Works matching AU Al-Karmalawy, Ahmed A.

Results: 85

Anticholinesterase Activity of Budmunchiamine Alkaloids Revealed by Comparative Chemical Profiling of Two Albizia spp., Molecular Docking and Dynamic Studies.

Published in:

Plants (2223-7747), 2022, v. 11, n. 23, p. 3286, doi. 10.3390/plants11233286

By:

Hussein, Mai E.;
Mohamed, Osama G.;
El-Fishawy, Ahlam M.;
El-Askary, Hesham I.;
Hamed, Ahmed A.;
Abdel-Aziz, Marwa M.;
Alnajjar, Radwan;
Belal, Amany;
Naglah, Ahmed M.;
Almehizia, Abdulrahman A.;
Al-Karmalawy, Ahmed A.;
Tripathi, Ashootosh;
El Senousy, Amira S.

Publication type:

Article

Identification of Antimicrobial Metabolites from the Egyptian Soil-Derived Amycolatopsis keratiniphila Revealed by Untargeted Metabolomics and Molecular Docking.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 5, p. 620, doi. 10.3390/metabo13050620

By:

Hamed, Ahmed A.;
Mohamed, Osama G.;
Aboutabl, Elsayed A.;
Fathy, Fify I.;
Fawzy, Ghada A.;
El-Shiekh, Riham A.;
Al-Karmalawy, Ahmed A.;
Al-Taweel, Areej M.;
Tripathi, Ashootosh;
Elsayed, Tarek R.

Publication type:

Article

Novel Hybrid Indole-Based Caffeic Acid Amide Derivatives as Potent Free Radical Scavenging Agents: Rational Design, Synthesis, Spectroscopic Characterization, In Silico and In Vitro Investigations.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 2, p. 141, doi. 10.3390/metabo13020141

By:

Elkamhawy, Ahmed;
Oh, Na Kyoung;
Gouda, Noha A.;
Abdellattif, Magda H.;
Alshammari, Saud O.;
Abourehab, Mohammed A. S.;
Alshammari, Qamar A.;
Belal, Amany;
Kim, Minkyoung;
Al-Karmalawy, Ahmed A.;
Lee, Kyeong

Publication type:

Article

Investigating the Potential Anti-SARS-CoV-2 and Anti-MERS-CoV Activities of Yellow Necklacepod among Three Selected Medicinal Plants: Extraction, Isolation, Identification, In Vitro, Modes of Action, and Molecular Docking Studies.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 11, p. 1109, doi. 10.3390/metabo12111109

By:

Abd-Alla, Howaida I.;
Kutkat, Omnia;
Sweelam, Heba-tollah M.;
Eldehna, Wagdy M.;
Mostafa, Marwa A.;
Ibrahim, Magda T.;
Moatasim, Yassmin;
GabAllah, Mohamed;
Al-Karmalawy, Ahmed A.

Publication type:

Article

Carvacrol-Loaded Phytosomes for Enhanced Wound Healing: Molecular Docking, Formulation, DoE-Aided Optimization, and in vitro/in vivo Evaluation.

Published in:

International Journal of Nanomedicine, 2023, v. 18, p. 5749, doi. 10.2147/IJN.S421617

By:

Tafish, Ahmed Mowafy;
El-Sherbiny, Mohamed;
Al‐Karmalawy, Ahmed A;
Soliman, Osama Abd El-Azeem;
Saleh, Noha Mohamed

Publication type:

Article

Cytotoxic effects of extracts obtained from plants of the Oleaceae family: bio-guided isolation and molecular docking of new secoiridoids from Jasminum humile.

Published in:

Pharmaceutical Biology, 2022, v. 60, n. 1, p. 1374, doi. 10.1080/13880209.2022.2098346

By:

Mansour, Khaled Ahmed;
Elbermawi, Ahmed;
Al-Karmalawy, Ahmed A.;
Lahloub, Mohamed-Farid;
El-Neketi, Mona

Publication type:

Article

Investigating the effect of polymerase inhibitors on cellular proliferation: Computational studies, cytotoxicity, CDK1 inhibitory potential, and LC‐MS/MS cancer cell entrapment assays.

