Works by Arand, Michael

Results: 27

Recombinant expression of human microsomal epoxide hydrolase protects V79 Chinese hamster cells from styrene oxide- but not from ethylene oxide-induced DNA strand breaks.

Published in:

Environmental & Molecular Mutagenesis, 1997, v. 30, n. 4, p. 429, doi. 10.1002/(SICI)1098-2280(1997)30:4<429::AID-EM8>3.0.CO;2-D

By:

Herrero, María Elena;
Arand, Michael;
Hengstler, Jan Georg;
Oesch, Franz

Publication type:

Article

Drug-induced cholestasis (DIC) predictions based on in vitro inhibition of major bile acid clearance mechanisms.

Published in:

Archives of Toxicology, 2025, v. 99, n. 1, p. 377, doi. 10.1007/s00204-024-03895-z

By:

Kastrinou-Lampou, Vlasia;
Rodríguez-Pérez, Raquel;
Poller, Birk;
Huth, Felix;
Schadt, Heiko S.;
Kullak-Ublick, Gerd A.;
Arand, Michael;
Camenisch, Gian

Publication type:

Article

Identification of reversible OATP1B1 and time-dependent CYP3A4 inhibition as the major risk factors for drug-induced cholestasis (DIC).

Published in:

Archives of Toxicology, 2024, v. 98, n. 10, p. 3409, doi. 10.1007/s00204-024-03794-3

By:

Kastrinou-Lampou, Vlasia;
Rodríguez-Pérez, Raquel;
Poller, Birk;
Huth, Felix;
Gáborik, Zsuzsanna;
Mártonné-Tóth, Beáta;
Temesszentandrási-Ambrus, Csilla;
Schadt, Heiko S.;
Kullak-Ublick, Gerd A.;
Arand, Michael;
Camenisch, Gian

Publication type:

Article

The role of endogenous versus exogenous sources in the exposome of putative genotoxins and consequences for risk assessment.

Published in:

Archives of Toxicology, 2022, v. 96, n. 5, p. 1297, doi. 10.1007/s00204-022-03242-0

By:

Rietjens, Ivonne M. C. M.;
Michael, Arand;
Bolt, Hermann M.;
Siméon, Bourdoux;
Andrea, Hartwig;
Nils, Hinrichsen;
Christine, Kalisch;
Angela, Mally;
Gloria, Pellegrino;
Daniel, Ribera;
Natalie, Thatcher;
Gerhard, Eisenbrand

Publication type:

Article

Opinion: A serious issue with the standardization of the adenovirus-based COVID-19 vaccines?

Published in:

2021

By:

Arand, Michael

Publication type:

Letter

Correction to: Mode of action-based risk assessment of genotoxic carcinogens.

Published in:

2020

By:

Hartwig, Andrea;
Arand, Michael;
Epe, Bernd;
Guth, Sabine;
Jahnke, Gunnar;
Lampen, Alfonso;
Martus, Hans-Jörg;
Monien, Bernhard;
Rietjens, Ivonne M. C. M.;
Schmitz-Spanke, Simone;
Schriever-Schwemmer, Gerlinde;
Steinberg, Pablo;
Eisenbrand, Gerhard

Publication type:

Correction Notice

Mode of action-based risk assessment of genotoxic carcinogens.

Published in:

Archives of Toxicology, 2020, v. 94, n. 6, p. 1787, doi. 10.1007/s00204-020-02733-2

By:

Hartwig, Andrea;
Arand, Michael;
Epe, Bernd;
Guth, Sabine;
Jahnke, Gunnar;
Lampen, Alfonso;
Martus, Hans-Jörg;
Monien, Bernhard;
Rietjens, Ivonne M. C. M.;
Schmitz-Spanke, Simone;
Schriever-Schwemmer, Gerlinde;
Steinberg, Pablo;
Eisenbrand, Gerhard

Publication type:

Article

Metabolic Detoxification: Implications for Thresholds.

Published in:

Toxicologic Pathology, 2000, v. 28, n. 3, p. 382, doi. 10.1177/019262330002800305

By:

Oesch, Franz;
Herrero, Maria Elena;
Hengstler, Jan Georg;
Lohmann, Matthias;
Arand, Michael

Publication type:

Article

Immunoselection in vivo: Independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma.

