Works by Ali, Taha F. S.

Results: 22

Indole-based FLT3 inhibitors and related scaffolds as potential therapeutic agents for acute myeloid leukemia.

Published in:

BMC Chemistry, 2023, v. 17, n. 1, p. 1, doi. 10.1186/s13065-023-00981-8

By:

Ezelarab, Hend A. A.;
Ali, Taha F. S.;
Abbas, Samar H.;
Hassan, Heba A.;
Beshr, Eman A. M.

Publication type:

Article

Cyclodextrin Enhances Corneal Tolerability and Reduces Ocular Toxicity Caused by Diclofenac.

Published in:

Oxidative Medicine & Cellular Longevity, 2018, p. 1, doi. 10.1155/2018/5260976

By:

Abdelkader, Hamdy;
Fathalla, Zeinab;
Moharram, Hossam;
Ali, Taha F. S.;
Pierscionek, Barbara

Publication type:

Article

Antiproliferative potential of moluccella laevis L. aerial parts family lamiaceae (labiatae), supported by phytochemical investigation and molecular docking study.

Published in:

Natural Product Research, 2022, v. 36, n. 5, p. 1391, doi. 10.1080/14786419.2021.1876046

By:

Hamed, Ashraf N. E.;
Abdelaty, Nousiba A.;
Attia, Eman Z.;
Amin, Mohamed N.;
Ali, Taha F. S.;
Afifi, Ahmed H.;
Abdelmohsen, Usama R.;
Desoukey, Samar Y.

Publication type:

Article

Antidepressant potential of Mesembryanthemum cordifolium roots assisted by metabolomic analysis and virtual screening.

Published in:

Natural Product Research, 2021, v. 35, n. 23, p. 5493, doi. 10.1080/14786419.2020.1788019

By:

Said, Asmaa Abo Elgoud;
Ali, Taha F. S.;
Attia, Eman Zekry;
Ahmed, Al-Shaimaa F.;
Shehata, Alaa H.;
Abdelmohsen, Usama Ramadan;
Fouad, Mostafa Ahmed

Publication type:

Article

Discovery and Anticancer Screening of Novel Oxindole-Based Derivative Bearing Pyridyl Group as Potent and Selective Dual FLT3/CDK2 Kinase Inhibitor.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 5, p. 659, doi. 10.3390/ph17050659

By:

Soudi, Aya;
Bender, Onur;
Celik, Ismail;
El-Hafeez, Amer Ali Abd;
Dogan, Rumeysa;
Atalay, Arzu;
Elkaeed, Eslam B.;
Alsfouk, Aisha A.;
Abdelhafez, Elshimaa M. N.;
Aly, Omar M.;
Sippl, Wolfgang;
Ali, Taha F. S.

Publication type:

Article

Discovery of Azaindolin-2-One as a Dual Inhibitor of GSK3β and Tau Aggregation with Potential Neuroprotective Activity.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 4, p. N.PAG, doi. 10.3390/ph15040426

By:

Ali, Taha F. S.;
Ciftci, Halil I.;
Radwan, Mohamed O.;
Roshdy, Eslam;
Shawky, Ahmed M.;
Abourehab, Mohammed A. S.;
Tateishi, Hiroshi;
Otsuka, Masami;
Fujita, Mikako

Publication type:

Article

New Multi-Targeted Antiproliferative Agents: Design and Synthesis of IC261-Based Oxindoles as Potential Tubulin, CK1 and EGFR Inhibitors.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 11, p. 1114, doi. 10.3390/ph14111114

By:

Fareed, Momen R.;
Shoman, Mai E.;
Hamed, Mohammed I. A.;
Badr, Mohamed;
Bogari, Hanin A.;
Elhady, Sameh S.;
Ibrahim, Tarek S.;
Abuo-Rahma, Gamal El-Din A.;
Ali, Taha F. S.

Publication type:

Article

In silico drug discovery of SIRT2 inhibitors from natural source as anticancer agents.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-28226-7

By:

Ibrahim, Mahmoud A. A.;
Abdeljawaad, Khlood A. A.;
Roshdy, Eslam;
Mohamed, Dina E. M.;
Ali, Taha F. S.;
Gabr, Gamal A.;
Jaragh-Alhadad, Laila A.;
Mekhemer, Gamal A. H.;
Shawky, Ahmed M.;
Sidhom, Peter A.;
Abdelrahman, Alaa H. M.

