Works by Akinori Akaike

Results: 37

Reduction of Immunoreactivity Against the C-Terminal Region of the Intracellular α-Synuclein by Exogenous α-Synuclein Aggregates: Possibility of Conformational Changes.

Published in:

Journal of Parkinson's Disease, 2016, v. 6, n. 3, p. 569, doi. 10.3233/JPD-160835

By:

Yasuhiko Izumi;
Naoto Kondo;
Ryosuke Takahashi;
Akinori Akaike;
Toshiaki Kume

Publication type:

Article

Therapeutic effect of a novel curcumin derivative GT863 on a mouse model of amyotrophic lateral sclerosis.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2022, v. 23, n. 7/8, p. 489, doi. 10.1080/21678421.2021.2012699

By:

Kato, Hajime;
Sato, Hiroyasu;
Okuda, Michiaki;
Wu, Jun;
Koyama, Shingo;
Izumi, Yasuhiko;
Waku, Tomonori;
Iino, Mitsuyoshi;
Aoki, Masashi;
Arawaka, Shigeki;
Ohta, Yasuyuki;
Ishizawa, Kenichi;
Kawasaki, Kanan;
Urano, Yasuomi;
Miyasaka, Tomohiro;
Noguchi, Noriko;
Kume, Toshiaki;
Akaike, Akinori;
Sugimoto, Hachiro;
Kato, Takeo

Publication type:

Article

C‐Jun N‐terminal kinase inhibition and α‐tocopherol protect midbrain dopaminergic neurons from interferon‐γ/lipopolysaccharide‐induced injury without affecting nitric oxide production.

Published in:

Journal of Neuroscience Research, 2006, v. 83, n. 1, p. 102, doi. 10.1002/jnr.20700

By:

Haruki Shibata;
Hiroshi Katsuki;
Mitsugi Okawara;
Toshiaki Kume;
Akinori Akaike

Publication type:

Article

Iron accelerates the conversion of dopamine‐oxidized intermediates into melanin and provides protection in SH‐SY5Y cells.

Published in:

Journal of Neuroscience Research, 2005, v. 82, n. 1, p. 126, doi. 10.1002/jnr.20595

By:

Yasuhiko Izumi;
Hideyuki Sawada;
Noriyuki Yamamoto;
Toshiaki Kume;
Hiroshi Katsuki;
Shun Shimohama;
Akinori Akaike

Publication type:

Article

Integrin-Associated Protein Promotes Neuronal Differentiation of Neural Stem/Progenitor Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0116741

By:

Fujimura, Kazuhiko;
Niidome, Tetsuhiro;
Shinozuka, Yoriko;
Izumi, Yasuhiko;
Kihara, Takeshi;
Sugimoto, Hachiro;
Akaike, Akinori;
Kume, Toshiaki

Publication type:

Article

Estradiol protects mesencephalic dopaminergic neurons from oxidative stress-induced neuronal death.

Published in:

Journal of Neuroscience Research, 1998, v. 54, n. 5, p. 707, doi. 10.1002/(SICI)1097-4547(19981201)54:5<707::AID-JNR16>3.0.CO;2-T

By:

Sawada, Hideyuki;
Ibi, Masakazu;
Kihara, Takeshi;
Urushitani, Makoto;
Akaike, Akinori;
Shimohama, Shun

Publication type:

Article

Sox21 Promotes Hippocampal Adult Neurogenesis via the Transcriptional Repression of the Hes5 Gene.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 36, p. 12543, doi. 10.1523/JNEUROSCI.5803-11.2012

By:

Matsuda, Satoru;
Kuwako, Ken-ichiro;
Okano, Hirotaka James;
Tsutsumi, Shuichi;
Aburatani, Hiroyuki;
Saga, Yumiko;
Matsuzaki, Yumi;
Akaike, Akinori;
Sugimoto, Hachiro;
Okano, Hideyuki

Publication type:

Article

Integrin α5β1 expression on dopaminergic neurons is involved in dopaminergic neurite outgrowth on striatal neurons.

Published in:

Scientific Reports, 2017, p. 42111, doi. 10.1038/srep42111

By:

Izumi, Yasuhiko;
Wakita, Seiko;
Kanbara, Chisato;
Nakai, Toshie;
Akaike, Akinori;
Kume, Toshiaki

Publication type:

Article

Aminoglutethimide prevents excitotoxic and ischemic injuries in cortical neurons.

Published in:

2006

By:

Shirakawa, Hisashi;
Katsuki, Hiroshi;
Kume, Toshiaki;
Kaneko, Shuji;
Akaike, Akinori

Publication type:

journal article

Inhibition of Ca2+ channel current by μ- and κ-opioid receptors coexpressed in Xenopus oocytes: desensitization dependence on Ca2+ channel α1 subunits.

