Works by Aqeilan, Rami I.

Results: 45

Unveiling the relationship between WWOX and BRCA1 in mammary tumorigenicity and in DNA repair pathway selection.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01878-8

By:

Bidany-Mizrahi, Tirza;
Shweiki, Aya;
Maroun, Kian;
Abu-Tair, Lina;
Mali, Bella;
Aqeilan, Rami I.

Publication type:

Article

Mapping the breakome reveals tight regulation on oncogenic super-enhancers.

Published in:

Molecular & Cellular Oncology, 2020, v. 7, n. 3, p. 1, doi. 10.1080/23723556.2019.1698933

By:

Oster, Sara;
Aqeilan, Rami I.

Publication type:

Article

Correction: WWOX promotes osteosarcoma development via upregulation of Myc.

Published in:

2024

By:

Akkawi, Rania;
Hidmi, Osama;
Haj-Yahia, Ameen;
Monin, Jonathon;
Diment, Judith;
Drier, Yotam;
Stein, Gary S.;
Aqeilan, Rami I.

Publication type:

Correction Notice

WWOX promotes osteosarcoma development via upregulation of Myc.

Published in:

Cell Death & Disease, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41419-023-06378-8

By:

Akkawi, Rania;
Hidmi, Osama;
Haj-Yahia, Ameen;
Monin, Jonathon;
Diment, Judith;
Drier, Yotam;
Stein, Gary S.;
Aqeilan, Rami I.

Publication type:

Article

Loss of tumor suppressor WWOX accelerates pancreatic cancer development through promotion of TGFβ/BMP2 signaling.

Published in:

Cell Death & Disease, 2022, v. 13, n. 12, p. 1, doi. 10.1038/s41419-022-05519-9

By:

Husanie, Hussam;
Abu-Remaileh, Muhannad;
Maroun, Kian;
Abu-Tair, Lina;
Safadi, Hazem;
Atlan, Karine;
Golan, Talia;
Aqeilan, Rami I.

Publication type:

Article

Fhit-Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells.

Published in:

Cell Death & Disease, 2019, v. 10, n. 3, p. 1, doi. 10.1038/s41419-019-1414-7

By:

Druck, Teresa;
Cheung, Douglas G.;
Park, Dongju;
Trapasso, Francesco;
Pichiorri, Flavia;
Gaspari, Marco;
Palumbo, Tiziana;
Aqeilan, Rami I.;
Gaudio, Eugenio;
Okumura, Hiroshi;
Iuliano, Rodolfo;
Raso, Cinzia;
Green, Kari;
Huebner, Kay;
Croce, Carlo M.

Publication type:

Article

Author Correction: WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia.

Published in:

2018

By:

Abu-Remaileh, Muhannad;
Khalaileh, Abed;
Pikarsky, Eli;
Aqeilan, Rami I.

Publication type:

Correction Notice

Somatic loss of WWOX is associated with TP53 perturbation in basal-like breast cancer.

Published in:

Cell Death & Disease, 2018, v. 9, n. 8, p. 1, doi. 10.1038/s41419-018-0896-z

By:

Abdeen, Suhaib K.;
Ben-David, Uri;
Shweiki, Aya;
Maly, Bella;
Aqeilan, Rami I.

Publication type:

Article

MicroRNA-214 promotes hepatic stellate cell activation and liver fibrosis by suppressing Sufu expression.

Published in:

Cell Death & Disease, 2018, v. 9, n. 7, p. 1, doi. 10.1038/s41419-018-0752-1

By:

Ma, Liping;
Yang, Xiaoxue;
Wei, Rong;
Ye, Tinghong;
Zhou, Jian-Kang;
Wen, Maoyao;
Men, Ruoting;
Li, Ping;
Dong, Biao;
Liu, Lunxu;
Fu, Xianghui;
Xu, Heng;
Aqeilan, Rami I.;
Wei, Yu-Quan;
Yang, Li;
Peng, Yong

Publication type:

Article

WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia.