Published in:

Chemical Biology & Drug Design, 2024, v. 103, n. 3, p. 1, doi. 10.1111/cbdd.14500

By:

Farouk, Faten;
Ibrahim, Ibrahim M.;
Sherif, Salma;
Abdelhamed, Heba Gamal;
Sharaky, Marwa;
Al‐Karmalawy, Ahmed A.

Publication type:

Article

Exploring novel Apalutamide analogues as potential therapeutics for prostate cancer: design, molecular docking investigations and molecular dynamics simulation.

Published in:

Frontiers in Chemistry, 2024, p. 1, doi. 10.3389/fchem.2024.1418975

By:

Gupta, Ajay Kumar;
Vaishnav, Yogesh;
Jain, Sanmati Kumar;
Annadurai, Sivakumar;
Kumar, Neeraj;
Pandrala, Mallesh;
Al-Karmalawy, Ahmed A.

Publication type:

Article

Exploring the sedative properties of natural molecules from hop cones (Humulus lupulus) as promising natural anxiolytics through GABA receptors and the human serotonin transporter.

Published in:

Frontiers in Chemistry, 2024, p. 1, doi. 10.3389/fchem.2024.1425485

By:

Belal, Amany;
Elballal, Mohammed S.;
Al-Karmalawy, Ahmed A.;
Hassan, Ahmed H. E.;
Roh, Eun Joo;
Ghoneim, Mohammed M.;
Ali, Mohamed A. M.;
Obaidullah, Ahmad J.;
Alotaibi, Jawaher M.;
Shaaban, Salwa;
Elanany, Mohamed A.;
Marinho, Emmanuel Silva;
Dimiić, Dusan

Publication type:

Article

LC/MS-Based Metabolomics Reveals Chemical Variations of Two Broccoli Varieties in Relation to Their Anticholinesterase Activity: In vitro and In silico Studies.

Published in:

Plant Foods for Human Nutrition, 2024, v. 79, n. 2, p. 359, doi. 10.1007/s11130-024-01161-2

By:

Ibrahim, Rana M.;
El-Shiekh, Riham A.;
Mohamed, Osama G.;
Al-Karmalawy, Ahmed A.;
Tripathi, Ashootosh;
Abdel-Baki, Passent M.

Publication type:

Article

Investigation of the phytochemical composition, antioxidant, antibacterial, anti-osteoarthritis, and wound healing activities of selected vegetable waste.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38591-y

By:

Salem, Mohamed A.;
Mohamed, Osama G.;
Mosalam, Esraa M.;
Elberri, Aya Ibrahim;
Abdel-Bar, Hend Mohamed;
Hassan, Mariam;
Al-Karmalawy, Ahmed A.;
Tripathi, Ashootosh;
Ezzat, Shahira M.;
Abo Mansour, Hend E.

Publication type:

Article

Investigation of the phytochemical composition, antioxidant, antibacterial, anti-osteoarthritis, and wound healing activities of selected vegetable waste.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38591-y

By:

Salem, Mohamed A.;
Mohamed, Osama G.;
Mosalam, Esraa M.;
Elberri, Aya Ibrahim;
Abdel-Bar, Hend Mohamed;
Hassan, Mariam;
Al-Karmalawy, Ahmed A.;
Tripathi, Ashootosh;
Ezzat, Shahira M.;
Abo Mansour, Hend E.

Publication type:

Article

Ganoderma lucidum extract inhibits Schistosoma mansoni survival in silico and in vitro study.

Published in:

Annals of Parasitology, 2022, v. 68, n. 2, p. 323, doi. 10.17420/ap6802.438

By:

HUSEEIN, Enas Abdelhameed Mahmoud;
SAMIR, Mohamed;
AL-KARMALAWY, Ahmed A.;
HASSAN, Shimaa S.;
EMBAREK MOHAMED, Mona;
MOSTAFA, Fatma Abdel Aziz Mohamed;
MOHARRAM, Ahmed M.;
ALKHALIL, Samia S.;
FARRAG, Haiam Mohamed Mahmoud

Publication type:

Article

A Systematic Review of the Global Intervention for SARS-CoV-2 Combating: From Drugs Repurposing to Molnupiravir Approval.

