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DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-35876-8
By:
- Zhivagui, Maria;
- Hoda, Areebah;
- Valenzuela, Noelia;
- Yeh, Yi-Yu;
- Dai, Jason;
- He, Yudou;
- Nandi, Shuvro P.;
- Otlu, Burcak;
- Van Houten, Bennett;
- Alexandrov, Ludmil B.
Publication type:
Article
Insight into History of GCR Heavy Nuclei Fluxes by Their Tracks in Meteorites.
Published in:
Physics of Atomic Nuclei, 2022, v. 85, n. 5, p. 446, doi. 10.1134/S1063778822050039
By:
- Alexandrov, A. B.;
- Bagulya, A. V.;
- Babaev, P. A.;
- Chernyavsky, M. M.;
- Gippius, A. A.;
- Gorbunov, S. A.;
- Grachev, V. M.;
- Kalinina, G. V.;
- Konovalova, N. S.;
- Okateva, N. M.;
- Polukhina, N. G.;
- Rymzhanov, R. A.;
- Starkov, N. I.;
- Soe, Than Naing;
- Shchedrina, T. V.;
- Volkov, A. E.;
- Voronkov, R. A.
Publication type:
Article
Muography of Large Natural and Industrial Objects.
Published in:
Physics of Atomic Nuclei, 2021, v. 84, n. 6, p. 1114, doi. 10.1134/S1063778821130032
By:
- Alexandrov, A. B.;
- Chernyavsky, M. M.;
- Galkin, V. I.;
- Goncharova, L. A.;
- Grachev, V. M.;
- Konovalov, A. S.;
- Konovalova, N. S.;
- Korolev, P. S.;
- Larionov, A. A.;
- Managadze, A. K.;
- Melnichenko, I. A.;
- Okateva, N. M.;
- Polukhina, N. G.;
- Roganova, T. M.;
- Sadykov, Zh. T.;
- Shchedrina, T. V.;
- Shevchenko, V. I.;
- Starkov, N. I.;
- Tyukov, V. E.;
- Starkova, E. N.
Publication type:
Article
Search for Hidden Rooms in the Holy Trinity Danilov Monastery by the Muon Radiography Method.
Published in:
Physics of Atomic Nuclei, 2021, v. 84, n. 6, p. 855, doi. 10.1134/S1063778821060028
By:
- Alexandrov, A. B.;
- Vasina, S. G.;
- Galkin, V. I.;
- Goncharova, L. A.;
- Konovalov, A. S.;
- Konovalova, N. S.;
- Korolev, P. S.;
- Larionov, A. A.;
- Melnichenko, I. A.;
- Managadze, A. K.;
- Okateva, N. M.;
- Polukhina, N. G.;
- Roganova, T. M.;
- Sadykov, Zh. T.;
- Starkov, N. I.;
- Starkova, E. N.;
- Tioukov, V. E.;
- Chernyavsky, M. M.;
- Shevchenko, V. I.;
- Shchedrina, T. V.
Publication type:
Article
An overview of mutational and copy number signatures in human cancer.
Published in:
Journal of Pathology, 2022, v. 257, n. 4, p. 454, doi. 10.1002/path.5912
By:
- Steele, Christopher D;
- Pillay, Nischalan;
- Alexandrov, Ludmil B
Publication type:
Article
Mutational signature analysis identifies MUTYH deficiency in colorectal cancers and adrenocortical carcinomas.
Published in:
Journal of Pathology, 2017, v. 242, n. 1, p. 10, doi. 10.1002/path.4880
By:
- Pilati, Camilla;
- Shinde, Jayendra;
- Alexandrov, Ludmil B;
- Assié, Guillaume;
- André, Thierry;
- Hélias‐Rodzewicz, Zofia;
- Ducoudray, Romain;
- Le Corre, Delphine;
- Zucman‐Rossi, Jessica;
- Emile, Jean‐François;
- Bertherat, Jérôme;
- Letouzé, Eric;
- Laurent‐Puig, Pierre
Publication type:
Article
The role of structural parameters in DNA cyclization.
Published in:
BMC Bioinformatics, 2016, v. 17, p. 1, doi. 10.1186/s12859-016-0897-9
By:
- Alexandrov, Ludmil B.;
- Bishop, Alan R.;
- Rasmussen, Kim Ø.;
- Alexandrov, Boian S.
Publication type:
Article
Promoter polymorphisms in two overlapping 6p25 genes implicate mitochondrial proteins in cognitive deficit in schizophrenia.
