Works by Antonetti, David A

Results: 48

Algorithm for the Measure of Vitreous Hyperreflective Foci in Optical Coherence Tomographic Scans of Patients With Diabetic Macular Edema.

Published in:

2016

By:

Korot, Edward;
Comer, Grant;
Steffens, Timothy;
Antonetti, David A.

Publication type:

journal article

Disheveled-1 Interacts with Claudin-5 and Contributes to Norrin-Induced Endothelial Barrier Restoration.

Published in:

Cells (2073-4409), 2023, v. 12, n. 19, p. 2402, doi. 10.3390/cells12192402

By:

Díaz-Coránguez, Mónica;
González-González, Laura;
Wang, Amy;
Liu, Xuwen;
Antonetti, David A.

Publication type:

Article

Dual angiopoietin‐2/VEGF‐A neutralisation prevents vascular leakage, cell death and subretinal macrophage infiltration in mouse models of retinal ischaemia/reperfusion injury and spontaneous CNV.

Published in:

Acta Ophthalmologica (1755375X), 2022, v. 100, p. N.PAG, doi. 10.1111/j.1755-3768.2022.199

By:

Canonica, Jérémie;
Shanmugam, Sumathi;
Lin, Cheng‐mao;
Antonetti, David;
Foxton, Richard;
Uhles, Sabine;
Westenkow, Peter;
Abcouwer, Steve;
Garcia Garrido, Marina

Publication type:

Article

Novel potential mechanisms for diabetic macular edema: Leveraging new investigational approaches.

Published in:

Current Diabetes Reports, 2008, v. 8, n. 4, p. 263, doi. 10.1007/s11892-008-0047-5

By:

Gardner, Thomas;
Antonetti, David

Publication type:

Article

Brain endothelial cell junctions after cerebral hemorrhage: Changes, mechanisms and therapeutic targets.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2018, v. 38, n. 8, p. 1255, doi. 10.1177/0271678X18774666

By:

Keep, Richard F.;
Andjelkovic, Anuska V.;
Xiang, Jianming;
Stamatovic, Svetlana M.;
Antonetti, David A.;
Hua, Ya;
Xi, Guohua

Publication type:

Article

Ischemia-reperfusion injury induces occludin phosphorylation/ubiquitination and retinal vascular permeability in a VEGFR-2-dependent manner.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2014, v. 34, n. 3, p. 522, doi. 10.1038/jcbfm.2013.230

By:

Muthusamy, Arivalagan;
Lin, Cheng-Mao;
Shanmugam, Sumathi;
Lindner, Heather M;
Abcouwer, Steven F;
Antonetti, David A

Publication type:

Article

“Small Blood Vessels: Big Health Problems?”: Scientific Recommendations of the National Institutes of Health Workshop.

Published in:

Journal of the American Heart Association, 2016, v. 5, n. 11, p. 1, doi. 10.1161/JAHA.116.004389

By:

Bosetti, Francesca;
Galis, Zorina S.;
Bynoe, Margaret S.;
Charette, Marc;
Cipolla, Marilyn J.;
Zoppo, Gregory J.;
Gould, Douglas;
Hatsukami, Thomas S.;
Jones, Teresa L. Z.;
Koenig, James I.;
Lutty, Gerard A.;
Maric‐Bilkan, Christine;
Stevens, Troy;
Tolunay, H. Eser;
Koroshetz, Walter;
Agalliu, Dritan;
Antonetti, David A.;
Boehm, Manfred;
Brooks, Claudette E.;
Caron, Kathleen M.

Publication type:

Article

Ocular Anti-VEGF Therapy for Diabetic Retinopathy: The Role of VEGF in the Pathogenesis of Diabetic Retinopathy.

Published in:

Diabetes Care, 2014, v. 37, n. 4, p. 893, doi. 10.2337/dc13-2002

By:

Simo, Rafael;
Sundstrom, Jeffrey M.;
Antonetti, David A.

