Works by Altmann, Karl‐Heinz
Results: 100
Cover Feature: Experimental and Theoretical Studies on the Reactions of Aliphatic Imines with Isocyanates (Chem. Eur. J. 14/2024).
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- 2024
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- Correction Notice
Experimental and Theoretical Studies on the Reactions of Aliphatic Imines with Isocyanates.
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- Chemistry - A European Journal, 2024, v. 30, n. 14, p. 1, doi. 10.1002/chem.202304272
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- Article
Cover Feature: Synthesis and Structure‐Activity Relationship Studies of C(13)‐Desmethylene‐(−)‐Zampanolide Analogs (Chem. Eur. J. 36/2023).
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- Chemistry - A European Journal, 2023, v. 29, n. 36, p. 1, doi. 10.1002/chem.202301652
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- Article
Synthesis and Structure‐Activity Relationship Studies of C(13)‐Desmethylene‐(−)‐Zampanolide Analogs.
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- Chemistry - A European Journal, 2023, v. 29, n. 36, p. 1, doi. 10.1002/chem.202300703
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- Article
Die Totalsynthese von Isoxeniolid A**.
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- Angewandte Chemie, 2024, v. 136, n. 9, p. 1, doi. 10.1002/ange.202315423
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- Article
Synthese und Biologische Untersuchungen von C(13)/C(13′)‐Bis(desmethyl)disorazol Z**.
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- Angewandte Chemie, 2023, v. 135, n. 5, p. 1, doi. 10.1002/ange.202212190
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- Article
Die Totalsynthese des Antibiotikums Disciformycin B durch Ringschlussmetathese.
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- Angewandte Chemie, 2020, v. 132, n. 40, p. 17546, doi. 10.1002/ange.202004589
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Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter.
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- Cell Discovery, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41421-021-00247-4
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- Article
STUDIES OF A CHEMICALLY MODIFIED OLIGODEOXYNUCLEOTIDE CONTAINING A 5-ATOM AMIDE BACKBONE WHICH EXHIBITS IMPROVED BINDING TO RNA.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 991, doi. 10.1081/NCN-100002475
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- Article
The Chemistry and Biology of Epothilones-The Wheel Keeps Turning.
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- ChemMedChem, 2007, v. 2, n. 4, p. 396, doi. 10.1002/cmdc.200600206
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- Article
Structure-Activity Relationships in Side-Chain-Modified Epothilone Analogues-How Important is the Position of the Nitrogen Atom?
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- ChemMedChem, 2006, v. 1, n. 1, p. 37, doi. 10.1002/cmdc.200500051
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- Article
Total Synthesis of the Bacterial RNA Polymerase Inhibitor Ripostatin B.
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- Angewandte Chemie International Edition, 2012, v. 51, n. 14, p. 3405, doi. 10.1002/anie.201200871
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- Article
Immunosuppressive Small Molecule Discovered by Structure-Based Virtual Screening for Inhibitors of Protein-Protein Interactions.
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- Angewandte Chemie International Edition, 2012, v. 51, n. 1, p. 258, doi. 10.1002/anie.201105901
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- Article
Treasures from the Sea: Discovery and Total Synthesis of Ammosamides.
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- Angewandte Chemie International Edition, 2010, v. 49, n. 39, p. 6936, doi. 10.1002/anie.201002788
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- Article
Total Synthesis of the Marine Diterpenoid Blumiolide C.
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- Angewandte Chemie International Edition, 2008, v. 47, n. 52, p. 10081, doi. 10.1002/anie.200804004
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Contextual Compound Screening for Improved Therapeutic Discovery.
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- ChemBioChem, 2013, v. 14, n. 18, p. 2512, doi. 10.1002/cbic.201300409
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- Article
Cover Picture: Making Epothilones Fluoresce: Design, Synthesis, and Biological Characterization of a Fluorescent N12-Aza-Epothilone (Azathilone) (ChemBioChem 15/2009).
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- ChemBioChem, 2009, v. 10, n. 15, p. 2405, doi. 10.1002/cbic.200990065
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- Article
Making Epothilones Fluoresce: Design, Synthesis, and Biological Characterization of a Fluorescent N12-Aza-Epothilone (Azathilone).
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- ChemBioChem, 2009, v. 10, n. 15, p. 2513, doi. 10.1002/cbic.200900376
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- Article
Differential Effects of Natural Product Microtubule Stabilizers on Microtubule Assembly: Single Agent and Combination Studies with Taxol, Epothilone B, and Discodermolide.
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- ChemBioChem, 2009, v. 10, n. 1, p. 166, doi. 10.1002/cbic.200800556
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Synthesis and Biological Evaluation of Aza-Epothilones.
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- ChemBioChem, 2000, v. 1, n. 1, p. 67, doi. 10.1002/1439-7633(20000703)1:1<67::AID-CBIC67>3.0.CO;2-I
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Structural insight into the stabilization of microtubules by taxanes.
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- eLife, 2023, p. 1, doi. 10.7554/eLife.84791
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- Article
Total Synthesis of Isoxeniolide A**.
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- Angewandte Chemie International Edition, 2024, v. 63, n. 9, p. 1, doi. 10.1002/anie.202315423
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- Article
Small molecule inhibitors provide insights into the relevance of LAT1 and LAT2 in materno‐foetal amino acid transport.
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- Journal of Cellular & Molecular Medicine, 2020, v. 24, n. 21, p. 12681, doi. 10.1111/jcmm.15840
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- Article
Rational Design of Membrane-Pore-Forming Peptides.
