Works by Alsfouk, Bshra A.

Results: 42

Isolation and In Silico Inhibitory Potential against SARS-CoV-2 RNA Polymerase of the Rare Kaempferol 3- O -(6″- O -acetyl)-Glucoside from Calligonum tetrapterum.

Published in:

Plants (2223-7747), 2022, v. 11, n. 15, p. 2072, doi. 10.3390/plants11152072

By:

Suleimen, Yerlan M.;
Jose, Rani A.;
Mamytbekova, Gulnur K.;
Suleimen, Raigul N.;
Ishmuratova, Margarita Y.;
Dehaen, Wim;
Alsfouk, Bshra A.;
Elkaeed, Eslam B.;
Eissa, Ibrahim H.;
Metwaly, Ahmed M.

Publication type:

Article

The Computational Preventive Potential of the Rare Flavonoid, Patuletin, Isolated from Tagetes patula , against SARS-CoV-2.

Published in:

Plants (2223-7747), 2022, v. 11, n. 14, p. N.PAG, doi. 10.3390/plants11141886

By:

Metwaly, Ahmed M.;
Elkaeed, Eslam B.;
Alsfouk, Bshra A.;
Saleh, Abdulrahman M.;
Mostafa, Ahmad E.;
Eissa, Ibrahim H.

Publication type:

Article

Tolerability of Antiseizure Medications in Individuals With Newly Diagnosed Epilepsy.

Published in:

JAMA Neurology, 2020, v. 77, n. 5, p. 574, doi. 10.1001/jamaneurol.2020.0032

By:

Alsfouk, Bshra Ali A.;
Brodie, Martin J.;
Walters, Matthew;
Kwan, Patrick;
Chen, Zhibin

Publication type:

Article

Neurodevelopmental outcomes in children exposed prenatally to levetiracetam.

Published in:

Therapeutic Advances in Drug Safety, 2022, v. 13, p. 1, doi. 10.1177/20420986221088419

By:

Alsfouk, Bshra A.

Publication type:

Article

Pharmacological outcomes in teenagers with newly diagnosed epilepsy: A 30‐year cohort study.

Published in:

Epilepsia (Series 4), 2019, v. 60, n. 6, p. 1083, doi. 10.1111/epi.15664

By:

Brodie, Martin J.;
Alsfouk, Bshra A.;
Alsfouk, Aisha A.;
Chen, Zhibin;
Kwan, Patrick

Publication type:

Article

Non-Adherence to Antiseizure Medications: Rate and Predictors in Saudi Arabia.

Published in:

Medicina (1010660X), 2024, v. 60, n. 10, p. 1649, doi. 10.3390/medicina60101649

By:

Alrukban, Noura A.;
Alotaibi, Sarah A.;
Alanizy, Layla N.;
Saleh, Ahmad;
Alsfouk, Bshra A.

Publication type:

Article

A novel thieno[2,3‐d]pyrimidine derivative inhibiting vascular endothelial growth factor receptor‐2: A story of computer‐aided drug discovery.

Published in:

Drug Development Research, 2023, v. 84, n. 6, p. 1247, doi. 10.1002/ddr.22083

By:

Sobh, Eman A.;
Dahab, Mohammed A.;
Elkaeed, Eslam B.;
Alsfouk, Bshra A.;
Ibrahim, Ibrahim M.;
Metwaly, Ahmed M.;
Eissa, Ibrahim H.

Publication type:

Article

Discovery of New VEGFR-2 Inhibitors: Design, Synthesis, Anti-Proliferative Evaluation, Docking, and MD Simulation Studies.

Published in:

Molecules, 2022, v. 27, n. 19, p. 6203, doi. 10.3390/molecules27196203

By:

Elkaeed, Eslam B.;
Yousef, Reda G.;
Khalifa, Mohamed M.;
Ibrahim, Albaraa;
Mehany, Ahmed B. M.;
Gobaara, Ibraheem M. M.;
Alsfouk, Bshra A.;
Eldehna, Wagdy M.;
Metwaly, Ahmed M.;
Eissa, Ibrahim H.;
El-Zahabi, Mohamed Ayman

Publication type:

Article

Design, Synthesis, Docking, DFT, MD Simulation Studies of a New Nicotinamide-Based Derivative: In Vitro Anticancer and VEGFR-2 Inhibitory Effects.

