Works matching AU Almeida, Luís Pereira de
Results: 64
Caffeine alleviates progressive motor deficits in a transgenic mouse model of spinocerebellar ataxia.
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- 2017
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- Publication type:
- journal article
Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells.
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- 2020
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- journal article
Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease.
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- 2015
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- journal article
Isolation of Extracellular Vesicles from Human Follicular Fluid: Size-Exclusion Chromatography versus Ultracentrifugation.
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- Biomolecules (2218-273X), 2023, v. 13, n. 2, p. 278, doi. 10.3390/biom13020278
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- Article
Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy.
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- Cell Death & Disease, 2021, v. 12, n. 12, p. 1, doi. 10.1038/s41419-021-04404-1
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- Article
Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?
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- Cell Death & Disease, 2021, v. 12, n. 6, p. 1, doi. 10.1038/s41419-021-03873-8
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- Article
Motor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive Review.
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- Frontiers in Neuroscience, 2016, v. 10, p. 1, doi. 10.3389/fnins.2016.00572
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- Article
Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models.
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- Journal of Cell Biology, 2016, v. 212, n. 4, p. 465, doi. 10.1083/jcb.201506025
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- Article
Successes and Hurdles in Stem Cells Application and Production for Brain Transplantation.
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- Frontiers in Neuroscience, 2019, v. 13, p. 1, doi. 10.3389/fnins.2019.01194
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- Article
Trehalose alleviates the phenotype of Machado-Joseph disease mouse models.
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- 2020
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- Publication type:
- journal article
Graft-derived neurons and bystander effects are maintained for six months after human iPSC-derived NESC transplantation in mice's cerebella.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-53542-x
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- Article
MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma.
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- Human Molecular Genetics, 2013, v. 22, n. 5, p. 904, doi. 10.1093/hmg/dds496
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- Article
Silencing ataxin-3 mitigates degeneration in a rat model of Machado–Joseph disease: no role for wild-type ataxin-3?
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- Human Molecular Genetics, 2010, v. 19, n. 12, p. 2380, doi. 10.1093/hmg/ddq111
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- Article
Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease.
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- Human Molecular Genetics, 2008, v. 17, n. 14, p. 2071, doi. 10.1093/hmg/ddn106
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- Article
Mesenchymal Stromal Cells' Therapy for Polyglutamine Disorders: Where Do We Stand and Where Should We Go?
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- Frontiers in Cellular Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fncel.2020.584277
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- Article
Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway.
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- Nature Communications, 2016, v. 7, n. 5, p. 11445, doi. 10.1038/ncomms11445
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- Article
Caffeine and adenosine A(2A) receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado-Joseph disease.
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- 2013
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- Publication type:
- journal article
Viral-based animal models in polyglutamine disorders.
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- Brain: A Journal of Neurology, 2024, v. 147, n. 4, p. 1166, doi. 10.1093/brain/awae012
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- Article
stress granule protein G3BP1 alleviates spinocerebellar ataxia-associated deficits.
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- Brain: A Journal of Neurology, 2023, v. 146, n. 6, p. 2346, doi. 10.1093/brain/awac473
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- Article
IGF-1 Intranasal Administration Rescues Huntington's Disease Phenotypes in YAC128 Mice.
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- Molecular Neurobiology, 2014, v. 49, n. 3, p. 1126, doi. 10.1007/s12035-013-8585-5
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- Article
Characterization of common and rare human papillomaviruses in Portuguese women by the polymerase chain reaction, restriction fragment length polymorphism and sequencing.
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- Journal of Medical Virology, 2010, v. 82, n. 6, p. 1024, doi. 10.1002/jmv.21756
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- Article
The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samples.
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- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. N.PAG, doi. 10.1186/s40478-020-00955-0
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- Article
In Vitro Evaluation of Biphasic Calcium Phosphate Scaffolds Derived from Cuttlefish Bone Coated with Poly(ester urea) for Bone Tissue Regeneration.
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- Polymers (20734360), 2023, v. 15, n. 10, p. 2256, doi. 10.3390/polym15102256
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- Article
Mannose and Lactobionic Acid in Nasal Vaccination: Enhancing Antigen Delivery via C-Type Lectin Receptors.
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- Pharmaceutics, 2024, v. 16, n. 10, p. 1308, doi. 10.3390/pharmaceutics16101308
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- Article
miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production.
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- Immunology, 2012, v. 135, n. 1, p. 73, doi. 10.1111/j.1365-2567.2011.03514.x
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- Article
Stage‐Dependent Biomarker Changes in Spinocerebellar Ataxia Type 3.
