Works by Ambudkar, Suresh V.
Results: 65
Prolonged Drug Selection of Breast Cancer Cells and Enrichment of Cancer Stem Cell Characteristics.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2010, v. 102, n. 21, p. 1637, doi. 10.1093/jnci/djq361
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- Publication type:
- Article
Design, Synthesis and Biological Evaluation of Quinazolinamine Derivatives as Breast Cancer Resistance Protein and P-Glycoprotein Inhibitors with Improved Metabolic Stability.
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- Biomolecules (2218-273X), 2023, v. 13, n. 2, p. 253, doi. 10.3390/biom13020253
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- Publication type:
- Article
Characterization of the Lipidome and Biophysical Properties of Membranes from High Five Insect Cells Expressing Mouse P-Glycoprotein.
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- Biomolecules (2218-273X), 2021, v. 11, n. 3, p. 426, doi. 10.3390/biom11030426
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- Publication type:
- Article
Glesatinib, a c-MET/SMO Dual Inhibitor, Antagonizes P-glycoprotein Mediated Multidrug Resistance in Cancer Cells.
- Published in:
- Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00313
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- Publication type:
- Article
Correction: Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood–brain barrier.
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- 2025
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- Publication type:
- Correction Notice
Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood–brain barrier.
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- Fluids & Barriers of the CNS, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12987-024-00529-5
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- Publication type:
- Article
Structure of a multidrug transporter.
- Published in:
- Nature Biotechnology, 2009, v. 27, n. 6, p. 546, doi. 10.1038/nbt0609-546
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- Publication type:
- Article
The glucose-6-phosphate transporter is a phosphate-linked antiporter deficient in glycogen storage disease type Ib and Ic.
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- FASEB Journal, 2008, v. 22, n. 7, p. 2206, doi. 10.1096/fj.07-104851
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- Publication type:
- Article
ATP-driven dimerization of nucleotide binding domains, asymmetric occlusion of one nucleotide and ADP-driven disassembly of the occluded state are important reaction intermediates of the P-glycoprotein transport cycle.
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- FASEB Journal, 2007, v. 21, n. 5, p. A242, doi. 10.1096/fasebj.21.5.a242-b
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- Publication type:
- Article
PBK/TOPK inhibitor OTS964 resistance is mediated by ABCB1-dependent transport function in cancer: in vitro and in vivo study.
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- Molecular Cancer, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12943-022-01512-0
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- Publication type:
- Article
ATP-dependent thermostabilization of human P-glycoprotein (ABCB1) is blocked by modulators.
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- Biochemical Journal, 2019, v. 476, n. 24, p. 3737, doi. 10.1042/BCJ20190736
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- Publication type:
- Article
Nonsynonymous Mutations in Linker-2 of the Pdr5 Multidrug Transporter Identify a New RNA Stability Element.
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- G3: Genes | Genomes | Genetics, 2020, v. 10, n. 1, p. 257, doi. 10.1534/g3.119.400863
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- Publication type:
- Article
Polyoxovanadates as new P-glycoprotein inhibitors: insights into the mechanism of inhibition.
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- FEBS Letters, 2022, v. 596, n. 3, p. 381, doi. 10.1002/1873-3468.14265
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- Publication type:
- Article
Does the ATP‐bound EQ mutant reflect the pre‐ or post‐ATP hydrolysis state in the catalytic cycle of human P‐glycoprotein (ABCB1)?
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- FEBS Letters, 2021, v. 595, n. 6, p. 750, doi. 10.1002/1873-3468.14054
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- Publication type:
- Article
Design, Synthesis, and Biological Evaluation of ( S)-Valine Thiazole-Derived Cyclic and Noncyclic Peptidomimetic Oligomers as Modulators of Human P-Glycoprotein (ABCB1).
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- ChemBioChem, 2014, v. 15, n. 1, p. 157, doi. 10.1002/cbic.201300565
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- Publication type:
- Article
ABCB1 and ABCG2 Overexpression Mediates Resistance to the Phosphatidylinositol 3-Kinase Inhibitor HS-173 in Cancer Cell Lines.
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- Cells (2073-4409), 2023, v. 12, n. 7, p. 1056, doi. 10.3390/cells12071056
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- Publication type:
- Article
Association of the ABCG2 C421A polymorphism with prostate cancer risk and survival.