Published in:

Molecules, 2022, v. 27, n. 14, p. N.PAG, doi. 10.3390/molecules27144606

By:

Elkaeed, Eslam B.;
Yousef, Reda G.;
Elkady, Hazem;
Gobaara, Ibraheem M. M.;
Alsfouk, Bshra A.;
Husein, Dalal Z.;
Ibrahim, Ibrahim M.;
Metwaly, Ahmed M.;
Eissa, Ibrahim H.

Publication type:

Article

Design, Synthesis, In Silico and In Vitro Studies of New Immunomodulatory Anticancer Nicotinamide Derivatives Targeting VEGFR-2.

Published in:

Molecules, 2022, v. 27, n. 13, p. 4079, doi. 10.3390/molecules27134079

By:

Yousef, Reda G.;
Eldehna, Wagdy M.;
Elwan, Alaa;
Abdelaziz, Abdelaziz S.;
Mehany, Ahmed B. M.;
Gobaara, Ibraheem M. M.;
Alsfouk, Bshra A.;
Elkaeed, Eslam B.;
Metwaly, Ahmed M.;
Eissa, Ibrahim H.

Publication type:

Article

Ligand and Structure-Based In Silico Determination of the Most Promising SARS-CoV-2 nsp16-nsp10 2′- o -Methyltransferase Complex Inhibitors among 3009 FDA Approved Drugs.

Published in:

Molecules, 2022, v. 27, n. 7, p. 2287, doi. 10.3390/molecules27072287

By:

Eissa, Ibrahim H.;
Alesawy, Mohamed S.;
Saleh, Abdulrahman M.;
Elkaeed, Eslam B.;
Alsfouk, Bshra A.;
El-Attar, Abdul-Aziz M. M.;
Metwaly, Ahmed M.

Publication type:

Article

Jusanin, a New Flavonoid from Artemisia commutata with an In Silico Inhibitory Potential against the SARS-CoV-2 Main Protease.

Published in:

Molecules, 2022, v. 27, n. 5, p. 1636, doi. 10.3390/molecules27051636

By:

Suleimen, Yerlan M.;
Jose, Rani A.;
Suleimen, Raigul N.;
Arenz, Christoph;
Ishmuratova, Margarita Y.;
Toppet, Suzanne;
Dehaen, Wim;
Alsfouk, Bshra A.;
Elkaeed, Eslam B.;
Eissa, Ibrahim H.;
Metwaly, Ahmed M.

Publication type:

Article

Should substitution monotherapy or combination therapy be used after failure of the first antiseizure medication? Observations from a 30‐year cohort study.

Published in:

Epilepsia (Series 4), 2023, v. 64, n. 5, p. 1248, doi. 10.1111/epi.17573

By:

Hakeem, Haris;
Alsfouk, Bshra Ali A.;
Kwan, Patrick;
Brodie, Martin J.;
Chen, Zhibin

Publication type:

Article

Characteristics and treatment outcomes of newly diagnosed epilepsy in older people: A 30‐year longitudinal cohort study.

Published in:

Epilepsia (Series 4), 2020, v. 61, n. 12, p. 2720, doi. 10.1111/epi.16721

By:

Alsfouk, Bshra Ali A.;
Hakeem, Haris;
Chen, Zhibin;
Walters, Matthew;
Brodie, Martin J.;
Kwan, Patrick

Publication type:

Article

Chemical composition, antimicrobial, and antioxidant properties of essential oils from Artemisia herba-alba asso. and Artemisia huguetii caball. from Morocco: in vitro and in silico evaluation.

