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Dysfunction of the adhesion G protein-coupled receptor latrophilin 1 (ADGRL1/LPHN1) increases the risk of obesity.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01810-7
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- Publication type:
- Article
AMPK and Beyond: The Signaling Network Controlling RabGAPs and Contraction-Mediated Glucose Uptake in Skeletal Muscle.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 3, p. 1910, doi. 10.3390/ijms25031910
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- Publication type:
- Article
Impact of physical fitness and exercise training on subcutaneous adipose tissue beiging markers in humans with and without diabetes and a high‐fat diet‐fed mouse model.
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- Diabetes, Obesity & Metabolism, 2024, v. 26, n. 1, p. 339, doi. 10.1111/dom.15322
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- Publication type:
- Article
Reduced Insulin Clearance Differently Relates to Increased Liver Lipid Content and Worse Glycemic Control in Recent-Onset Type 2 and Type 1 Diabetes.
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- Diabetes Care, 2023, v. 46, n. 12, p. 2232, doi. 10.2337/dc23-1267
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- Article
Overexpressing high levels of human vaspin limits high fat diet-induced obesity and enhances energy expenditure in a transgenic mouse.
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- Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1146454
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- Publication type:
- Article
Chronic stress targets mitochondrial respiratory efficiency in the skeletal muscle of C57BL/6 mice.
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- Cellular & Molecular Life Sciences, 2023, v. 80, n. 4, p. 1, doi. 10.1007/s00018-023-04761-4
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- Article
E96V Mutation in the Kdelr3 Gene Is Associated with Type 2 Diabetes Susceptibility in Obese NZO Mice.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 845, doi. 10.3390/ijms24010845
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- Article
Comparative genomic analyses of multiple backcross mouse populations suggest SGCG as a novel potential obesity-modifier gene.
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- Human Molecular Genetics, 2022, v. 31, n. 23, p. 4019, doi. 10.1093/hmg/ddac150
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- Article
Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling.
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- Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.947169
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- Article
Adaptation of Oxidative Phosphorylation Machinery Compensates for Hepatic Lipotoxicity in Early Stages of MAFLD.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 12, p. 6873, doi. 10.3390/ijms23126873
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- Article
Illumination of the Endogenous Insulin-Regulated TBC1D4 Interactome in Human Skeletal Muscle.
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- 2022
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- Publication type:
- journal article
Identification of Novel Genes Involved in Hyperglycemia in Mice.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 6, p. 3205, doi. 10.3390/ijms23063205
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- Article
Response to Comment on Wendt et al. Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1. Diabetes 2021;70:2796-2809.
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- 2022
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- Publication type:
- letter
Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1.
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- 2021
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- Publication type:
- journal article
Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers.
- Published in:
- Diabetologia, 2021, v. 64, n. 8, p. 1795, doi. 10.1007/s00125-021-05461-z
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- Publication type:
- Article
Alternative exon splicing and differential expression in pancreatic islets reveals candidate genes and pathways implicated in early diabetes development.
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- Mammalian Genome, 2021, v. 32, n. 3, p. 153, doi. 10.1007/s00335-021-09869-1
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- Publication type:
- Article
The RabGAPs TBC1D1 and TBC1D4 Control Uptake of Long-Chain Fatty Acids Into Skeletal Muscle via Fatty Acid Transporter SLC27A4/FATP4.
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- 2020
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- Publication type:
- journal article
Identification of Novel Potential Type 2 Diabetes Genes Mediating β-Cell Loss and Hyperglycemia Using Positional Cloning.
- Published in:
- Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.567191
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- Publication type:
- Article
Role of Patatin-Like Phospholipase Domain-Containing 3 Gene for Hepatic Lipid Content and Insulin Resistance in Diabetes.
- Published in:
- 2020
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- Publication type:
- journal article
Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease.
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- Pflügers Archiv: European Journal of Physiology, 2020, v. 472, n. 9, p. 1273, doi. 10.1007/s00424-020-02417-x
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- Publication type:
- Article
542-P: Association of Cardiac Autonomic Dysfunction with Plasma Lipid Metabolites in Recent-Onset Type 2 Diabetes.
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- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-542-P
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- Publication type:
- Article
164-OR: Role of Small Extracellular Vesicles for the Metabolic Response to Exercising in Insulin Resistant Humans.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-164-OR
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- Publication type:
- Article
1657-P: Patatin-Like Phospholipase Domain-Containing 3 Gene Indirectly Modulates Hepatocellular Lipid Content in Severe Insulin Resistant Diabetes.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1657-P
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- Publication type:
- Article
Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 11, p. 4144, doi. 10.3390/ijms21114144
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- Publication type:
- Article
Rhein, a novel Histone Deacetylase (HDAC) inhibitor with antifibrotic potency in human myocardial fibrosis.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-61886-3
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- Publication type:
- Article
TBC1D4 Is Necessary for Enhancing Muscle Insulin Sensitivity in Response to AICAR and Contraction.
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- 2019
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- Publication type:
- journal article
AMPK and TBC1D1 Regulate Muscle Glucose Uptake After, but Not During, Exercise and Contraction.