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- BJU International, 2008, v. 102, n. 11, p. 1694, doi. 10.1111/j.1464-410X.2008.07913.x
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- Publication type:
- Article
Emerging nanotechnology-based therapeutics to combat multidrug-resistant cancer.
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- 2022
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- Publication type:
- Literature Review
Ion Extrusion Systems in Bacteria.
- Published in:
- Annals of the New York Academy of Sciences, 1985, v. 456, n. 1, p. 235, doi. 10.1111/j.1749-6632.1985.tb14870.x
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- Publication type:
- Article
Anion Exchange in Bacteria Variable.
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- Annals of the New York Academy of Sciences, 1985, v. 456, n. 1, p. 245, doi. 10.1111/j.1749-6632.1985.tb14871.x
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- Publication type:
- Article
The multidrug transporter Pdr5 on the 25th anniversary of its discovery: an important model for the study of asymmetric ABC transporters.
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- Biochemical Journal, 2015, v. 467, n. 3, p. 353, doi. 10.1042/BJ20150042
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- Publication type:
- Article
Identification of a Cryptic Bacterial Promoter in Mouse (mdr1a) P-Glycoprotein cDNA.
- Published in:
- PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0136396
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- Publication type:
- Article
ARRY-334543 Reverses Multidrug Resistance by Antagonizing the Activity of ATP-Binding Cassette Subfamily G Member 2.
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- Journal of Cellular Biochemistry, 2014, v. 115, n. 8, p. 1381, doi. 10.1002/jcb.24787
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- Publication type:
- Article
Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-03500-8
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- Publication type:
- Article
The A-loop, a novel conserved aromatic acid subdomain upstream of the Walker A motif in ABC transporters, is critical for ATP binding
- Published in:
- FEBS Letters, 2006, v. 580, n. 4, p. 1049, doi. 10.1016/j.febslet.2005.12.051
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- Publication type:
- Article
Thiazole-valine peptidomimetic (TTT-28) antagonizes multidrug resistance in vitro and in vivo by selectively inhibiting the efflux activity of ABCB1.
- Published in:
- Scientific Reports, 2017, p. 42106, doi. 10.1038/srep42106
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- Publication type:
- Article
Tetrahydroquinoline/4,5‐Dihydroisoxazole Molecular Hybrids as Inhibitors of Breast Cancer Resistance Protein (BCRP/ABCG2).
- Published in:
- ChemMedChem, 2021, v. 16, n. 17, p. 2686, doi. 10.1002/cmdc.202100188
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- Publication type:
- Article
ABCG2 Mediates Resistance to the Dual EGFR and PI3K Inhibitor MTX-211 in Cancer Cells.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 10, p. 5160, doi. 10.3390/ijms25105160
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- Publication type:
- Article
Furmonertinib, a Third-Generation EGFR Tyrosine Kinase Inhibitor, Overcomes Multidrug Resistance through Inhibiting ABCB1 and ABCG2 in Cancer Cells.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 13972, doi. 10.3390/ijms241813972
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- Publication type:
- Article
Hydroxygenkwanin Improves the Efficacy of Cytotoxic Drugs in ABCG2-Overexpressing Multidrug-Resistant Cancer Cells.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 12763, doi. 10.3390/ijms232112763
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- Publication type:
- Article
A Phenylfurocoumarin Derivative Reverses ABCG2-Mediated Multidrug Resistance In Vitro and In Vivo.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 22, p. 12502, doi. 10.3390/ijms222212502
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- Publication type:
- Article
Overexpression of Human ABCB1 and ABCG2 Reduces the Susceptibility of Cancer Cells to the Histone Deacetylase 6-Specific Inhibitor Citarinostat.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2592, doi. 10.3390/ijms22052592
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- Publication type:
- Article
The Selective Class IIa Histone Deacetylase Inhibitor TMP195 Resensitizes ABCB1- and ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Cytotoxic Anticancer Drugs.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 1, p. 238, doi. 10.3390/ijms21010238
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- Publication type:
- Article
Mapping discontinuous epitopes for MRK-16, UIC2 and 4E3 antibodies to extracellular loops 1 and 4 of human P-glycoprotein.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-30984-8
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- Publication type:
- Article
Use of photoimmunoconjugates to characterize ABCB1 in cancer cells.