Published in:
Molecular Psychiatry, 2012, v. 17, n. 12, p. 1328, doi. 10.1038/mp.2011.129
By:
- Jablensky, A;
- Angelicheva, D;
- Donohoe, G J;
- Cruickshank, M;
- Azmanov, D N;
- Morris, D W;
- McRae, A;
- Weickert, C S;
- Carter, K W;
- Chandler, D;
- Alexandrov, B;
- Usheva, A;
- Morar, B;
- Verbrugghe, P L;
- Filipovska, A;
- Rackham, O;
- Bishop, A R;
- Rasmussen, K Ø;
- Dragovic, M;
- Cooper, M
Publication type:
Article
DNA dynamics play a role as a basal transcription factor in the positioning and regulation of gene transcription initiation.
Published in:
Nucleic Acids Research, 2010, v. 38, n. 6, p. 1790, doi. 10.1093/nar/gkp1084
By:
- Alexandrov, Boian S.;
- Gelev, Vladimir;
- Yoo, Sang Wook;
- Alexandrov, Ludmil B.;
- Fukuyo, Yayoi;
- Bishop, Alan R.;
- Rasmussen, Kim Ø.;
- Usheva, Anny
Publication type:
Article
A nonlinear dynamic model of DNA with a sequence-dependent stacking term.
Published in:
Nucleic Acids Research, 2009, v. 37, n. 7, p. 2405, doi. 10.1093/nar/gkp016
By:
- Alexandrov, Boian S.;
- Gelev, Vladimir;
- Monisova, Yevgeniya;
- Alexandrov, Ludmil B.;
- Bishop, Alan R.;
- Rasmussen, Kim Ø.;
- Usheva, Anny
Publication type:
Article
Expression and shedding of ICAM-1 in bladder cancer and its immunotherapy.
Published in:
International Journal of Cancer, 1993, v. 55, n. 6, p. 921, doi. 10.1002/ijc.2910550608
By:
- Jackson, Andrew M.;
- Alexandrov, Anton B.;
- Gribben, Shona C.;
- Esuvarnathan, K.;
- James, Keith
Publication type:
Article
Somatic mutational profiles and germline polygenic risk scores in human cancer.
Published in:
Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01016-y
By:
- Liu, Yuxi;
- Gusev, Alexander;
- Heng, Yujing J.;
- Alexandrov, Ludmil B.;
- Kraft, Peter
Publication type:
Article
Somatic mutational profiles and germline polygenic risk scores in human cancer.
Published in:
Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01016-y
By:
- Liu, Yuxi;
- Gusev, Alexander;
- Heng, Yujing J.;
- Alexandrov, Ludmil B.;
- Kraft, Peter
Publication type:
Article
Control-independent mosaic single nucleotide variant detection with DeepMosaic.
Published in:
Nature Biotechnology, 2023, v. 41, n. 6, p. 870, doi. 10.1038/s41587-022-01559-w
By:
- Yang, Xiaoxu;
- Xu, Xin;
- Breuss, Martin W.;
- Antaki, Danny;
- Ball, Laurel L.;
- Chung, Changuk;
- Shen, Jiawei;
- Li, Chen;
- George, Renee D.;
- Wang, Yifan;
- Bae, Taejeong;
- Cheng, Yuhe;
- Abyzov, Alexej;
- Wei, Liping;
- Alexandrov, Ludmil B.;
- Sebat, Jonathan L.;
- NIMH Brain Somatic Mosaicism Network;
- Averbuj, Dan;
- Roy, Subhojit;
- Courchesne, Eric
Publication type:
Article
Subclonal diversification of primary breast cancer revealed by multiregion sequencing.
Published in:
Nature Medicine, 2015, v. 21, n. 7, p. 751, doi. 10.1038/nm.3886
By:
- Yates, Lucy R;
- Gerstung, Moritz;
- Knappskog, Stian;
- Desmedt, Christine;
- Gundem, Gunes;
- Van Loo, Peter;
- Aas, Turid;
- Alexandrov, Ludmil B;
- Larsimont, Denis;
- Davies, Helen;
- Li, Yilong;
- Ju, Young Seok;
- Ramakrishna, Manasa;
- Haugland, Hans Kristian;
- Lilleng, Peer Kaare;
- Nik-Zainal, Serena;
- McLaren, Stuart;
- Butler, Adam;
- Martin, Sancha;
- Glodzik, Dominic
Publication type:
Article
Corrigendum: Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.