Published in:

Cell Death & Disease, 2018, v. 9, n. 5, p. 1, doi. 10.1038/s41419-018-0510-4

By:

Abu-Remaileh, Muhannad;
Khalaileh, Abed;
Pikarsky, Eli;
Aqeilan, Rami I.

Publication type:

Article

Characterization of WWOX inactivation in murine mammary gland development.

Published in:

Journal of Cellular Physiology, 2013, v. 228, n. 7, p. 1391, doi. 10.1002/jcp.24310

By:

Abdeen, Suhaib K.;
Salah, Zaidoun;
Khawaled, Saleh;
Aqeilan, Rami I.

Publication type:

Article

Conditional inactivation of the mouse Wwox tumor suppressor gene recapitulates the null phenotype.

Published in:

Journal of Cellular Physiology, 2013, v. 228, n. 7, p. 1377, doi. 10.1002/jcp.24308

By:

Abdeen, Suhaib K.;
Del Mare, Sara;
Hussain, Sadeeq;
Abu‐Remaileh, Muhannad;
Salah, Zaidoun;
Hagan, John;
Rawahneh, Maysoon;
Pu, Xin‐an;
Russell, Stacey;
Stein, Janet L.;
Stein, Gary S.;
Lian, Jane B.;
Aqeilan, Rami I.

Publication type:

Article

Common Fragile Site Tumor Suppressor Genes and Corresponding Mouse Models of Cancer.

Published in:

Journal of Biomedicine & Biotechnology, 2011, p. 1, doi. 10.1155/2011/984505

By:

Drusco, Alessandra;
Pekarsky, Yuri;
Costinean, Stefan;
Antenucci, Anna;
Conti, Laura;
Volinia, Stefano;
Aqeilan, Rami I.;
Huebner, Kay;
Zanesi, Nicola

Publication type:

Article

Therapy of human pancreatic carcinoma based on suppression of HMGA1 protein synthesis in preclinical models.

Published in:

Cancer Gene Therapy, 2004, v. 11, n. 9, p. 633, doi. 10.1038/sj.cgt.7700745

By:

Trapasso, Francesco;
Sarti, Manuela;
Cesari, Rossano;
Yendamuri, Sai;
Dumon, Kristoffel R;
Aqeilan, Rami I.;
Pentimall, Francesca;
Infante, Luisa;
Alder, Hansjuerg;
Abe, Nobutsugu;
Watanabe, Takashi;
Viglietto, Giuseppe;
Croce, Carlo M.;
Fusco, Alfredo

Publication type:

Article

Role of the WWOX gene, encompassing fragile region FRA16D, in suppression of pancreatic carcinoma cells.

Published in:

Cancer Science, 2008, v. 99, n. 7, p. 1370, doi. 10.1111/j.1349-7006.2008.00841.x

By:

Nakayama, Shunji;
Semba, Shuho;
Maeda, Naoko;
Aqeilan, Rami I.;
Huebner, Kay;
Yokozaki, Hiroshi

Publication type:

Article

Tumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage Response.

Published in:

PLoS Genetics, 2016, v. 12, n. 12, p. 1, doi. 10.1371/journal.pgen.1006436

By:

Hazan, Idit;
Aqeilan, Rami I.;
Hofmann, Thomas G.

Publication type:

Article

TCL1A interacts with TP63 and enhances the survival of Raji Burkitt lymphoma cell line.

Published in:

British Journal of Haematology, 2018, v. 183, n. 3, p. 509, doi. 10.1111/bjh.14989

By:

Gaudio, Eugenio;
Paduano, Francesco;
Pinton, Sandra;
D'Agostino, Sabrina;
Rocca, Roberta;
Costa, Giosuè;
Ngankeu, Apollinaire;
Aqeilan, Rami I.;
Croce, Carlo M.;
Bertoni, Francesco;
Alcaro, Stefano;
Trapasso, Francesco

Publication type:

Article

Twist1-induced miR-199a-3p promotes liver fibrosis by suppressing caveolin-2 and activating TGF-β pathway.