Published in:

Drug Design, Development & Therapy, 2022, v. 16, p. 685, doi. 10.2147/DDDT.S354841

By:

Ashour, Nada A;
Elmaaty, Ayman Abo;
Sarhan, Amany A;
Elkaeed, Eslam B;
Moussa, Ahmed M;
Erfan, Ibrahim Ali;
Al-Karmalawy, Ahmed A

Publication type:

Article

Design and Synthesis of Benzenesulfonamides Coupled with Piperidine, Morpholine, and N,N‐Dimethylethanamine Moieties as Apoptotic Inducers through VEGFR2 and Topoisomerase II Inhibition.

Published in:

ChemistrySelect, 2023, v. 8, n. 20, p. 1, doi. 10.1002/slct.202301315

By:

Albujuq, Nader R.;
Althumayri, Khalid;
Alharbi, Reem A. K;
Al‐Karmalawy, Ahmed A.;
Nafie, Mohamed S.

Publication type:

Article

Design and synthesis of new spirooxindole candidates and their selenium nanoparticles as potential dual Topo I/II inhibitors, DNA intercalators, and apoptotic inducers.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2242714

By:

El-Kalyoubi, Samar;
Khalifa, Mohamed M.;
Abo-Elfadl, Mahmoud T.;
El-Sayed, Ahmed A.;
Elkamhawy, Ahmed;
Lee, Kyeong;
Al-Karmalawy, Ahmed A.

Publication type:

Article

Novel topoisomerase II/EGFR dual inhibitors: design, synthesis and docking studies of naphtho[2′,3′:4,5]thiazolo[3,2-a]pyrimidine hybrids as potential anticancer agents with apoptosis inducing activity.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2205043

By:

Mourad, Mai A. E.;
Abo Elmaaty, Ayman;
Zaki, Islam;
Mourad, Ahmed A. E.;
Hofni, Amal;
Khodir, Ahmed E.;
Aboubakr, Esam M.;
Elkamhawy, Ahmed;
Roh, Eun Joo;
Al-Karmalawy, Ahmed A.

Publication type:

Article

Development of new TAK-285 derivatives as potent EGFR/HER2 inhibitors possessing antiproliferative effects against 22RV1 and PC3 prostate carcinoma cell lines.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2202358

By:

Son, Seohyun;
Elkamhawy, Ahmed;
Gul, Anam Rana;
Al‐Karmalawy, Ahmed A.;
Alnajjar, Radwan;
Abdeen, Ahmed;
Ibrahim, Samah F.;
Alshammari, Saud O.;
Alshammari, Qamar A.;
Choi, Won Jun;
Park, Tae Jung;
Lee, Kyeong

Publication type:

Article

Design and statistical optimisation of emulsomal nanoparticles for improved anti-SARS-CoV-2 activity of N-(5-nitrothiazol-2-yl)-carboxamido candidates: in vitro and in silico studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2202357

By:

Al-Karmalawy, Ahmed A.;
El-Gamil, Dalia S.;
El-Shesheny, Rabeh;
Sharaky, Marwa;
Alnajjar, Radwan;
Kutkat, Omnia;
Moatasim, Yassmin;
Elagawany, Mohamed;
Al-Rashood, Sara T.;
Binjubair, Faizah A.;
Eldehna, Wagdy M.;
Noreddin, Ayman M.;
Zakaria, Mohamed Y.

Publication type:

Article

Investigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and DNA intercalators: in vitro, molecular docking, molecular dynamics, and SAR studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2171029

By:

Farouk, Faten;
Elmaaty, Ayman Abo;
Elkamhawy, Ahmed;
Tawfik, Haytham O.;
Alnajjar, Radwan;
Abourehab, Mohammed A. S.;
Saleh, Mohamed A.;
Eldehna, Wagdy M.;
Al‐Karmalawy, Ahmed A.