Publication type:

Article

In silico drug discovery of SIRT2 inhibitors from natural source as anticancer agents.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-28226-7

By:

Ibrahim, Mahmoud A. A.;
Abdeljawaad, Khlood A. A.;
Roshdy, Eslam;
Mohamed, Dina E. M.;
Ali, Taha F. S.;
Gabr, Gamal A.;
Jaragh-Alhadad, Laila A.;
Mekhemer, Gamal A. H.;
Shawky, Ahmed M.;
Sidhom, Peter A.;
Abdelrahman, Alaa H. M.

Publication type:

Article

Applying Different Techniques to Improve the Bioavailability of Candesartan Cilexetil Antihypertensive Drug.

Published in:

Drug Design, Development & Therapy, 2020, v. 14, p. 1851, doi. 10.2147/dddt.s248511

By:

Aly, Usama Farghaly;
Sarhan, Hatem Abdelmonsef;
Ali, Taha F. S.;
Sharkawy, Hosny Abd El-Bakey

Publication type:

Article

Novel Inhibitor for Downstream Targeting of Transforming Growth Factor-β Signaling to Suppress Epithelial to Mesenchymal Transition and Cell Migration.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 5047, doi. 10.3390/ijms23095047

By:

Toma, Tsugumasa;
Tateishi, Hiroshi;
Kawakami, Kensaku;
Ali, Taha F. S.;
Kamo, Masahiro;
Monde, Kazuaki;
Nakashima, Yuta;
Fujita, Mikako;
Otsuka, Masami

Publication type:

Article

Design, synthesis, in silico studies, and apoptotic antiproliferative activity of novel thiazole-2-acetamide derivatives as tubulin polymerization inhibitors.

Published in:

Frontiers in Chemistry, 2025, p. 1, doi. 10.3389/fchem.2025.1565699

By:

Al-Wahaibi, Lamya H.;
Elshamsy, Ali M.;
Ali, Taha F. S.;
Youssif, Bahaa G. M.;
Bräse, Stefan;
Abdel-Aziz, Mohamed;
El-Koussi, Nawal A.

Publication type:

Article

An antifibrotic compound that ameliorates hyperglycaemia and fat accumulation in cell and HFD mouse models.

Published in:

Diabetologia, 2024, v. 67, n. 11, p. 2568, doi. 10.1007/s00125-024-06260-y

By:

Toma, Tsugumasa;
Miyakawa, Nobukazu;
Arakaki, Yuiichi;
Watanabe, Takuro;
Nakahara, Ryosei;
Ali, Taha F. S.;
Biswas, Tanima;
Todaka, Mikio;
Kondo, Tatsuya;
Fujita, Mikako;
Otsuka, Masami;
Araki, Eiichi;
Tateishi, Hiroshi

Publication type:

Article

A Dithiol Compound Binds to the Zinc Finger Protein TRAF6 and Suppresses Its Ubiquitination.

Published in:

ChemMedChem, 2017, v. 12, n. 23, p. 1935, doi. 10.1002/cmdc.201700399

By:

Koga, Ryoko;
Radwan, Mohamed O.;
Ejima, Tomohiko;
Kanemaru, Yosuke;
Tateishi, Hiroshi;
Ali, Taha F. S.;
Ciftci, Halil Ibrahim;
Shibata, Yuri;
Taguchi, Yuu;
Inoue, Jun‐ichiro;
Otsuka, Masami;
Fujita, Mikako

Publication type:

Article

Front Cover: A Dithiol Compound Binds to the Zinc Finger Protein TRAF6 and Suppresses Its Ubiquitination (ChemMedChem 23/2017).

Published in:

ChemMedChem, 2017, v. 12, n. 23, p. 1906, doi. 10.1002/cmdc.201700735

By:

Koga, Ryoko;
Radwan, Mohamed O.;
Ejima, Tomohiko;
Kanemaru, Yosuke;
Tateishi, Hiroshi;
Ali, Taha F. S.;
Ciftci, Halil Ibrahim;
Shibata, Yuri;
Taguchi, Yuu;
Inoue, Jun‐ichiro;
Otsuka, Masami;
Fujita, Mikako

Publication type:

Article

Discovery of oxindole‐based FLT3 inhibitors as a promising therapeutic lead for acute myeloid leukemia carrying the oncogenic ITD mutation.

