Works by Akula, Nirmala

Results: 33

Antipsychotic drug use complicates assessment of gene expression changes associated with schizophrenia.

Published in:

Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02392-8

By:

Schulmann, Anton;
Marenco, Stefano;
Vawter, Marquis P.;
Akula, Nirmala;
Limon, Agenor;
Mandal, Ajeet;
Auluck, Pavan K.;
Patel, Yash;
Lipska, Barbara K.;
McMahon, Francis J.

Publication type:

Article

Identity-by-descent filtering as a tool for the identification of disease alleles in exome sequence data from distant relatives.

Published in:

BMC Proceedings, 2011, v. 5, n. Suppl 9, p. 1, doi. 10.1186/1753-6561-5-S9-S76

By:

Akula, Nirmala;
Detera-Wadleigh, Sevilla;
Yin Yao Shugart;
Nalls, Michael;
Steele, Jo;
McMahon, Francis J.

Publication type:

Article

Reply to 'Replication of association of 3p21.1 with susceptibility to bipolar disorder but not major depression'.

Published in:

2011

By:

McMahon, Francis J.;
Akula, Nirmala;
Cichon, Sven;
Detera-Wadleigh, Sevilla D.;
Edenberg, Howard;
Holsboer, Florian;
Nöthen, Markus M.;
Nurnberger, John I.;
Potash, James;
Preisig, Martin;
Rietschel, Marcella;
Schulze, Thomas G.

Publication type:

Letter

Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.

Published in:

Nature Genetics, 2010, v. 42, n. 2, p. 128, doi. 10.1038/ng.523

By:

McMahon, Francis J.;
Akula, Nirmala;
Schulze, Thomas G.;
Muglia, Pierandrea;
Tozzi, Federica;
Detera-Wadleigh, Sevilla D.;
Steele, C. J. M.;
Breuer, René;
Strohmaier, Jana;
Wendland, Jens R.;
Mattheisen, Manuel;
Mühleisen, Thomas W.;
Maier, Wolfgang;
Nöthen, Markus M.;
Cichon, Sven;
Farmer, Anne;
Vincent, John B.;
Holsboer, Florian;
Preisig, Martin;
Rietschel, Marcella

Publication type:

Article

Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin.

Published in:

2004

By:

Cichon, Sven;
Buervenich, Silvia;
Kirov, George;
Akula, Nirmala;
Dimitrova, Albena;
Green, Elaine;
Schumacher, Johannes;
Klopp, Norman;
Becker, Tim;
Ohlraun, Stephanie;
Schulze, Thomas G.;
Tullius, Monja;
Gross, Magdalena M.;
Jones, Lisa;
Krastev, Stefan;
Nikolov, Ivan;
Hamshere, Marian;
Jones, Ian;
Czerski, Piotr M.;
Leszczynska-Rodziewicz, Anna

Publication type:

Letter

Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.

Published in:

2018

By:

Baune, Bernhard T.;
International Consortium on Lithium Genetics (ConLi+Gen);
Amare, Azmeraw T;
Schubert, Klaus Oliver;
Hou, Liping;
Clark, Scott R;
Papiol, Sergi;
Heilbronner, Urs;
Degenhardt, Franziska;
Tekola-Ayele, Fasil;
Hsu, Yi-Hsiang;
Shekhtman, Tatyana;
Adli, Mazda;
Akula, Nirmala;
Akiyama, Kazufumi;
Ardau, Raffaella;
Arias, Bárbara;
Aubry, Jean-Michel;
Backlund, Lena;
Bhattacharjee, Abesh Kumar

Publication type:

journal article

Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder.

Published in:

Translational Psychiatry, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41398-020-00981-5

By:

Lopes, Fabiana L.;
Zhu, Kevin;
Purves, Kirstin L.;
Song, Christopher;
Ahn, Kwangmi;
Hou, Liping;
Akula, Nirmala;
Kassem, Layla;
Bergen, Sarah E.;
Landen, Mikael;
Veras, Andre B.;
Nardi, Antonio E.;
Bipolar Genome Study Consortium (BiGS);
Alliey-Rodriguez, Ney;
Badner, Judith A.;
Berrettini, Wade;
Byerley, William;
Coryell, William;
Craig, David W.;
Edenberg, Howard J.

Publication type:

Article

Correction: Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression.

