Found: 40
Select item for more details and to access through your institution.
The SMOC1‐matrisomal proteomics network M42 controls brain homeostasis and modulates toxicity in fly Alzheimer's Disease models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079106
- By:
- Publication type:
- Article
The cytoskeletal protein Plectin regulates Tau‐induced neurotoxicity in Alzheimer's Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078952
- By:
- Publication type:
- Article
Statistical Physics of Fitness Landscapes Finds Risk Genes Specific to Different AD Genetic Backgrounds.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076960
- By:
- Publication type:
- Article
Functional Variants Identify Sex Specific Genes and Pathways in Alzheimer's Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076662
- By:
- Publication type:
- Article
The SMOC1‐matrisomal proteomics network M42 controls brain homeostasis and modulates toxicity in fly Alzheimer's Disease models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079106
- By:
- Publication type:
- Article
The cytoskeletal protein Plectin regulates Tau‐induced neurotoxicity in Alzheimer's Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078952
- By:
- Publication type:
- Article
Statistical Physics of Fitness Landscapes Finds Risk Genes Specific to Different AD Genetic Backgrounds.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076960
- By:
- Publication type:
- Article
Functional Variants Identify Sex Specific Genes and Pathways in Alzheimer's Disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076662
- By:
- Publication type:
- Article
A matrisomal proteomics network modulates tau and amyloid‐beta toxicity in fly AD models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.065708
- By:
- Publication type:
- Article
Systems genetic dissection of Alzheimer's disease brain gene expression networks.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.058716
- By:
- Publication type:
- Article
Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 5, p. 831, doi. 10.1002/alz.12240
- By:
- Publication type:
- Article
Identifying genetic modifiers of APOE in Alzheimer's disease using evolutionary information and regression analyses: Genetics/genetic factors of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043497
- By:
- Publication type:
- Article
P4‐493: IDENTIFYING GENETIC MODIFIERS OF APOE VIA IMPUTATION OF DEVIATION IN EVOLUTIONARY ACTION LOAD IN ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1502, doi. 10.1016/j.jalz.2019.08.039
- By:
- Publication type:
- Article
Downregulation of glial genes involved in synaptic function mitigates Huntington’s disease pathogenesis.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.64564
- By:
- Publication type:
- Article
Inhibition of PIP4Kg ameliorates the pathological effects of mutant huntingtin protein.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.29123.001
- By:
- Publication type:
- Article
TRIM28 regulates the nuclear accumulation and toxicity of both alpha- synuclein and tau.
- Published in:
- eLife, 2016, p. 1, doi. 10.7554/eLife.19809
- By:
- Publication type:
- Article
A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity.
- Published in:
- eLife, 2015, p. 1, doi. 10.7554/eLife.05449
- By:
- Publication type:
- Article
Dual targeting of brain region‐specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1.
- Published in:
- EMBO Journal, 2021, v. 40, n. 7, p. 1, doi. 10.15252/embj.2020106106
- By:
- Publication type:
- Article
Functional variants identify sex-specific genes and pathways in Alzheimer's Disease.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38374-z
- By:
- Publication type:
- Article
TORC1 Inhibition by Rapamycin Promotes Antioxidant Defences in a Drosophila Model of Friedreich’s Ataxia.
- Published in:
- PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0132376
- By:
- Publication type:
- Article
Huntingtin proteolysis releases non-polyQ fragments that cause toxicity through dynamin 1 dysregulation.
- Published in:
- EMBO Journal, 2015, v. 34, n. 17, p. 2255, doi. 10.15252/embj.201490808
- By:
- Publication type:
- Article
Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity.
- Published in:
- PLoS Genetics, 2023, v. 19, n. 5, p. 1, doi. 10.1371/journal.pgen.1010760
- By:
- Publication type:
- Article
Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinson's disease genes.
- Published in:
- Human Molecular Genetics, 2023, v. 32, n. 4, p. 685, doi. 10.1093/hmg/ddac230
- By:
- Publication type:
- Article
Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.