Publication type:

Article

Design and synthesis of novel rigid dibenzo[b,f]azepines through ring closure technique as promising anticancer candidates against leukaemia and acting as selective topoisomerase II inhibitors and DNA intercalators.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2022.2157825

By:

El-Behairy, Mohammed Farrag;
Abd-Allah, Walaa Hamada;
Khalifa, Mohamed M.;
Nafie, Mohamed S.;
Saleh, Mohamed A.;
Abdel-Maksoud, Mohammed S.;
Al-Warhi, Tarfah;
Eldehna, Wagdy M.;
Al‐Karmalawy, Ahmed A.

Publication type:

Article

Biological evaluation, docking studies, and in silico ADME prediction of some pyrimidine and pyridine derivatives as potential EGFRWT and EGFRT790M inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 176, doi. 10.1080/14756366.2022.2135512

By:

Al-Warhi, Tarfah;
Al-Karmalawy, Ahmed A.;
Elmaaty, Ayman Abo;
Alshubramy, Maha A.;
Abdel-Motaal, Marwa;
Majrashi, Taghreed A.;
Asem, Medhat;
Nabil, Ahmed;
Eldehna, Wagdy M.;
Sharaky, Marwa

Publication type:

Article

Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 299, doi. 10.1080/14756366.2021.2007905

By:

Khalifa, Mohamed M.;
Al-Karmalawy, Ahmed A.;
Elkaeed, Eslam B.;
Nafie, Mohamed S.;
Tantawy, Mohamed A.;
Eissa, Ibrahim H.;
Mahdy, Hazem A.

Publication type:

Article

Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 2112, doi. 10.1080/14756366.2022.2105322

By:

Elagawany, Mohamed;
Elmaaty, Ayman Abo;
Mostafa, Ahmed;
Shama, Noura M. Abo;
Santali, Eman Y.;
Elgendy, Bahaa;
Al-Karmalawy, Ahmed A.

Publication type:

Article

Ligand-based design and synthesis of N'-Benzylidene-3,4-dimethoxybenzohydrazide derivatives as potential antimicrobial agents; evaluation by in vitro, in vivo, and in silico approaches with SAR studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 1098, doi. 10.1080/14756366.2022.2063282

By:

Eldin, Rogy R. Ezz;
Saleh, Marwa A.;
Alotaibi, Mohammad Hayal;
Alsuair, Reem K.;
Alzahrani, Yahya A.;
Alshehri, Feras A.;
Mohamed, Amany F.;
Hafez, Shaimaa M.;
Althoqapy, Azza Ali;
Khirala, Seham K.;
Amin, Mona M.;
Yousuf A. F.;
AbdElwahab, Azza H.;
Alesawy, Mohamed S.;
Elmaaty, Ayman Abo;
Al-Karmalawy, Ahmed A.

Publication type:

Article

Discovery of new 1H-pyrazolo[3,4-d]pyrimidine derivatives as anticancer agents targeting EGFRWT and EGFRT790M.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 2283, doi. 10.1080/14756366.2022.2112575

By:

Gaber, Ahmed A.;
Sobhy, Mohamed;
Turky, Abdallah;
Abdulwahab, Hanan Gaber;
Al-Karmalawy, Ahmed A.;
Elhendawy, Mostafa. A.;
Radwan, Mohamed. M.;
Elkaeed, Eslam B.;
Ibrahim, Ibrahim M.;
Elzahabi, Heba S. A.;
Eissa, Ibrahim H.

Publication type:

Article

Design, synthesis and molecular docking of new fused IH-pyrroles, pyrrolo[3,2-d]pyrimidines and pyrrolo[3,2-e][1, 4]diazepine derivatives as potent EGFR/CDK2 inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 1884, doi. 10.1080/14756366.2022.2096019

By:

Belal, Amany;
Gawad, Nagwa M. Abdel;
Mehany, Ahmed B. M.;
Abourehab, Mohammed A. S.;
Elkady, Hazem;
Al-Karmalawy, Ahmed A.;
Ismael, Ahmed S.

Publication type:

Article

Design and synthesis of benzothiazole-based SLC-0111 analogues as new inhibitors for the cancer-associated carbonic anhydrase isoforms IX and XII.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 2635, doi. 10.1080/14756366.2022.2124409

By:

Al-Warhi, Tarfah;
Elbadawi, Mostafa M.;
Bonardi, Alessandro;
Nocentini, Alessio;
Al-Karmalawy, Ahmed A.;
Aljaeed, Nada;
Alotaibi, Ohoud J.;
Abdel-Aziz, Hatem A.;
Supuran, Claudiu T.;
Eldehna, Wagdy M.

