Works by Al-Hashem, Fahaid

Results: 37

Metformin ameliorates ROS-p53-collagen axis of fibrosis and dyslipidemia in type 2 diabetes mellitus-induced left ventricular injury.
Published in:
Archives of Physiology & Biochemistry, 2023, v. 129, n. 3, p. 734, doi. 10.1080/13813455.2020.1869265
By:
- Al-Ani, Bahjat;
- Alzamil, Norah M.;
- Hewett, Peter W.;
- Al-Hashem, Fahaid;
- Bin-Jaliah, Ismaeel;
- Shatoor, Abdullah S.;
- Kamar, Samaa S.;
- Latif, Noha S. Abdel;
- Haidara, Mohamed A.;
- Dawood, Amal F.
Publication type:
Article
Vitamin E protects against the modulation of TNF-α-AMPK axis and inhibits pancreas injury in a rat model of L-arginine-induced acute necrotising pancreatitis.
Published in:
Archives of Physiology & Biochemistry, 2023, v. 129, n. 1, p. 148, doi. 10.1080/13813455.2020.1806330
By:
- Al-Hashem, Fahaid;
- Abd Ellatif, Mohamed;
- ShamsEldeen, Asmaa M.;
- Kamar, Samaa S.;
- Al-Ani, Bahjat;
- Haidara, Mohamed A.
Publication type:
Article
Captopril suppresses hepatic mammalian target of rapamycin cell signaling and biomarkers of inflammation and oxidative stress in thioacetamide-induced hepatotoxicity in rats.
Published in:
Archives of Physiology & Biochemistry, 2021, v. 127, n. 5, p. 414, doi. 10.1080/13813455.2019.1647249
By:
- Al-Hashem, Fahaid;
- Al Humayed, Suliman;
- Haidara, Mohamed A.;
- Abdel Latif, Noha S.;
- Al-Ani, Bahjat
Publication type:
Article
Insulin protects against type 1 diabetes mellitus-induced aortopathy associated with the inhibition of biomarkers of vascular injury in rats.
Published in:
Archives of Physiology & Biochemistry, 2021, v. 127, n. 3, p. 266, doi. 10.1080/13813455.2019.1632900
By:
- Bin-Jaliah, Ismaeel;
- Hewett, Peter W.;
- Al-Hashem, Fahaid;
- Haidara, Mohamed A.;
- Abdel Kader, Dina H.;
- Morsy, M. D.;
- Al-Ani, Bahjat
Publication type:
Article
Ghrelin prevents cardiac cell apoptosis during cardiac remodelling post experimentally induced myocardial infarction in rats via activation of Raf-MEK1/2-ERK1/2 signalling.
Published in:
Archives of Physiology & Biochemistry, 2019, v. 125, n. 2, p. 93, doi. 10.1080/13813455.2018.1437751
By:
- Eid, Refaat A.;
- Alkhateeb, Mahmoud A.;
- Al-Shraim, Mubarak;
- Eleawa, Samy M.;
- Shatoor, Abdullah S.;
- El-Kott, Attalla Farag;
- Zaki, Mohamed Samir Ahmed;
- Shatoor, Khalid A.;
- Bin-Jaliah, Ismaeel;
- Al-Hashem, Fahaid H.
Publication type:
Article
Enhanced hepatic insulin signaling in the livers of high altitude native rats under basal conditions and in the livers of low altitude native rats under insulin stimulation: a mechanistic study.
Published in:
Archives of Physiology & Biochemistry, 2017, v. 123, n. 3, p. 145, doi. 10.1080/13813455.2016.1275701
By:
- Al Dera, Hussain;
- Eleawa, Samy M.;
- Al-Hashem, Fahaid H.;
- Mahzari, Moeber M.;
- Hoja, Ibrahim;
- Al Khateeb, Mahmoud
Publication type:
Article
Insulin and vanadium protect against osteoarthritis development secondary to diabetes mellitus in rats.
Published in:
Archives of Physiology & Biochemistry, 2016, v. 122, n. 3, p. 148, doi. 10.3109/13813455.2016.1159698
By:
- El Karib, Abbas O.;
- Al-Ani, Bahjat;
- Al-Hashem, Fahaid;
- Dallak, Mohammad;
- Bin-Jaliah, Ismaeel;
- El-Gamal, Basiouny;
- Bashir, Salah O.;
- Eid, Refaat A.;
- Haidara, Mohamed A.
