Works by Amour, Augustin

Results: 18

Targeting phosphoinositide 3-kinase δ for the treatment of respiratory diseases.

Published in:

Annals of the New York Academy of Sciences, 2013, v. 1280, n. 1, p. 35, doi. 10.1111/nyas.12039

By:

Sriskantharajah, Srividya;
Hamblin, Nicole;
Worsley, Sally;
Calver, Andrew R.;
Hessel, Edith M.;
Amour, Augustin

Publication type:

Article

Acute Respiratory Distress Syndrome Neutrophils Have a Distinct Phenotype and Are Resistant to Phosphoinositide 3-Kinase Inhibition.

Published in:

2016

By:

Juss, Jatinder K.;
House, David;
Amour, Augustin;
Begg, Malcolm;
Herre, Jurgen;
Storisteanu, Daniel M. L.;
Hoenderdos, Kim;
Bradley, Glyn;
Lennon, Mark;
Summers, Charlotte;
Hessel, Edith M.;
Condliffe, Alison;
Chilvers, Edwin R.

Publication type:

journal article

PI3Kδ inhibition prevents IL33, ILC2s and inflammatory eosinophils in persistent airway inflammation.

Published in:

BMC Immunology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s12865-021-00461-5

By:

Uddin, Sorif;
Amour, Augustin;
Lewis, David J.;
Edwards, Chris D.;
Williamson, Matthew G.;
Hall, Simon;
Lione, Lisa A.;
Hessel, Edith M.

Publication type:

Article

Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's β-secretase.

Published in:

Journal of Cell Biology, 2003, v. 163, n. 1, p. 97, doi. 10.1083/jcb.200303059

By:

Scholefield, Zoe;
Yates, Edwin A.;
Wayne, Gareth;
Augustin Amour, Gareth;
McDowell, William;
Turnbull, Jeremy E.

Publication type:

Article

An investigation of the anti-inflammatory effects and a potential biomarker of PI3Kδ inhibition in COPD T cells.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2017, v. 44, n. 9, p. 932, doi. 10.1111/1440-1681.12784

By:

Khan, Abid;
Southworth, Thomas;
Worsley, Sally;
Sriskantharajah, Srividya;
Amour, Augustin;
Hessel, Edith M;
Singh, Dave

Publication type:

Article

Study of bradykinin metabolism in human and rat plasma by liquid chromatography with inductively coupled plasma mass spectrometry and orthogonal acceleration time-of-flight mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2002, v. 16, n. 3, p. 220, doi. 10.1002/rcm.565

By:

Marshall, Peter;
Heudi, Olivier;
Mckeown, Stephen;
Amour, Augustin;
Abou-Shakra, Fadi

Publication type:

Article

Converging TLR9 and PI3Kgamma signaling induces sterile inflammation and organ damage.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-55504-0

By:

Lima, Braulio Henrique Freire;
Marques, Pedro Elias;
Gomides, Lindisley Ferreira;
Mattos, Matheus Silvério;
Kraemer, Lucas;
Queiroz-Junior, Celso M.;
Lennon, Mark;
Hirsch, Emilio;
Russo, Remo Castro;
Menezes, Gustavo Batista;
Hessel, Edith M.;
Amour, Augustin;
Teixeira, Mauro Martins

Publication type:

Article

Physiologically Based Pharmacokinetic Modelling of Inhaled Nemiralisib: Mechanistic Components for Pulmonary Absorption, Systemic Distribution, and Oral Absorption.

Published in:

Clinical Pharmacokinetics, 2022, v. 61, n. 2, p. 281, doi. 10.1007/s40262-021-01066-2

By:

Miller, Neil A.;
Graves, Rebecca H.;
Edwards, Chris D.;
Amour, Augustin;
Taylor, Ed;
Robb, Olivia;
O'Brien, Brett;
Patel, Aarti;
Harrell, Andrew W.;
Hessel, Edith M.

Publication type:

Article

ADAM28 is overexpressed in human non-small cell lung carcinomas and correlates with cell proliferation and lymph node metastasis.

Published in:

International Journal of Cancer, 2006, v. 118, n. 2, p. 263, doi. 10.1002/ijc.21324

By:

Ohtsuka, Takashi;
Shiomi, Takayuki;
Shimoda, Masayuki;
Kodama, Takahide;
Amour, Augustin;
Murphy, Gillian;
Ohuchi, Eiko;
Kobayashi, Koichi;
Okada, Yasunori

Publication type:

Article

The 5-Phosphatase SHIP2 Promotes Neutrophil Chemotaxis and Recruitment.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.671756

By:

Michael, Melina;
McCormick, Barry;
Anderson, Karen E.;
Karmakar, Utsa;
Vermeren, Matthieu;
Schurmans, Stéphane;
Amour, Augustin;
Vermeren, Sonja

Publication type:

Article

Investigation of Bradykinin metabolism in human and rat plasma in the presence of the dual ace/NEP inhibitors GW660511X and omapatrilat.