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- Small, 2017, v. 13, n. 40, p. n/a, doi. 10.1002/smll.201701316
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Peptides: Rational Design of Membrane-Pore-Forming Peptides (Small 40/2017).
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- Small, 2017, v. 13, n. 40, p. n/a, doi. 10.1002/smll.201770213
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Total Synthesis and Biological Evaluation of a C(10)/C(12)-Phenylene-Bridged Analog of Epothilone D.
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- Chemistry & Biodiversity, 2004, v. 1, n. 11, p. 1771, doi. 10.1002/cbdv.200490133
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Development of an ELISA for the quantification of mycolactone, the cytotoxic macrolide toxin of Mycobacterium ulcerans.
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- PLoS Neglected Tropical Diseases, 2020, v. 14, n. 6, p. 1, doi. 10.1371/journal.pntd.0008357
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Synthesis of the Multidrug Reversal Agent Ko143 and Its Parent Natural Product Fumitremorgin C.
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- Helvetica Chimica Acta, 2023, v. 106, n. 2, p. 1, doi. 10.1002/hlca.202200171
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Synthesis, Profiling, and Bioactive Conformation of trans‐Cyclopropyl Epothilones.
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- Helvetica Chimica Acta, 2019, v. 102, n. 5, p. N.PAG, doi. 10.1002/hlca.201900078
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A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04535-8
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- Article
Studies towards the Total Synthesis of Amycolamicin: A Chiral Auxiliary‐Based Diels‐Alder Approach towards the Decalin Core.
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- European Journal of Organic Chemistry, 2022, v. 2022, n. 30, p. 1, doi. 10.1002/ejoc.202200761
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- Article
Synthesis and Biological Evaluation of C(13)/C(13′)‐Bis(desmethyl)disorazole Z**.
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- Angewandte Chemie International Edition, 2023, v. 62, n. 5, p. 1, doi. 10.1002/anie.202212190
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An RCM‐Based Total Synthesis of the Antibiotic Disciformycin B.
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- Angewandte Chemie International Edition, 2020, v. 59, n. 40, p. 17393, doi. 10.1002/anie.202004589
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New Natural Noncannabinoid Ligands for Cannabinoid Type-2 (CB<sub>2</sub>) Receptors.
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- Journal of Receptors & Signal Transduction, 2006, v. 26, n. 5/6, p. 709, doi. 10.1080/10799890600942674
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Structure-Activity Relationship Studies on the Macrolide Exotoxin Mycolactone of Mycobacterium ulcerans.
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- PLoS Neglected Tropical Diseases, 2013, v. 7, n. 3, p. 1, doi. 10.1371/journal.pntd.0002143
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- Article
Structure-Activity Relationship Studies on the Macrolide Exotoxin Mycolactone of Mycobacterium ulcerans.
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- PLoS Neglected Tropical Diseases, 2013, v. 7, n. 3, p. 1, doi. 10.1371/journal.pntd.0002143
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- Article
The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2018, v. 37, n. 1, p. N.PAG, doi. 10.1186/s13046-018-0907-z
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The Evaluation of l‐Tryptophan Derivatives as Inhibitors of the l‐Type Amino Acid Transporter LAT1 (SLC7A5).
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- ChemMedChem, 2022, v. 17, n. 17, p. 1, doi. 10.1002/cmdc.202200308
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Synthesis and Biological Evaluation of Endocannabinoid Uptake Inhibitors Derived from WOBE437.
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- ChemMedChem, 2021, v. 16, n. 1, p. 145, doi. 10.1002/cmdc.202000153
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Front Cover: Total Synthesis of the Endocannabinoid Uptake Inhibitor Guineensine and SAR Studies (ChemMedChem 17/2019).
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- ChemMedChem, 2019, v. 14, n. 17, p. 1573, doi. 10.1002/cmdc.201900490
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Total Synthesis of the Endocannabinoid Uptake Inhibitor Guineensine and SAR Studies.
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- ChemMedChem, 2019, v. 14, n. 17, p. 1590, doi. 10.1002/cmdc.201900390
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The Impact of Cyclopropane Configuration on the Biological Activity of Cyclopropyl-Epothilones.
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- ChemMedChem, 2014, v. 9, n. 10, p. 2227, doi. 10.1002/cmdc.201402129
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Highly Potent Modulation of GABA<sub>A</sub> Receptors by Valerenic Acid Derivatives.
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- ChemMedChem, 2010, v. 5, n. 5, p. 678, doi. 10.1002/cmdc.201000062
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Cancer Chemotherapy: Basic Science to the Clinic. By Rachel Airley.
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- ChemMedChem, 2009, v. 4, n. 12, p. 2123, doi. 10.1002/cmdc.200900323
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Molecules that Changed the World. By K. C. Nicolaou and T. Montagnon.
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- ChemMedChem, 2008, v. 3, n. 4, p. 670, doi. 10.1002/cmdc.200800085
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Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 6, p. 1392, doi. 10.3390/ijms20061392
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Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 5, p. 1113, doi. 10.3390/ijms20051113
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Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell Migration.
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- International Journal of Molecular Sciences, 2017, v. 18, n. 5, p. 971, doi. 10.3390/ijms18050971
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Diversity through semisynthesis: the chemistry and biological activity of semisynthetic epothilone derivatives.
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- Molecular Diversity, 2011, v. 15, n. 2, p. 383, doi. 10.1007/s11030-010-9291-0
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Patupilone (epothilone B, EPO906) inhibits growth and metastasis of experimental prostate tumors in vivo.
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- Prostate, 2005, v. 65, n. 3, p. 231, doi. 10.1002/pros.20289
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- Article