Published in:

Signal Transduction & Targeted Therapy, 2020, v. 5, n. 1, p. 1, doi. 10.1038/s41392-020-0169-z

By:

Yang, Xiaoxue;
Ma, Liping;
Wei, Rong;
Ye, Tinghong;
Zhou, JianKang;
Wen, Maoyao;
Men, Ruoting;
Aqeilan, Rami I.;
Peng, Yong;
Yang, Li

Publication type:

Article

Pleiotropic tumor suppressor functions of WWOX antagonize metastasis.

Published in:

Signal Transduction & Targeted Therapy, 2020, v. 5, n. 1, p. 1, doi. 10.1038/s41392-020-0136-8

By:

Khawaled, Saleh;
Nigita, Giovanni;
Distefano, Rosario;
Oster, Sara;
Suh, Sung-Suk;
Smith, Yoav;
Khalaileh, Abed;
Peng, Yong;
Croce, Carlo M.;
Geiger, Tamar;
Seewaldt, Victoria L.;
Aqeilan, Rami I.

Publication type:

Article

Editorial: WW Domain Proteins in Signaling, Cancer Growth, Neural Diseases, and Metabolic Disorders.

Published in:

2019

By:

Chang, Nan-Shan;
Lin, Rongtuan;
Sze, Chun-I;
Aqeilan, Rami I.

Publication type:

Editorial

Modeling WWOX Loss of Function in vivo : What Have We Learned?

Published in:

Frontiers in Oncology, 2018, p. N.PAG, doi. 10.3389/fonc.2018.00420

By:

Tanna, Mayur;
Aqeilan, Rami I.

Publication type:

Article

RBM6 splicing factor promotes homologous recombination repair of double-strand breaks and modulates sensitivity to chemotherapeutic drugs.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 20, p. 11708, doi. 10.1093/nar/gkab976

By:

Machour, Feras E;
Abu-Zhayia, Enas R;
Awwad, Samah W;
Bidany-Mizrahi, Tirza;
Meinke, Stefan;
Bishara, Laila A;
Heyd, Florian;
Aqeilan, Rami I;
Ayoub, Nabieh

Publication type:

Article

DAZAP2 acts as specifier of the p53 response to DNA damage.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 5, p. 2759, doi. 10.1093/nar/gkab084

By:

Liebl, Magdalena C;
Moehlenbrink, Jutta;
Becker, Huong;
Raddatz, Günter;
Abdeen, Suhaib K;
Aqeilan, Rami I;
Lyko, Frank;
Hofmann, Thomas G

Publication type:

Article

Decoding the link between WWOX and p53 in aggressive breast cancer.

Published in:

Cell Cycle, 2019, v. 18, n. 11, p. 1177, doi. 10.1080/15384101.2019.1616998

By:

Abdeen, Suhaib K.;
Aqeilan, Rami I.

Publication type:

Article

The tumor suppressor WW domain-containing oxidoreductase modulates cell metabolism.

Published in:

Experimental Biology & Medicine, 2015, v. 240, n. 3, p. 345, doi. 10.1177/1535370214561956

By:

Abu-Remaileh, Muhannad;
Aqeilan, Rami I

Publication type:

Article

WW domain-containing oxidoreductase’s role in myriad cancers: Clinical significance and future implications.

Published in:

Experimental Biology & Medicine, 2014, v. 239, n. 3, p. 253, doi. 10.1177/1535370213519213

By:

Gardenswartz, Aliza;
Aqeilan, Rami I

Publication type:

Article

WWOX: Its genomics, partners, and functions.

Published in:

Journal of Cellular Biochemistry, 2009, v. 108, n. 4, p. 737, doi. 10.1002/jcb.22298

By:

Del Mare, Sara;
Salah, Zaidoun;
Aqeilan, Rami I.

Publication type:

Article

Animal models for chronic lymphocytic leukemia.

Published in:

Journal of Cellular Biochemistry, 2007, v. 100, n. 5, p. 1109, doi. 10.1002/jcb.21147

By:

Pekarsky, Yuri;
Zanesi, Nicola;
Aqeilan, Rami I.;
Croce, Carlo M.

Publication type:

Article

Tumor Suppressor WWOX inhibits osteosarcoma metastasis by modulating RUNX2 function.