Published in:

British Journal of Pharmacology, 1997, v. 121, n. 4, p. 806, doi. 10.1038/sj.bjp.0701181

By:

Kaneko, Shuji;
Yada, Nobumichi;
Fukuda, Koichiro;
Kikuwaka, Masanobu;
Akaike, Akinori;
Satoh, Masamichi

Publication type:

Article

Mechanism of selective motor neuronal death after exposure of spinal cord to glutamate: Involvement of glutamate-induced nitric oxide in motor neuron toxicity and nonmotor neuron protection.

Published in:

Annals of Neurology, 1998, v. 44, n. 5, p. 796, doi. 10.1002/ana.410440514

By:

Urushitani, Makoto;
Shimohama, Shun;
Kihara, Takeshi;
Sawada, Hideyuki;
Akaike, Akinori;
Ibi, Masakazu;
Inoue, Ryotaku;
Kitamura, Yoshihisa;
Taniguchi, Takashi;
Kimura, Jun

Publication type:

Article

Dopamine D2-type agonists protect mesencephalic neurons from glutamate neurotoxicity: Mechanisms of neuroprotective treatment against oxidative stress.

Published in:

Annals of Neurology, 1998, v. 44, n. 1, p. 110, doi. 10.1002/ana.410440117

By:

Sawada, Hideyuki;
Ibi, Masakazu;
Kihara, Takeshi;
Urushitani, Makoto;
Akaike, Akinori;
Kimura, Jun;
Shimohama, Shun

Publication type:

Article

Plasminogen potentiates thrombin cytotoxicity and contributes to pathology of intracerebral hemorrhage in rats.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2008, v. 28, n. 3, p. 506, doi. 10.1038/sj.jcbfm.9600547

By:

Fujimoto, Shinji;
Katsuki, Hiroshi;
Ohnishi, Masatoshi;
Takagi, Mikako;
Kume, Toshiaki;
Akaike, Akinori

Publication type:

Article

DJ-1 protects against neurodegeneration caused by focal cerebral ischemia and reperfusion in rats.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2008, v. 28, n. 3, p. 563, doi. 10.1038/sj.jcbfm.9600553

By:

Yanagisawa, Daijiro;
Kitamura, Yoshihisa;
Inden, Masatoshi;
Takata, Kazuyuki;
Taniguchi, Takashi;
Morikawa, Shigehiro;
Morita, Masahito;
Inubushi, Toshiro;
Tooyama, Ikuo;
Taira, Takahiro;
Iguchi-Ariga, Sanae M. M.;
Akaike, Akinori;
Ariga, Hiroyoshi

Publication type:

Article

Mechanisms of Neuroprotective Effects of Nicotine and Acetylcholinesterase Inhibitors: Role of α4 and α7 Receptors in Neuroprotection.

Published in:

Journal of Molecular Neuroscience, 2010, v. 40, n. 1/2, p. 211, doi. 10.1007/s12031-009-9236-1

By:

Akaike, Akinori;
Takada-Takatori, Yuki;
Kume, Toshiaki;
Izumi, Yasuhiko

Publication type:

Article

Dopamine D1/D2 Receptor Interaction.

Published in:

Psychiatry & Clinical Neurosciences, 1991, v. 45, n. 2, p. 507, doi. 10.1111/j.1440-1819.1991.tb02534.x

By:

Sasa, Masashi;
Akaike, Akinori;
Ohno, Yukihiro;
Hara, Mitsuyoshi;
Takaori, Shuji

Publication type:

Article

Nitric oxide-producing microglia mediate thrombin-induced degeneration of dopaminergic neurons in rat midbrain slice culture.

Published in:

Journal of Neurochemistry, 2006, v. 97, n. 5, p. 1232, doi. 10.1111/j.1471-4159.2006.03752.x

By:

Katsuki, Hiroshi;
Okawara, Mitsugi;
Shibata, Haruki;
Kume, Toshiaki;
Akaike, Akinori

Publication type:

Article

Serofendic acid prevents 6-hydroxydopamine-induced nigral neurodegeneration and drug-induced rotational asymmetry in hemi-parkinsonian rats.

Published in:

Journal of Neurochemistry, 2005, v. 95, n. 4, p. 950, doi. 10.1111/j.1471-4159.2005.03413.x

By:

Inden, Masatoshi;
Kitamura, Yoshihisa;
Kondo, Jun-ichi;
Hayashi, Kousuke;
Yanagida, Takashi;
Takata, Kazuyuki;
Tsuchiya, Daiju;
Yanagisawa, Daijiro;
Nishimura, Kaneyasu;
Taniguchi, Takashi;
Shimohama, Shun;
Sugimoto, Hachiro;
Akaike, Akinori

Publication type:

Article

Lipopolysaccharide-induced dopaminergic cell death in rat midbrain slice cultures: role of inducible nitric oxide synthase and protection by indomethacin.