Published in:
Nature Genetics, 2015, v. 47, n. 6, p. 689, doi. 10.1038/ng0615-689b
By:
- Cooper, Colin S;
- Eeles, Rosalind;
- Wedge, David C;
- Van Loo, Peter;
- Gundem, Gunes;
- Alexandrov, Ludmil B;
- Kremeyer, Barbara;
- Butler, Adam;
- Lynch, Andrew G;
- Camacho, Niedzica;
- Massie, Charlie E;
- Kay, Jonathan;
- Luxton, Hayley J;
- Edwards, Sandra;
- Kote-Jarai, Zsofia;
- Dennis, Nening;
- Merson, Sue;
- Leongamornlert, Daniel;
- Zamora, Jorge;
- Corbishley, Cathy
Publication type:
Article
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets.
Published in:
Nature Genetics, 2015, v. 47, n. 5, p. 505, doi. 10.1038/ng.3252
By:
- Schulze, Kornelius;
- Imbeaud, Sandrine;
- Letouzé, Eric;
- Rebouissou, Sandra;
- Couchy, Gabrielle;
- Meiller, Clément;
- Shinde, Jayendra;
- Soysouvanh, Frederic;
- Calatayud, Anna-Line;
- Pelletier, Laura;
- Calvo, Fabien;
- Nault, Jean-Charles;
- Bioulac-Sage, Paulette;
- Stratton, Michael R;
- Llovet, Josep M;
- Zucman-Rossi, Jessica;
- Alexandrov, Ludmil B;
- Calderaro, Julien;
- Pinyol, Roser;
- Balabaud, Charles
Publication type:
Article
Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.
Published in:
Nature Genetics, 2015, v. 47, n. 4, p. 367, doi. 10.1038/ng.3221
By:
- Cooper, Colin S;
- Clark, Jeremy;
- Hurst, Rachel;
- Mithen, Richard;
- Bristow, Robert G;
- Boutros, Paul C;
- Fraser, Michael;
- Greenman, Christopher;
- Berney, Dan;
- Voet, Thierry;
- Easton, Douglas;
- Warren, Anne Y;
- Eeles, Rosalind;
- Foster, Christopher S;
- Brewer, Daniel S;
- Neal, David E;
- Wedge, David C;
- Gundem, Gunes;
- Alexandrov, Ludmil B;
- Kremeyer, Barbara
Publication type:
Article
Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer.
Published in:
Nature Genetics, 2014, v. 46, n. 5, p. 487, doi. 10.1038/ng.2955
By:
- Nik-Zainal, Serena;
- Wedge, David C;
- Alexandrov, Ludmil B;
- Petljak, Mia;
- Butler, Adam P;
- Bolli, Niccolo;
- Davies, Helen R;
- Knappskog, Stian;
- Martin, Sancha;
- Papaemmanuil, Elli;
- Ramakrishna, Manasa;
- Shlien, Adam;
- Simonic, Ingrid;
- Xue, Yali;
- Tyler-Smith, Chris;
- Campbell, Peter J;
- Stratton, Michael R
Publication type:
Article
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.
Published in:
Nature Genetics, 2014, v. 46, n. 2, p. 116, doi. 10.1038/ng.2874
By:
- Papaemmanuil, Elli;
- Rapado, Inmaculada;
- Li, Yilong;
- Potter, Nicola E;
- Wedge, David C;
- Tubio, Jose;
- Alexandrov, Ludmil B;
- Van Loo, Peter;
- Cooke, Susanna L;
- Marshall, John;
- Martincorena, Inigo;
- Hinton, Jonathan;
- Gundem, Gunes;
- van Delft, Frederik W;
- Nik-Zainal, Serena;
- Jones, David R;
- Ramakrishna, Manasa;
- Titley, Ian;
- Stebbings, Lucy;
- Leroy, Catherine
Publication type:
Article
Inactivating CUX1 mutations promote tumorigenesis.
Published in:
Nature Genetics, 2014, v. 46, n. 1, p. 33, doi. 10.1038/ng.2846
By:
- Wong, Chi C;
- Martincorena, Inigo;
- Rust, Alistair G;
- Rashid, Mamunur;
- Alifrangis, Constantine;
- Alexandrov, Ludmil B;
- Tiffen, Jessamy C;
- Kober, Christina;
- Green, Anthony R;
- Massie, Charles E;
- Nangalia, Jyoti;
- Lempidaki, Stella;
- Döhner, Hartmut;
- Döhner, Konstanze;
- Bray, Sarah J;
- McDermott, Ultan;
- Papaemmanuil, Elli;
- Campbell, Peter J;
- Adams, David J
Publication type:
Article
Assigning mutational signatures to individual samples and individual somatic mutations with SigProfilerAssignment.
