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A first-in-human, phase 1, dose-escalation study of ABBV-176, an antibody-drug conjugate targeting the prolactin receptor, in patients with advanced solid tumors.
- Published in:
- Investigational New Drugs, 2020, v. 38, n. 6, p. 1815, doi. 10.1007/s10637-020-00960-z
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- Article
A phase 1 study evaluating safety and pharmacokinetics of losatuxizumab vedotin (ABBV-221), an anti-EGFR antibody-drug conjugate carrying monomethyl auristatin E, in patients with solid tumors likely to overexpress EGFR.
- Published in:
- Investigational New Drugs, 2020, v. 38, n. 5, p. 1483, doi. 10.1007/s10637-020-00908-3
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- Article
A phase 1 study of PARP-inhibitor ABT-767 in advanced solid tumors with BRCA1/2 mutations and high-grade serous ovarian, fallopian tube, or primary peritoneal cancer.
- Published in:
- Investigational New Drugs, 2018, v. 36, n. 5, p. 828, doi. 10.1007/s10637-017-0551-z
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- Article
Phase 1 dose escalation trial of ilorasertib, a dual Aurora/VEGF receptor kinase inhibitor, in patients with hematologic malignancies.
- Published in:
- Investigational New Drugs, 2015, v. 33, n. 4, p. 870, doi. 10.1007/s10637-015-0242-6
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- Publication type:
- Article
A phase 1 study of ABT-806 in subjects with advanced solid tumors.
- Published in:
- Investigational New Drugs, 2015, v. 33, n. 3, p. 671, doi. 10.1007/s10637-015-0234-6
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- Publication type:
- Article
The Effects of SOM230 on Cell Proliferation and Adrenocorticotropin Secretion in Human Corticotroph Pituitary Adenomas.
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- Journal of Clinical Endocrinology & Metabolism, 2006, v. 91, n. 11, p. 4482, doi. 10.1210/jc.2006-1245
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- Article
Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification.
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- 2016
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- Publication type:
- journal article
Matched cohort study of germline BRCA mutation carriers with triple negative breast cancer in brightness.
- Published in:
- NPJ Breast Cancer, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41523-021-00349-y
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- Publication type:
- Article
The ChEMBL database as linked open data.
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- Journal of Cheminformatics, 2013, v. 5, n. 1, p. 1, doi. 10.1186/1758-2946-5-23
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- Article
Defining EGFR amplification status for clinical trial inclusion.
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- Neuro-Oncology, 2019, v. 21, n. 10, p. 1263, doi. 10.1093/neuonc/noz096
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- Publication type:
- Article
Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
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- Neuro-Oncology, 2019, v. 21, n. 1, p. 106, doi. 10.1093/neuonc/noy091
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- Publication type:
- Article
Safety, pharmacokinetics, and antitumor response of depatuxizumab mafodotin as monotherapy or in combination with temozolomide in patients with glioblastoma.
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- Neuro-Oncology, 2018, v. 20, n. 6, p. 838, doi. 10.1093/neuonc/nox202
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- Publication type:
- Article
Efficacy and safety results of ABT-414 in combination with radiation and temozolomide in newly diagnosed glioblastoma.
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- Neuro-Oncology, 2017, v. 19, n. 7, p. 965, doi. 10.1093/neuonc/now257
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- Publication type:
- Article
ABBV-176, a PRLR antibody drug conjugate with a potent DNA-damaging PBD cytotoxin and enhanced activity with PARP inhibition.
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- 2021
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- Publication type:
- journal article
Clinical pharmacodynamic/exposure characterisation of the multikinase inhibitor ilorasertib (ABT-348) in a phase 1 dose-escalation trial.
- Published in:
- 2018
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- Publication type:
- journal article
A Phase 1 and Biodistribution Study of ABT-806i, An Indium-111 Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 12, p. 1, doi. 10.2967/jnumed.120.253146
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- Publication type:
- Article
A Phase 1 and Biodistribution Study of ABT-806i, An Indium-111 Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 11, p. 1, doi. 10.2967/jnumed.120.253146
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- Publication type:
- Article
A Phase 1 and Biodistribution Study of ABT-806i, An Indium-111 Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 10, p. 1, doi. 10.2967/jnumed.120.253146
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- Publication type:
- Article
A Phase 1 and Biodistribution Study of ABT-806i, An Indium-111 Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806.
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- Journal of Nuclear Medicine, 2021, v. 62, n. 8, p. 1, doi. 10.2967/jnumed.120.253146
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- Publication type:
- Article
A Phase 1 and Biodistribution Study of ABT-806i, An Indium-111 Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 7, p. 1, doi. 10.2967/jnumed.120.253146
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- Publication type:
- Article
A Phase 1 and Biodistribution Study of ABT-806i, An Indium-111 Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 6, p. 1, doi. 10.2967/jnumed.120.253146
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- Publication type:
- Article
A Phase 1 and Biodistribution Study of ABT-806i, An Indium-111 Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 5, p. 1, doi. 10.2967/jnumed.120.253146
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- Publication type:
- Article
A Phase 1 and Biodistribution Study of ABT-806i, An Indium-111 Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 3, p. 1, doi. 10.2967/jnumed.120.253146
- By:
- Publication type:
- Article
A Phase 1 and Biodistribution Study of ABT-806i, An Indium-111 Radiolabeled Conjugate of the Tumor-Specific Anti-EGFR Antibody ABT-806.
- Published in:
- Journal of Nuclear Medicine, 2021, v. 62, n. 2, p. 1, doi. 10.2967/jnumed.120.253146
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- Publication type:
- Article
An open-label, phase 1 study evaluating safety, tolerability, and pharmacokinetics of linifanib (ABT-869) in Japanese patients with solid tumors.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1477, doi. 10.1007/s00280-012-1846-6
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- Publication type:
- Article
Phase I study of anti-epidermal growth factor receptor antibody-drug conjugate serclutamab talirine: Safety, pharmacokinetics, and antitumor activity in advanced glioblastoma.
- Published in:
- Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdac183
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- Publication type:
- Article
Dynamic expression of Schlafen 11 (SLFN11) in circulating tumour cells as a liquid biomarker in small cell lung cancer.
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- 2022
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- Publication type:
- journal article
Efficacy and safety results of depatuxizumab mafodotin (ABT-414) in patients with advanced solid tumors likely to overexpress epidermal growth factor receptor.
- Published in:
- 2018
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- Publication type:
- journal article
Phase 2 trial of linifanib (ABT-869) in patients with unresectable or metastatic hepatocellular carcinoma.
- Published in:
- Cancer (0008543X), 2013, v. 119, n. 2, p. 380, doi. 10.1002/cncr.27758
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- Publication type:
- Article
Synergistic therapeutic benefit by combining the antibody drug conjugate, depatux-m with temozolomide in pre-clinical models of glioblastoma with overexpression of EGFR.
- Published in:
- Journal of Neuro-Oncology, 2021, v. 152, n. 2, p. 233, doi. 10.1007/s11060-021-03703-z
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- Publication type:
- Article
Epidermal growth factor receptor (EGFR) amplification rates observed in screening patients for randomized trials in glioblastoma.
- Published in:
- Journal of Neuro-Oncology, 2019, v. 144, n. 1, p. 205, doi. 10.1007/s11060-019-03222-y
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- Publication type:
- Article
Depatuxizumab mafodotin in EGFR-amplified newly diagnosed glioblastoma: A phase III randomized clinical trial.
- Published in:
- Neuro-Oncology, 2023, v. 25, n. 2, p. 339, doi. 10.1093/neuonc/noac173
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- Publication type:
- Article