Published in:

Journal of Neurochemistry, 2003, v. 86, n. 5, p. 1201, doi. 10.1046/j.1471-4159.2003.01929.x

By:

Shibata, Haruki;
Katsuki, Hiroshi;
Nishiwaki, Mayumi;
Kume, Toshiaki;
Kaneko, Shuji;
Akaike, Akinori

Publication type:

Article

Depletion of Intracellular Glutathione Increases Susceptibility to Nitric Oxide in Mesencephalic Dopaminergic Neurons.

Published in:

Journal of Neurochemistry, 1999, v. 73, n. 4, p. 1696, doi. 10.1046/j.1471-4159.1999.731696.x

By:

Ibu, Masakazu;
Sawada, Hideyuki;
Kume, Toshiaki;
Katsuki, Hiroshi;
Kaneko, Shuji;
Shimohama, Shun;
Akaike, Akinori

Publication type:

Article

Endogenously Occurring β-Carboline Induces Parkinsonism in Nonprimate Animals: A Possible Causative Protoxin in Idiopathic Parkinson's Disease.

Published in:

Journal of Neurochemistry, 1998, v. 70, n. 2, p. 727, doi. 10.1046/j.1471-4159.1998.70020727.x

By:

Matsubara, Kazuo;
Gonda, Tatsuo;
Sawada, Hideyuki;
Uezono, Takashi;
Kobayashi, Yuta;
Kawamura, Takashi;
Ohtaki, Ko-ichi;
Kimura, Kojiro;
Akaike, Akinori

Publication type:

Article

Biological characterization of ADAM22 variants reveals the importance of a disintegrin domain sequence in cell surface expression.

Published in:

Journal of Receptors & Signal Transduction, 2010, v. 30, n. 2, p. 72, doi. 10.3109/10799891003614790

By:

Sagane, Koji;
Sugimoto, Hachiro;
Akaike, Akinori

Publication type:

Article

Microglia-derived interleukin-6 and leukaemia inhibitory factor promote astrocytic differentiation of neural stem/progenitor cells.

Published in:

European Journal of Neuroscience, 2007, v. 25, n. 3, p. 649, doi. 10.1111/j.1460-9568.2007.05309.x

By:

Nakanishi, Masaya;
Niidome, Tetsuhiro;
Matsuda, Satoru;
Akaike, Akinori;
Kihara, Takeshi;
Sugimoto, Hachiro

Publication type:

Article

Pregnenolone sulphate attenuates AMPA cytotoxicity on rat cortical neurons.

Published in:

European Journal of Neuroscience, 2005, v. 21, n. 9, p. 2329, doi. 10.1111/j.1460-9568.2005.04079.x

By:

Shirakawa, Hisashi;
Katsuki, Hiroshi;
Kume, Toshiaki;
Kaneko, Shuji;
Akaike, Akinori

Publication type:

Article

Retinoic acid receptor stimulation protects midbrain dopaminergic neurons from inflammatory degeneration via BDNF-mediated signaling.

Published in:

Journal of Neurochemistry, 2009, v. 110, n. 2, p. 707, doi. 10.1111/j.1471-4159.2009.06171.x

By:

Katsuki, Hiroshi;
Kurimoto, Emi;
Takemori, Sachiko;
Kurauchi, Yuki;
Hisatsune, Akinori;
Isohama, Yoichiro;
Izumi, Yasuhiko;
Kume, Toshiaki;
Shudo, Koichi;
Akaike, Akinori

Publication type:

Article

Vulnerability to glutamate toxicity of dopaminergic neurons is dependent on endogenous dopamine and MAPK activation.

Published in:

Journal of Neurochemistry, 2009, v. 110, n. 2, p. 745, doi. 10.1111/j.1471-4159.2009.06178.x

By:

Izumi, Yasuhiko;
Yamamoto, Noriyuki;
Matsuo, Takaaki;
Wakita, Seiko;
Takeuchi, Hiroki;
Kume, Toshiaki;
Katsuki, Hiroshi;
Sawada, Hideyuki;
Akaike, Akinori

Publication type:

Article

Amyloid precursor protein promotes endoplasmic reticulum stress-induced cell death via C/EBP homologous protein-mediated pathway.

Published in:

Journal of Neurochemistry, 2009, v. 109, n. 5, p. 1324, doi. 10.1111/j.1471-4159.2009.06067.x

By:

Takahashi, Keita;
Niidome, Tetsuhiro;
Akaike, Akinori;
Kihara, Takeshi;
Sugimoto, Hachiro

Publication type:

Article

Neuroprotective action of donepezil mediated by neuronal nicotinic receptors.