Published in:

Translational Psychiatry, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41398-019-0442-5

By:

Guo, Wei;
Machado-Vieira, Rodrigo;
Mathew, Sanjay;
Murrough, James W.;
Charney, Dennis S.;
Grunebaum, Matthew;
Oquendo, Maria A.;
Kadriu, Bashkim;
Akula, Nirmala;
Henter, Ioline;
Yuan, Peixiong;
Merikangas, Kathleen;
Drevets, Wayne;
Furey, Maura;
Mann, J. John;
McMahon, Francis J.;
Zarate, Carlos A.;
Shugart, Yin Yao

Publication type:

Article

Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression.

Published in:

Translational Psychiatry, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41398-018-0311-7

By:

Guo, Wei;
Machado-Vieira, Rodrigo;
Mathew, Sanjay;
Murrough, James W.;
Charney, Dennis S.;
Gruenbaum, Matthew;
Oquendo, Maria A.;
Kadriu, Bashkim;
Akula, Nirmala;
Henter, Ioline;
Yuan, Peixiong;
Merikangas, Kathleen;
Drevets, Wayne;
Furey, Maura;
Mann, J. John;
McMahon, Francis J.;
Zarate Jr., Carlos A.;
Shugart, Yin Yao

Publication type:

Article

Schizophrenia risk-associated SNPs affect expression of microRNA 137 host gene: a postmortem study.

Published in:

Human Molecular Genetics, 2024, v. 33, n. 22, p. 1939, doi. 10.1093/hmg/ddae130

By:

Feng, Ningping;
Mandal, Ajeet;
Jambhale, Ananya;
Narnur, Pranav;
Chen, Gang;
Akula, Nirmala;
Kramer, Robin;
Kolachana, Bhaskar;
Xu, Qing;
McMahon, Francis J;
Lipska, Barbara K;
Auluck, Pavan K;
Marenco, Stefano

Publication type:

Article

Cellular Diversity in Human Subgenual Anterior Cingulate and Dorsolateral Prefrontal Cortex by Single-Nucleus RNASequencing.

Published in:

Journal of Neuroscience, 2023, v. 43, n. 19, p. 3582, doi. 10.1523/JNEUROSCI.0830-22.2023

By:

Kim, Billy;
Dowon Kim;
Schulmann, Anton;
Patel, Yash;
Caban-Rivera, Carolina;
Kim, Paul;
Jambhale, Ananya;
Johnson, Kory R.;
Ningping Feng;
Qing Xu;
Sun Jung Kang;
Mandal, Ajeet;
Kelly, Michael;
Akula, Nirmala;
McMahon, Francis J.;
Lipska, Barbara;
Marenco, Stefano;
Auluck, Pavan K.

Publication type:

Article

Defining haplotype blocks and tag single-nucleotide polymorphisms in the human genome.

Published in:

Human Molecular Genetics, 2004, v. 13, n. 3, p. 335, doi. 10.1093/hmg/ddh035

By:

Schulze, Thomas G.;
Zhang, Kui;
Chen, Yu-Sheng;
Akula, Nirmala;
Sun, Fengzhu;
McMahon, Francis J.

Publication type:

Article

Can long-range microsatellite data be used to predict short-range linkage disequilibrium?

Published in:

Human Molecular Genetics, 2002, v. 11, n. 12, p. 1363, doi. 10.1093/hmg/11.12.1363

By:

Schulze, Thomas G.;
Chen, Yu-Sheng;
Akula, Nirmala;
Hennessy, Kathleen;
Badner, Judith A.;
McInnis, Melvin G.;
DePaulo, J. Raymond;
Schumacher, Johannes;
Cichon, Sven;
Propping, Peter;
Maier, Wolfgang;
Rietschel, Marcella;
Nöthen, Markus M.;
McMahon, Francis J.

Publication type:

Article

Association study of 83 candidate genes for bipolar disorder in chromosome 6q selected using an evidence-based prioritization algorithm.

Published in:

American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2013, v. 162B, n. 8, p. 898, doi. 10.1002/ajmg.b.32200

By:

Bigdeli, T. Bernard;
Maher, Brion S.;
Zhao, Zhongming;
Sun, Jingchun;
Medeiros, Helena;
Akula, Nirmala;
McMahon, Francis J.;
Carvalho, Celia;
Ferreira, Susana R.;
Azevedo, Maria H.;
Knowles, James A.;
Pato, Michele T.;
Pato, Carlos N.;
Fanous, Ayman H.