Publication type:

Article

Targeting Neurovascular Interaction in Retinal Disorders.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 4, p. 1503, doi. 10.3390/ijms21041503

By:

Fu, Zhongjie;
Sun, Ye;
Cakir, Bertan;
Tomita, Yohei;
Huang, Shuo;
Wang, Zhongxiao;
Liu, Chi-Hsiu;
S. Cho, Steve;
Britton, William;
S. Kern, Timothy;
Antonetti, David A.;
Hellström, Ann;
E.H. Smith, Lois

Publication type:

Article

Tight Junctions in Cell Proliferation.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 23, p. 5972, doi. 10.3390/ijms20235972

By:

Díaz-Coránguez, Mónica;
Liu, Xuwen;
Antonetti, David A.

Publication type:

Article

Moving Past Anti-VEGF: Novel Therapies for Treating Diabetic Retinopathy.

Published in:

International Journal of Molecular Sciences, 2016, v. 17, n. 9, p. 1498, doi. 10.3390/ijms17091498

By:

Bolinger, Mark T.;
Antonetti, David A.

Publication type:

Article

Novel atypical PKC inhibitors prevent vascular endothelial growth factor-induced blood-retinal barrier dysfunction.

Published in:

Biochemical Journal, 2012, v. 446, n. 3, p. 455, doi. 10.1042/BJ20111961

By:

TITCHENELL, Paul M.;
LIN, Cheng-Mao;
KEIL, Jason M.;
SUNDSTROM, Jeffrey M.;
SMITH, Charles D.;
ANTONETTI, David A.

Publication type:

Article

A diet-induced mouse model for glutaric aciduria type I.

Published in:

Brain: A Journal of Neurology, 2006, v. 129, n. 4, p. 899, doi. 10.1093/brain/awl009

By:

William J. Zinnanti;
Jelena Lazovic;
Ellen B. Wolpert;
David A. Antonetti;
Michael B. Smith;
James R. Connor;
Michael Woontner;
Stephen I. Goodman;
Keith C. Cheng

Publication type:

Article

Minocycline prevents retinal inflammation and vascular permeability following ischemia-reperfusion injury.

Published in:

Journal of Neuroinflammation, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-2094-10-149

By:

Abcouwer, Steven F.;
Cheng-mao Lin;
Shanmugam, Sumathi;
Muthusamy, Arivalagan;
Barber, Alistair J.;
Antonetti, David A.

Publication type:

Article

Minocycline prevents retinal inflammation and vascular permeability following ischemia-reperfusion injury.

Published in:

2013

By:

Abcouwer, Steven F;
Lin, Cheng-Mao;
Shanmugam, Sumathi;
Muthusamy, Arivalagan;
Barber, Alistair J;
Antonetti, David A

Publication type:

journal article

DIABETIC RETINOPATHY: MOLECULAR TARGETS FOR DRUG INTERVENTION.

Published in:

Current Medical Literature: Ophthalmology, 2004, v. 14, n. 2, p. 25

By:

Barber, Alistair J.;
Antonetti, David A.

Publication type:

Article

Transgenic animal models to explore and modulate the blood brain and blood retinal barriers of the CNS.

Published in:

Fluids & Barriers of the CNS, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12987-022-00386-0

By:

Goncalves, Andreia;
Antonetti, David A.

Publication type:

Article

Occludin S471 Phosphorylation Contributes to Epithelial Monolayer Maturation.

Published in:

Molecular & Cellular Biology, 2016, v. 36, n. 15, p. 2051, doi. 10.1128/MCB.00053-16

By:

Bolinger, Mark T.;
Ramshekar, Aniket;
Waldschmidt, Helen V.;
Larsen, Scott D.;
Bewley, Maria C.;
Flanagan, John M.;
Antonetti, David A.

Publication type:

Article

Retinal pH and Acid Regulation During Metabolic Acidosis.

Published in:

Current Eye Research, 2018, v. 43, n. 7, p. 902, doi. 10.1080/02713683.2018.1458882

By:

Dreffs, Alyssa;
Antonetti, David A.;
Henderson, Desmond;
Dmitriev, Andrey V.;
Linsenmeier, Robert A.

