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The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington's disease.
- Published in:
- BMC Research Notes, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s13104-020-05053-x
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- Publication type:
- Article
Emoções em Experiências Negativas de Turismo: um estudo sobre a influência na insatisfação.
- Published in:
- Revista Turismo em Análise, 2015, v. 26, n. 1, p. 188, doi. 10.11606/issn.1984-4867.v26i1p188-215
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- Publication type:
- Article
Neuronal Cholesterol Accumulation Induced by Cyp46a1 Down-Regulation in Mouse Hippocampus Disrupts Brain Lipid Homeostasis.
- Published in:
- Frontiers in Molecular Neuroscience, 2017, p. 1, doi. 10.3389/fnmol.2017.00211
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- Publication type:
- Article
Reply: Beneficial effect of interleukin-2-based immunomodulation in Alzheimer-like pathology.
- Published in:
- 2017
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- Publication type:
- Letter
Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer's disease mice.
- Published in:
- 2017
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- Publication type:
- journal article
CYP46A1, the rate-limiting enzyme for cholesterol degradation, is neuroprotective in Huntington's disease.
- Published in:
- 2016
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- Publication type:
- journal article
CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease.
- Published in:
- 2015
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- Publication type:
- journal article
O5‐06‐04: AAV‐CYP46A1 BRAIN DELIVERY MITIGATES ALZHEIMER'S DISEASE: FROM MOUSE MODELS TO NON‐HUMAN PRIMATES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1658, doi. 10.1016/j.jalz.2018.06.3028
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- Publication type:
- Article
RESPOSTAS DE BIOMARCADORES MUSCULARES A UMA PARTIDA DE FUTEBOL.
- Published in:
- Revista Brasileira de Futsal e Futebol, 2014, v. 6, n. 19, p. 58
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- Publication type:
- Article
ADESÃO E QUALIDADE DE VIDA DOS JOVENS ADULTOS EM TRATAMENTO DE HEMODIÁLISE.
- Published in:
- RECIEN: Revista Científica de Enfermagem, 2023, v. 13, n. 41, p. 125, doi. 10.24276/rrecien2023.13.41.125-134
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- Publication type:
- Article
SURVIVAL MECHANISMS OF Fusarium oxysporum f. sp. passiflorae ARE AFFECTED BY APPLICATION OF CABBAGE AND CASSAVA DEBRIS.
- Published in:
- Revista Caatinga, 2022, v. 35, n. 3, p. 586, doi. 10.1590/1983-21252022v35n309rc
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- Publication type:
- Article
Editorial: Gene Silencing and Editing Strategies for Neurodegenerative Diseases.
- Published in:
- Frontiers in Neuroscience, 2018, p. 1, doi. 10.3389/fnins.2018.00425
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- Publication type:
- Article
CONTRAST-ENHANCED MR MICROSCOPY OF AMYLOID PLAQUES IN FIVE MOUSE MODELS OF ALZHEIMER'S DISEASE: COMPARISON WITH AMYLOID PLAQUE DETECTION IN HUMAN BRAINS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P920, doi. 10.1016/j.jalz.2017.07.351
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- Publication type:
- Article
Gene transfer of both app and ps1 induces hippocampal impairments close to human early phases of Alzheimer’s disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P351, doi. 10.1016/j.jalz.2015.06.233
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- Publication type:
- Article
Hippocampal CYP46A1 overexpression is beneficial in rodent models of Alzheimer’s disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P758, doi. 10.1016/j.jalz.2015.06.1691
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- Publication type:
- Article
Corrigendum: Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7.
- Published in:
- Nature Structural & Molecular Biology, 2015, v. 22, n. 3, p. 272, doi. 10.1038/nsmb0315-272b
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- Publication type:
- Article
Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7.
- Published in:
- Nature Structural & Molecular Biology, 2014, v. 21, n. 11, p. 955, doi. 10.1038/nsmb.2902
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- Publication type:
- Article
Ultramicroscopy as a novel tool to unravel the tropism of AAV gene therapy vectors in the brain.
- Published in:
- Scientific Reports, 2016, p. 28272, doi. 10.1038/srep28272
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- Publication type:
- Article
Léxico, Cultura e Ensino: o patrimônio imaterial no Museu da Gente Sergipana.
- Published in:
- Saeculum - Revista de História (0104-8929), 2022, v. 27, n. 46, p. 285, doi. 10.22478/ufpb.2317-6725.2022v27n46.62591
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- Publication type:
- Article
Allele-Specific RNA Silencing of Mutant Ataxin-3 Mediates Neuroprotection in a Rat Model of Machado-Joseph Disease.
- Published in:
- PLoS ONE, 2008, v. 3, n. 10, p. 1, doi. 10.1371/journal.pone.0003341
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- Publication type:
- Article
Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice.
- Published in:
- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0678-6
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- Publication type:
- Article
Does the satisfaction of psychological needs predict the development of life skills in dual-career athletes?
- Published in:
- Motricidade, 2023, v. 19, n. 1, p. 86, doi. 10.6063/motricidade.27358
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- Publication type:
- Article
Correlation between microstructure and corrosion behavior in an AISI 316L steel pipeline exposed for 100,700 h at 640°C in a petrochemical plant.
- Published in:
- Materials & Corrosion / Werkstoffe und Korrosion, 2021, v. 72, n. 11, p. 1762, doi. 10.1002/maco.202112517
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- Publication type:
- Article
A viagem que mais contribuiu para quem eu sou: explorando as dimensões da Experiência Turística Eudaimônica.