Published in:

International Journal of Cancer, 1997, v. 71, n. 2, p. 142, doi. 10.1002/(SICI)1097-0215(19970410)71:2<142::AID-IJC3>3.0.CO;2-0

By:

Jäger, Elke;
Ringhoffer, Mark;
Altmannsberger, Michael;
Arand, Michael;
Karbach, Julia;
Jäger, Dirk;
Oesch, Franz;
Knuth, Alexander

Publication type:

Article

Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptides in vivo.

Published in:

International Journal of Cancer, 1996, v. 67, n. 1, p. 54, doi. 10.1002/(SICI)1097-0215(19960703)67:1<54::AID-IJC11>3.0.CO;2-C

By:

Jäger, Elke;
Ringhoffer, Mark;
Dienes, Hans Peter;
Arand, Michael;
Karbach, Julia;
Jäger, Dirk;
Ilsemann, Christiane;
Hagedorn, Manfred;
Oesch, Franz;
Knuth, Alexander

Publication type:

Article

Inverse relationship of melanocyte differentiation antigen expression in melanoma tissues and CD8.

Published in:

International Journal of Cancer, 1996, v. 66, n. 4, p. 470, doi. 10.1002/(SICI)1097-0215(19960516)66:4<470::AID-IJC10>3.0.CO;2-C

By:

Jäger, Elke;
Ringhoffer, Mark;
Karbach, Julia;
Arand, Michael;
Oesch, Franz;
Knuth, Alexander

Publication type:

Article

Generation of cytotoxic T-cell responses with synthetic melanoma-associated peptides in vivo: Implications for tumor vaccines with melanoma-associated antigens.

Published in:

International Journal of Cancer, 1996, v. 66, n. 2, p. 162, doi. 10.1002/(SICI)1097-0215(19960410)66:2<162::AID-IJC4>3.0.CO;2-0

By:

Jäeger, Elke;
Bernhard, Helga;
Romero, Pedro;
Ringhoffer, Mark;
Arand, Michael;
Karbach, Julia;
Ilsemann, Christiane;
Hagedorn, Manfred;
Knuth, Alexander

Publication type:

Article

Tonic Inhibition in Principal Cells of the Amygdala: A Central Role for α3 Subunit-Containing GABA<sub>A</sub> Receptors.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 25, p. 8611, doi. 10.1523/JNEUROSCI.4404-11.2012

By:

Marowsky, Anne;
Rudolph, Uwe;
Fritschy, Jean-Marc;
Arand, Michael

Publication type:

Article

Identification of a CYP3A form (CYP3A126) in fathead minnow ( Pimephales promelas) and characterisation of putative CYP3A enzyme activity.

Published in:

Analytical & Bioanalytical Chemistry, 2010, v. 396, n. 2, p. 585, doi. 10.1007/s00216-009-3251-5

By:

Christen, Verena;
Caminada, Daniel;
Arand, Michael;
Fent, Karl

Publication type:

Article

Humoral immune responses of cancer patients against 'Cancer-Testis' antigen NY-ESO-1: Correlation with clinical events.

Published in:

International Journal of Cancer, 1999, v. 84, n. 5, p. 506, doi. 10.1002/(SICI)1097-0215(19991022)84:5<506::AID-IJC10>3.0.CO;2-6

By:

Jäger, Elke;
Stockert, Elisabeth;
Zidianakis, Zacharias;
Chen, Yao-Tseng;
Karbach, Julia;
Jäger, Dirk;
Arand, Michael;
Ritter, Gerd;
Old, Lloyd J.;
Knuth, Alexander

Publication type:

Article

Deep optoacoustic localization microangiography of ischemic stroke in mice.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39069-1

By:

Deán-Ben, Xosé Luís;
Robin, Justine;
Nozdriukhin, Daniil;
Ni, Ruiqing;
Zhao, Jim;
Glück, Chaim;
Droux, Jeanne;
Sendón-Lago, Juan;
Chen, Zhenyue;
Zhou, Quanyu;
Weber, Bruno;
Wegener, Susanne;
Vidal, Anxo;
Arand, Michael;
El Amki, Mohamad;
Razansky, Daniel

Publication type:

Article

Beyond detoxification: a role for mouse mEH in the hepatic metabolism of endogenous lipids.

Published in:

Archives of Toxicology, 2017, v. 91, n. 11, p. 3571, doi. 10.1007/s00204-017-2060-4

By:

Marowsky, Anne;
Meyer, Imke;
Erismann-Ebner, Kira;
Pellegrini, Giovanni;
Mule, Nandkishor;
Arand, Michael

Publication type:

Article

Evidence for a complex formation between CYP2J5 and mEH in living cells by FRET analysis of membrane protein interaction in the endoplasmic reticulum (FAMPIR).