Published in:

Frontiers in Chemistry, 2024, p. 1, doi. 10.3389/fchem.2024.1456684

By:

El Ouardi, Mohamed;
Drioiche, Aziz;
El Makhoukhi, Fadoua;
Mabrouki, Jamal;
Hakmi, Mohammed;
Al kamaly, Omkulthom;
A. Alsfouk, Bshra;
Eddamsyry, Brahim;
Khamar, Hamid;
Zair, Touriya;
Alaoui El Belghiti, Mohammed

Publication type:

Article

Discovery of new quinoline and isatine derivatives as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative, docking and MD simulation studies.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 21, p. 11535, doi. 10.1080/07391102.2022.2164356

By:

Taghour, Mohammed S.;
Elkady, Hazem;
Eldehna, Wagdy M.;
El-Deeb, Nehal;
Kenawy, Ahmed M.;
Abd El-Wahab, Abeer E;
Elkaeed, Eslam B.;
Alsfouk, Bshra A.;
Metwaly, Ahmed M.;
Eissa, Ibrahim H.

Publication type:

Article

In silico, in vitro VEGFR-2 inhibition, and anticancer activity of a 3-(hydrazonomethyl)naphthalene-2-ol derivative.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 16, p. 7986, doi. 10.1080/07391102.2022.2127907

By:

Elkaeed, Eslam B.;
Yousef, Reda G.;
Elkady, Hazem;
Mehany, Ahmed B. M.;
Alsfouk, Bshra A.;
Husein, Dalal Z.;
Ibrahim, Ibrahim M.;
Metwaly, Ahmed M.;
Eissa, Ibrahim H.

Publication type:

Article

New thieno[2,3‐d]pyrimidine derivatives as EGFR<sup>WT</sup> and EGFR<sup>T790M</sup> inhibitors: Design, synthesis, antiproliferative activities, docking studies, ADMET, toxicity, MD simulation studies.

Published in:

Journal of Heterocyclic Chemistry, 2024, v. 61, n. 2, p. 285, doi. 10.1002/jhet.4757

By:

Sobh, Eman A.;
Dahab, Mohammed A.;
Elkaeed, Eslam B.;
Alsfouk, Bshra A.;
Ibrahim, Ibrahim M.;
Metwaly, Ahmed M.;
Eissa, Ibrahim H.

Publication type:

Article

Isolation and in silico investigation of cannflavins from Cannabis sativa leaves as potential anti-SARS-CoV-2 agents targeting the Papain-Like Protease.

Published in:

Natural Product Research, 2025, v. 39, n. 5, p. 1081, doi. 10.1080/14786419.2023.2294111

By:

Wanas, Amira S.;
Radwan, Mohamed M.;
Marzouk, Adel A.;
Elkaeed, Eslam B.;
Alsfouk, Bshra A.;
Mostafa, Ahmad E.;
Eissa, Ibrahim H.;
Metwaly, Ahmed M.;
ElSohly, Mahmoud A.

Publication type:

Article

Computer-aided drug discovery of natural antiviral metabolites as potential SARS-CoV-2 helicase inhibitors.

Published in:

Journal of Chemical Research, 2024, v. 48, n. 1, p. 1, doi. 10.1177/17475198231221253

By:

Elkaeed, Eslam B;
Eissa, Ibrahim H;
Saleh, Abdulrahman M;
Alsfouk, Bshra A;
Metwaly, Ahmed M

Publication type:

Article

Multi-Phase In Silico Discovery of Potential SARS-CoV-2 RNA-Dependent RNA Polymerase Inhibitors among 3009 Clinical and FDA-Approved Related Drugs.

Published in:

Processes, 2022, v. 10, n. 3, p. 530, doi. 10.3390/pr10030530

By:

Elkaeed, Eslam B.;
Elkady, Hazem;
Belal, Amany;
Alsfouk, Bshra A.;
Ibrahim, Tuqa H.;
Abdelmoaty, Mohamed;
Arafa, Reem K.;
Metwaly, Ahmed M.;
Eissa, Ibrahim H.

Publication type:

Article

Design, synthesis, anti-proliferative evaluation, docking, and MD simulations studies of new thiazolidine-2,4-diones targeting VEGFR-2 and apoptosis pathway.