Published in:

Archiv der Pharmazie, 2023, v. 356, n. 2, p. 1, doi. 10.1002/ardp.202200407

By:

Bender, Onur;
Shoman, Mai E.;
Ali, Taha F. S.;
Dogan, Rumeysa;
Celik, Ismail;
Mollica, Adriano;
Hamed, Mohammed I. A.;
Aly, Omar M.;
Alamri, Abdulwahab;
Alanazi, Jowaher;
Ahemad, Nafees;
Gan, Siew Hua;
Malik, Jonaid Ahmad;
Anwar, Sirajudheen;
Atalay, Arzu;
Beshr, Eman A. M.

Publication type:

Article

New antiproliferative 3-substituted oxindoles inhibiting EGFR/VEGFR-2 and tubulin polymerization.

Published in:

Molecular Diversity, 2024, v. 28, n. 2, p. 563, doi. 10.1007/s11030-023-10603-z

By:

Ezelarab, Hend A. A.;
Ali, Taha F. S.;
Abbas, Samar H.;
Sayed, Ahmed M.;
Beshr, Eman A. M.;
Hassan, Heba A.

Publication type:

Article

Design and synthesis of new dihydropyrimidine/sulphonamide hybrids as promising anti-inflammatory agents via dual mPGES-1/5-LOX inhibition.

Published in:

Frontiers in Chemistry, 2024, p. 1, doi. 10.3389/fchem.2024.1387923

By:

Al-Wahaibi, Lamya H.;
Elshamsy, Ali M.;
Ali, Taha F. S.;
Youssif, Bahaa G. M.;
Brase, S.;
Abdel-Aziz, Mohamed;
El-Koussi, Nawal A.;
Lauro, Gianluigi

Publication type:

Article

Combination of an Oxindole Derivative with (−)-β-Elemene Alters Cell Death Pathways in FLT3/ITD + Acute Myeloid Leukemia Cells.

Published in:

Molecules, 2023, v. 28, n. 13, p. 5253, doi. 10.3390/molecules28135253

By:

Alanazi, Jowaher;
Bender, Onur;
Dogan, Rumeysa;
Malik, Jonaid Ahmad;
Atalay, Arzu;
Ali, Taha F. S.;
Beshr, Eman A. M.;
Shawky, Ahmed M.;
Aly, Omar M.;
Alqahtani, Yasir Nasser H.;
Anwar, Sirajudheen

Publication type:

Article

In Vitro and In Silico Evaluation of Anticancer Activity of New Indole-Based 1,3,4-Oxadiazoles as EGFR and COX-2 Inhibitors.

Published in:

Molecules, 2020, v. 25, n. 21, p. 5190, doi. 10.3390/molecules25215190

By:

Sever, Belgin;
Altıntop, Mehlika Dilek;
Özdemir, Ahmet;
Akalın Çiftçi, Gülşen;
Ellakwa, Doha E.;
Tateishi, Hiroshi;
Radwan, Mohamed O.;
Ibrahim, Mahmoud A. A.;
Otsuka, Masami;
Fujita, Mikako;
Ciftci, Halil I.;
Ali, Taha F. S.;
Cotelle, Philippe

Publication type:

Article

Antiproliferative S-Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement.

Published in:

Molecules, 2019, v. 24, n. 18, p. 3295, doi. 10.3390/molecules24183295

By:

Radwan, Mohamed O.;
Ciftci, Halil I.;
Ali, Taha F. S.;
Ellakwa, Doha E.;
Koga, Ryoko;
Tateishi, Hiroshi;
Nakata, Akiko;
Ito, Akihiro;
Yoshida, Minoru;
Okamoto, Yoshinari;
Fujita, Mikako;
Otsuka, Masami;
Sekeroglu, Nazim;
Kijjoa, Anake;
Gezici, Sevgi

Publication type:

Article

Design, Synthesis, and Biological Evaluation of Novel 1,3,4-Thiadiazole Derivatives as Potential Antitumor Agents against Chronic Myelogenous Leukemia: Striking Effect of Nitrothiazole Moiety.

Published in:

Molecules, 2018, v. 23, n. 1, p. 59, doi. 10.3390/molecules23010059

By:

Altıntop, Mehlika Dilek;
Ciftci, Halil Ibrahim;
Radwan, Mohamed O.;
Sever, Belgin;
Kaplancıklı, Zafer Asım;
Ali, Taha F. S.;
Koga, Ryoko;
Fujita, Mikako;
Otsuka, Masami;
Özdemir, Ahmet

Publication type:

Article