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- Annals of Neurology, 2024, v. 95, n. 2, p. 400, doi. 10.1002/ana.26824
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- Article
Modeling Lysosomal Storage Disorders in an Innovative Way: Establishment and Characterization of Stem Cell Lines from Human Exfoliated Deciduous Teeth of Mucopolysaccharidosis Type II Patients.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 6, p. 3546, doi. 10.3390/ijms25063546
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- Article
Phosphoproteome Microarray Analysis of Extracellular Particles as a Tool to Explore Novel Biomarker Candidates for Alzheimer's Disease.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 3, p. 1584, doi. 10.3390/ijms25031584
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- Article
A Novel Genetic Variant in MBD5 Associated with Severe Epilepsy and Intellectual Disability: Potential Implications on Neural Primary Cilia.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 16, p. 12603, doi. 10.3390/ijms241612603
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- Article
SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 12, p. 6790, doi. 10.3390/ijms23126790
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- Article
Extracellular Vesicles Physiological Role and the Particular Case of Disease-Spreading Mechanisms in Polyglutamine Diseases.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 22, p. 12288, doi. 10.3390/ijms222212288
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- Article
Living Proof of Activity of Extracellular Vesicles in the Central Nervous System.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 14, p. 7294, doi. 10.3390/ijms22147294
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- Article
Fourier Transform Infrared Spectroscopy Analysis as a Tool to Address Aβ Impact on Extracellular Vesicles.
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- Molecules, 2025, v. 30, n. 2, p. 258, doi. 10.3390/molecules30020258
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- Article
Ghrelin delays premature aging in Hutchinson‐Gilford progeria syndrome.
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- Aging Cell, 2023, v. 22, n. 12, p. 1, doi. 10.1111/acel.13983
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- Article
Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph Disease.
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- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01329-4
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- Article
The autophagy‐enhancing drug carbamazepine improves neuropathology and motor impairment in mouse models of Machado–Joseph disease.
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- Neuropathology & Applied Neurobiology, 2022, v. 48, n. 1, p. 1, doi. 10.1111/nan.12763
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- Article
Identification of the calpain‐generated toxic fragment of ataxin‐3 protein provides new avenues for therapy of Machado–Joseph disease| Spinocerebellar ataxia type 3.
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- Neuropathology & Applied Neurobiology, 2022, v. 48, n. 1, p. 1, doi. 10.1111/nan.12748
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- Article
Highly Specific Blood-Brain Barrier Transmigrating Single-Domain Antibodies Selected by an In Vivo Phage Display Screening.
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- Pharmaceutics, 2021, v. 13, n. 10, p. 1598, doi. 10.3390/pharmaceutics13101598
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- Article
Regional distribution of polymorphisms associated to the disease-causing gene of spinocerebellar ataxia type 3.
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- Journal of Neurology, 2025, v. 272, n. 1, p. 1, doi. 10.1007/s00415-024-12829-9
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- Publication type:
- Article
Regional distribution of polymorphisms associated to the disease-causing gene of spinocerebellar ataxia type 3.
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- Journal of Neurology, 2025, v. 272, n. 1, p. 1, doi. 10.1007/s00415-024-12829-9
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- Article
Correction to: The frequency of non‑motor symptoms in SCA3 and their association with disease severity and lifestyle factors.
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- 2024
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- Correction Notice
The frequency of non-motor symptoms in SCA3 and their association with disease severity and lifestyle factors.
- Published in:
- Journal of Neurology, 2023, v. 270, n. 2, p. 944, doi. 10.1007/s00415-022-11441-z
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- Article
Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado–Joseph disease models.
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- Human Molecular Genetics, 2019, v. 28, n. 22, p. 3691, doi. 10.1093/hmg/ddz097
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- Article
Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado–Joseph disease models.
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- Human Molecular Genetics, 2019, v. 28, n. 1, p. 51, doi. 10.1093/hmg/ddy328
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- Article
Loss of hierarchical imprinting regulation at the Prader–Willi/Angelman syndrome locus in human iPSCs.
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- Human Molecular Genetics, 2018, v. 27, n. 23, p. 3999, doi. 10.1093/hmg/ddy274
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- Article
Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease.
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- Human Molecular Genetics, 2015, v. 24, n. 19, p. 5451, doi. 10.1093/hmg/ddv271
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- Article
Calpain inhibition reduces ataxin-3 cleavage alleviating neuropathology and motor impairments in mouse models of Machado–Joseph disease.
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- Human Molecular Genetics, 2014, v. 23, n. 18, p. 4932, doi. 10.1093/hmg/ddu209
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- Article
Neuropeptide Y (NPY) intranasal delivery alleviates Machado–Joseph disease.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-82339-5
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- Article
Differential Temporal Dynamics of Axial and Appendicular Ataxia in SCA3.
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- 2022
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- Publication type:
- journal article
Characterization of Lifestyle in Spinocerebellar Ataxia Type 3 and Association with Disease Severity.
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- Movement Disorders, 2022, v. 37, n. 2, p. 405, doi. 10.1002/mds.28844
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- Article