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Immune checkpoint therapy: Forging ahead.
- Published in:
- Science Translational Medicine, 2022, v. 14, n. 670, p. 1, doi. 10.1126/scitranslmed.adf2947
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- Publication type:
- Article
Pilot study of Tremelimumab with and without cryoablation in patients with metastatic renal cell carcinoma.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26415-4
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- Publication type:
- Article
Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25188-0
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- Article
Frontiers in cancer immunotherapy—a symposium report.
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- Annals of the New York Academy of Sciences, 2021, v. 1489, n. 1, p. 30, doi. 10.1111/nyas.14526
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- Publication type:
- Article
ARID1A mutation plus CXCL13 expression act as combinatorial biomarkers to predict responses to immune checkpoint therapy in mUCC.
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- Science Translational Medicine, 2020, v. 12, n. 548, p. 1, doi. 10.1126/scitranslmed.abc4220
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- Article
Neoantigen responses, immune correlates, and favorable outcomes after ipilimumab treatment of patients with prostate cancer.
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- Science Translational Medicine, 2020, v. 12, n. 537, p. 1, doi. 10.1126/scitranslmed.aaz3577
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- Publication type:
- Article
Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy.
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- 2018
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- Publication type:
- journal article
Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer.
- Published in:
- Nature Communications, 2017, v. 8, n. 4, p. 15095, doi. 10.1038/ncomms15095
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- Publication type:
- Article
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.
- Published in:
- Nature Communications, 2017, v. 8, n. 2, p. 14340, doi. 10.1038/ncomms14340
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- Publication type:
- Article
Selective inhibition of autoimmune exacerbation while preserving the antitumor clinical benefit using IL-6 blockade in a patient with advanced melanoma and Crohn’s disease: a case report.
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- Journal of Hematology & Oncology, 2016, v. 9, p. 1, doi. 10.1186/s13045-016-0309-7
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- Article
Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy.
- Published in:
- Nature Communications, 2016, v. 7, n. 8, p. 12335, doi. 10.1038/ncomms12335
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- Article
Immune Checkpoint Blockade in Cancer Therapy: The 2015 Lasker-DeBakey Clinical Medical Research Award.
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- 2015
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- Publication type:
- journal article
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis.
- Published in:
- Nature Medicine, 2015, v. 21, n. 9, p. 998, doi. 10.1038/nm.3902
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- Publication type:
- Article
Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25.
- Published in:
- Cell Research, 2015, v. 25, n. 3, p. 399, doi. 10.1038/cr.2015.28
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- Publication type:
- Article
Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25.
- Published in:
- Cell Research, 2015, v. 25, n. 2, p. 208, doi. 10.1038/cr.2015.3
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- Publication type:
- Article
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens.
- Published in:
- Nature, 2014, v. 515, n. 7528, p. 577, doi. 10.1038/nature13988
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- Publication type:
- Article
Localized Oncolytic Virotherapy Overcomes Systemic Tumor Resistance to Immune Checkpoint Blockade Immunotherapy.
- Published in:
- Science Translational Medicine, 2014, v. 6, n. 226, p. 1, doi. 10.1126/scitranslmed.3008095
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- Publication type:
- Article
Development of ipilimumab: a novel immunotherapeutic approach for the treatment of advanced melanoma.
- Published in:
- Annals of the New York Academy of Sciences, 2013, v. 1291, n. 1, p. 1, doi. 10.1111/nyas.12180
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- Publication type:
- Article
Repertoire Enhancement with Adoptively Transferred Female Lymphocytes Controls the Growth of Pre-Implanted Murine Prostate Cancer.
- Published in:
- PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035222
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- Publication type:
- Article
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting.
- Published in:
- Nature, 2012, v. 482, n. 7385, p. 400, doi. 10.1038/nature10755
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- Article
Nobels: Toll pioneers deserve recognition.
- Published in:
- 2011
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- Publication type:
- Letter
Novel cancer immunotherapy agents with survival benefit: recent successes and next steps.
- Published in:
- 2011
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- Publication type:
- journal article
Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido.
- Published in:
- Nature Medicine, 2011, v. 17, n. 9, p. 1094, doi. 10.1038/nm.2438
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- Publication type:
- Article
Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication.
- Published in:
- Immunological Reviews, 2011, v. 241, n. 1, p. 104, doi. 10.1111/j.1600-065X.2011.01007.x
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- Publication type:
- Article
Combination CTLA-4 Blockade and 4-1BB Activation Enhances Tumor Rejection by Increasing T-Cell Infiltration, Proliferation, and Cytokine Production.
- Published in:
- PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0019499
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- Publication type:
- Article
Attenuated T Cell Responses to a High-Potency Ligand In Vivo.
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- PLoS Biology, 2010, v. 8, n. 9, p. 1, doi. 10.1371/journal.pbio.1000481
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- Publication type:
- Article
Single-institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting: lymphocyte count after 2 doses correlates with survival.
- Published in:
- 2010
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- Publication type:
- journal article
Single-Institution Experience With Ipilimumab in Advanced Melanoma Patients in the Compassionate Use Setting.
- Published in:
- Cancer (0008543X), 2010, v. 116, n. 7, p. 1767, doi. 10.1002/cncr.24951
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- Publication type:
- Article
Negative regulators of T-cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections.
