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Stereochemically-aware bioactivity descriptors for uncharacterized chemical compounds.
- Published in:
- Journal of Cheminformatics, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13321-024-00867-4
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- Publication type:
- Article
Global analysis of suppressor mutations that rescue human genetic defects.
- Published in:
- Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-023-01232-0
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- Publication type:
- Article
BQsupports: systematic assessment of the support and novelty of new biomedical associations.
- Published in:
- Bioinformatics, 2023, v. 39, n. 9, p. 1, doi. 10.1093/bioinformatics/btad581
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- Publication type:
- Article
Democratizing knowledge representation with BioCypher.
- Published in:
- 2023
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- Publication type:
- Letter
Integrating and formatting biomedical data as pre-calculated knowledge graph embeddings in the Bioteque.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33026-0
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- Publication type:
- Article
Identification and drug-induced reversion of molecular signatures of Alzheimer's disease onset and progression in App<sup>NL-G-F</sup>, App<sup>NL-F</sup>, and 3xTg-AD mouse models.
- Published in:
- Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00983-y
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- Publication type:
- Article
Association of Transcriptomic Signatures of Inflammatory Response with Viral Control after Dendritic Cell-Based Therapeutic Vaccination in HIV-1 Infected Individuals.
- Published in:
- Vaccines, 2021, v. 9, n. 7, p. 799, doi. 10.3390/vaccines9070799
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- Publication type:
- Article
Bioactivity descriptors for uncharacterized chemical compounds.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24150-4
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- Publication type:
- Article
Natural variants suppress mutations in hundreds of essential genes.
- Published in:
- Molecular Systems Biology, 2021, v. 17, n. 5, p. 1, doi. 10.15252/msb.202010138
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- Publication type:
- Article
Analysing the yeast complexome—the Complex Portal rising to the challenge.
- Published in:
- Nucleic Acids Research, 2021, v. 49, n. 6, p. 3156, doi. 10.1093/nar/gkab077
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- Publication type:
- Article
Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns.
- Published in:
- Genome Medicine, 2020, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13073-020-00774-x
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- Publication type:
- Article
Systematic analysis of bypass suppression of essential genes.
- Published in:
- Molecular Systems Biology, 2020, v. 16, n. 9, p. 1, doi. 10.15252/msb.20209828
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- Publication type:
- Article
Extending the small-molecule similarity principle to all levels of biology with the Chemical Checker.
- Published in:
- Nature Biotechnology, 2020, v. 38, n. 9, p. 1087, doi. 10.1038/s41587-020-0502-7
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- Publication type:
- Article
Publisher Correction: Extending the small-molecule similarity principle to all levels of biology with the Chemical Checker.
- Published in:
- 2020
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- Publication type:
- Correction Notice
Systematic genetics and single‐cell imaging reveal widespread morphological pleiotropy and cell‐to‐cell variability.
- Published in:
- Molecular Systems Biology, 2020, v. 16, n. 2, p. 1, doi. 10.15252/msb.20199243
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- Publication type:
- Article
Virological Outcome Measures During Analytical Treatment Interruptions in Chronic HIV-1-Infected Patients.
- Published in:
- Open Forum Infectious Diseases, 2019, v. 6, n. 12, p. N.PAG, doi. 10.1093/ofid/ofz485
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- Publication type:
- Article
DYRK1A Overexpression Alters Cognition and Neural-Related Proteomic Pathways in the Hippocampus That Are Rescued by Green Tea Extract and/or Environmental Enrichment.
- Published in:
- Frontiers in Molecular Neuroscience, 2019, v. 12, p. N.PAG, doi. 10.3389/fnmol.2019.00272
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- Publication type:
- Article
Formatting biological big data for modern machine learning in drug discovery.
- Published in:
- WIREs: Computational Molecular Science, 2019, v. 9, n. 6, p. N.PAG, doi. 10.1002/wcms.1408
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- Publication type:
- Article
Cover Image, Volume 9, Issue 6.
- Published in:
- WIREs: Computational Molecular Science, 2019, v. 9, n. 6, p. N.PAG, doi. 10.1002/wcms.1451
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- Publication type:
- Article
Truncating variant burden in high-functioning autism and pleiotropic effects of LRP1 across psychiatric phenotypes.
- Published in:
- Journal of Psychiatry & Neuroscience, 2019, v. 44, n. 5, p. 350, doi. 10.1503/jpn.180184
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- Publication type:
- Article
In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases.
- Published in:
- Frontiers in Physiology, 2019, p. N.PAG, doi. 10.3389/fphys.2019.00314
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- Publication type:
- Article
Encircling the regions of the pharmacogenomic landscape that determine drug response.
- Published in:
- Genome Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13073-019-0626-x
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- Publication type:
- Article
Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06353-4
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- Publication type:
- Article
Exploring the OncoGenomic Landscape of cancer.
- Published in:
- Genome Medicine, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13073-018-0571-0
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- Publication type:
- Article
Systems analysis of intracellular pH vulnerabilities for cancer therapy.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05261-x
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- Publication type:
- Article
A framework for exhaustively mapping functional missense variants.