Published in:

Psychogeriatrics, 2006, v. 6, p. S47, doi. 10.1111/j.1479-8301.2006.00171.x

By:

Akaike, Akinori;
Katsuki, Hiroshi;
Kume, Toshiaki;
Takada-Takatori, Yuki

Publication type:

Article

Involvement of apoptosis and cholinergic dysfunction in Alzheimer’s disease.

Published in:

Psychogeriatrics, 2006, v. 6, p. S57, doi. 10.1111/j.1479-8301.2006.00172.x

By:

Tagami, Shinji;
Tsujimoto, Yoshihide;
Akaike, Akinori;
Takashima, Akihiko;
Hasegawa, Masato;
Ishiguro, Koichi;
Shoji, Mikio;
Ito, Nobuo;
Kanemaru, Kazutomi;
Urakami, Katsuya;
Okochi, Masayasu;
Takeda, Masatoshi

Publication type:

Article

Serofendic acid protects from iodinated contrast medium and high glucose probably against superoxide production in LLC-PK1 cells.

Published in:

Clinical & Experimental Nephrology, 2009, v. 13, n. 1, p. 15, doi. 10.1007/s10157-008-0081-2

By:

Kitamura, Osamu;
Uemura, Kazuhide;
Kitamura, Hisayo;
Sugimoto, Hachiro;
Akaike, Akinori;
Ono, Takahiko

Publication type:

Article

E22Δ Mutation in Amyloid β-Protein Promotes β-Sheet Transformation, Radical Production, and Synaptotoxicity, But Not Neurotoxicity.

Published in:

2011

By:

Suzuki, Takayuki;
Murakami, Kazuma;
Izuo, Naotaka;
Kume, Toshiaki;
Akaike, Akinori;
Nagata, Tetsu;
Nishizaki, Tomoyuki;
Tomiyama, Takami;
Takuma, Hiroshi;
Mori, Hiroshi;
Irie, Kazuhiro

Publication type:

Journal Article

E22Δ Mutation in Amyloid β-Protein Promotes β-Sheet Transformation, Radical Production, and Synaptotoxicity, But Not Neurotoxicity.

Published in:

International Journal of Alzheimer's Disease, 2011, v. 2011, p. 1, doi. 10.4061/2011/431320

By:

Suzuki, Takayuki;
Murakami, Kazuma;
Izuo, Naotaka;
Kume, Toshiaki;
Akaike, Akinori;
Nagata, Tetsu;
Nishizaki, Tomoyuki;
Tomiyama, Takami;
Takuma, Hiroshi;
Mori, Hiroshi;
Irie, Kazuhiro

Publication type:

Article

Donepezil modulates amyloid precursor protein endocytosis and reduction by up-regulation of SNX33 expression in primary cortical neurons.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47462-4

By:

Takada-Takatori, Yuki;
Nakagawa, Shota;
Kimata, Riko;
Nao, Yousuke;
Mizukawa, Yumiko;
Urushidani, Tetsuro;
Izumi, Yasuhiko;
Akaike, Akinori;
Tsuchida, Katsuharu;
Kume, Toshiaki

Publication type:

Article

Multiplex Neural Circuit Tracing With G-Deleted Rabies Viral Vectors.

Published in:

Frontiers in Neural Circuits, 2020, v. 13, p. 1, doi. 10.3389/fncir.2019.00077

By:

Suzuki, Toshiaki;
Morimoto, Nao;
Akaike, Akinori;
Osakada, Fumitaka

Publication type:

Article

Endogenous Dopamine Is Involved in the Herbicide Paraquat-Induced Dopaminergic Cell Death.

Published in:

Toxicological Sciences, 2014, v. 139, n. 2, p. 466, doi. 10.1093/toxsci/kfu054

By:

Izumi, Yasuhiko;
Ezumi, Masayuki;
Takada-Takatori, Yuki;
Akaike, Akinori;
Kume, Toshiaki

Publication type:

Article

Glutamate Excitotoxicity Is Involved in Cell Death Caused by Tributyltin in Cultured Rat Cortical Neurons.

Published in:

Toxicological Sciences, 2006, v. 89, n. 1, p. 235, doi. 10.1093/toxsci/kfj007

By:

Nakatsu, Yusuke;
Kotake, Yaichiro;
Komasaka, Kazuya;
Hakozaki, Hiroko;
Taguchi, Ryota;
Kume, Toshiaki;
Akaike, Akinori;
Ohta, Shigeru

Publication type:

Article

Wnt Signaling Promotes Regeneration in the Retina of Adult Mammals.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 15, p. 4210, doi. 10.1523/JNEUROSCI.4193-06.2007

By:

Osakada, Fumitaka;
Ooto, Sotaro;
Akagi, Tadamichi;
Mandai, Michiko;
Akaike, Akinori;
Takahashi, Masayo

Publication type:

Article