Publication type:

Article

Race, Genetic Ancestry and Response to Antidepressant Treatment for Major Depression.

Published in:

Neuropsychopharmacology, 2013, v. 38, n. 13, p. 2598, doi. 10.1038/npp.2013.166

By:

Murphy, Eleanor;
Hou, Liping;
Maher, Brion S;
Woldehawariat, Girma;
Kassem, Layla;
Akula, Nirmala;
Laje, Gonzalo;
McMahon, Francis J

Publication type:

Article

The antidepressant efficacy of subanesthetic-dose ketamine does not correlate with baseline subcortical volumes in a replication sample with major depressive disorder.

Published in:

2017

By:

Niciu, Mark J.;
Iadarola, Nicolas D.;
Banerjee, Dipavo;
Luckenbaugh, David A.;
Park, Minkyung;
Lener, Marc;
Park, Lawrence;
Ionescu, Dawn F.;
Ballard, Elizabeth D.;
Brutsche, Nancy E.;
Akula, Nirmala;
McMahon, Francis J.;
Machado-Vieira, Rodrigo;
Nugent, Allison C.;
Zarate, Carlos A.;
Zarate, Carlos A Jr

Publication type:

journal article

Molecular genetic overlap in bipolar disorder, schizophrenia, and major depressive disorder.

Published in:

World Journal of Biological Psychiatry, 2014, v. 15, n. 3, p. 200, doi. 10.3109/15622975.2012.662282

By:

Schulze, Thomas G.;
Akula, Nirmala;
Breuer, René;
Steele, Jo;
Nalls, Michael A.;
Singleton, Andrew B.;
Degenhardt, Franziska A.;
Nöthen, Markus M.;
Cichon, Sven;
Rietschel, Marcella;
Mcmahon, Francis J.

Publication type:

Article

Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients.

Published in:

Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01702-2

By:

Schubert, Klaus Oliver;
Thalamuthu, Anbupalam;
Amare, Azmeraw T.;
Frank, Joseph;
Streit, Fabian;
Adl, Mazda;
Akula, Nirmala;
Akiyama, Kazufumi;
Ardau, Raffaella;
Arias, Bárbara;
Aubry, Jean-Michel;
Backlund, Lena;
Bhattacharjee, Abesh Kumar;
Bellivier, Frank;
Benabarre, Antonio;
Bengesser, Susanne;
Biernacka, Joanna M.;
Birner, Armin;
Marie-Claire, Cynthia;
Cearns, Micah

Publication type:

Article

Exome-wide association study of treatment-resistant depression suggests novel treatment targets.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38984-z

By:

Shah, Shrey B.;
Peddada, Teja N.;
Song, Christopher;
Mensah, Maame;
Sung, Heejong;
Yavi, Mani;
Yuan, Peixiong;
Zarate Jr, Carlos A.;
Mickey, Brian J.;
Burmeister, Margit;
Akula, Nirmala;
McMahon, Francis J.

Publication type:

Article

Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder.

Published in:

Frontiers in Psychiatry, 2018, p. 1, doi. 10.3389/fpsyt.2018.00207

By:

Reinbold, Céline S.;
Forstner, Andreas J.;
Hecker, Julian;
Fullerton, Janice M.;
Hoffmann, Per;
Liping Hou;
Heilbronner, Urs;
Degenhardt, Franziska;
Adli, Mazda;
Akiyama, Kazufumi;
Akula, Nirmala;
Ardau, Raffaella;
Arias, Bárbara;
Backlund, Lena;
Benabarre, Antonio;
Bengesser, Susanne;
Bhattacharjee, Abesh K.;
Biernacka, Joanna M.;
Birner, Armin;
Marie-Claire, Cynthia

Publication type:

Article

Prediction of lithium response using genomic data.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80814-z

By:

Stone, William;
Nunes, Abraham;
Akiyama, Kazufumi;
Akula, Nirmala;
Ardau, Raffaella;
Aubry, Jean-Michel;
Backlund, Lena;
Bauer, Michael;
Bellivier, Frank;
Cervantes, Pablo;
Chen, Hsi-Chung;
Chillotti, Caterina;
Cruceanu, Cristiana;
Dayer, Alexandre;
Degenhardt, Franziska;
Del Zompo, Maria;
Forstner, Andreas J.;
Frye, Mark;
Fullerton, Janice M.;
Grigoroiu-Serbanescu, Maria

Publication type:

Article

Independent inheritance of cognition and bipolar disorder in a family sample.