- Published in:
- Molecular Systems Biology, 2017, v. 13, n. 12, p. 1, doi. 10.15252/msb.20177908
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- Publication type:
- Article
A PanorOmic view of personal cancer genomes.
- Published in:
- Nucleic Acids Research, 2017, v. 45, n. W1, p. W195, doi. 10.1093/nar/gkx311
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- Publication type:
- Article
Detecting similar binding pockets to enable systems polypharmacology.
- Published in:
- PLoS Computational Biology, 2017, v. 13, n. 6, p. 1, doi. 10.1371/journal.pcbi.1005522
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- Publication type:
- Article
Novel Neuroprotective Multicomponent Therapy for Amyotrophic Lateral Sclerosis Designed by Networked Systems.
- Published in:
- PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0147626
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- Publication type:
- Article
Using neighborhood cohesiveness to infer interactions between protein domains.
- Published in:
- Bioinformatics, 2015, v. 31, n. 15, p. 2545, doi. 10.1093/bioinformatics/btv188
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- Publication type:
- Article
Drug sensitivity in cancer cell lines is not tissue-specific.
- Published in:
- Molecular Cancer, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12943-015-0312-6
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- Publication type:
- Article
dSysMap: exploring the edgetic role of disease mutations.
- Published in:
- Nature Methods, 2015, v. 12, n. 3, p. 167, doi. 10.1038/nmeth.3289
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- Publication type:
- Article
IntSide: a web server for the chemical and biological examination of drug side effects.
- Published in:
- Bioinformatics, 2015, v. 31, n. 4, p. 612, doi. 10.1093/bioinformatics/btu688
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- Publication type:
- Article
Breast Cancer Genes PSMC3IP and EPSTI1 Play a Role in Apoptosis Regulation.
- Published in:
- PLoS ONE, 2015, v. 10, n. 1, p. 1, doi. 10.1371/journal.pone.0115352
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- Publication type:
- Article
The EHEC-host interactome reveals novel targets for the translocated intimin receptor.
- Published in:
- Scientific Reports, 2014, p. 1, doi. 10.1038/srep07531
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- Publication type:
- Article
A chemo-centric view of human health and disease.
- Published in:
- Nature Communications, 2014, v. 5, n. 12, p. 5676, doi. 10.1038/ncomms6676
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- Publication type:
- Article
The binary protein-protein interaction landscape of Escherichia coli.
- Published in:
- Nature Biotechnology, 2014, v. 32, n. 3, p. 285, doi. 10.1038/nbt.2831
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- Publication type:
- Article
3did: a catalog of domain-based interactions of known three-dimensional structure.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. D1, p. D374, doi. 10.1093/nar/gkt887
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- Publication type:
- Article
Functional and Structural Analysis of C-Terminal BRCA1 Missense Variants.
- Published in:
- PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061302
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- Publication type:
- Article
The Proton-Pump Inhibitor Lansoprazole Enhances Amyloid Beta Production.
- Published in:
- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058837
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- Publication type:
- Article
Interactome3D: adding structural details to protein networks.
- Published in:
- Nature Methods, 2013, v. 10, n. 1, p. 47, doi. 10.1038/nmeth.2289
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- Publication type:
- Article
Systems biology technology identifies presenilin-1–interacting proteins and drug targets that are novel to the Alzheimer's disease field
- Published in:
- 2012
- By:
- Publication type:
- Abstract
NetAligner—a network alignment server to compare complexes, pathways and whole interactomes.
- Published in:
- Nucleic Acids Research, 2012, v. 40, p. W157, doi. 10.1093/nar/gks446
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- Publication type:
- Article
Towards Alzheimer's root cause: ECSIT as an integrating hub between oxidative stress, inflammation and mitochondrial dysfunction.
- Published in:
- BioEssays, 2012, v. 34, n. 7, p. 532, doi. 10.1002/bies.201100193
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- Publication type:
- Article
From protein interaction networks to novel therapeutic strategies.
- Published in:
- IUBMB Life, 2012, v. 64, n. 6, p. 529, doi. 10.1002/iub.1040
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- Publication type:
- Article
A Novel Framework for the Comparative Analysis of Biological Networks.
- Published in:
- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031220
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- Publication type:
- Article
On the analysis of protein-protein interactions via knowledge-based potentials for the prediction of protein-protein docking.
- Published in:
- Protein Science: A Publication of the Protein Society, 2011, v. 20, n. 3, p. 529, doi. 10.1002/pro.585
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- Publication type:
- Article
3did: identification and classification of domain-based interactions of known three-dimensional structure.
- Published in:
- Nucleic Acids Research, 2011, v. 39, n. suppl_1, p. D718, doi. 10.1093/nar/gkq962
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- Publication type:
- Article
Uncovering new substrates for Aurora A kinase.
- Published in:
- EMBO Reports, 2010, v. 11, n. 12, p. 977, doi. 10.1038/embor.2010.171
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- Publication type:
- Article
Novel Peptide-Mediated Interactions Derived from High-Resolution 3-Dimensional Structures.
- Published in:
- PLoS Computational Biology, 2010, v. 6, n. 5, p. 1, doi. 10.1371/journal.pcbi.1000789
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- Publication type:
- Article