- Published in:
- Science Translational Medicine, 2014, v. 6, n. 268, p. 1, doi. 10.1126/scitranslmed.3010523
- By:
- Publication type:
- Article
Tau polarizes an aging transcriptional signature to excitatory neurons and glia.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.85251
- By:
- Publication type:
- Article
Spinocerebellar Ataxia Type 1 protein Ataxin-1 is signaled to DNA damage by ataxia-telangiectasia mutated kinase.
- Published in:
- Human Molecular Genetics, 2021, v. 30, n. 8, p. 706, doi. 10.1093/hmg/ddab074
- By:
- Publication type:
- Article
Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease.
- Published in:
- Human Molecular Genetics, 2019, v. 28, n. 12, p. 2014, doi. 10.1093/hmg/ddz034
- By:
- Publication type:
- Article
Metal Homeostasis Regulators Suppress FRDA Phenotypes in a Drosophila Model of the Disease.
- Published in:
- PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0159209
- By:
- Publication type:
- Article
Detailed analysis of leucokinin-expressing neurons and their candidate functions in the Drosophila nervous system.
- Published in:
- Cell & Tissue Research, 2010, v. 339, n. 2, p. 321, doi. 10.1007/s00441-009-0890-y
- By:
- Publication type:
- Article
TMEM106B coding variant is protective and deletion detrimental in a mouse model of tauopathy.
- Published in:
- Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-024-02701-5
- By:
- Publication type:
- Article
RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1.
- Published in:
- Nature, 2013, v. 498, n. 7454, p. 325, doi. 10.1038/nature12204
- By:
- Publication type:
- Article
Identification of NUB1 as a suppressor of mutant Huntingtin toxicity via enhanced protein clearance.
- Published in:
- Nature Neuroscience, 2013, v. 16, n. 5, p. 562, doi. 10.1038/nn.3367
- By:
- Publication type:
- Article
A Druggable Genome Screen Identifies Modifiers of α-Synuclein Levels via a Tiered Cross-Species Validation Approach.
- Published in:
- Journal of Neuroscience, 2018, v. 38, n. 43, p. 9286, doi. 10.1523/JNEUROSCI.0254-18.2018
- By:
- Publication type:
- Article
Smaug/SAMD4A Restores Translational Activity of CUGBP1 and Suppresses CUG-Induced Myopathy.
- Published in:
- PLoS Genetics, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.pgen.1003445
- By:
- Publication type:
- Article
A Genome-Scale RNA--Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease.
- Published in:
- PLoS Genetics, 2012, v. 8, n. 11, p. 1, doi. 10.1371/journal.pgen.1003042
- By:
- Publication type:
- Article
dAtaxin-2 Mediates Expanded Ataxin-1-Induced Neurodegeneration in a Drosophila Model of SCA1.
- Published in:
- PLoS Genetics, 2007, v. 3, n. 12, p. e234, doi. 10.1371/journal.pgen.0030234
- By:
- Publication type:
- Article
Comparative analysis of genetic modifiers in Drosophila points to common and distinct mechanisms of pathogenesis among polyglutamine diseases.
- Published in:
- Human Molecular Genetics, 2008, v. 17, n. 3, p. 376, doi. 10.1093/hmg/ddm315
- By:
- Publication type:
- Article
MBNL1 and CUGBP1 modify expanded CUG-induced toxicity in a Drosophila model of myotonic dystrophy type 1.
- Published in:
- Human Molecular Genetics, 2006, v. 15, n. 13, p. 2138, doi. 10.1093/hmg/ddl137
- By:
- Publication type:
- Article
Correction: Inhibition of HIPK3 by AST487 Ameliorates Mutant HTT-Induced Neurotoxicity and Apoptosis via Enhanced Autophagy.
- Published in:
- 2022
- By:
- Publication type:
- Correction Notice
Inhibition of HIPK3 by AST487 Ameliorates Mutant HTT-Induced Neurotoxicity and Apoptosis via Enhanced Autophagy.
- Published in:
- 2022
- By:
- Publication type:
- Letter