Published in:

Archives of Toxicology, 2017, v. 91, n. 11, p. 3561, doi. 10.1007/s00204-017-2072-0

By:

Orjuela Leon, Anette;
Marwosky, Anne;
Arand, Michael

Publication type:

Article

Genetic enhancement of microsomal epoxide hydrolase improves metabolic detoxification but impairs cerebral blood flow regulation.

Published in:

Archives of Toxicology, 2016, v. 90, n. 12, p. 3017, doi. 10.1007/s00204-016-1666-2

By:

Marowsky, Anne;
Haenel, Karen;
Bockamp, Ernesto;
Heck, Rosario;
Rutishauser, Sibylle;
Mule, Nandkishor;
Kindler, Diana;
Rudin, Markus;
Arand, Michael

Publication type:

Article

International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes.

Published in:

Archives of Toxicology, 2015, v. 89, n. 2, p. 269, doi. 10.1007/s00204-015-1464-2

By:

Bal-Price, Anna;
Crofton, Kevin;
Leist, Marcel;
Allen, Sandra;
Arand, Michael;
Buetler, Timo;
Delrue, Nathalie;
FitzGerald, Rex;
Hartung, Thomas;
Heinonen, Tuula;
Hogberg, Helena;
Bennekou, Susanne;
Lichtensteiger, Walter;
Oggier, Daniela;
Paparella, Martin;
Axelstad, Marta;
Piersma, Aldert;
Rached, Eva;
Schilter, Benoît;
Schmuck, Gabriele

Publication type:

Article

Mammalian epoxide hydrolases in xenobiotic metabolism and signalling.

Published in:

Archives of Toxicology, 2009, v. 83, n. 4, p. 297, doi. 10.1007/s00204-009-0416-0

By:

Decker, Martina;
Arand, Michael;
Cronin, Annette

Publication type:

Article

Toxicological comments to the discussion about REACH.

Published in:

2006

By:

Greim, Helmut;
Arand, Michael;
Autrup, Herman;
Bolt, Hermann;
Bridges, James;
Dybing, Erik;
Glomot, Rémi;
Foa, Vito;
Schulte-Hermann, Rolf

Publication type:

Editorial

International STakeholder NETwork (ISTNET) Workshop for Creating a Developmental and Reproductive Toxicity (DART) Testing Roadmap for Regulatory Purposes.

Published in:

Altex, 2024, v. 41, n. 4, p. 671, doi. 10.14573/altex.2410081

By:

Fritsche, Ellen;
Aspiroz, Lucia Selfa;
Arand, Michael;
Faustman, Elaine;
Müller, Iris

Publication type:

Article

In-Vitro Characterization of mCerulean3_mRuby3 as a Novel FRET Pair with Favorable Bleed-Through Characteristics.

Published in:

Biosensors (2079-6374), 2019, v. 9, n. 1, p. 33, doi. 10.3390/bios9010033

By:

Erismann-Ebner, Kira;
Marowsky, Anne;
Arand, Michael

Publication type:

Article

The Telltale Structures of Epoxide Hydrolases.

Published in:

Drug Metabolism Reviews, 2003, v. 35, n. 4, p. 365, doi. 10.1081/DMR-120026498

By:

Arand, Michael;
Cronin, Annette;
Oesch, Franz;
Mowbray, Sherry L.;
Alwyn Jones, T.

Publication type:

Article

Gene Evolution of Epoxide Hydrolases and Recommended Nomenclature.

Published in:

DNA & Cell Biology, 1995, v. 14, n. 1, p. 61, doi. 10.1089/dna.1995.14.61

By:

BEETHAM, JEFFREY K.;
GRANT, DAVID;
ARAND, MICHAEL;
GARBARINO, JOAN;
KIYOSUE, TOMOHIRO;
PINOT, FRANCK;
OESCH, FRANZ;
BELKNAP, WILLIAM R.;
SHINOZAKI, KAZUO;
HAMMOCK, BRUCE D.

Publication type:

Article

Differential Toxicity of Antibodies to the Prion Protein.

Published in:

PLoS Pathogens, 2016, v. 12, n. 1, p. 1, doi. 10.1371/journal.ppat.1005401

By:

Reimann, Regina R.;
Sonati, Tiziana;
Hornemann, Simone;
Herrmann, Uli S.;
Arand, Michael;
Hawke, Simon;
Aguzzi, Adriano

Publication type:

Article