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Design, synthesis, in vitro biological assessment and molecular modeling insights for novel 3-(naphthalen-1-yl)-4,5-dihydropyrazoles as anticancer agents with potential EGFR inhibitory activity.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-15050-8
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- Article
1,2,4-Triazole-Tethered Indolinones as New Cancer-Fighting Small Molecules Targeting VEGFR-2: Synthesis, Biological Evaluations and Molecular Docking.
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- Pharmaceuticals (14248247), 2024, v. 17, n. 1, p. 81, doi. 10.3390/ph17010081
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- Article
Identification of Novel Cyanopyridones and Pyrido[2,3- D ]Pyrimidines as Anticancer Agents with Dual VEGFR-2/HER-2 Inhibitory Action: Synthesis, Biological Evaluation and Molecular Docking Studies.
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- Pharmaceuticals (14248247), 2022, v. 15, n. 10, p. 1262, doi. 10.3390/ph15101262
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- Article
Design, Synthesis, and Investigation of Cytotoxic Activity of cis -Vinylamide-Linked Combretastatin Analogues as Potential Anticancer Agents.
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- Symmetry (20738994), 2022, v. 14, n. 10, p. N.PAG, doi. 10.3390/sym14102088
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- Article
Design, Synthesis and Cytotoxicity Screening of New Thiazole Derivatives as Potential Anticancer Agents through VEGFR-2 Inhibition.
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- Symmetry (20738994), 2022, v. 14, n. 9, p. 1814, doi. 10.3390/sym14091814
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- Article
Strawberry and Ginger Silver Nanoparticles as Potential Inhibitors for SARS-CoV-2 Assisted by In Silico Modeling and Metabolic Profiling.
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- Antibiotics (2079-6382), 2021, v. 10, n. 7, p. 824, doi. 10.3390/antibiotics10070824
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- Article
The Wound-Healing Potential of Olea europaea L. Cv. Arbequina Leaves Extract: An Integrated In Vitro, In Silico, and In Vivo Investigation.
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- Metabolites (2218-1989), 2022, v. 12, n. 9, p. 791, doi. 10.3390/metabo12090791
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- Article
Novel 3-Substituted 8-Methoxycoumarin Derivatives as Anti-Breast Cancer Drugs.
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- Crystals (2073-4352), 2023, v. 13, n. 7, p. 1037, doi. 10.3390/cryst13071037
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- Article
Unexpected Synthesis, Single-Crystal X-ray Structure, Anticancer Activity, and Molecular Docking Studies of Certain 2–((Imidazole/Benzimidazol–2–yl)thio)–1–arylethanones.
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- Crystals (2073-4352), 2020, v. 10, n. 6, p. 446, doi. 10.3390/cryst10060446
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- Article
New Cytotoxic Cerebrosides from the Red Sea Cucumber Holothuria spinifera Supported by In-Silico Studies.
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- Marine Drugs, 2020, v. 18, n. 8, p. 405, doi. 10.3390/md18080405
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- Article
Thalassosterol, a New Cytotoxic Aromatase Inhibitor Ergosterol Derivative from the Red Sea Seagrass Thalassodendron ciliatum.
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- Marine Drugs, 2020, v. 18, n. 7, p. 354, doi. 10.3390/md18070354
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- Article
Antibacterial, Antioxidant Activity of Ethanolic Plant Extracts of Some Convolvulus Species and Their DART-ToF-MS Profiling.
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- Evidence-based Complementary & Alternative Medicine (eCAM), 2017, v. 2017, p. 1, doi. 10.1155/2017/5694305
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- Article
Design and synthesis of benzo[b]thiophene‐based hybrids as novel antitubercular agents against MDR/XDR Mycobacterium tuberculosis.
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- Archiv der Pharmazie, 2024, v. 357, n. 2, p. 1, doi. 10.1002/ardp.202300529
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- Article
1-Benzyl-5-bromo-3-hydrazonoindolin-2-ones as Novel Anticancer Agents: Synthesis, Biological Evaluation and Molecular Modeling Insights.
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- Molecules, 2023, v. 28, n. 7, p. 3203, doi. 10.3390/molecules28073203
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- Article
Development of Novel Isatin-Tethered Quinolines as Anti-Tubercular Agents against Multi and Extensively Drug-Resistant Mycobacterium tuberculosis.
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- Molecules, 2022, v. 27, n. 24, p. 8807, doi. 10.3390/molecules27248807
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- Article
Synthesis and Biological Activity Screening of Newly Synthesized Trimethoxyphenyl-Based Analogues as Potential Anticancer Agents.
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- Molecules, 2022, v. 27, n. 14, p. N.PAG, doi. 10.3390/molecules27144621
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- Article
Design, Synthesis and Cytotoxic Activity Evaluation of Newly Synthesized Amides-Based TMP Moiety as Potential Anticancer Agents over HepG2 Cells.
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- Molecules, 2022, v. 27, n. 12, p. 3960, doi. 10.3390/molecules27123960
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- Article
Metallic Porphyrazine Networks: Synthesis, as Well as Thermal and Optical Properties for Accelerating the Oxidation of Thiols to Their Disulfides.
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- Metals (2075-4701), 2022, v. 12, n. 9, p. 1523, doi. 10.3390/met12091523
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- Article
New Platinum(IV) and Palladium(II) Transition Metal Complexes of s-Triazine Derivative: Synthesis, Spectral, and Anticancer Agents Studies.
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- BioMed Research International, 2019, p. 1, doi. 10.1155/2019/9835745
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- Article
New Benzoxazole Derivatives as Antiprotozoal Agents: In Silico Studies, Synthesis, and Biological Evaluation.
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- Journal of Chemistry, 2021, p. 1, doi. 10.1155/2021/6631868
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- Article
Bioactive Phytochemicals of Citrus reticulata Seeds—An Example of Waste Product Rich in Healthy Skin Promoting Agents.
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- Antioxidants, 2022, v. 11, n. 5, p. 984, doi. 10.3390/antiox11050984
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- Article
Antioxidant and Wound Healing Potential of Vitis vinifera Seeds Supported by Phytochemical Characterization and Docking Studies.
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- Antioxidants, 2022, v. 11, n. 5, p. 881, doi. 10.3390/antiox11050881
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- Article
Novel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights.
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- Drug Design, Development & Therapy, 2022, v. 16, p. 1457, doi. 10.2147/DDDT.S356988
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- Article
Synthesis, Biological Evaluation and In Silico Studies of Certain Oxindole–Indole Conjugates as Anticancer CDK Inhibitors.
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- Molecules, 2020, v. 25, n. 9, p. 2031, doi. 10.3390/molecules25092031
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- Article
Synthesis of 2-(4,6-Dimethoxy-1,3,5-triazin-2-yloxyimino) Derivatives: Application in Solution Peptide Synthesis.
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- Molecules, 2010, v. 15, n. 12, p. 9403, doi. 10.3390/molecules15129403
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- Article