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A Patient‐to‐Model‐to‐Patient (PMP) Cancer Drug Discovery Protocol for Identifying and Validating Therapeutic Agents Targeting Tumor Regulatory Architecture.
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- Current Protocols, 2022, v. 2, n. 9, p. 1, doi. 10.1002/cpz1.544
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- Article
A model for network-based identification and pharmacological targeting of aberrant, replication-permissive transcriptional programs induced by viral infection.
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- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03663-8
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- Article
A phase 1 clinical trial of oral eltanexor in patients with relapsed or refractory multiple myeloma.
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- American Journal of Hematology, 2022, v. 97, n. 2, p. E54, doi. 10.1002/ajh.26420
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- Article
Systematic elucidation of neuron-astrocyte interaction in models of amyotrophic lateral sclerosis using multi-modal integrated bioinformatics workflow.
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- Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19177-y
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- Article
Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05729-w
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- Article
Quantitative assessment of protein activity in orphan tissues and single cells using the metaVIPER algorithm.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03843-3
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- Article
Systematic, network-based characterization of therapeutic target inhibitors.
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- PLoS Computational Biology, 2017, v. 13, n. 10, p. 1, doi. 10.1371/journal.pcbi.1005599
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- Article
PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens.
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- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00136-z
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- Article
A case study of an integrative genomic and experimental therapeutic approach for rare tumors: identification of vulnerabilities in a pediatric poorly differentiated carcinoma.
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- Genome Medicine, 2016, v. 8, p. 1, doi. 10.1186/s13073-016-0366-0
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- Article
Detection and removal of spatial bias in multiwell assays.
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- Bioinformatics, 2016, v. 32, n. 13, p. 1959, doi. 10.1093/bioinformatics/btw092
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DIGGIT: a Bioconductor package to infer genetic variants driving cellular phenotypes.
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- Bioinformatics, 2015, v. 31, n. 24, p. 4032, doi. 10.1093/bioinformatics/btv499
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- Article
Identification of neurodegenerative factors using translatome-regulatory network analysis.
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- Nature Neuroscience, 2015, v. 18, n. 9, p. 1325, doi. 10.1038/nn.4070
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- Article
SPARC Controls Melanoma Cell Plasticity through Rac1.
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- PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0134714
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- Article
Interrogation of a Context-Specific Transcription Factor Network Identifies Novel Regulators of Pluripotency.
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- Stem Cells, 2015, v. 33, n. 2, p. 367, doi. 10.1002/stem.1870
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A community computational challenge to predict the activity of pairs of compounds.
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- Nature Biotechnology, 2014, v. 32, n. 12, p. 1213, doi. 10.1038/nbt.3052
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- Article
Improving Breast Cancer Survival Analysis through Competition-Based Multidimensional Modeling
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- PLoS Computational Biology, 2013, v. 9, n. 5, p. 1, doi. 10.1371/journal.pcbi.1003047
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- Article
PFT1, the MED25 subunit of the plant Mediator complex, promotes flowering through CONSTANS dependent and independent mechanisms in Arabidopsis.
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- Plant Journal, 2012, v. 69, n. 4, p. 601, doi. 10.1111/j.1365-313X.2011.04815.x
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- Article
A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers.
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- Molecular Systems Biology, 2010, v. 6, n. 1, p. 1, doi. 10.1038/msb.2010.31
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- Article
Genome-wide identification of post-translational modulators of transcription factor activity in human B cells.
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- Nature Biotechnology, 2009, v. 27, n. 9, p. 829, doi. 10.1038/nbt.1563
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- Article
A complementary role for ELF3 and TFL1 in the regulation of flowering time by ambient temperature.
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- Plant Journal, 2009, v. 58, n. 4, p. 629, doi. 10.1111/j.1365-313X.2009.03811.x
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- Article
SPARC Endogenous Level, rather than Fibroblast-Produced SPARC or Stroma Reorganization Induced by SPARC, Is Responsible for Melanoma Cell Growth.
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- Journal of Investigative Dermatology, 2007, v. 127, n. 11, p. 2618, doi. 10.1038/sj.jid.5700962
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- Article
Platelet‐endothelial cell adhesion molecule‐1 (CD31) recycles and induces cell growth inhibition on human tumor cell lines.
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- Journal of Cellular Biochemistry, 2006, v. 98, n. 5, p. 1334, doi. 10.1002/jcb.20769
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- Article