- Published in:
- Immunological Reviews, 2009, v. 229, n. 1, p. 67, doi. 10.1111/j.1600-065X.2009.00763.x
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- Publication type:
- Article
Local secretion of anti-CTLA-4 enhances the therapeutic efficacy of a cancer immunotherapy with reduced evidence of systemic autoimmunity.
- Published in:
- Cancer Immunology, Immunotherapy, 2008, v. 57, n. 8, p. 1263, doi. 10.1007/s00262-008-0451-3
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- Publication type:
- Article
Cell intrinsic mechanisms of T-cell inhibition and application to cancer therapy.
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- Immunological Reviews, 2008, v. 224, n. 1, p. 141, doi. 10.1111/j.1600-065X.2008.00649.x
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- Publication type:
- Article
To be or not to be B7.
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- Journal of Clinical Investigation, 2006, v. 116, n. 10, p. 2590, doi. 10.1172/JCI30103
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- Publication type:
- Article
To be or not to be B7.
- Published in:
- Journal of Clinical Investigation, 2006, v. 116, n. 10, p. 2590, doi. 10.1172/JCI30103
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- Publication type:
- Article
To be or not to be B7.
- Published in:
- 2006
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- Publication type:
- journal article
CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells.
- Published in:
- Journal of Clinical Investigation, 2006, v. 116, n. 7, p. 1935, doi. 10.1172/JCI27745
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- Publication type:
- Article
Restoring function in exhausted CD8 T cells during chronic viral infection.
- Published in:
- Nature, 2006, v. 439, n. 7077, p. 682, doi. 10.1038/nature04444
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- Article
Breaking down the barriers to cancer immunotherapy.
- Published in:
- Nature Immunology, 2005, v. 6, n. 12, p. 1207, doi. 10.1038/ni1205-1207
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- Publication type:
- Article
Co-stimulatory pathways in lymphocyte regulation: the immunoglobulin superfamily.
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- British Journal of Haematology, 2005, v. 130, n. 6, p. 809, doi. 10.1111/j.1365-2141.2005.05627.x
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- Publication type:
- Article
MHC class II‐independent and ‐dependent T cell expansion and B cell hyperactivity in vivo in mice deficient in CD152 (CTLA‐4).
- Published in:
- International Immunology, 2004, v. 16, n. 7, p. 895
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- Publication type:
- Article
BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1.
- Published in:
- Nature Immunology, 2003, v. 4, n. 7, p. 670, doi. 10.1038/ni944
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- Publication type:
- Article
Prostate Cancer: Advances in Immunotherapy.
- Published in:
- BioDrugs, 2003, v. 17, n. 2, p. 131, doi. 10.2165/00063030-200317020-00005
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- Publication type:
- Article
CTLA-4: new insights into its biological function and use in tumor immunotherapy.
- Published in:
- Nature Immunology, 2002, v. 3, n. 7, p. 611, doi. 10.1038/ni0702-611
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- Publication type:
- Article
ICOS co-stimulatory receptor is essential for T-cell activation and function.
- Published in:
- Nature, 2001, v. 409, n. 6816, p. 97, doi. 10.1038/35051100
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- Publication type:
- Article
Secondary but not primary T cell responses are enhanced in CTLA-4-deficient CD8.
- Published in:
- European Journal of Immunology, 1998, v. 28, n. 10, p. 3137, doi. 10.1002/(SICI)1521-4141(199810)28:10<3137::AID-IMMU3137>3.0.CO;2-X
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- Publication type:
- Article
Enhancement of the anti-tumor immune response using a combination of interferon-γ and B7 expression in an experimental mammary carcinoma.
- Published in:
- International Journal of Cancer, 1998, v. 77, n. 1, p. 107, doi. 10.1002/(SICI)1097-0215(19980703)77:1<107::AID-IJC17>3.0.CO;2-B
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- Publication type:
- Article
The role of tyrosine phosphorylation and PTP-1C in CTLA-4 signal transduction.
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- European Journal of Immunology, 1996, v. 26, n. 12, p. 3224, doi. 10.1002/eji.1830261257
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- Publication type:
- Article
Superantigen responses and co-stimulation: CD28 and CTLA-4 have opposing effects on T cell expansion in vitro and in vivo.
- Published in:
- International Immunology, 1996, v. 8, n. 4, p. 519, doi. 10.1093/intimm/8.4.519
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- Publication type:
- Article
Characterization of env gene recombination in X-ray-induced thymomas of C57BL76 mice.
- Published in:
- Molecular Carcinogenesis, 1989, v. 2, n. 3, p. 126, doi. 10.1002/mc.2940020304
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- Publication type:
- Article
Antibodies against the T cell receptor/CD3 complex interfere with distinct intra-thymic cell-cell interactions in vivo: correlation with arrest of T cell differentiation.
- Published in:
- European Journal of Immunology, 1989, v. 19, n. 5, p. 857, doi. 10.1002/eji.1830190512
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- Publication type:
- Article
Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors.
- Published in:
- Nature, 1988, v. 335, n. 6189, p. 443, doi. 10.1038/335443a0
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- Publication type:
- Article