Published in:

American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2025, v. 198, n. 1, p. 1, doi. 10.1002/ajmg.b.33001

By:

D'Amico, Alexander;
Sung, Heejong;
Arbona‐Lampaya, Alejandro;
Freifeld, Ally;
Hosey, Katie;
Garcia, Joshua;
Lacbawan, Ley;
Besançon, Emily;
Kassem, Layla;
Akula, Nirmala;
Knowles, Emma E. M.;
Dickinson, Dwight;
McMahon, Francis J.

Publication type:

Article

Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065636

By:

Manchia, Mirko;
Adli, Mazda;
Akula, Nirmala;
Ardau, Raffaella;
Aubry, Jean-Michel;
Backlund, Lena;
Banzato, Claudio EM.;
Baune, Bernhard T.;
Bellivier, Frank;
Bengesser, Susanne;
Biernacka, Joanna M.;
Brichant-Petitjean, Clara;
Bui, Elise;
Calkin, Cynthia V.;
Cheng, Andrew Tai Ann;
Chillotti, Caterina;
Cichon, Sven;
Clark, Scott;
Czerski, Piotr M.;
Dantas, Clarissa

Publication type:

Article

A Network-Based Approach to Prioritize Results from Genome-Wide Association Studies.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024220

By:

Akula, Nirmala;
Baranova, Ancha;
Seto, Donald;
Solka, Jeffrey;
Nalls, Michael A.;
Singleton, Andrew;
Ferrucci, Luigi;
Tanaka, Toshiko;
Bandinelli, Stefania;
Yoon Shin Cho;
Young Jin Kim;
Jong-Young Lee;
Bok-Ghee Han;
McMahon, Francis J.

Publication type:

Article

Accuracy of CNV Detection from GWAS Data.

Published in:

PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0014511

By:

Dandan Zhang;
Yudong Qian;
Akula, Nirmala;
Alliey-Rodriguez, Ney;
Jinsong Tang;
Gershon, Elliot S.;
Chunyu Liu

Publication type:

Article

HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-97140-7

By:

Le Clerc, Sigrid;
Lombardi, Laura;
Baune, Bernhard T.;
Amare, Azmeraw T.;
Schubert, Klaus Oliver;
Hou, Liping;
Clark, Scott R.;
Papiol, Sergi;
Cearns, Micah;
Heilbronner, Urs;
Degenhardt, Franziska;
Tekola-Ayele, Fasil;
Hsu, Yi-Hsiang;
Shekhtman, Tatyana;
Adli, Mazda;
Akula, Nirmala;
Akiyama, Kazufumi;
Ardau, Raffaella;
Arias, Bárbara;
Aubry, Jean-Michel

Publication type:

Article

Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study.

Published in:

Bipolar Disorders, 2019, v. 21, n. 1, p. 68, doi. 10.1111/bdi.12659

By:

Kalman, Janos L;
Papiol, Sergi;
Forstner, Andreas J;
Heilbronner, Urs;
Degenhardt, Franziska;
Strohmaier, Jana;
Adli, Mazda;
Adorjan, Kristina;
Akula, Nirmala;
Alda, Martin;
Anderson‐Schmidt, Heike;
Andlauer, Till FM;
Anghelescu, Ion‐George;
Ardau, Raffaella;
Arias, Bárbara;
Arolt, Volker;
Aubry, Jean‐Michel;
Backlund, Lena;
Bartholdi, Kim;
Bauer, Michael

Publication type:

Article

Exploring the genetics of lithium response in bipolar disorders.