- Published in:
- 2019
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- Publication type:
- journal article
275-OR: Higher Liver Fat and Whole-Body Insulin Sensitivity in Newly Diagnosed Type 2 Diabetes Patients with a Variant in Transmembrane 6 Superfamily Member 2 Protein.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-275-OR
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- Publication type:
- Article
A variant of the glucose transporter gene SLC2A2 modifies the glycaemic response to metformin therapy in recently diagnosed type 2 diabetes.
- Published in:
- Diabetologia, 2019, v. 62, n. 2, p. 286, doi. 10.1007/s00125-018-4759-z
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- Publication type:
- Article
Two Novel Candidate Genes for Insulin Secretion Identified by Comparative Genomics of Multiple Backcross Mouse Populations.
- Published in:
- Genetics, 2018, v. 210, n. 4, p. 1527, doi. 10.1534/genetics.118.301578
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- Publication type:
- Article
Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity.
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- Biochemical Journal, 2018, v. 475, n. 18, p. 2969, doi. 10.1042/BCJ20180475
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- Publication type:
- Article
Platelet-RBC interaction mediated by FasL/FasR induces procoagulant activity important for thrombosis.
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- 2018
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- Publication type:
- journal article
Regulation of RabGAPs involved in insulin action.
- Published in:
- Biochemical Society Transactions, 2018, v. 46, n. 3, p. 683, doi. 10.1042/BST20170479
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- Publication type:
- Article
Synthetic cytokine receptors transmit biological signals using arti?cial ligands.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04454-8
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- Publication type:
- Article
Alteration of Liver Peroxisomal and Mitochondrial Functionality in the NZO Mouse Model of Metabolic Syndrome.
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- Proteomics - Clinical Applications, 2018, v. 12, n. 1, p. 1, doi. 10.1002/prca.201700028
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- Publication type:
- Article
Hypoxia in Combination With Muscle Contraction Improves Insulin Action and Glucose Metabolism in Human Skeletal Muscle via the HIF-1α Pathway.
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- 2017
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- Publication type:
- journal article
Association of transketolase polymorphisms with measures of polyneuropathy in patients with recently diagnosed diabetes.
- Published in:
- 2017
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- Publication type:
- journal article
Rab28 is a TBC1D1/TBC1D4 substrate involved in GLUT4 trafficking.
- Published in:
- FEBS Letters, 2017, v. 591, n. 1, p. 88, doi. 10.1002/1873-3468.12509
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- Publication type:
- Article
Lipidomics--Reshaping the Analysis and Perception of Type 2 Diabetes.
- Published in:
- International Journal of Molecular Sciences, 2016, v. 17, n. 11, p. 1841, doi. 10.3390/ijms17111841
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- Publication type:
- Article
Variants in Genes Controlling Oxidative Metabolism Contribute to Lower Hepatic ATP Independent of Liver Fat Content in Type 1 Diabetes.
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- 2016
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- Publication type:
- journal article
Specific Metabolic Profiles and Their Relationship to Insulin Resistance in Recent-Onset Type 1 and Type 2 Diabetes.
- Published in:
- 2016
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- Publication type:
- journal article
Cohort profile: the German Diabetes Study (GDS).
- Published in:
- Cardiovascular Diabetology, 2016, v. 15, p. 1, doi. 10.1186/s12933-016-0374-9
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- Publication type:
- Article
Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing.
- Published in:
- PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0147904
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- Publication type:
- Article
Whole-exome sequencing identifies mutations of TBC1D1 encoding a Rab-GTPase-activating protein in patients with congenital anomalies of the kidneys and urinary tract (CAKUT).
- Published in:
- Human Genetics, 2016, v. 135, n. 1, p. 69, doi. 10.1007/s00439-015-1610-1
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- Publication type:
- Article
Opposing Effects of Reduced Kidney Mass on Liver and Skeletal Muscle Insulin Sensitivity in Obese Mice.
- Published in:
- Diabetes, 2015, v. 64, n. 4, p. 1131, doi. 10.2337/db14-0779
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- Publication type:
- Article
Deletion of both Rab-GTPase-activating proteins TBC14KO and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport. Diabetes 2015;64:746-759.
- Published in:
- 2015
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- Publication type:
- corrected article
Deletion of Both Rab-GTPase-Activating Proteins TBC14KO and TBC1D4 in Mice Eliminates Insulin- and AICAR-Stimulated Glucose Transport.
- Published in:
- Diabetes, 2015, v. 64, n. 3, p. 746, doi. 10.2337/db14-0368
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- Publication type:
- Article
“Deletion of both Rab-GTPase–activating proteins TBC1D1 and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport [corrected].
- Published in:
- 2015
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- Publication type:
- journal article
Pronounced Reduction of Cutaneous Langerhans Cell Density in Recently Diagnosed Type 2 Diabetes.
- Published in:
- Diabetes, 2014, v. 63, n. 3, p. 1148, doi. 10.2337/db13-1444
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- Publication type:
- Article
Activin A impairs insulin action in cardiomyocytes via up-regulation of miR-143.
- Published in:
- Cardiovascular Research, 2013, v. 100, n. 2, p. 201, doi. 10.1093/cvr/cvt173
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- Publication type:
- Article