Works by Anne J. Lenaerts

Results: 13

Intracellular and in vivo evaluation of imidazo[2,1-b]thiazole-5-carboxamide anti-tuberculosis compounds.

Published in:

PLoS ONE, 2020, v. 15, n. 1, p. 1, doi. 10.1371/journal.pone.0227224

By:

Moraski, Garrett C.;
Deboosère, Nathalie;
Marshall, Kate L.;
Weaver, Heath A.;
Vandeputte, Alexandre;
Hastings, Courtney;
Woolhiser, Lisa;
Lenaerts, Anne J.;
Brodin, Priscille;
Miller, Marvin J.

Publication type:

Article

In vitro and in vivo antimycobacterial activities of ketone and amide derivatives of quinoxaline 1,4-di-N-oxide.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2008, v. 62, n. 3, p. 547, doi. 10.1093/jac/dkn214

By:

Raquel Villar;
Esther Vicente;
Beatriz Solano;
Silvia Pérez-Silanes;
Ignacio Aldana;
Joseph A. Maddry;
Anne J. Lenaerts;
Scott G. Franzblau;
Sang-Hyun Cho;
Antonio Monge;
Robert C. Goldman

Publication type:

Article

Effects of P-MAPA Immunomodulator on Toll-Like Receptors and p53: Potential Therapeutic Strategies for Infectious Diseases and Cancer.

Published in:

Infectious Agents & Cancer, 2012, v. 7, n. 1, p. 14, doi. 10.1186/1750-9378-7-14

By:

Fávaro, Wagner J.;
Nunes, Odilon S.;
Seiva, Fabio R.F.;
Nunes, Iseu S.;
Woolhiser, Lisa K.;
Durán, Nelson;
Lenaerts, Anne J.

Publication type:

Article

Digital Image Analysis of Heterogeneous Tuberculosis Pulmonary Pathology in Non-Clinical Animal Models using Deep Convolutional Neural Networks.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-62960-6

By:

Asay, Bryce C.;
Edwards, Blake Blue;
Andrews, Jenna;
Ramey, Michelle E.;
Richard, Jameson D.;
Podell, Brendan K.;
Gutiérrez, Juan F. Muñoz;
Frank, Chad B.;
Magunda, Forgivemore;
Robertson, Gregory T.;
Lyons, Michael;
Ben-Hur, Asa;
Lenaerts, Anne J.

Publication type:

Article

Host Directed Therapy for Chronic Tuberculosis via Intrapulmonary Delivery of Aerosolized Peptide Inhibitors Targeting the IL-10-STAT3 Pathway.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-35023-0

By:

Upadhyay, Rashmi;
Sanchez-Hidalgo, Andrea;
Wilusz, Carol J.;
Lenaerts, Anne J.;
Arab, Jennifer;
Yeh, Joanna;
Stefanisko, Karen;
Tarasova, Nadya I.;
Gonzalez-Juarrero, Mercedes

Publication type:

Article

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis.

Published in:

Nature Medicine, 2013, v. 19, n. 9, p. 1157, doi. 10.1038/nm.3262

By:

Pethe, Kevin;
Bifani, Pablo;
Jang, Jichan;
Kang, Sunhee;
Park, Seijin;
Ahn, Sujin;
Jiricek, Jan;
Jung, Juyoung;
Jeon, Hee Kyoung;
Cechetto, Jonathan;
Christophe, Thierry;
Lee, Honggun;
Kempf, Marie;
Jackson, Mary;
Lenaerts, Anne J;
Pham, Ha;
Jones, Victoria;
Seo, Min Jung;
Kim, Young Mi;
Seo, Mooyoung

Publication type:

Article

Nonclinical models for antituberculosis drug development: a landscape analysis.

Published in:

2015

By:

Gumbo, Tawanda;
Lenaerts, Anne J;
Hanna, Debra;
Romero, Klaus;
Nuermberger, Eric

Publication type:

Journal Article

Pentacyclic Nitrofurans with <i>In Vivo</i> Efficacy and Activity against Nonreplicating <i>Mycobacterium tuberculosis</i>.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0087909

By:

Rakesh;
Bruhn, David F.;
Scherman, Michael S.;
Woolhiser, Lisa K.;
Madhura, Dora B.;
Maddox, Marcus M.;
Singh, Aman P.;
Lee, Robin B.;
Hurdle, Julian G.;
McNeil, Michael R.;
Lenaerts, Anne J.;
Meibohm, Bernd;
Lee, Richard E.

Publication type:

Article

Location of Intra- and Extracellular M. tuberculosis Populations in Lungs of Mice and Guinea Pigs during Disease Progression and after Drug Treatment.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0017550

By:

Hoff, Donald R.;
Ryan, Gavin J.;
Driver, Emily R.;
Ssemakulu, Cornelius C.;
De Groote, Mary A.;
Basaraba, Randall J.;
Lenaerts, Anne J.

Publication type:

Article

Multiple M. tuberculosis Phenotypes in Mouse and Guinea Pig Lung Tissue Revealed by a Dual-Staining Approach.

Published in:

PLoS ONE, 2010, v. 5, n. 6, p. 1, doi. 10.1371/journal.pone.0011108

By:

Ryan, Gavin J.;
Hoff, Donald R.;
Driver, Emily R.;
Voskuil, Martin I.;
Gonzalez-Juarrero, Mercedes;
Basaraba, Randall J.;
Crick, Dean C.;
Spencer, John S.;
Lenaerts, Anne J.

Publication type:

Article

Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane.

Published in:

Nature Chemical Biology, 2012, v. 8, n. 4, p. 334, doi. 10.1038/nchembio.794

By:

Grzegorzewicz, Anna E;
Pham, Ha;
Gundi, Vijay A K B;
Scherman, Michael S;
North, Elton J;
Hess, Tamara;
Jones, Victoria;
Gruppo, Veronica;
Born, Sarah E M;
Korduláková, Jana;
Chavadi, Sivagami Sundaram;
Morisseau, Christophe;
Lenaerts, Anne J;
Lee, Richard E;
McNeil, Michael R;
Jackson, Mary

Publication type:

Article

Spectinamides are effective partner agents for the treatment of tuberculosis in multiple mouse infection models.

Published in:

2017

By:

Robertson, Gregory T.;
Scherman, Michael S.;
Bruhn, David F.;
Liu, Jiuyu;
Hastings, Courtney;
McNeil, Michael R.;
Butler, Michelle M.;
Bowlin, Terry L.;
Lee, Robin B.;
Lee, Richard E.;
Lenaerts, Anne J.

Publication type:

journal article

In vitro and in vivo Evaluation of Synergism between Anti-Tubercular Spectinamides and Non-Classical Tuberculosis Antibiotics.

Published in:

Scientific Reports, 2015, p. 13985, doi. 10.1038/srep13985

By:

Bruhn, David F.;
Scherman, Michael S.;
Liu, Jiuyu;
Scherbakov, Dimitri;
Meibohm, Bernd;
Böttger, Erik C.;
Lenaerts, Anne J.;
Lee, Richard E.

Publication type:

Article