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APC/C-Cdh1-targeted substrates as potential therapies for Alzheimer’s disease.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1086540
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- Article
Amyloid-β Induces Cdh1-Mediated Rock2 Stabilization Causing Neurodegeneration.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.884470
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- Article
Preconditioning-Activated AKT Controls Neuronal Tolerance to Ischemia through the MDM2–p53 Pathway.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 14, p. 7275, doi. 10.3390/ijms22147275
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- Article
DJ1 represses glycolysis and cell proliferation by transcriptionally up-regulating pink1.
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- Biochemical Journal, 2015, v. 467, n. 2, p. 303, doi. 10.1042/BJ20141025
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- Article
Roles of Microglial Ion Channel in Neurodegenerative Diseases.
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- Journal of Clinical Medicine, 2021, v. 10, n. 6, p. 1239, doi. 10.3390/jcm10061239
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- Article
Neuroprotective Role of Antidiabetic Drug Metformin Against Apoptotic Cell Death in Primary Cortical Neurons.
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- Journal of Molecular Neuroscience, 2008, v. 34, n. 1, p. 77, doi. 10.1007/s12031-007-9002-1
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- Article
Cdk5-mediated inhibition of APC/C-Cdh1 switches on the cyclin D1-Cdk4-pRb pathway causing aberrant S-phase entry of postmitotic neurons.
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- Scientific Reports, 2015, p. 18180, doi. 10.1038/srep18180
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- Article
Glutamate Excitoxicity Is the Key Molecular Mechanism Which Is Influenced by Body Temperature during the Acute Phase of Brain Stroke.
- Published in:
- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0044191
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- Article
Inhibition of mitochondrial respiration by nitric oxide: Its role in glucose metabolism and neuroprotection.
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- Journal of Neuroscience Research, 2005, v. 79, n. 1/2, p. 166, doi. 10.1002/jnr.20281
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- Article
Mitochondrial sodium/calcium exchanger NCLX regulates glycolysis in astrocytes, impacting on cognitive performance.
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- Journal of Neurochemistry, 2023, v. 165, n. 4, p. 521, doi. 10.1111/jnc.15745
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- Article
Cdh1/Hct1-APC Is Essential for the Survival of Postmitotic Neurons.
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- Journal of Neuroscience, 2005, v. 25, n. 36, p. 8115, doi. 10.1523/JNEUROSCI.1143-05.2005
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- Article
Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity.
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- EMBO Journal, 2008, v. 27, n. 20, p. 2736, doi. 10.1038/emboj.2008.195
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- Publication type:
- Article
Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-48196-z
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- Article
The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1.
- Published in:
- Nature Cell Biology, 2009, v. 11, n. 6, p. 747, doi. 10.1038/ncb1881
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- Article
Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway.
- Published in:
- Nature Cell Biology, 2004, v. 6, n. 1, p. 45, doi. 10.1038/ncb1080
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- Article
Regulatory T cells modulate inflammation and reduce infarct volume in experimental brain ischaemia.
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- Journal of Cellular & Molecular Medicine, 2014, v. 18, n. 8, p. 1571, doi. 10.1111/jcmm.12304
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- Article
PINK1 deficiency sustains cell proliferation by reprogramming glucose metabolism through HIF1.
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- Nature Communications, 2014, v. 5, n. 7, p. 4514, doi. 10.1038/ncomms5514
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- Article
APC/C-Cdh1 coordinates neurogenesis and cortical size during development.
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- Nature Communications, 2013, v. 4, n. 12, p. 2879, doi. 10.1038/ncomms3879
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- Article
Mitochondrial Complex I Activity is Conditioned by Supercomplex I-IIIIV Assembly in Brain Cells: Relevance for Parkinson's Disease.
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- Neurochemical Research, 2017, v. 42, n. 6, p. 1676, doi. 10.1007/s11064-017-2191-2
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- Article
A novel human Cdh1 mutation impairs anaphase promoting complex/cyclosome activity resulting in microcephaly, psychomotor retardation, and epilepsy.
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- Journal of Neurochemistry, 2019, v. 151, n. 1, p. 103, doi. 10.1111/jnc.14828
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- Publication type:
- Article
Human neuroblastoma cells with MYCN amplification are selectively resistant to oxidative stress by transcriptionally up-regulating glutamate cysteine ligase.
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- Journal of Neurochemistry, 2010, v. 113, n. 4, p. 819, doi. 10.1111/j.1471-4159.2010.06648.x
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- Article
Group IIA secretory phospholipase A<sub>2</sub> (GIIA) mediates apoptotic death during NMDA receptor activation in rat primary cortical neurons.
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- Journal of Neurochemistry, 2010, v. 112, n. 6, p. 1574, doi. 10.1111/j.1471-4159.2010.06567.x
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- Article
Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: assessment of the protective effects of glycoursodeoxycholic acid.
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- Journal of Neurochemistry, 2010, v. 112, n. 1, p. 56, doi. 10.1111/j.1471-4159.2009.06429.x
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- Article
Inflammation status after retinal detachment could be modulate by TP53 gene.