Published in:

PLoS ONE, 2022, v. 17, n. 9, p. 1, doi. 10.1371/journal.pone.0272362

By:

Taghour, Mohammed S.;
Elkady, Hazem;
Eldehna, Wagdy M.;
El-Deeb, Nehal;
Kenawy, Ahmed M.;
Elkaeed, Eslam B.;
Alsfouk, Bshra A.;
Alesawy, Mohamed S.;
Husein, Dalal Z.;
Metwaly, Ahmed M.;
Eissa, Ibrahim H.

Publication type:

Article

The Discovery of Potential SARS-CoV-2 Natural Inhibitors among 4924 African Metabolites Targeting the Papain-like Protease: A Multi-Phase In Silico Approach.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 11, p. 1122, doi. 10.3390/metabo12111122

By:

Elkaeed, Eslam B.;
Khalifa, Mohamed M.;
Alsfouk, Bshra A.;
Alsfouk, Aisha A.;
El-Attar, Abdul-Aziz M. M.;
Eissa, Ibrahim H.;
Metwaly, Ahmed M.

Publication type:

Article

A New Anticancer Semisynthetic Theobromine Derivative Targeting EGFR Protein: CADDD Study.

Published in:

Life (2075-1729), 2023, v. 13, n. 1, p. 191, doi. 10.3390/life13010191

By:

Eissa, Ibrahim H.;
Yousef, Reda G.;
Elkady, Hazem;
Alsfouk, Aisha A.;
Alsfouk, Bshra A.;
Husein, Dalal Z.;
Ibrahim, Ibrahim M.;
Elkaeed, Eslam B.;
Metwaly, Ahmed M.

Publication type:

Article

Design and In Silico and In Vitro Evaluations of a Novel Nicotinamide Derivative as a VEGFR-2 Inhibitor.

Published in:

Journal of Chemistry, 2024, v. 2024, p. 1, doi. 10.1155/2024/2176512

By:

Eissa, Ibrahim H.;
Bkrah, Muhammad Abd ElGayed;
Yousef, Reda G.;
Elkady, Hazem;
Elkaeed, Eslam B.;
Alsfouk, Bshra A.;
Ibrahim, Ibrahim M.;
Metwaly, Ahmed M.;
Husein, Dalal Z.

Publication type:

Article

Preparation and Characterization of Patuletin-Loaded Chitosan Nanoparticles with Improved Selectivity and Safety Profiles for Anticancer Applications.

Published in:

Journal of Chemistry, 2023, p. 1, doi. 10.1155/2023/6684015

By:

Metwaly, Ahmed M.;
Abdel-Raoof, Ahmed M.;
Alattar, Abdulaziz M.;
El-Zomrawy, Adham A.;
Ashmawy, Ashraf M.;
Metwally, Metwally G.;
Abu-Saied, Mohamed A.;
Lotfy, Asmaa M.;
Alsfouk, Bshra A.;
Elkaeed, Eslam B.;
Eissa, Ibrahim H.

Publication type:

Article

Development and Validation of a New Adherence Scale for Antiseizure Medications [ASASM].

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 24, p. 7844, doi. 10.3390/jcm13247844

By:

Alotaibi, Sarah A.;
Alrukban, Noura A.;
Alanizy, Layla N.;
Saleh, Ahmad;
Alsfouk, Bshra A.

Publication type:

Article

Comparative Efficacy of Inhaled and Intravenous Corticosteroids in Managing COVID-19-Related Acute Respiratory Distress Syndrome.

Published in:

Pharmaceutics, 2024, v. 16, n. 7, p. 952, doi. 10.3390/pharmaceutics16070952

By:

Abdelkader, Ahmed A.;
Alsfouk, Bshra A.;
Saleh, Asmaa;
Abdelrahim, Mohamed E. A.;
Saeed, Haitham

Publication type:

Article

Pharmacogenetics as a Future Tool to Risk-Stratify Breast Cancer Patients According to Chemotoxicity Potential from the Doxorubicin Hydrochloride and Cyclophosphamide (AC) Regimen.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 4, p. 539, doi. 10.3390/ph18040539

By:

Abdelfattah, Esraa K.;
Hosny, Sanaa M.;
Kassem, Amira B.;
Moustafa, Hebatallah Ahmed Mohamed;
Tawfeik, Amany M.;
Abdelhafez, Marwa N.;
El-Sheshtawy, Wael;
Alsfouk, Bshra A.;
Saleh, Asmaa;
Salem, Hoda A.