Published in:
Bioinformatics, 2023, v. 39, n. 12, p. 1, doi. 10.1093/bioinformatics/btad756
By:
- Díaz-Gay, Marcos;
- Vangara, Raviteja;
- Barnes, Mark;
- Wang, Xi;
- Islam, S M Ashiqul;
- Vermes, Ian;
- Duke, Stephen;
- Narasimman, Nithish Bharadhwaj;
- Yang, Ting;
- Jiang, Zichen;
- Moody, Sarah;
- Senkin, Sergey;
- Brennan, Paul;
- Stratton, Michael R;
- Alexandrov, Ludmil B
Publication type:
Article
Examining clustered somatic mutations with SigProfilerClusters.
Published in:
Bioinformatics, 2022, v. 38, n. 13, p. 3470, doi. 10.1093/bioinformatics/btac335
By:
- Bergstrom, Erik N;
- Kundu, Mousumy;
- Tbeileh, Noura;
- Alexandrov, Ludmil B
Publication type:
Article
Experimental adaptive optics system.
Published in:
Optical Engineering, 1994, v. 33, n. 10, p. 3167, doi. 10.1117/12.178897
By:
- Alexandrov, Alexandr B.;
- Inshin, Pavel P.;
- Tyapin, Vjatcheslav V.
Publication type:
Article
Stem cell replication, somatic mutations and role of randomness in the development of cancer.
Published in:
European Journal of Epidemiology, 2019, v. 34, n. 5, p. 439, doi. 10.1007/s10654-018-0477-6
By:
- Perduca, Vittorio;
- Alexandrov, Ludmil B.;
- Kelly-Irving, Michelle;
- Delpierre, Cyrille;
- Omichessan, Hanane;
- Little, Mark P.;
- Vineis, Paolo;
- Severi, Gianluca
Publication type:
Article
SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair.
Published in:
Oncogene, 2015, v. 34, n. 46, p. 5699, doi. 10.1038/onc.2015.24
By:
- Kanu, N;
- Grönroos, E;
- Martinez, P;
- Burrell, R A;
- Yi Goh, X;
- Bartkova, J;
- Maya-Mendoza, A;
- Mistrík, M;
- Rowan, A J;
- Patel, H;
- Rabinowitz, A;
- East, P;
- Wilson, G;
- Santos, C R;
- McGranahan, N;
- Gulati, S;
- Gerlinger, M;
- Birkbak, N J;
- Joshi, T;
- Alexandrov, L B
Publication type:
Article
Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response.
Published in:
Nature Communications, 2023, v. 14, p. 1, doi. 10.1038/s41467-023-38271-5
By:
- Pagadala, Meghana;
- Sears, Timothy J.;
- Wu, Victoria H.;
- Pérez-Guijarro, Eva;
- Kim, Hyo;
- Castro, Andrea;
- Talwar, James V.;
- Gonzalez-Colin, Cristian;
- Cao, Steven;
- Schmiedel, Benjamin J.;
- Goudarzi, Shervin;
- Kirani, Divya;
- Au, Jessica;
- Zhang, Tongwu;
- Landi, Teresa;
- Salem, Rany M.;
- Morris, Gerald P.;
- Harismendy, Olivier;
- Patel, Sandip Pravin;
- Alexandrov, Ludmil B.
Publication type:
Article
DNA Dynamics Is Likely to Be a Factor in the Genomic Nucleotide Repeats Expansions Related to Diseases.
Published in:
PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019800
By:
- Alexandrov, Boian S.;
- Valtchinov, Vlad I.;
- Alexandrov, Ludmil B.;
- Gelev, Vladimir;
- Dagon, Yossi;
- Bock, Jonathan;
- Kohane, Isaac S.;
- Rasmussen, Kim Ø.;
- Bishop, Alan R.;
- Usheva, Anny
Publication type:
Article
Mammalian Stem Cells Reprogramming in Response to Terahertz Radiation.
Published in:
PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0015806
By:
- Bock, Jonathan;
- Fukuyo, Yayoi;
- Kang, Sona;
- Phipps, M. Lisa;
- Alexandrov, Ludmil B.;
- Rasmussen, Kim Ø.;
- Bishop, Alan R.;
- Rosen, Evan D.;
- Martinez, Jennifer S.;
- Hou-Tong Chen;
- Rodriguez, George;
- Alexandrov, Boian S.;
- Usheva, Anny
Publication type:
Article
Computer Modeling Describes Gravity-Related Adaptation in Cell Cultures.
