen L.;
Bajaj, Navkaranbir S.;
Weir, E. Kenneth;
Prisco, Sasha Z.;
Pritzker, Marc;
Lutsey, Pamela L.;
Brittain, Evan L.;
Thenappan, Thenappan

Publication type:

journal article

Clinical Determinants and Prognostic Implications of Right Ventricular Dysfunction in Pulmonary Hypertension Caused by Chronic Lung Disease.

Published in:

2019

By:

Prins, Kurt W.;
Rose, Lauren;
Archer, Stephen L.;
Pritzker, Marc;
Weir, E. Kenneth;
Olson, Matthew D.;
Thenappan, Thenappan

Publication type:

journal article

Repurposing Medications for Treatment of Pulmonary Arterial Hypertension: What's Old Is New Again.

Published in:

2019

By:

Prins, Kurt W.;
Thenappan, Thenappan;
Weir, E. Kenneth;
Kalra, Rajat;
Pritzker, Marc;
Archer, Stephen L.

Publication type:

journal article

Colchicine Depolymerizes Microtubules, Increases Junctophilin-2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension.

Published in:

2017

By:

Prins, Kurt W.;
Tian, Lian;
Wu, Danchen;
Thenappan, Thenappan;
Metzger, Joseph M.;
Archer, Stephen L.

Publication type:

journal article

Using health administrative data to identify patients with pulmonary hypertension: A single center, proof of concept validation study in Ontario, Canada.

Published in:

Pulmonary Circulation, 2022, v. 12, n. 1, p. 1, doi. 10.1002/pul2.12040

By:

Wijeratne, Don Thiwanka;
Housin, Ahmad;
Lajkosz, Katherine;
Lougheed, M. Diane;
Xiong, Ping Yu;
Barber, David;
Doliszny, Katharine M.;
Archer, Stephen L.

Publication type:

Article

Pathophysiology, incidence, management, and consequences of cardiac arrhythmia in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.

Published in:

Pulmonary Circulation, 2019, v. 9, n. 1, p. 1, doi. 10.1177/2045894019834890

By:

Cirulis, Meghan M.;
Ryan, John J.;
Archer, Stephen L.

Publication type:

Article

Resistance over compliance describes right ventricular afterload better than resistance-compliance time: a friendly amendment.

Published in:

Pulmonary Circulation, 2017, v. 7, n. 1, p. 275, doi. 10.1177/2045893216681025

By:

Thenappan, Thenappan;
Archer, Stephen L.;
Weir, E. Kenneth

Publication type:

Article

Pulmonary pulse wave transit time is associated with right ventricular-pulmonary artery coupling in pulmonary arterial hypertension.

Published in:

Pulmonary Circulation, 2016, v. 6, n. 4, p. 576, doi. 10.1086/688879

By:

Prins, Kurt W.;
Weir, E. Kenneth;
Archer, Stephen L.;
Markowitz, Jeremy;
Rose, Lauren;
Pritzker, Marc;
Madlon-Kay, Richard;
Thenappan, Thenappan

Publication type:

Article

The first Keystone Symposia Conference on pulmonary vascular disease and right ventricular dysfunction: Current concepts and future therapies.

Published in:

2013

By:

von Gise, Alexander;
Archer, Stephen L.;
MacLean, Margaret R.;
Hansmann, Georg

Publication type:

Proceeding

Anticipated classes of new medications and molecular targets for pulmonary arterial hypertension.

Published in:

Pulmonary Circulation, 2013, v. 3, n. 1, p. 226, doi. 10.4103/2045-8932.109940

By:

Morrell, Nicholas W.;
Archer, Stephen L.;
DeFelice, Albert;
Evans, Steven;
Fiszman, Monica;
Martin, Thomas;
Saulnier, Muriel;
Rabinovitch, Marlene;
Schermuly, Ralph;
Stewart, Duncan;
Truebel, Hubert;
Walker, Gennyne;
Stenmark, Kurt R.

Publication type:

Article