- Published in:
- 2024
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- Publication type:
- Abstract
Cross-talk between energy and redox metabolism in astrocyte-neuron functional cooperation.
- Published in:
- Essays in Biochemistry, 2023, v. 67, n. 1, p. 17, doi. 10.1042/EBC20220075
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- Article
Genetic determinants of neuronal vulnerability to apoptosis.
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- Cellular & Molecular Life Sciences, 2013, v. 70, n. 1, p. 71, doi. 10.1007/s00018-012-1029-y
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- Article
Effect of Reperfusion Following Cerebral Ischaemia on the Activity of the Mitochondrial Respiratory Chain in the Gerbil Brain.
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- Journal of Neurochemistry, 1995, v. 65, n. 4, p. 1698, doi. 10.1046/j.1471-4159.1995.65041698.x
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- Article
Changes of Respiratory Chain Activity in Mitochondrial and Synaptosomal Fractions Isolated from the Gerbil Brain After Graded Ischaemia.
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- Journal of Neurochemistry, 1995, v. 64, n. 5, p. 2222, doi. 10.1046/j.1471-4159.1995.64052222.x
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- Article
Pursuing precision in medicine and nutrition: the rise of electrochemical biosensing at the molecular level.
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- Analytical & Bioanalytical Chemistry, 2024, v. 416, n. 9, p. 2151, doi. 10.1007/s00216-023-04805-5
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- Article
Mitochondrial–nuclear p53 trafficking controls neuronal susceptibility in stroke.
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- IUBMB Life, 2021, v. 73, n. 3, p. 582, doi. 10.1002/iub.2453
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- Article
The pentose-phosphate pathway in neuronal survival against nitrosative stress.
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- IUBMB Life, 2010, v. 62, n. 1, p. 14, doi. 10.1002/iub.280
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- Publication type:
- Article
Inhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathway.
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- Journal of Neurochemistry, 2007, v. 102, n. 1, p. 194, doi. 10.1111/j.1471-4159.2007.04450.x
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- Publication type:
- Article
Increased mitochondrial respiration maintains the mitochondrial membrane potential and promotes survival of cerebellar neurons in an endogenous model of glutamate receptor activation.
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- Journal of Neurochemistry, 2005, v. 92, n. 1, p. 183, doi. 10.1111/j.1471-4159.2004.02851.x
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- Publication type:
- Article
A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation....
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- Journal of Neurochemistry, 2001, v. 77, n. 2, p. 676, doi. 10.1046/j.1471-4159.2001.00276.x
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- Publication type:
- Article
D-Glucose Prevents Glutathione Oxidation and Mitochondrial Damage After Glutamate Receptor Stimulation in Rat Cortical Primary Neurons.
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- Journal of Neurochemistry, 2000, v. 75, n. 4, p. 1618, doi. 10.1046/j.1471-4159.2000.0751618.x
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- Article
Peroxynitrite Anion Stimulates Arginine Release from Cultured Rat Astrocytes.
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- Journal of Neurochemistry, 1999, v. 73, n. 4, p. 1446, doi. 10.1046/j.1471-4159.1999.0731446.x
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- Publication type:
- Article
SHORT-TERM EFFECTS OF GLUTAMATE RECEPTOR STIMULATION ON NEURONAL ENERGY METABOLISM.
- Published in:
- 1999
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- Publication type:
- Abstract
Induction of Glucose-6-Phosphate Dehydrogenase by Lipopolysaccharide Contributes to Preventing Nitric Oxide-Mediated Glutathione Depletion in Cultured Rat Astrocytes.
- Published in:
- Journal of Neurochemistry, 1999, v. 72, n. 4, p. 1750, doi. 10.1046/j.1471-4159.1999.721750.x
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- Publication type:
- Article
Nitric Oxide-Mediated Mitochondrial Damage in the Brain: Mechanisms and Implications for Neurodegenerative Diseases.
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- Journal of Neurochemistry, 1997, v. 68, n. 6, p. 2227, doi. 10.1046/j.1471-4159.1997.68062227.x
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- Publication type:
- Article
A Missense Variant in TP53 Could Be a Genetic Biomarker Associated with Bone Tissue Alterations.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 3, p. 1395, doi. 10.3390/ijms25031395
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- Publication type:
- Article
Regulation of APC/C-Cdh1 and Its Function in Neuronal Survival.
- Published in:
- Molecular Neurobiology, 2012, v. 46, n. 3, p. 547, doi. 10.1007/s12035-012-8309-2
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- Publication type:
- Article
Regulation of Bcl-xL-ATP Synthase Interaction by Mitochondrial Cyclin B1-Cyclin-Dependent Kinase-1 Determines Neuronal Survival.
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- Journal of Neuroscience, 2015, v. 35, n. 25, p. 9287, doi. 10.1523/JNEUROSCI.4712-14.2015
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- Article