Publication type:
Article
Platelet Metabolites as Candidate Biomarkers in Sepsis Diagnosis and Management Using the Proposed Explainable Artificial Intelligence Approach.
Published in:
Journal of Clinical Medicine, 2024, v. 13, n. 17, p. 5002, doi. 10.3390/jcm13175002
By:
- Yagin, Fatma Hilal;
- Aygun, Umran;
- Algarni, Abdulmohsen;
- Colak, Cemil;
- Al-Hashem, Fahaid;
- Ardigò, Luca Paolo
Publication type:
Article
Preventive roles of swimming exercise and pioglitazone treatment on hepatic dysfunction in a rat model of metabolic syndrome.
Published in:
Canadian Journal of Physiology & Pharmacology, 2014, v. 92, n. 2, p. 162, doi. 10.1139/cjpp-2013-0043
By:
- Sakr, Hussein F.;
- Al-Hashem, Fahaid H.;
- El-Naby, Waffaa M. Hassab;
- Alkhateeb, Mahmoud A.;
- Zaki, Mohamed Samir A.;
- Refaey, Hesham M. El;
- Morsy, Mohamed D.
Publication type:
Article
Metabolomics Biomarker Discovery to Optimize Hepatocellular Carcinoma Diagnosis: Methodology Integrating AutoML and Explainable Artificial Intelligence.
Published in:
Diagnostics (2075-4418), 2024, v. 14, n. 18, p. 2049, doi. 10.3390/diagnostics14182049
By:
- Yagin, Fatma Hilal;
- El Shawi, Radwa;
- Algarni, Abdulmohsen;
- Colak, Cemil;
- Al-Hashem, Fahaid;
- Ardigò, Luca Paolo
Publication type:
Article
Combining the Strengths of the Explainable Boosting Machine and Metabolomics Approaches for Biomarker Discovery in Acute Myocardial Infarction.
Published in:
Diagnostics (2075-4418), 2024, v. 14, n. 13, p. 1353, doi. 10.3390/diagnostics14131353
By:
- Arslan, Ahmet Kadir;
- Yagin, Fatma Hilal;
- Algarni, Abdulmohsen;
- AL-Hashem, Fahaid;
- Ardigò, Luca Paolo
Publication type:
Article
Enhancing type 2 diabetes mellitus prediction by integrating metabolomics and tree-based boosting approaches.
Published in:
Frontiers in Endocrinology, 2024, p. 1, doi. 10.3389/fendo.2024.1444282
By:
- Arslan, Ahmet Kadir;
- Yagin, Fatma Hilal;
- Algarni, Abdulmohsen;
- Karaaslan, Erol;
- Al-Hashem, Fahaid;
- Ardigò, Luca Paolo
Publication type:
Article
Identifying iNOS and glycogen as biomarkers for degenerated cerebellar purkinje cells in autism spectrum disorder: Protective effects of erythropoietin and zinc sulfate.
Published in:
PLoS ONE, 2025, v. 20, n. 2, p. 1, doi. 10.1371/journal.pone.0317695
By:
- Al-Garni, Abdulaziz M.;
- Hosny, Sara A.;
- Almasabi, Faris;
- Shati, Ayed A.;
- Alzamil, Norah M.;
- ShamsEldeen, Asmaa M.;
- El-Shafei, Asmaa A.;
- Al-Hashem, Fahaid;
- Zafrah, Hind;
- Maarouf, Amro;
- Al-Ani, Bahjat;
- Bin-Jaliah, Ismaeel;
- Kamar, Samaa S.
Publication type:
Article
Vanillylacetone attenuates cadmium chloride-induced hippocampal damage and memory loss through upregulation of nuclear factor erythroid 2-related factor 2 gene and protein expression.
Published in:
Neural Regeneration Research, 2024, v. 19, n. 12, p. 2750, doi. 10.4103/1673-5374.391300
By:
- AL-Hashem, Fahaid H.;
- Bashir, Salah O.;
- Dawood, Amal F.;
- Aboonq, Moutasem S.;
- Bin-Jaliah, Ismaeel;
- Al-Garni, Abdulaiziz M.;
- Morsy, Mohamed D.
Publication type:
Article
Cardioprotective effect of ghrelin against myocardial infarction-induced left ventricular injury via inhibition of SOCS3 and activation of JAK2/STAT3 signaling.