Publication type:

Article

Synthesis and Molecular Docking Analysis of New Thiazo-isoindolinedione Hybrids as Potential Inhibitors of the SARS-CoV-2 Main Protease.

Published in:

Oriental Journal of Chemistry, 2023, v. 39, n. 4, p. 913, doi. 10.13005/ojc/390412

By:

SHAABAN, SAAD;
AL-KARMALAWY, AHMED A.;
ALHAMZANI, ABDULRAHMAN G.;
ABOU-KRISHA, MORTAGA M.;
AL-QUDAH, MAHMOUD A.;
YOUSEF, TAREK A.

Publication type:

Article

Innovative Multitarget Organoselenium Hybrids With Apoptotic and Anti‐Inflammatory Properties Acting as JAK1/STAT3 Suppressors.

Published in:

Drug Development Research, 2025, v. 86, n. 2, p. 1, doi. 10.1002/ddr.70075

By:

Shaaban, Saad;
Alabdali, Aya Yaseen Mahmood;
Mousa, Mai H. A.;
Ba‐Ghazal, Hussein;
Al‐Faiyz, Yasair S.;
Elghamry, Ibrahim;
Althikrallah, Hanan A.;
Khatib, Arwa Omar Al;
Alaasar, Mohamed;
Al‐Karmalawy, Ahmed A.

Publication type:

Article

Exploring chromone‐2‐carboxamide derivatives for triple‐negative breast cancer targeting EGFR, FGFR3, and VEGF pathways: Design, synthesis, and preclinical insights.

Published in:

Drug Development Research, 2024, v. 85, n. 5, p. 1, doi. 10.1002/ddr.22228

By:

El‐Gamil, Dalia S.;
Zaky, Mohamed Y.;
Maximous, Patrick M.;
Sharaky, Marwa;
El‐Dessouki, Ahmed M.;
Riad, Noura M.;
Shaaban, Saad;
Abdel‐Halim, Mohammad;
Al‐Karmalawy, Ahmed A.

Publication type:

Article

Design and synthesis of novel tetrabromophthalimide derivatives as potential tubulin inhibitors endowed with apoptotic induction for cancer treatment.

Published in:

Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22197

By:

Abdel‐Motaal, Marwa;
Aldakhili, Dalal A.;
Abo Elmaaty, Ayman;
Sharaky, Marwa;
Mourad, Mai A. E.;
Alzahrani, Abdullah Y. A.;
Mohamed, Nadia A.;
Al‐Karmalawy, Ahmed A.

Publication type:

Article

Design, synthesis, and biological evaluation of thienopyrimidine derivatives as multifunctional agents against Alzheimer's disease.

Published in:

Drug Development Research, 2023, v. 84, n. 5, p. 937, doi. 10.1002/ddr.22064

By:

Eissa, Kholoud I.;
Kamel, Mona M.;
Mohamed, Lamia W.;
Doghish, Ahmed S.;
Alnajjar, Radwan;
Al‐Karmalawy, Ahmed A.;
Kassab, Asmaa E.

Publication type:

Article

Synthesis of New Organoselenium-Based Succinanilic and Maleanilic Derivatives and In Silico Studies as Possible SARS-CoV-2 Main Protease Inhibitors.

Published in:

Inorganics, 2023, v. 11, n. 8, p. 321, doi. 10.3390/inorganics11080321

By:

Shaaban, Saad;
Al-Faiyz, Yasair S.;
Alsulaim, Ghayah M.;
Alaasar, Mohamed;
Amri, Nasser;
Ba-Ghazal, Hussein;
Al-Karmalawy, Ahmed A.;
Abdou, Aly

Publication type:

Article

Exploring the potential of some natural indoles as antiviral agents: quantum chemical analysis, inverse molecular docking, and affinity calculations.