Publication type:

Article

Glucocorticoid Regulation of Endothelial Cell Tight Junction Gene Expression: Novel Treatments for Diabetic Retinopathy.

Published in:

Current Eye Research, 2005, v. 30, n. 11, p. 949, doi. 10.1080/02713680500263598

By:

Felinski, Edward A.;
Antonetti, David A.

Publication type:

Article

Eye vessels saved by rescuing their pericyte partners.

Published in:

Nature Medicine, 2009, v. 15, n. 11, p. 1248, doi. 10.1038/nm1109-1248

By:

Antonetti, David

Publication type:

Article

A prize catch for diabetic retinopathy.

Published in:

Nature Medicine, 2007, v. 13, n. 2, p. 131, doi. 10.1038/nm0207-131

By:

Gardner, Thomas W.;
Antonetti, David A.

Publication type:

Article

Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability.

Published in:

FASEB Journal, 2015, v. 29, n. 5, p. 2194, doi. 10.1096/fj.14-269431

By:

Yunpeng Du;
Cramer, Megan;
Chieh Allen Lee;
Jie Tang;
Muthusamy, Arivalagan;
David A. Antonetti;
Hui Jin;
Palczewski, Krzysztof;
Kern, Timothy S.

Publication type:

Article

Meprin metalloproteases play a role in host response to urinary tract infection.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A279

By:

Yura, Renee Elena;
Bradley, S. Gaylen;
Antonetti, David;
Reeves, W. Brian;
Bond, Judith S.

Publication type:

Article

ELOVL4-Mediated Production of Very Long-Chain Ceramides Stabilizes Tight Junctions and Prevents Diabetes-Induced Retinal Vascular Permeability.

Published in:

Diabetes, 2018, v. 67, n. 4, p. 769, doi. 10.2337/db17-1034

By:

Kady, Nermin M.;
Xuwen Liu;
Lydic, Todd A.;
Syed, Meesum H.;
Navitskaya, Svetlana;
Qi Wang;
Hammer, Sandra S.;
O'Reilly, Sandra;
Chao Huang;
Seregin, Sergey S.;
Amalfitano, Andrea;
Chiodo, Vince A.;
Boye, Sanford L.;
Hauswirth, William W.;
Antonetti, David A.;
Busik, Julia V.

Publication type:

Article

Using the past to inform the future: anti-VEGF therapy as a road map to develop novel therapies for diabetic retinopathy.

Published in:

2013

By:

Titchenell, Paul M;
Antonetti, David A

Publication type:

journal article

Using the Past to Inform the Future: Anti-VEGF Therapy as a Road Map to Develop Novel Therapies for Diabetic Retinopathy.

Published in:

Diabetes, 2013, v. 62, n. 6, p. 1808, doi. 10.2337/db12-1744

By:

Titchenell, Paul M.;
Antonetti, David A.

Publication type:

Article

Protein kinase cβ phosphorylates occludin regulating tight junction trafficking in vascular endothelial growth factor-induced permeability in vivo.

Published in:

2012

By:

Murakami T;
Frey T;
Lin C;
Antonetti DA;
Murakami, Tomoaki;
Frey, Tiffany;
Lin, Chengmao;
Antonetti, David A

Publication type:

journal article

Protein Kinase Cβ Phosphorylates Occludin Regulating Tight Junction Trafficking in Vascular Endothelial Growth Factor--Induced Permeability In Vivo.

Published in:

Diabetes, 2012, v. 61, n. 6, p. 1573, doi. 10.2337/db11-1367

By:

Murakami, Tomoaki;
Frey, Tiffany;
Chengmao Lin;
Antonetti, David A.

Publication type:

Article

TNF-α signals through PKCζ/NF-κB to alter the tight junction complex and increase retinal endothelial cell permeability.