- Published in:
- Revista Brasileira de Pesquisa em Turismo, 2020, v. 14, n. 1, p. 14, doi. 10.7784/rbtur.v14i1.1599
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- Publication type:
- Article
Interferon beta induces clearance of mutant ataxin 7 and improves locomotion in SCA7 knock-in mice.
- Published in:
- Brain: A Journal of Neurology, 2013, v. 136, n. 6, p. 1732, doi. 10.1093/brain/awt061
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- Publication type:
- Article
Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease.
- Published in:
- 2011
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- Publication type:
- journal article
Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado–Joseph disease.
- Published in:
- Brain: A Journal of Neurology, 2011, v. 134, n. 5, p. 1400, doi. 10.1093/brain/awr047
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- Publication type:
- Article
ARQUEOLOGÍA, OCUPACIONES CAZADORAS-RECOLECTORAS Y EL CERRADO DEL BRASIL CENTRAL: PROPOSICIÓN DE UN MODELO SOCIOCULTURAL Y ECONÓMICO EN CORRELACIÓN CON LOS PUEBLOS CONTEMPORÁNEOS DE LOS BOSQUES TROPICALES.
- Published in:
- Arqueología Iberoamericana, 2024, v. 53, p. 61
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- Publication type:
- Article
Sustained effects of nonallele-specific Huntingtin silencing.
- Published in:
- Annals of Neurology, 2009, v. 65, n. 3, p. 276, doi. 10.1002/ana.21569
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- Publication type:
- Article
Determinação do risco potencial de interações medicamentosas prolongadoras do intervalo QT em idosos internados em unidade de terapia intensiva.
- Published in:
- Revista Colombiana de Ciencias Químico-Farmacéuticas, 2022, v. 51, n. 2, p. 881, doi. 10.15446/rcciquifa.v51n2.98897
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- Publication type:
- Article
Development of a Root Colonization Bioassay for Rapid Screening of Rhizobacteria for Potential Biocontrol Agents.
- Published in:
- Journal of Phytopathology, 2003, v. 151, n. 1, p. 42, doi. 10.1046/j.1439-0434.2003.00678.x
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- Publication type:
- Article
βAPP Processing Drives Gradual Tau Pathology in an Age-Dependent Amyloid Rat Model of Alzheimer's Disease.
- Published in:
- Cerebral Cortex, 2018, v. 28, n. 11, p. 3976, doi. 10.1093/cercor/bhx260
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- Publication type:
- Article
Modulation of Brain Cholesterol Metabolism through CYP46A1 Overexpression for Rett Syndrome.
- Published in:
- Pharmaceutics, 2024, v. 16, n. 6, p. 756, doi. 10.3390/pharmaceutics16060756
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- Publication type:
- Article
Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia.
- Published in:
- Acta Neuropathologica, 2019, v. 138, n. 5, p. 837, doi. 10.1007/s00401-019-02019-7
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- Publication type:
- Article
The autophagy/lysosome pathway is impaired in SCA7 patients and SCA7 knock-in mice.
- Published in:
- Acta Neuropathologica, 2014, v. 128, n. 5, p. 705, doi. 10.1007/s00401-014-1289-8
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- Publication type:
- Article
Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins.
- Published in:
- Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0123-2
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- Publication type:
- Article
Alzheimer's disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression.
- Published in:
- Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0070-y
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- Publication type:
- Article
Basic Psychological Needs and Sports Satisfaction Among Brazilian Athletes and Coaches: The Mediating Role of the Dyadic Relationship.
- Published in:
- Frontiers in Psychology, 2019, p. 1, doi. 10.3389/fpsyg.2019.02543
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- Publication type:
- Article
Silencing ataxin-3 mitigates degeneration in a rat model of Machado–Joseph disease: no role for wild-type ataxin-3?
- Published in:
- Human Molecular Genetics, 2010, v. 19, n. 12, p. 2380, doi. 10.1093/hmg/ddq111
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- Publication type:
- Article
Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease.
- Published in:
- Human Molecular Genetics, 2008, v. 17, n. 14, p. 2071, doi. 10.1093/hmg/ddn106
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- Publication type:
- Article
Life skills and basic psychological needs of university athletes.
- Published in:
- Saúde e Pesquisa, 2022, v. 15, n. 4, p. 1, doi. 10.17765/2176-9206.2022v15n4.e10917
- By:
- Publication type:
- Article
Capturing eudaimonic feelings in tourism experience: A construct proposal and preliminary empirical evidence.
- Published in:
- Tourism & Hospitality Research, 2024, v. 24, n. 4, p. 636, doi. 10.1177/14673584231173512
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- Publication type:
- Article
Deregulation of autophagy in postmortem brains of Machado‐Joseph disease patients.
- Published in:
- Neuropathology, 2018, v. 38, n. 2, p. 113, doi. 10.1111/neup.12433
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- Publication type:
- Article
Birds from human-modified Atlantic Forest landscapes of the middle-lower Paraíba do Sul River basin, southeastern Brazil.
- Published in:
- Check List, 2024, v. 20, n. 3, p. 778, doi. 10.15560/20.3.778
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- Publication type:
- Article
Medium-sized and large mammals of the Floresta da Cicuta Area of Relevant Ecological Interest, a protected area in southeastern Brazil.
- Published in:
- Check List, 2021, v. 17, n. 5, p. 1421, doi. 10.15560/17.5.1421
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- Publication type:
- Article