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Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine-gingipain inhibitor COR388.
Published in:
Pharmacology Research & Perspectives, 2020, v. 8, n. 1, p. 1, doi. 10.1002/prp2.562
By:
- Arastu-Kapur, Shirin;
- Mai Nguyen;
- Raha, Debasish;
- Ermini, Florian;
- Haditsch, Ursula;
- Araujo, Joseph;
- De Lannoy, Ines A. M.;
- Ryder, Mark I.;
- Dominy, Stephen S.;
- Lynch, Casey;
- Holsinger, Leslie J.
Publication type:
Article
Immunoproteasome functions explained by divergence in cleavage specificity and regulation.
Published in:
eLife, 2017, p. 1, doi. 10.7554/eLife.27364.001
By:
- Winter, Michael B.;
- La Greca, Florencia;
- Arastu-Kapur, Shirin;
- Caiazza, Francesco;
- Cimermancic, Peter;
- Buchholz, Tonia J.;
- Anderl, Janet L.;
- Ravalin, Matthew;
- Bohn, Markus F.;
- Sali, Andrej;
- O'Donoghue, Anthony J.;
- Craik, Charles S.
Publication type:
Article
Clinical activity of carfilzomib correlates with inhibition of multiple proteasome subunits: application of a novel pharmacodynamic assay.
Published in:
British Journal of Haematology, 2016, v. 173, n. 6, p. 884, doi. 10.1111/bjh.14014
By:
- Lee, Susan J.;
- Levitsky, Konstantin;
- Parlati, Francesco;
- Bennett, Mark K.;
- Arastu‐Kapur, Shirin;
- Kellerman, Lois;
- Woo, Tina F.;
- Wong, Alvin F.;
- Papadopoulos, Kyriakos P.;
- Niesvizky, Ruben;
- Badros, Ashraf Z.;
- Vij, Ravi;
- Jagannath, Sundar;
- Siegel, David;
- Wang, Michael;
- Ahmann, Gregory J.;
- Kirk, Christopher J.
Publication type:
Article
Ricolinostat ( ACY-1215) induced inhibition of aggresome formation accelerates carfilzomib-induced multiple myeloma cell death.
Published in:
British Journal of Haematology, 2015, v. 169, n. 3, p. 423, doi. 10.1111/bjh.13315
By:
- Mishima, Yuko;
- Santo, Loredana;
- Eda, Homare;
- Cirstea, Diana;
- Nemani, Neeharika;
- Yee, Andrew J.;
- O'Donnell, Elizabeth;
- Selig, Martin Karl;
- Quayle, Steven N.;
- Arastu‐Kapur, Shirin;
- Kirk, Christopher;
- Boise, Lawrence H.;
- Jones, Simon S.;
- Raje, Noopur
Publication type:
Article
A first-in-human dose-escalation study of the oral proteasome inhibitor oprozomib in patients with advanced solid tumors.
Published in:
Investigational New Drugs, 2016, v. 34, n. 2, p. 216, doi. 10.1007/s10637-016-0327-x
By:
- Infante, Jeffrey;
- Mendelson, David;
- Burris, Howard;
- Bendell, Johanna;
- Tolcher, Anthony;
- Gordon, Michael;
- Gillenwater, Heidi;
- Arastu-Kapur, Shirin;
- Wong, Hansen;
- Papadopoulos, Kyriakos
Publication type:
Article
Molecular Mechanisms of Bortezomib Resistant Adenocarcinoma Cells.
Published in:
PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0027996
By:
- Suzuki, Erika;
- Demo, Susan;
- Deu, Edgar;
- Keats, Jonathan;
- Arastu-Kapur, Shirin;
- Leif Bergsagel, P.;
- Bennett, Mark K.;
- Kirk, Christopher J.
Publication type:
Article
Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies differences in amino acid preferences between peptide‐based substrates and covalent inhibitors.
Published in:
FEBS Journal, 2019, v. 286, n. 20, p. 3998, doi. 10.1111/febs.14953
By:
- Vries, Laura E.;
- Sanchez, Mateo I.;
- Groborz, Katarzyna;
- Kuppens, Laurie;
- Poreba, Marcin;
- Lehmann, Christine;
- Nevins, Neysa;
- Withers‐Martinez, Chrislaine;
- Hirst, David J.;
- Yuan, Fang;
- Arastu‐Kapur, Shirin;
- Horn, Martin;
- Mares, Michael;
- Bogyo, Matthew;
- Drag, Marcin;
- Deu, Edgar
Publication type:
Article
Falstatin, a Cysteine Protease Inhibitor of Plasmodium falciparum, Facilitates Erythrocyte Invasion.
Published in:
PLoS Pathogens, 2006, v. 2, n. 11, p. 1031, doi. 10.1371/journal.ppat.0020117
By:
- Pandey, Kailash C.;
- Singh, Naresh;
- Arastu-Kapur, Shirin;
- Bogyo, Matthew;
- Rosenthal, Philip J.
Publication type:
Article
Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum.
Published in:
Nature Chemical Biology, 2008, v. 4, n. 3, p. 203, doi. 10.1038/nchembio.70
By:
- Arastu-Kapur, Shirin;
- Ponder, Elizabeth L.;
- Fonović, Urša Pečar;
- Yeoh, Sharon;
- Yuan, Fang;
- Fonović, Marko;
- Grainger, Munira;
- Phillips, Carolyn I.;
- Powers, James C.;
- Bogyo, Matthew
Publication type:
Article
Novel Aza Peptide Inhibitors and Active-Site Probes of Papain-Family Cysteine Proteases.
Published in:
ChemBioChem, 2006, v. 7, n. 6, p. 943, doi. 10.1002/cbic.200600001
By:
- Steven H. L. Verhelst;
- Martin D. Witte;
- Shirin Arastu-Kapur;
- Marko Fonovic;
- Matthew Bogyo
Publication type:
Article

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