Published in:

Scientific Reports, 2015, p. 12959, doi. 10.1038/srep12959

By:

Del Mare, Sara;
Aqeilan, Rami I.

Publication type:

Article

MiR‐16‐1‐3p and miR‐16‐2‐3p possess strong tumor suppressive and antimetastatic properties in osteosarcoma.

Published in:

International Journal of Cancer, 2019, v. 145, n. 11, p. 3052, doi. 10.1002/ijc.32368

By:

Maximov, Vadim V.;
Akkawi, Rania;
Khawaled, Saleh;
Salah, Zaidoun;
Jaber, Lina;
Barhoum, Ahlam;
Or, Omer;
Galasso, Marco;
Kurek, Kyle C.;
Yavin, Eylon;
Aqeilan, Rami I.

Publication type:

Article

Real-Time Non-Invasive and Direct Determination of Lactate Dehydrogenase Activity in Cerebral Organoids—A New Method to Characterize the Metabolism of Brain Organoids?

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 9, p. 878, doi. 10.3390/ph14090878

By:

Sapir, Gal;
Steinberg, Daniel J.;
Aqeilan, Rami I.;
Katz-Brull, Rachel

Publication type:

Article

Neonatal neuronal WWOX gene therapy rescues Wwox null phenotypes.

Published in:

EMBO Molecular Medicine, 2021, v. 13, n. 12, p. 1, doi. 10.15252/emmm.202114599

By:

Repudi, Srinivasarao;
Kustanovich, Irina;
Abu‐Swai, Sara;
Stern, Shani;
Aqeilan, Rami I

Publication type:

Article

Modeling genetic epileptic encephalopathies using brain organoids.

Published in:

EMBO Molecular Medicine, 2021, v. 13, n. 8, p. 1, doi. 10.15252/emmm.202013610

By:

Steinberg, Daniel J;
Repudi, Srinivasarao;
Saleem, Afifa;
Kustanovich, Irina;
Viukov, Sergey;
Abudiab, Baraa;
Banne, Ehud;
Mahajnah, Muhammad;
Hanna, Jacob H;
Stern, Shani;
Carlen, Peter L;
Aqeilan, Rami I

Publication type:

Article

Fhit Delocalizes Annexin A4 from Plasma Membrane to Cytosol and Sensitizes Lung Cancer Cells to Paclitaxel.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078610

By:

Gaudio, Eugenio;
Paduano, Francesco;
Spizzo, Riccardo;
Ngankeu, Apollinaire;
Zanesi, Nicola;
Gaspari, Marco;
Ortuso, Francesco;
Lovat, Francesca;
Rock, Jonathan;
Hill, Grace A.;
Kaou, Mohamed;
Cuda, Giovanni;
Aqeilan, Rami I.;
Alcaro, Stefano;
Croce, Carlo M.;
Trapasso, Francesco

Publication type:

Article

FHIT Suppresses Epithelial-Mesenchymal Transition (EMT) and Metastasis in Lung Cancer through Modulation of MicroRNAs.

Published in:

PLoS Genetics, 2014, v. 10, n. 10, p. 1, doi. 10.1371/journal.pgen.1004652

By:

Suh, Sung-Suk;
Yoo, Ji Young;
Cui, Ri;
Kaur, Balveen;
Huebner, Kay;
Lee, Taek-Kyun;
Aqeilan, Rami I.;
Croce, Carlo M.

Publication type:

Article

WWOX-Related Neurodevelopmental Disorders: Models and Future Perspectives.

Published in:

Cells (2073-4409), 2021, v. 10, n. 11, p. 3082, doi. 10.3390/cells10113082

By:

Steinberg, Daniel J.;
Aqeilan, Rami I.

Publication type:

Article

Neurological Disorders Associated with WWOX Germline Mutations—A Comprehensive Overview.

