Works matching AU Alessi, Dario

Results: 111
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    Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms.

    Published in:
    Biochemical Journal, 2021, v. 478, n. 3, p. 553, doi. 10.1042/BCJ20200937
    By:
    • Malik, Asad U.;
    • Karapetsas, Athanasios;
    • Nirujogi, Raja S.;
    • Mathea, Sebastian;
    • Chatterjee, Deep;
    • Pal, Prosenjit;
    • Lis, Pawel;
    • Taylor, Matthew;
    • Purlyte, Elena;
    • Gourlay, Robert;
    • Dorward, Mark;
    • Weidlich, Simone;
    • Toth, Rachel;
    • Polinski, Nicole K.;
    • Knapp, Stefan;
    • Tonelli, Francesca;
    • Alessi, Dario R.
    Publication type:
    Article
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    A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.

    Published in:
    Nature Medicine, 2014, v. 20, n. 11, p. 1340, doi. 10.1038/nm.3646
    By:
    • Schönhuber, Nina;
    • Seidler, Barbara;
    • Schuck, Kathleen;
    • Veltkamp, Christian;
    • Schachtler, Christina;
    • Zukowska, Magdalena;
    • Eser, Stefan;
    • Paul, Mariel C;
    • Klein, Sabine;
    • Schneider, Günter;
    • Alessi, Dario R;
    • Varela, Ignacio;
    • Kind, Alexander;
    • Schnieke, Angelika E;
    • Rad, Roland;
    • Schmid, Roland M;
    • Saur, Dieter;
    • Feyerabend, Thorsten B;
    • Rodewald, Hans-Reimer;
    • Eser, Philipp
    Publication type:
    Article
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    LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages.

    Published in:
    EMBO Journal, 2018, v. 37, n. 12, p. 1, doi. 10.15252/embj.201798694
    By:
    • Härtlova, Anetta;
    • Herbst, Susanne;
    • Peltier, Julien;
    • Rodgers, Angela;
    • Bilkei‐Gorzo, Orsolya;
    • Fearns, Antony;
    • Dill, Brian D.;
    • Lee, Heyne;
    • Flynn, Rowan;
    • Cowley, Sally A.;
    • Davies, Paul;
    • Lewis, Patrick A.;
    • Ganley, Ian G.;
    • Martinez, Jennifer;
    • Alessi, Dario R.;
    • Reith, Alastair D.;
    • Trost, Matthias;
    • Gutierrez, Maximiliano G.
    Publication type:
    Article
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    Rab29 activation of the Parkinson's disease-associated LRRK2 kinase.

    Published in:
    EMBO Journal, 2018, v. 37, n. 1, p. 1, doi. 10.15252/embj.201798099
    By:
    • Purlyte, Elena;
    • Dhekne, Herschel S.;
    • Sarhan, Adil R.;
    • Gomez, Rachel;
    • Lis, Pawel;
    • Wightman, Melanie;
    • Martinez, Terina N.;
    • Tonelli, Francesca;
    • Pfeffer, Suzanne R.;
    • Alessi, Dario R.
    Publication type:
    Article
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    Reduced intestinal and renal amino acid transport in PDK1 hypomorphic mice.

    Published in:
    FASEB Journal, 2006, v. 20, n. 13, p. 2214, doi. 10.1096/fj.05-5676com
    By:
    • Rexhepaj, Rexhep;
    • Grahammer, Florian;
    • Völkl, Harald;
    • Remy, Christine;
    • Wagner, Carsten A.;
    • Sandulache, Diana;
    • Artunc, Ferruh;
    • Henke, Guido;
    • Nammi, Srinivas;
    • Capasso, Giovambattista;
    • Alessi, Dario R.;
    • Lang, Florian
    Publication type:
    Article
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    Mutational analysis of the coding regions of the genes encoding protein kinase B-alpha and -beta, phosphoinositide-dependent protein kinase-1, phosphatase targeting to glycogen, protein phosphatase inhibitor-1, and glycogenin: lessons from a search for genetic variability of the insulin-stimulated glycogen synthesis pathway of skeletal muscle in NIDDM patients.

    Published in:
    1999
    By:
    • Hansen, Lars;
    • Fjordvang, Helle;
    • Rasmussen, Soren K.;
    • Vestergaard, Henrik;
    • Echwald, Soren M.;
    • Hansen, Torben;
    • Alessi, Dario;
    • Shenolikar, Shirish;
    • Saltiel, Alan R.;
    • Barbetti, Fabrizio;
    • Pedersen, Oluf;
    • Hansen, L;
    • Fjordvang, H;
    • Rasmussen, S K;
    • Vestergaard, H;
    • Echwald, S M;
    • Hansen, T;
    • Alessi, D;
    • Shenolikar, S;
    • Saltiel, A R
    Publication type:
    journal article
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    Functional kinomics establishes a critical node of volume-sensitive cation-Cl<sup>−</sup> cotransporter regulation in the mammalian brain.

    Published in:
    Scientific Reports, 2016, p. 35986, doi. 10.1038/srep35986
    By:
    • Zhang, Jinwei;
    • Gao, Geng;
    • Begum, Gulnaz;
    • Wang, Jinhua;
    • Khanna, Arjun R.;
    • Shmukler, Boris E.;
    • Daubner, Gerrit M.;
    • de los Heros, Paola;
    • Davies, Paul;
    • Varghese, Joby;
    • Bhuiyan, Mohammad Iqbal H.;
    • Duan, Jinjing;
    • Zhang, Jin;
    • Duran, Daniel;
    • Alper, Seth L.;
    • Sun, Dandan;
    • Elledge, Stephen J.;
    • Alessi, Dario R.;
    • Kahle, Kristopher T.
    Publication type:
    Article
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    Mutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance.

    Published in:
    Molecular & Cellular Biology, 2008, v. 28, n. 10, p. 15, doi. 10.1128/MCB.02032-07
    By:
    • Bayascas, Jose R.;
    • Wullschleger, Stephan;
    • Sakamoto, Kei;
    • García-Martínez, Juan M.;
    • Clacher, Carol;
    • Komander, David;
    • Van Aalten, Daan M. F.;
    • Boini, Krishna M.;
    • Lang, Florian;
    • Lipina, Christopher;
    • Logie, Lisa;
    • Sutherland, Calum;
    • Chudek, John A.;
    • Van Diepen, Janna A.;
    • Voshol, Peter J.;
    • Lucocq, John M.;
    • Alessi, Dario R.
    Publication type:
    Article
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