Published in:

Frontiers in Chemistry, 2025, p. 1, doi. 10.3389/fchem.2024.1521298

By:

Belal, Amany;
Abdou, Aly;
Miski, Samar F.;
Ali, Mohamed A. M.;
Ghamry, Heba I.;
Obaidullah, Ahmad J.;
Zaky, Mohamed Y.;
Hassan, Ahmed H. E.;
Roh, Eun Joo;
Al-Karmalawy, Ahmed A.;
Ibrahim, Mona H.

Publication type:

Article

Design and synthesis of novel substituted s‐triazines tethered benzenesulfonamides as potential antimicrobial candidates: Antibiofilm and bacterial protein permeability assessments.

Published in:

Archiv der Pharmazie, 2025, v. 358, n. 3, p. 1, doi. 10.1002/ardp.202400931

By:

Al‐Karmalawy, Ahmed A.;
Tawfik, Haytham O.;
El‐Sayyad, Gharieb S.;
Elmaaty, Ayman Abo;
Abdel‐Fatah, Sobhy S.;
Atiya, Akhtar;
Alzahrani, Abdullah Yahya Abdullah;
Khatib, Arwa Omar Al;
El‐Hamamsy, Mervat H.;
Elsebaie, Heba A.

Publication type:

Article

Pharmacophore‐linked pyrazolo[3,4‐d]pyrimidines as EGFR‐TK inhibitors: Synthesis, anticancer evaluation, pharmacokinetics, and in silico mechanistic studies.

Published in:

Archiv der Pharmazie, 2025, v. 358, n. 3, p. 1, doi. 10.1002/ardp.202100258

By:

Gaber, Ahmed A.;
El‐Morsy, Ahmed M.;
Sherbiny, Farag F.;
Bayoumi, Ashraf H.;
El‐Gamal, Kamal M.;
El‐Adl, Khaled;
Al‐Karmalawy, Ahmed A.;
Ezz Eldin, Rogy R.;
Saleh, Marwa A.;
Abulkhair, Hamada S.

Publication type:

Article

Chalcone‐based benzenesulfonamides as potent and selective inhibitors for human carbonic anhydrase II: Design, synthesis, in vitro, and in silico studies.

Published in:

Archiv der Pharmazie, 2024, v. 357, n. 11, p. 1, doi. 10.1002/ardp.202400069

By:

Lee, Hwa Young;
Elkamhawy, Ahmed;
Al‐Karmalawy, Ahmed A.;
Nada, Hossam;
Giovannuzzi, Simone;
Supuran, Claudiu T.;
Lee, Kyeong

Publication type:

Article

Pharmacophore‐based, rationale design, and efficient synthesis of novel tetrahydrobenzo[b]thiophene candidates as potential dual Topo I/II inhibitors and DNA intercalators.

Published in:

Archiv der Pharmazie, 2024, v. 357, n. 9, p. 1, doi. 10.1002/ardp.202400217

By:

Nofal, Hager R.;
Al‐Karmalawy, Ahmed A.;
Elmaaty, Ayman Abo;
Ismail, Mahmoud F.;
Ali, Ali Khalil;
Abbass, Eslam M.

Publication type:

Article

Design and discovery of new 1,2,4‐triazolo[4,3‐c]quinazolines as potential DNA intercalators and topoisomerase II inhibitors.

Published in:

Archiv der Pharmazie, 2021, v. 354, n. 3, p. 1, doi. 10.1002/ardp.202000237

By:

Alesawy, Mohamed S.;
Al‐Karmalawy, Ahmed A.;
Elkaeed, Eslam B.;
Alswah, Mohamed;
Belal, Ahmed;
Taghour, Mohammed S.;
Eissa, Ibrahim H.

Publication type:

Article

Benzoxazole/benzothiazole‐derived VEGFR‐2 inhibitors: Design, synthesis, molecular docking, and anticancer evaluations.

Published in:

Archiv der Pharmazie, 2019, v. 352, n. 12, p. N.PAG, doi. 10.1002/ardp.201900178

By:

El‐Helby, Abdel‐Ghany A.;
Sakr, Helmy;
Eissa, Ibrahim H.;
Al‐Karmalawy, Ahmed A.;
El‐Adl, Khaled

Publication type:

Article

Design, synthesis, molecular docking, and anticancer activity of benzoxazole derivatives as VEGFR‐2 inhibitors.