Published in:
PLoS ONE, 2009, v. 4, n. 12, p. 1, doi. 10.1371/journal.pone.0008332
By:
- Alexandrov, Ludmil B.;
- Alexandrova, Stoyana;
- Usheva, Anny
Publication type:
Article
Hydrogen-Assisted Cracking Fracture Analysis using High-Speed Camera and Delayed Hydrogen Cracking Test.
Published in:
Journal of Failure Analysis & Prevention, 2022, v. 22, n. 1, p. 385, doi. 10.1007/s11668-021-01308-2
By:
- Bourgeois, D.;
- Alexandrov, B.
Publication type:
Article
Selection for resistance to oseltamivir in seasonal and pandemic H1N1 influenza and widespread co-circulation of the lineages.
Published in:
International Journal of Health Geographics, 2010, v. 9, p. 13, doi. 10.1186/1476-072X-9-13
By:
- Janies, Daniel A.;
- Voronkin, Igor O.;
- Studer, Jonathon;
- Hardman, Jori;
- Alexandrov, Boyan B.;
- Treseder, Travis W.;
- Valson, Chandni
Publication type:
Article
Insights into BRCA Cancer Predisposition from Integrated Germline and Somatic Analyses in 7632 Cancers.
Published in:
JNCI Cancer Spectrum, 2019, v. 3, n. 2, p. N.PAG, doi. 10.1093/jncics/pkz028
By:
- Yost, Shawn;
- Ruark, Elise;
- Alexandrov, Ludmil B;
- Rahman, Nazneen
Publication type:
Article
Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-13471-0
By:
- Wang, Zhiyong;
- Wu, Victoria H.;
- Allevato, Michael M.;
- Gilardi, Mara;
- He, Yudou;
- Luis Callejas-Valera, Juan;
- Vitale-Cross, Lynn;
- Martin, Daniel;
- Amornphimoltham, Panomwat;
- Mcdermott, James;
- Yung, Bryan S.;
- Goto, Yusuke;
- Molinolo, Alfredo A.;
- Sharabi, Andrew B.;
- Cohen, Ezra E. W.;
- Chen, Qianming;
- Lyons, J. Guy;
- Alexandrov, Ludmil B.;
- Gutkind, J. Silvio
Publication type:
Article
Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09828-0
By:
- Brinkman, Arie B.;
- Nik-Zainal, Serena;
- Simmer, Femke;
- Rodríguez-González, F. Germán;
- Smid, Marcel;
- Alexandrov, Ludmil B.;
- Butler, Adam;
- Martin, Sancha;
- Davies, Helen;
- Glodzik, Dominik;
- Zou, Xueqing;
- Ramakrishna, Manasa;
- Staaf, Johan;
- Ringnér, Markus;
- Sieuwerts, Anieta;
- Ferrari, Anthony;
- Morganella, Sandro;
- Fleischer, Thomas;
- Kristensen, Vessela;
- Gut, Marta
Publication type:
Article
Dirac Operators on Hermitian Spin Surfaces.
Published in:
Annals of Global Analysis & Geometry, 2000, v. 18, n. 6, p. 529, doi. 10.1023/A:1006601622448
By:
- Alexandrov, B.;
- Ivanov, S.
Publication type:
Article
Preclinical evaluation of avutometinib and defactinib in high‐grade endometrioid endometrial cancer.
Published in:
Cancer Medicine, 2024, v. 13, n. 17, p. 1, doi. 10.1002/cam4.70210
By:
- Hartwich, Tobias Max Philipp;
- Mansolf, Miranda;
- Demirkiran, Cem;
- Greenman, Michelle;
- Bellone, Stefania;
- McNamara, Blair;
- Nandi, Shuvro P.;
- Alexandrov, Ludmil B.;
- Yang‐Hartwich, Yang;
- Coma, Silvia;
- Pachter, Jonathan;
- Santin, Alessandro D.
Publication type:
Article
Tracing Lung Cancer Risk Factors Through Mutational Signatures in Never-Smokers : The Sherlock-Lung Study.