Published in:
Basic Research in Cardiology, 2018, v. 113, n. 2, p. 0, doi. 10.1007/s00395-018-0671-4
By:
- Eid, Refaat A.;
- Alkhateeb, Mahmoud A.;
- Eleawa, Samy;
- Al-Hashem, Fahaid H.;
- Al-Shraim, Mubarak;
- El-kott, Attalla Farag;
- Zaki, Mohamed Samir Ahmed;
- Dallak, Mohammad A.;
- Aldera, Hussain
Publication type:
Article
Predictive biomarkers of mortality in patients with severe COVID-19 hospitalized in intensive care unit.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1416715
By:
- Ramos dos Santos Medeiros, Sandrelli Meridiana de Fátima;
- Nepomuceno Sousa Lino, Bruna Maria;
- Pietta Perez, Vinícius;
- Soares Sousa, Eduardo Sérgio;
- Helena Campana, Eloiza;
- Miyajima, Fábio;
- Veloso Carvalho-Silva, Wlisses Henrique;
- Dejani, Naiara Naiana;
- de Sousa Fernandes, Matheus Santos;
- Yagin, Fatma Hilal;
- Al-Hashem, Fahaid;
- Elkholi, Safaa M.;
- Alyami, Hanan;
- Oliveira Souto, Fabrício
Publication type:
Article
Biomarker discovery and development of prognostic prediction model using metabolomic panel in breast cancer patients: a hybrid methodology integrating machine learning and explainable artificial intelligence.
Published in:
Frontiers in Molecular Biosciences, 2025, p. 1, doi. 10.3389/fmolb.2024.1426964
By:
- Yagin, Fatma Hilal;
- Gormez, Yasin;
- Al-Hashem, Fahaid;
- Ahmad, Irshad;
- Ahmad, Fuzail;
- Ardigò, Luca Paolo
Publication type:
Article
Increased systemic low grade inflammation in high altitude native rats mediated by adrenergic receptors (669.7).
Published in:
FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.669.7
By:
- AL‐Hashem, Fahaid;
- Assiri, Abdullah;
- Shatoor, Abdullah;
- Elrafaey, Hisham;
- Alessa, Riyad;
- Alkhateeb, Mahmoud
Publication type:
Article
Metformin inhibits mTOR–HIF‐1α axis and profibrogenic and inflammatory biomarkers in thioacetamide‐induced hepatic tissue alterations.
Published in:
Journal of Cellular Physiology, 2019, v. 234, n. 6, p. 9328, doi. 10.1002/jcp.27616
By:
- Al‐Hashem, Fahaid;
- Al‐Humayed, Suliman;
- Amin, Shaimaa N.;
- Kamar, Samaa S.;
- Mansy, Soheir S.;
- Hassan, Sarah;
- Abdel‐Salam, Lubna O.;
- Ellatif, Mohamed Abd;
- Alfaifi, Mohammed;
- Haidara, Mohamed A.;
- Al‐Ani, Bahjat
Publication type:
Article
Resveratrol Pretreatment Ameliorates p53-Bax Axis and Augments the Survival Biomarker B-Cell Lymphoma 2 Modulated by Paracetamol Overdose in a Rat Model of Acute Liver Injury.
Published in:
Pharmacology, 2020, v. 105, n. 1/2, p. 39, doi. 10.1159/000502632
By:
- Al Humayed, Suliman;
- Al-Hashem, Fahaid;
- Haidara, Mohamed A.;
- El Karib, Abbas O.;
- Kamar, Samaa S.;
- Amin, Shaimaa N.;
- Al-Ani, Bahjat
Publication type:
Article
Lipopolysaccharide induces acute lung injury and alveolar haemorrhage in association with the cytokine storm, coagulopathy and AT1R/JAK/STAT augmentation in a rat model that mimics moderate and severe Covid‐19 pathology.
Published in:
Clinical & Experimental Pharmacology & Physiology, 2022, v. 49, n. 4, p. 483, doi. 10.1111/1440-1681.13620
By:
- Al‐Ani, Bahjat;
- ShamsEldeen, Asmaa M.;
- Kamar, Samaa S.;
- Haidara, Mohamed A.;
- Al‐Hashem, Fahaid;
- Alshahrani, Mohammad Y.;
- Al‐Hakami, Ahmed M.;
- Kader, Dina H. Abdel;
- Maarouf, Amro
Publication type:
Article
Acylated ghrelin protects aorta damage post-MI via activation of eNOS and inhibition of angiotensin-converting enzyme induced activation of NAD(P)H-dependent oxidase.