Published in:

Cells (2073-4409), 2021, v. 10, n. 4, p. 824, doi. 10.3390/cells10040824

By:

Banne, Ehud;
Abudiab, Baraa;
Abu-Swai, Sara;
Repudi, Srinivasa Rao;
Steinberg, Daniel J.;
Shatleh, Diala;
Alshammery, Sarah;
Lisowski, Leszek;
Gold, Wendy;
Carlen, Peter L.;
Aqeilan, Rami I.;
Kabashi, Edor

Publication type:

Article

Programmed DNA Damage and Physiological DSBs: Mapping, Biological Significance and Perturbations in Disease States.

Published in:

Cells (2073-4409), 2020, v. 9, n. 8, p. 1870, doi. 10.3390/cells9081870

By:

Oster, Sara;
Aqeilan, Rami I.

Publication type:

Article

Neuronal deletion of Wwox, associated with WOREE syndrome, causes epilepsy and myelin defects.

Published in:

2021

By:

Repudi, Srinivasarao;
Steinberg, Daniel J;
Elazar, Nimrod;
Breton, Vanessa L;
Aquilino, Mark S;
Saleem, Afifa;
Abu-Swai, Sara;
Vainshtein, Anna;
Eshed-Eisenbach, Yael;
Vijayaragavan, Bharath;
Behar, Oded;
Hanna, Jacob J;
Peles, Elior;
Carlen, Peter L;
Aqeilan, Rami I

Publication type:

journal article

Coordination of the canonical and noncanonical IKK/NF-κB signaling pathways in HTLV-I Taxmediated tumorigenesis.

Published in:

2011

By:

Jing Fu;
Zhaoxia Qu;
Pengrong Yan;
Shirong Li;
Xinxin Song;
Chie Ishikawa;
Aqeilan, Rami I.;
Mori, Naoki;
Rabson, Arnold B.;
Gutian Xiao

Publication type:

Abstract

lncRNA PVT1 in the Pathogenesis and Clinical Management of Renal Cell Carcinoma.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 5, p. 664, doi. 10.3390/biom11050664

By:

Bohosova, Julia;
Kubickova, Adela;
Slaby, Ondrej;
Uversky, Vladimir N.;
Aqeilan, Rami I.

Publication type:

Article

T538 phosphorylation, Pin-ing p63-Itch stability.

Published in:

Cell Cycle, 2015, v. 14, n. 4, p. 469, doi. 10.1080/15384101.2015.1006553

By:

Alian, Akram;
Aqeilan, Rami I

Publication type:

Article

NEDD4 E3 ligase inhibits the activity of the Hippo pathway by targeting LATS1 for degradation.

Published in:

Cell Cycle, 2013, v. 12, n. 24, p. 3817, doi. 10.4161/cc.26672

By:

Salah, Zaidoun;
Cohen, Sherri;
Itzhaki, Ella;
Aqeilan, Rami I.

Publication type:

Article

Targeted Disruption of the Murine Homeodomain-Interacting Protein Kinase-2 Causes Growth Deficiency In Vivo and Cell Cycle Arrest In Vitro.

Published in:

DNA & Cell Biology, 2009, v. 28, n. 4, p. 161, doi. 10.1089/dna.2008.0778

By:

Trapasso, Francesco;
Aqeilan, Rami I.;
Iuliano, Rodolfo;
Visone, Rosa;
Gaudio, Eugenio;
Ciuffini, Laura;
Alder, Hansjuerg;
Paduano, Francesco;
Pierantoni, Giovanna Maria;
Soddu, Silvia;
Croce, Carlo M.;
Fusco, Alfredo

Publication type:

Article

Genetic Ablation of Ptprj, a Mouse Cancer Susceptibility Gene, Results in Normal Growth and Development and Does Not Predispose to Spontaneous Tumorigenesis.

Published in:

DNA & Cell Biology, 2006, v. 25, n. 6, p. 376, doi. 10.1089/dna.2006.25.376

By:

Trapasso, Francesco;
Drusco, Alessandra;
Costinean, Stefan;
Alder, Hansjuerg;
Aqeilan, Rami I.;
Iuliano, Rodolfo;
Gaudio, Eugenio;
Raso, Cinzia;
Zanesi, Nicola;
Croce, Carlo M.;
Fusco, Alfredo

Publication type:

Article