Published in:

Archiv der Pharmazie, 2019, v. 352, n. 10, p. N.PAG, doi. 10.1002/ardp.201900113

By:

El‐Helby, Abdel‐Ghany A.;
Sakr, Helmy;
Eissa, Ibrahim H.;
Abulkhair, Hamada;
Al‐Karmalawy, Ahmed A.;
El‐Adl, Khaled

Publication type:

Article

Loperamide potentiates doxorubicin sensitivity in triple‐negative breast cancer cells by targeting MDR1 and JNK and suppressing mTOR and Bcl‐2: In vitro and molecular docking study.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 1, p. 1, doi. 10.1002/jbt.22938

By:

Elia, Shenouda G.;
Al‐Karmalawy, Ahmed A.;
Nasr, Mohamed Y.;
Elshal, Mohamed F.

Publication type:

Article

Cholinesterase Inhibitors from an Endophytic Fungus Aspergillus niveus Fv-er401: Metabolomics, Isolation and Molecular Docking.

Published in:

Molecules, 2023, v. 28, n. 6, p. 2559, doi. 10.3390/molecules28062559

By:

Hamed, Ahmed A.;
El-Shiekh, Riham A.;
Mohamed, Osama G.;
Aboutabl, Elsayed A.;
Fathy, Fify I.;
Fawzy, Ghada A.;
Al-Taweel, Areej M.;
Elsayed, Tarek R.;
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Al-Karmalawy, Ahmed A.

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Molecules, 2022, v. 27, n. 17, p. 5571, doi. 10.3390/molecules27175571

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Belal, Amany;
Elkady, Hazem;
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Amin, Ali H.;
Ghoneim, Mohammed M.;
El-Sherbiny, Mohamed;
Al-Serwi, Rasha Hamed;
Abdou, Mohamed Attia;
Ibrahim, Mona H.;
Mehany, Ahmed B. M.

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Molecules, 2022, v. 27, n. 11, p. 3584, doi. 10.3390/molecules27113584

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Belal, Amany;
Elanany, Mohamed A.;
Santali, Eman Y.;
Al-Karmalawy, Ahmed A.;
Aboelez, Moustafa O.;
Amin, Ali H.;
Abdellattif, Magda H.;
Mehany, Ahmed B. M.;
Elkady, Hazem

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Molecules, 2021, v. 26, n. 21, p. 6559, doi. 10.3390/molecules26216559

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Al-Karmalawy, Ahmed A.;
Farid, Mai M.;
Mostafa, Ahmed;
Ragheb, Alia Y.;
H. Mahmoud, Sara;
Shehata, Mahmoud;
Shama, Noura M. Abo;
GabAllah, Mohamed;
Mostafa-Hedeab, Gomaa;
Marzouk, Mona M.

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Molecules, 2021, v. 26, n. 20, p. 6182, doi. 10.3390/molecules26206182

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Shehata, Mahmoud M.;
Mahmoud, Sara H.;
Tarek, Mohammad;
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Mahmoud, Amal;
Mostafa, Ahmed;
M. Elhefnawi, Mahmoud;
Ali, Mohamed A.

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Pimenta dioica (L.) Merr. Bioactive Constituents Exert Anti-SARS-CoV-2 and Anti-Inflammatory Activities: Molecular Docking and Dynamics, In Vitro, and In Vivo Studies.

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Molecules, 2021, v. 26, n. 19, p. 5844, doi. 10.3390/molecules26195844

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El Gizawy, Heba A.;
Boshra, Sylvia A.;
Mostafa, Ahmed;
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Ismail, Muhammad I.;
Alsfouk, Aisha A.;
Taher, Azza T.;
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Computational Insights on the Potential of Some NSAIDs for Treating COVID-19: Priority Set and Lead Optimization.

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Molecules, 2021, v. 26, n. 12, p. 3772, doi. 10.3390/molecules26123772

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Abo Elmaaty, Ayman;
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Al-Karmalawy, Ahmed A.

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Article