Published in:

2010

By:

Aveleira CA;
Lin CM;
Abcouwer SF;
Ambrósio AF;
Antonetti DA;
Aveleira, Célia A;
Lin, Cheng-Mao;
Abcouwer, Steven F;
Ambrósio, António F;
Antonetti, David A

Publication type:

journal article

TNF-α Signals Through PKCζ/NF-κB to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability.

Published in:

Diabetes, 2010, v. 59, n. 11, p. 2872, doi. 10.2337/db09-1606

By:

Aveleira, Célia A.;
Lin, Cheng-Mao;
Abcouwer, Steven F.;
Ambrósio, António F.;
Antonetti, David A.

Publication type:

Article

Ablation of 4E-BP1/2 prevents hyperglycemia-mediated induction of VEGF expression in the rodent retina and in Muller cells in culture.

Published in:

2010

By:

Schrufer TL;
Antonetti DA;
Sonenberg N;
Kimball SR;
Gardner TW;
Jefferson LS;
Schrufer, Tabitha L;
Antonetti, David A;
Sonenberg, Nahum;
Kimball, Scot R;
Gardner, Thomas W;
Jefferson, Leonard S

Publication type:

journal article

Ablation of 4E-BP1/2 Prevents Hyperglycemia-Mediated Induction of VEGF Expression in the Rodent Retina and in Müller Cells in Culture.

Published in:

Diabetes, 2010, v. 59, n. 9, p. 2107, doi. 10.2337/db10-0148

By:

Schrufer, Tabitha L.;
Antonetti, David A.;
Sonenberg, Nahum;
Kimball, Scot R.;
Gardner, Thomas W.;
Jefferson, Leonard S.

Publication type:

Article

Diabetic Retinopathy.

Published in:

Diabetes, 2006, v. 55, n. 9, p. 2401, doi. 10.2337/db05-1635

By:

Antonetti, David A.;
Barber, Alistair J.;
Bronson, Sarah K.;
Freeman, Willard M.;
Gardner, Thomas W.;
Jefferson, Leonard S.;
Kester, Mark;
Kimball, Scot R.;
Krady, J. Kyle;
LaNoue, Kathryn F.;
Norbury, Christopher C.;
Quinn, Patrick G.;
Sandirasegarane, Lakshman;
Simpson, Ian A.

Publication type:

Article

Diabetes reduces basal retinal insulin receptor signaling: reversal with systemic and local insulin.

Published in:

2006

By:

Reiter CEN;
Wu X;
Sandirasegarane L;
Nakamura M;
Gilbert KA;
Singh RSF;
Fort PE;
Antonetti DA;
Gardner TW;
Reiter, Chad E N;
Wu, Xiaohua;
Sandirasegarane, Lakshman;
Nakamura, Makoto;
Gilbert, Kirk A;
Singh, Ravi S J;
Fort, Patrice E;
Antonetti, David A;
Gardner, Thomas W

Publication type:

journal article

Diabetes Reduces Basal Retinal Insulin Receptor Signaling.

Published in:

Diabetes, 2006, v. 55, n. 4, p. 1148, doi. 10.2337/diabetes.55.04.06.db05-0744

By:

Reiter, Chad E. N.;
Gilbert, Kirk A.;
Singh, Ravi S. J.;
Fort, Patrice E.;
Antonetti, David A.;
Gardner, Thomas W.;
Wu, Xiaohua;
Nakamura, Makoto;
Sandirasegarane, Lakshman

Publication type:

Article

Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: vascular endothelial growth factor decreases occludin in retinal endothelial cells. Penn State Retina Research Group.

Published in:

1998

By:

Antonetti, David A.;
Barber, Alistair J.;
Khin, Sonny;
Lieth, Erich;
Tarbell, John M.;
Gardner, Thomas W.;
Antonetti, D A;
Barber, A J;
Khin, S;
Lieth, E;
Tarbell, J M;
Gardner, T W

Publication type:

journal article

Inflammatory resolution and vascular barrier restoration after retinal ischemia reperfusion injury.