- Published in:
- Nanophotonics (21928606), 2021, v. 10, n. 12, p. 3049, doi. 10.1515/nanoph-2021-0252
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- Publication type:
- Article
Saracatinib (AZD0530) is a potent modulator of ABCB1-mediated multidrug resistance in vitro and in vivo.
- Published in:
- International Journal of Cancer, 2013, v. 132, n. 1, p. 224, doi. 10.1002/ijc.27649
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- Publication type:
- Article
Characterization of Potent ABCG2 Inhibitor Derived from Chromone: From the Mechanism of Inhibition to Human Extracellular Vesicles for Drug Delivery.
- Published in:
- Pharmaceutics, 2023, v. 15, n. 4, p. 1259, doi. 10.3390/pharmaceutics15041259
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- Publication type:
- Article
Interaction of a Homologous Series of Amphiphiles with P-glycoprotein in a Membrane Environment—Contributions of Polar and Non-Polar Interactions.
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- Pharmaceutics, 2023, v. 15, n. 1, p. 174, doi. 10.3390/pharmaceutics15010174
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- Publication type:
- Article
Imperatorin Restores Chemosensitivity of Multidrug-Resistant Cancer Cells by Antagonizing ABCG2-Mediated Drug Transport.
- Published in:
- Pharmaceuticals (14248247), 2023, v. 16, n. 11, p. 1595, doi. 10.3390/ph16111595
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- Publication type:
- Article
Becatecarin (rebeccamycin analog, NSC 655649) is a transport substrate and induces expression of the ATP-binding cassette transporter, ABCG2, in lung carcinoma cells.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2009, v. 64, n. 3, p. 575, doi. 10.1007/s00280-008-0908-2
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- Publication type:
- Article
Differential effects of the immunosuppressive agents cyclosporin A, tacrolimus and sirolimus on drug transport by multidrug resistance proteins.
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- Cancer Chemotherapy & Pharmacology, 2007, v. 60, n. 2, p. 179, doi. 10.1007/s00280-006-0357-8
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- Publication type:
- Article
Differential effects of the immunosuppressive agents cyclosporin A, tacrolimus and sirolimus on drug transport by multidrug resistance proteins.
- Published in:
- 2007
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- Publication type:
- journal article
Curcuminoids purified from turmeric powder modulate the function of human multidrug resistance protein 1 (ABCC1).
- Published in:
- 2006
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- Publication type:
- journal article
An A666G mutation in transmembrane helix 5 of the yeast multidrug transporter Pdr5 increases drug efflux by enhancing cooperativity between transport sites.
- Published in:
- Molecular Microbiology, 2019, v. 112, n. 4, p. 1131, doi. 10.1111/mmi.14351
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- Publication type:
- Article
Residues from Homologous Transmembrane Helices 4 and 10 Are Critical for P-Glycoprotein (ABCB1)-Mediated Drug Transport.
- Published in:
- Cancers, 2023, v. 15, n. 13, p. 3459, doi. 10.3390/cancers15133459
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- Publication type:
- Article
P-glycoprotein Mediates Resistance to the Anaplastic Lymphoma Kinase Inhiitor Ensartinib in Cancer Cells.
- Published in:
- Cancers, 2022, v. 14, n. 9, p. N.PAG, doi. 10.3390/cancers14092341
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- Publication type:
- Article
BMS-599626, a Highly Selective Pan-HER Kinase Inhibitor, Antagonizes ABCG2-Mediated Drug Resistance.
- Published in:
- Cancers, 2020, v. 12, n. 9, p. 2502, doi. 10.3390/cancers12092502
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- Publication type:
- Article
Tivantinib, A c-Met Inhibitor in Clinical Trials, Is Susceptible to ABCG2-Mediated Drug Resistance.
- Published in:
- Cancers, 2020, v. 12, n. 1, p. 186, doi. 10.3390/cancers12010186
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- Publication type:
- Article
South Asian Medicinal Compounds as Modulators of Resistance to Chemotherapy and Radiotherapy.
- Published in:
- Cancers, 2016, v. 8, n. 3, p. 32, doi. 10.3390/cancers8030032
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- Publication type:
- Article
Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5).
- Published in:
- FEBS Journal, 2005, v. 272, n. 18, p. 4725, doi. 10.1111/j.1742-4658.2005.04888.x
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- Publication type:
- Article