Published in:
Ultrastructural Pathology, 2018, v. 42, n. 5, p. 416, doi. 10.1080/01913123.2018.1526242
By:
- Eid, Refaat A.;
- El-Kott, Attalla Farag;
- Zaki, Mohamed Samir Ahmed;
- Eldeen, Muhammad Alaa;
- Al-Hashem, Fahaid H;
- Alkhateeb, Mahmoud A.;
- Alassiri, Mohammed;
- Aldera, Hussain
Publication type:
Article
Exercise protects against insulin-dependent diabetes-induced osteoarthritis in rats: A scanning electron microscopy study.
Published in:
Ultrastructural Pathology, 2017, v. 41, n. 3, p. 252, doi. 10.1080/01913123.2017.1313346
By:
- Al-Hashem, Fahaid;
- El Karib, Abbas O.;
- Bin-Jaliah, Ismaeel;
- Dallak, Mohammad;
- Sakr, Hussein F.;
- Eid, Refaat A.;
- Zaki, Mohamed Samir A.;
- Al-Shamsi, Mariam;
- Haidara, Mohamed A.;
- Al-Ani, Bahjat
Publication type:
Article
Targeting the Dysregulation of Pancreatic AMPK-iNOS-p53 Axis by Metformin in a Rat Model of L-arginine-Induced Acute Pancreatitis.
Published in:
International Journal of Morphology, 2024, v. 42, n. 6, p. 1679, doi. 10.4067/s0717-95022024000601679
By:
- Alzamil, Norah M.;
- Al-Hashem, Fahaid
Publication type:
Article
Metformin Inhibits ROS/TNF-α Axis-Mediated Chronic Kidney Disease Induced by TAA Independent of Leukocyte Infiltration in Association with the Inhibition of Kidney Injury Biomarkers.
Published in:
International Journal of Morphology, 2023, v. 41, n. 4, p. 1191, doi. 10.4067/s0717-95022023000401191
By:
- Al-Hashem, Fahaid
Publication type:
Article
Suppression of L-Arginine-Induced Acute Necrotizing Pancreatitis in Rats by Metformin Associated with the Inhibition of Myeloperoxidase and Activation of Interleukin-10.
Published in:
International Journal of Morphology, 2021, v. 39, n. 1, p. 102, doi. 10.4067/s0717-95022021000100102
By:
- Al-Hashem, Fahaid
Publication type:
Article
Acetaminophen Induces Alterations to the Renal Tubular Ultrastructure in a Rat Model of Acute Nephrotoxicity Protected by Resveratrol and Quercetin.
Published in:
International Journal of Morphology, 2020, v. 38, n. 3, p. 585, doi. 10.4067/s0717-95022020000300585
By:
- Haidara, Mohamed A.;
- Al-Ani, Bahjat;
- Eid, Refaat A.;
- Mohammed, Muataz E. D.;
- Al-Hashem, Fahaid;
- Dallak, Mohammad
Publication type:
Article
Suppression of Thioacetamide-Induced Hepatic Injury in Rats treatment with Resveratrol: Role of mammalian Target of Rapamycin (mTOR) Cell Signaling.
Published in:
International Journal of Morphology, 2020, v. 38, n. 3, p. 558, doi. 10.4067/s0717-95022020000300558
By:
- Dallak, Mohammad;
- Al-Hashem, Fahaid;
- Haidara, Mohamed A.;
- Abd Ellatif, Mohamed;
- Kamar, Samaa S.;
- ShamsEldeeen, Asmaa M.;
- Dawood, Amal F.;
- Ebrahim, Hasnaa A.;
- Al-Ani, Bahjat
Publication type:
Article
Inhibition of Paracetamol-Induced Acute Kidney Damage in Rats Using a Combination of Resveratrol and Quercetin.
Published in:
International Journal of Morphology, 2019, v. 37, n. 4, p. 1422, doi. 10.4067/s0717-95022019000401422
By:
- Haidara, Mohamed A.;
- Al-Hashem, Fahaid;
- El Karib, Abbas O.;
- Zaki, Mohamed S.;
- Kamar, Samaa S.;
- El-Bidawy, Mahmoud H.;
- Al-Ani, Bahjat
Publication type:
Article
Ghrelin Improves the Fine Structure of Atrial Natriuretic Factor (ANF) Granules and Intercalated Disc Junctions in Experimentally-Induced Myocardial Infarction in Rats.
Published in:
International Journal of Morphology, 2018, v. 36, n. 3, p. 1031, doi. 10.4067/S0717-95022018000301031
By:
- Eid, Refaat A.;
- Ahmed Zaki, Mohamed Samir;
- Alghamdi, Mansour A.;
- Al-Shraim, Mubarak;
- El-kott, Attalla Farag;
- Al-Hashem, Fahaid H.;
- Aldera, Hussain;
- Alkhateeb, Mahmoud A.