Published in:

Journal of Peptide Science, 2002, v. 8, n. 11, p. 591, doi. 10.1002/psc.419

By:

Heudi, Olivier;
Ramirez-Molina, Cesar;
Marshall, Peter;
Amour, Augustin;
Peace, Simon;
McKeown, Stephen;
Abou-Shakra, Fadi

Publication type:

Article

Exploring PI3Kδ Molecular Pathways in Stable COPD and Following an Acute Exacerbation, Two Randomized Controlled Trials.

Published in:

International Journal of COPD, 2021, v. 16, p. 1621, doi. 10.2147/COPD.S309303

By:

Begg, Malcolm;
Hamblin, J Nicole;
Jarvis, Emily;
Bradley, Glyn;
Mark, Stephen;
Michalovich, David;
Lennon, Mark;
Wajdner, Hannah E;
Amour, Augustin;
Wilson, Robert;
Saunders, Ken;
Tanaka, Rikako;
Arai, Saki;
Tang, Teresa;
Holsbeke, Cedric Van;
Backer, Jan De;
Vos, Wim;
Titlestad, Ingrid L;
FitzGerald, J Mark;
Killian, Kieran

Publication type:

Article

Inhibition of the Metalloproteinase Domain of Mouse TACE.

Published in:

Annals of the New York Academy of Sciences, 1999, v. 878, n. 1, p. 728, doi. 10.1111/j.1749-6632.1999.tb07774.x

By:

AMOUR, AUGUSTIN;
HUTTON, MIKE;
KNÄUPER, VERA;
SLOCOMBE, PATRICK M.;
WEBSTER, AILSA;
BUTLER, MICHAEL;
KNIGHT, C. GRAHAM;
SMITH, BRYAN J.;
DOCHERTY, ANDREW J.P.;
MURPHY, GILLIAN

Publication type:

Article

Enzyme Accessibility and Solid Supports: Which Molecular Weight Enzymes Can Be Used on Solid Supports? An Investigation Using Confocal Raman Microscopy.

Published in:

Chemistry - A European Journal, 2002, v. 8, n. 16, p. 3769, doi. 10.1002/1521-3765(20020816)8:16<3769::AID-CHEM3769>3.0.CO;2-V

By:

Kress, Jürgen;
Zanaletti, Riccardo;
Amour, Augustin;
Ladlow, Mark;
Frey, Jeremy G.;
Bradley, Mark

Publication type:

Article

The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs

Published in:

FEBS Letters, 2002, v. 524, n. 1-3, p. 154, doi. 10.1016/S0014-5793(02)03047-8

By:

Amour, Augustin;
Knight, C. Graham;
English, William R.;
Webster, Ailsa;
Slocombe, Patrick M.;
Knäuper, Vera;
Docherty, Andrew J.P.;
Becherer, J. David;
Blobel, Carl P.;
Murphy, Gillian

Publication type:

Article

The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3

Published in:

FEBS Letters, 2002, v. 520, n. 1-3, p. 102, doi. 10.1016/S0014-5793(02)02776-X

By:

Lee, Meng-Huee;
Verma, Vandana;
Maskos, Klaus;
Becherer, J. David;
Knäuper, Vera;
Dodds, Philippa;
Amour, Augustin;
Murphy, Gillian

Publication type:

Article

Organ-on-a-chip: current gaps and future directions.

Published in:

Biochemical Society Transactions, 2022, v. 50, n. 2, p. 665, doi. 10.1042/BST20200661

By:

Candarlioglu, Pelin L.;
Negro, Gianni Dal;
Hughes, David;
Balkwill, Frances;
Harris, Kate;
Screen, Hazel;
Morgan, Hywel;
David, Rhiannon;
Beken, Sonja;
Guenat, Olivier;
Rowan, Wendy;
Amour, Augustin

Publication type:

Article

Organ-on-chip applications in drug discovery: an end user perspective.

Published in:

Biochemical Society Transactions, 2021, v. 49, n. 4, p. 1881, doi. 10.1042/BST20210840

By:

Clapp, Naomi;
Amour, Augustin;
Rowan, Wendy C.;
Candarlioglu, Pelin L.

Publication type:

Article