Published in:
American Journal of Epidemiology, 2021, v. 190, n. 6, p. 962, doi. 10.1093/aje/kwaa234
By:
- Landi, Maria Teresa;
- Synnott, Naoise C;
- Rosenbaum, Jennifer;
- Zhang, Tongwu;
- Zhu, Bin;
- Shi, Jianxin;
- Zhao, Wei;
- Kebede, Michael;
- Sang, Jian;
- Choi, Jiyeon;
- Mendoza, Laura;
- Pacheco, Marwil;
- Hicks, Belynda;
- Caporaso, Neil E;
- Abubakar, Mustapha;
- Gordenin, Dmitry A;
- Wedge, David C;
- Alexandrov, Ludmil B;
- Rothman, Nathaniel;
- Lan, Qing
Publication type:
Article
Tracing Lung Cancer Risk Factors Through Mutational Signatures in Never-Smokers : The Sherlock-Lung Study.
Published in:
American Journal of Epidemiology, 2021, v. 190, n. 5, p. 962, doi. 10.1093/aje/kwaa234
By:
- Landi, Maria Teresa;
- Synnott, Naoise C;
- Rosenbaum, Jennifer;
- Zhang, Tongwu;
- Zhu, Bin;
- Shi, Jianxin;
- Zhao, Wei;
- Kebede, Michael;
- Sang, Jian;
- Choi, Jiyeon;
- Mendoza, Laura;
- Pacheco, Marwil;
- Hicks, Belynda;
- Caporaso, Neil E;
- Abubakar, Mustapha;
- Gordenin, Dmitry A;
- Wedge, David C;
- Alexandrov, Ludmil B;
- Rothman, Nathaniel;
- Lan, Qing
Publication type:
Article
Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator.
Published in:
BMC Genomics, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12864-023-09584-y
By:
- Khandekar, Azhar;
- Vangara, Raviteja;
- Barnes, Mark;
- Díaz-Gay, Marcos;
- Abbasi, Ammal;
- Bergstrom, Erik N.;
- Steele, Christopher D.;
- Pillay, Nischalan;
- Alexandrov, Ludmil B.
Publication type:
Article
Generating realistic null hypothesis of cancer mutational landscapes using SigProfilerSimulator.
Published in:
BMC Bioinformatics, 2020, v. 21, n. 1, p. N.PAG, doi. 10.1186/s12859-020-03772-3
By:
- Bergstrom, Erik N.;
- Barnes, Mark;
- Martincorena, Iñigo;
- Alexandrov, Ludmil B.
Publication type:
Article
Binding of Nucleoid-Associated Protein Fis to DNA Is Regulated by DNA Breathing Dynamics.
Published in:
PLoS Computational Biology, 2013, v. 9, n. 1, p. 1, doi. 10.1371/journal.pcbi.1002881
By:
- Nowak-Lovato, Kristy;
- Alexandrov, Ludmil B.;
- Banisadr, Afsheen;
- Bauer, Amy L.;
- Bishop, Alan R.;
- Usheva, Anny;
- Mu, Fangping;
- Hong-Geller, Elizabeth;
- Rasmussen, Kim Ø.;
- Hlavacek, William S.;
- Alexandrov, Boian S.
Publication type:
Article
Understanding mutagenesis through delineation of mutational signatures in human cancer.
Published in:
Carcinogenesis, 2016, v. 37, n. 6, p. 531, doi. 10.1093/carcin/bgw055
By:
- Petljak, Mia;
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Nature Communications, 2017, v. 8, n. 6, p. 15936, doi. 10.1038/ncomms15936
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Publication type:
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Mutational signatures of ionizing radiation in second malignancies.
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Nature Communications, 2016, v. 7, n. 9, p. 12605, doi. 10.1038/ncomms12605
By:
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Publication type:
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Germline MC1R status influences somatic mutation burden in melanoma.
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Nature Communications, 2016, v. 7, n. 7, p. 12064, doi. 10.1038/ncomms12064
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Publication type:
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The topography of mutational processes in breast cancer genomes.
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Nature Communications, 2016, v. 7, n. 5, p. 11383, doi. 10.1038/ncomms11383
By:
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Publication type:
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A mutational signature in gastric cancer suggests therapeutic strategies.
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Nature Communications, 2015, v. 6, n. 10, p. 8683, doi. 10.1038/ncomms9683
By:
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Publication type:
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Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer.
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Nature Communications, 2015, v. 6, n. 4, p. 6605, doi. 10.1038/ncomms7605
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Publication type:
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Heterogeneity of genomic evolution and mutational profiles in multiple myeloma.
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Nature Communications, 2014, v. 5, n. 1, p. 2997, doi. 10.1038/ncomms3997
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