Publication type:
Article
Metformin Protects Against Thioacetamide Induced Liver injury in Rats.
Published in:
International Journal of Morphology, 2018, v. 36, n. 3, p. 984, doi. 10.4067/S0717-95022018000300984
By:
- Al-Hashem, Fahaid;
- AlHumayed, Suliman;
- Ellatif, Mohamed Abd;
- Amin, Shaimaa Nasr;
- Kamar, Samaa Samir;
- Al-Ani1, Bahjat;
- Haidara, Mohamed A.
Publication type:
Article
Metformin Pretreatment Ameliorates Diabetic Nephropathy Induced by a Combination of High Fat Diet and Streptozotocin in Rats.
Published in:
International Journal of Morphology, 2018, v. 36, n. 3, p. 969, doi. 10.4067/S0717-95022018000300969
By:
- Dallak, Mohammad;
- Bin-Jaliah, Ismaeel;
- Al-Hashem, Fahaid;
- Kamar, Samaa S.;
- Abdel Kader, Dina H.;
- Amin, Shaimaa N.;
- Haidara, Mohamed A.;
- Al-Ani, Bahjat
Publication type:
Article
The Relationship of Birth Weight, Body Shape and Body Composition at Birth to Altitude in Saudi Arabia.
Published in:
International Journal of Morphology, 2016, v. 34, n. 3, p. 1109, doi. 10.4067/S0717-95022016000300048
By:
- Khalid, Mohammed Elhabib Mohammed;
- Ahmed, Humeda Sweket;
- Osman, Osama Mirghani;
- Al Hashem, Fahaid Hassan
Publication type:
Article
A novel therapeutic combination of vildagliptin and agomelatine alleviates the nephropathy in streptozocin-induced diabetic rats: A structural & biochemical study.
Published in:
Journal of Research in Pharmacy, 2024, v. 28, n. 4, p. 1316, doi. 10.29228/jrp.811
By:
- RAMADAN, OSAMA I.;
- DAMANHORY, AHMED A.;
- ABD-ALLAH, EZZ-ELDIN E.;
- GOMAH, TAMER A.;
- MAHMOUD, MOHAMMED E.;
- ABD-ALLAH, FATMA M.;
- SEWILAM, HAITHAM M.;
- FAYYAD, REDA M. A.;
- DARWISH, MEDHAT M.;
- AL-HASHEM, FAHAID;
- AWAD, MOAAZ M. Y.;
- DIAB, MAHMOUD;
- TAYEE, E. M.;
- ELSEED, MAGDY Y.;
- ABDEL HADY, ALSAYED A.;
- ELSIFY, ABDELHAMID K.
Publication type:
Article
Pilot-Study to Explore Metabolic Signature of Type 2 Diabetes: A Pipeline of Tree-Based Machine Learning and Bioinformatics Techniques for Biomarkers Discovery.
Published in:
Nutrients, 2024, v. 16, n. 10, p. 1537, doi. 10.3390/nu16101537
By:
- Yagin, Fatma Hilal;
- Al-Hashem, Fahaid;
- Ahmad, Irshad;
- Ahmad, Fuzail;
- Alkhateeb, Abedalrhman
Publication type:
Article
Cardiac Adaptive Responses After Hypoxia in an Experimental Model.
Published in:
Angiology, 2010, v. 61, n. 2, p. 145, doi. 10.1177/0003319709352486
By:
- Bin-Jaliah, Ismaeel;
- Ammar, Hania I.;
- Mikhailidis, Dimitri P.;
- Dallak, Mohammed A.;
- Al-Hashem, Fahaid H.;
- Haidara, Mohamed A.;
- Yassin, Hanaa Z.;
- Bahnasi, Abeer A.;
- Rashed, Laila A.;
- Isenovic, Esma R.
Publication type:
Article
The association between physical activity and overweight and obesity in a population of children at high and low altitudes in Southwestern Saudi Arabia.
Published in:
Journal of Family & Community Medicine, 2016, v. 23, n. 2, p. 82, doi. 10.4103/2230-8229.181011
By:
- Ahmed, Humeda S.;
- Khalid, Mohammed E. M.;
- Osman, Osama M.;
- Al-Hashem, Fahaid H.;
- Ballal, Mansour A.
Publication type:
Article