Published in:

International Journal of Bipolar Disorders, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40345-024-00341-y

By:

Herrera-Rivero, Marisol;
Adli, Mazda;
Akiyama, Kazufumi;
Akula, Nirmala;
Amare, Azmeraw T.;
Ardau, Raffaella;
Arias, Bárbara;
Aubry, Jean-Michel;
Backlund, Lena;
Bellivier, Frank;
Benabarre, Antonio;
Bengesser, Susanne;
Bhattacharjee, Abesh Kumar;
Biernacka, Joanna M.;
Birner, Armin;
Cearns, Micah;
Cervantes, Pablo;
Chen, Hsi-Chung;
Chillotti, Caterina;
Cichon, Sven

Publication type:

Article

Immunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorder.

Published in:

Translational Psychiatry, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41398-024-02865-4

By:

Herrera-Rivero, Marisol;
Gutiérrez-Fragoso, Karina;
Thalamuthu, Anbupalam;
Amare, Azmeraw T.;
Adli, Mazda;
Akiyama, Kazufumi;
Akula, Nirmala;
Ardau, Raffaella;
Arias, Bárbara;
Aubry, Jean-Michel;
Backlund, Lena;
Bellivier, Frank;
Benabarre, Antonio;
Bengesser, Susanne;
Bhattacharjee, Abesh Kumar;
Biernacka, Joanna M.;
Birner, Armin;
Cearns, Micah;
Cervantes, Pablo;
Chen, Hsi-Chung

Publication type:

Article

Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study.

Published in:

Translational Psychiatry, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41398-024-02811-4

By:

Ou, Anna H.;
Rosenthal, Sara B.;
Adli, Mazda;
Akiyama, Kazufumi;
Akula, Nirmala;
Alda, Martin;
Amare, Azmeraw T.;
Ardau, Raffaella;
Arias, Bárbara;
Aubry, Jean-Michel;
Backlund, Lena;
Bauer, Michael;
Baune, Bernhard T.;
Bellivier, Frank;
Benabarre, Antonio;
Bengesser, Susanne;
Bhattacharjee, Abesh Kumar;
Biernacka, Joanna M.;
Cervantes, Pablo;
Chen, Guo-Bo

Publication type:

Article

A resource of induced pluripotent stem cell (iPSC) lines including clinical, genomic, and cellular data from genetically isolated families with mood and psychotic disorders.

Published in:

Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02641-w

By:

Detera-Wadleigh, Sevilla D.;
Kassem, Layla;
Besancon, Emily;
Lopes, Fabiana;
Akula, Nirmala;
Sung, Heejong;
Blattner, Meghan;
Sheridan, Laura;
Lacbawan, Ley Nadine;
Garcia, Joshua;
Gordovez, Francis;
Hosey, Katherine;
Donner, Cassandra;
Salvini, Claudio;
Schulze, Thomas;
Chen, David T. W.;
England, Bryce;
Cross, Joanna;
Jiang, Xueying;
Corona, Winston

Publication type:

Article

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.

Published in:

Human Molecular Genetics, 2016, v. 25, n. 15, p. 3393, doi. 10.1093/hmg/ddw181

By:

Liping Hou;
Bergen, Sarah E.;
Akula, Nirmala;
Jie Song;
Hultman, Christina M.;
Landén, Mikael;
Adli, Mazda;
Alda, Martin;
Ardau, Raffaella;
Arias, Bárbara;
Aubry, Jean-Michel;
Backlund, Lena;
Badner, Judith A.;
Barrett, Thomas B.;
Bauer, Michael;
Baune, Bernhard T.;
Bellivier, Frank;
Benabarre, Antonio;
Bengesser, Susanne;
Berrettini, Wade H.

Publication type:

Article

The International Consortium on Lithium Genetics (ConLiGen): An Initiative by the NIMH and IGSLI to Study the Genetic Basis of Response to Lithium Treatment.

Published in:

Neuropsychobiology, 2010, v. 62, n. 1, p. 72, doi. 10.1159/000314708

By:

Schulze, Thomas G.;
Alda, Martin;
Adli, Mazda;
Akula, Nirmala;
Ardau, Raffaella;
Bui, Elise T.;
Chillotti, Caterina;
Cichon, Sven;
Czerski, Piotr;
Del Zompo, Maria;
Detera-Wadleigh, Sevilla D.;
Grof, Paul;
Gruber, Oliver;
Hashimoto, Ryota;
Hauser, Joanna;
Hoban, Rebecca;
Iwata, Nakao;
Kassem, Layla;
Kato, Tadafumi;
Kittel-Schneider, Sarah

Publication type:

Article