Published in:

2021

By:

Abcouwer, Steven F.;
Shanmugam, Sumathi;
Muthusamy, Arivalagan;
Lin, Cheng-mao;
Kong, Dejuan;
Hager, Heather;
Liu, Xuwen;
Antonetti, David A.

Publication type:

journal article

DIABETIC RETINOPATHY: MOLECULAR TARGETS FOR DRUG INTERVENTION.

Published in:

Current Medical Literature: Diabetes, 2004, v. 21, n. 1, p. 1

By:

Barber, Alistair;
Antonetti, David

Publication type:

Article

Retinal neurodegeneration: early pathology in diabetes.

Published in:

Clinical & Experimental Ophthalmology, 2000, v. 28, n. 1, p. 3, doi. 10.1046/j.1442-9071.2000.00222.x

By:

Lieth, Erich;
Gardner, Thomas W;
Barber, Alistair J;
Antonetti, David A

Publication type:

Article

Molecular Mechanisms of Vascular Permeability in Diabetic Retinopathy.

Published in:

Seminars in Ophthalmology, 1999, v. 14, n. 4, p. 240, doi. 10.3109/08820539909069543

By:

Antonetti, David A.;
Lieth, Erich;
Barber, Alistair J.;
Gardner, Thomas W.

Publication type:

Article

High Glucose Attenuates Shear-Induced Changes in Endothelial Hydraulic Conductivity by Degrading the Glycocalyx.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078954

By:

Lopez-Quintero, Sandra V.;
Cancel, Limary M.;
Pierides, Alexis;
Antonetti, David;
Spray, David C.;
Tarbell, John M.

Publication type:

Article

Placenta Growth Factor-1 Exerts Time-Dependent Stabilization of Adherens Junctions Following VEGFInduced Vascular Permeability.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0018076

By:

Jun Cai;
Lin Wu;
Xiaoping Qi;
Lynn Shaw;
Sergio Li Calzi;
Sergio Caballero;
Jiang, Wen G.;
Vinores, Stanley A.;
Antonetti, David;
Ahmed, Asif;
Grant, Maria B.;
Boulton, Michael E.

Publication type:

Article

Organ-On-A-Chip Technologies for Advanced Blood-Retinal Barrier Models.

Published in:

2020

By:

Ragelle, Héloïse;
Goncalves, Andreia;
Kustermann, Stefan;
Antonetti, David A.;
Jayagopal, Ashwath

Publication type:

journal article

Pathophysiology of Diabetic Retinopathy: Contribution and Limitations of Laboratory Research.

Published in:

Ophthalmic Research, 2019, v. 62, n. 4, p. 196, doi. 10.1159/000500026

By:

Kern, Timothy S.;
Antonetti, David A.;
Smith, Lois E.H.

Publication type:

Article

Vascular Expression of Permeability-Resistant Occludin Mutant Preserves Visual Function in Diabetes.

Published in:

2021

By:

Goncalves, Andreia;
Dreffs, Alyssa;
Lin, Cheng-mao;
Sheskey, Sarah;
Hudson, Natalie;
Keil, Jason;
Campbell, Matthew;
Antonetti, David A.

Publication type:

journal article

Platelet-derived growth factor mediates tight junction redistribution and increases permeability in MDCK cells.

Published in:

Journal of Cellular Physiology, 2002, v. 193, n. 3, p. 349, doi. 10.1002/jcp.10183

By:

Harhaj, Nicole S.;
Barber, Alistair J.;
Antonetti, David A.

Publication type:

Article

Delineating effects of angiopoietin-2 inhibition on vascular permeability and inflammation in models of retinal neovascularization and ischemia/reperfusion.

Published in:

Frontiers in Cellular Neuroscience, 2023, p. 1, doi. 10.3389/fncel.2023.1192464

By:

Canonica, Jérémie;
Foxton, Richard;
Garrido, Marina Garcia;
Cheng-Mao Lin;
Uhles, Sabine;
Shanmugam, Sumathi;
Antonetti, David A.;
Abcouwer, Steven F.;
Westenskow, Peter D.

Publication type:

Article