Publication type:

Article

Evaluating the Use of Inhaled Budesonide and Ipratropium Bromide Combination in Patients at High Risk of Acute Respiratory Distress Syndrome Development: A Randomized Controlled Trial.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 3, p. 412, doi. 10.3390/ph18030412

By:

Moustafa, Hebatallah Ahmed Mohamed;
Elbery, Faten H.;
Al Meslamani, Ahmad Z.;
Okda, Sherouk M.;
Alsfouk, Bshra A.;
Kassem, Amira B.

Publication type:

Article

New Imadazopyrazines with CDK9 Inhibitory Activity as Anticancer and Antiviral: Synthesis, In Silico, and In Vitro Evaluation Approaches.

Published in:

Pharmaceuticals (14248247), 2023, v. 16, n. 7, p. 1018, doi. 10.3390/ph16071018

By:

Alsfouk, Aisha A.;
Alshibl, Hanan M.;
Altwaijry, Najla A.;
Alanazi, Ashwag;
AlKamaly, Omkulthom;
Sultan, Ahlam;
Alsfouk, Bshra A.

Publication type:

Article

Synthesis and Biological Evaluation of Imadazo[1,2- a ]pyrazines as Anticancer and Antiviral Agents through Inhibition of CDK9 and Human Coronavirus.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 7, p. N.PAG, doi. 10.3390/ph15070859

By:

Alsfouk, Aisha A.;
Alshibl, Hanan M.;
Alsfouk, Bshra A.;
Altwaijry, Najla A.;
Al-Abdullah, Ebtehal S.

Publication type:

Article

Computer-Assisted Drug Discovery of Potential African Anti-SARS-CoV-2 Natural Products Targeting the Helicase Protein.

Published in:

Natural Product Communications, 2024, v. 19, n. 4, p. 1, doi. 10.1177/1934578X241246738

By:

Metwaly, Ahmed M.;
Alesawy, Mohamed S.;
Alsfouk, Bshra A.;
Ibrahim, Ibrahim M.;
Elkaeed, Eslam B.;
Eissa, Ibrahim H.

Publication type:

Article

Investigation of 3-Phenylcoumarin Derivatives as Potential Multi-target Inhibitors for Human Cholinesterases and Monoamine oxidases: A Computational Approach.

Published in:

Applied Biochemistry & Biotechnology, 2024, v. 196, n. 11, p. 8389, doi. 10.1007/s12010-024-04996-2

By:

Fayyaz, Ammara;
Ejaz, Syeda Abida;
Alsfouk, Bshra A.;
Ejaz, Syeda Rabia

Publication type:

Article

In Silico Prospects and Therapeutic Applications of Ouabagenin and Hydroxylated Corticosteroid Analogues in the Treatment of Lung Cancer.

Published in:

Applied Biochemistry & Biotechnology, 2022, v. 194, n. 12, p. 6106, doi. 10.1007/s12010-022-04083-4

By:

Ejaz, Syeda Abida;
Aziz, Mubashir;
Birmani, Pervez Rashid;
Alsfouk, Bshra A.;
Alharbi, F. F.;
Bilal, Muhammad Sajjad;
Hassan, Sidra;
Umar, Haruna Isiyaku;
Elhadi, Muawya

Publication type:

Article

New quinoline and isatin derivatives as apoptotic VEGFR-2 inhibitors: design, synthesis, anti-proliferative activity, docking, ADMET, toxicity, and MD simulation studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 2191, doi. 10.1080/14756366.2022.2110869

By:

Elkaeed, Eslam B.;
Taghour, Mohammed S.;
Mahdy, Hazem A.;
Eldehna, Wagdy M.;
El-Deeb, Nehal M.;
Kenawy, Ahmed M.;
Alsfouk, Bshra A.;
Dahab, Mohammed A.;
Metwaly, Ahmed M.;
Eissa, Ibrahim H.;
El-Zahabi, Mohamed A.

Publication type:

Article

Anti-cancer and immunomodulatory evaluation of new nicotinamide derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: in vitro and in silico studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 2206, doi. 10.1080/14756366.2022.2110868

By:

Yousef, Reda G.;
Elwan, Alaa;
Gobaara, Ibraheem M. M.;
Mehany, Ahmed B. M.;
Eldehna, Wagdy M.;
El-Metwally, Souad A.;
Alsfouk, Bshra A.;
Elkaeed, Eslam B.;
Metwaly, Ahmed M.;
Eissa, Ibrahim H.

Publication type:

Article

Experimental and computational analyses of the anti-alzheimer and antidiabetic effects of flavonoid-rich extract of avocado seeds (Persea americana Mill.).

Published in:

Nutrire, 2025, v. 50, n. 1, p. 1, doi. 10.1186/s41110-025-00335-5

By:

Ojo, Oluwafemi Adeleke;
Maduakolam-Aniobi, Tobiloba Christiana;
Gyebi, Gideon Ampoma;
Soyinka, Tenifayo Oluwatamilore;
Ejiogu, Obianuju Favour;
Ojo, Adebola Busola;
Alruwaili, Mubarak;
Ali, Naif H.;
Alnaaim, Saud A.;
Alsfouk, Bshra A.;
Batiha, Gaber El-Saber

Publication type:

Article

Computer-assisted drug discovery of potential natural inhibitors of the SARS-CoV-2 RNA-dependent RNA polymerase through a multi-phase in silico approach.

Published in:

Antiviral Therapy, 2023, v. 28, n. 5, p. 1, doi. 10.1177/13596535231199838

By:

Elkaeed, Eslam B.;
Alsfouk, Bshra A.;
Ibrahim, Tuqa H.;
Arafa, Reem K.;
Elkady, Hazem;
Ibrahim, Ibrahim M.;
Eissa, Ibrahim H.;
Metwaly, Ahmed M.

Publication type:

Article

Repurposing of Strychnine as the Potential Inhibitors of Aldo–keto Reductase Family 1 Members B1 and B10: Computational Modeling and Pharmacokinetic Analysis.

Published in:

Protein Journal, 2024, v. 43, n. 2, p. 207, doi. 10.1007/s10930-023-10163-z

By:

Sarfraz, Muhammad;
Aziz, Mubashir;
Afzal, Saira;
Channar, Pervaiz Ali;
Alsfouk, Bshra A.;
Kandhro, Ghulam Abbas;
Hassan, Sidra;
Sultan, Ahlam;
Hamad, Asad;
Arafat, Mosab;
Qaiser, Muhammad Naeem;
Ahmed, Aftab;
Siddique, Farhan;
Ejaz, Syeda Abida

Publication type:

Article

Novel Thiazolidine‐2,4‐Dione Derivatives as Potential VEGFR‐2 Inhibitors: Synthesis, Biological Testing, and in Silico Studies.

Published in:

ChemistrySelect, 2024, v. 9, n. 11, p. 1, doi. 10.1002/slct.202303095

By:

Eissa, Ibrahim;
Elkady, Hazem;
Taghour, Mohammed S.;
Elwan, Alaa;
Dahab, Mohammed A.;
Hagras, Mohamed;
Elkaeed, Eslam B.;
Alsfouk, Bshra A.;
Ibrahim, Ibrahim M.;
Husein, Dalal Z.;
Hafez, Elsayed E.;
Mansour, Hanem M.;
Metwaly, Ahmed;
Mahdy, Hazem A.

Publication type:

Article

Distance Education During COVID-19 Pandemic: A College of Pharmacy Experience.

Published in:

Risk Management & Healthcare Policy, 2021, v. 14, p. 2099, doi. 10.2147/RMHP.S308998

By:

Altwaijry, Najla;
Ibrahim, Alnada;
Binsuwaidan, Reem;
Alnajjar, Lina I;
Alsfouk, Bshra A;
Almutairi, Raghdah

Publication type:

Article