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Expression Levels of KMT2C and SLC20A1 Identified by Information-theoretical Analysis Are Powerful Prognostic Biomarkers in Estrogen Receptor-positive Breast Cancer.
Published in:
2017
By:
- Keiko Sato;
- Kazunori Akimoto;
- Sato, Keiko;
- Akimoto, Kazunori
Publication type:
journal article
Short term but highly efficient Cas9 expression mediated by excisional system using adenovirus vector and Cre.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-03803-w
By:
- Nagamoto, Sayaka;
- Agawa, Miyuki;
- Tsuchitani, Emi;
- Akimoto, Kazunori;
- Matsushima, Saki Kondo;
- Kanegae, Yumi
Publication type:
Article
PKCλ regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic Β cells.
Published in:
Journal of Clinical Investigation, 2005, v. 115, n. 1, p. 138, doi. 10.1172/JCI200522232
By:
- Hashimoto, Naoko;
- Kido, Yoshiaki;
- Uchida, Tohru;
- Matsuda, Tomokazu;
- Suzuki, Kazuhisa;
- Inoue, Hiroshi;
- Matsumoto, Michihiro;
- Ogawa, Wataru;
- Maeda, Sakan;
- Fujihara, Hiroaki;
- Ueta, Yoichi;
- Uchiyama, Yasuo;
- Akimoto, Kazunori;
- Ohno, Shigeo;
- Noda, Tetsuo;
- Kasuga, Masato
Publication type:
Article
High Expression of Atypical Protein Kinase C λ/ι in Gastric Cancer as a Prognostic Factor for Recurrence.
Published in:
Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2010, v. 17, n. 1, p. 81, doi. 10.1245/s10434-009-0708-x
By:
- Takagawa, Ryo;
- Akimoto, Kazunori;
- Ichikawa, Yasushi;
- Akiyama, Hirotoshi;
- Kojima, Yasuyuki;
- Ishiguro, Hitoshi;
- Inayama, Yoshiaki;
- Aoki, Ichiro;
- Kunisaki, Chikara;
- Endo, Itaru;
- Nagashima, Yoji;
- Ohno, Shigeo
Publication type:
Article
Regulation of Asymmetric Division by Atypical Protein Kinase C Influences Early Specification of CD8<sup>+</sup> T Lymphocyte Fates.
Published in:
Scientific Reports, 2016, p. 19182, doi. 10.1038/srep19182
By:
- Metz, Patrick J.;
- Lopez, Justine;
- Kim, Stephanie H.;
- Akimoto, Kazunori;
- Ohno, Shigeo;
- Chang, John T.
Publication type:
Article
Association of PSA variability with prostate cancer development using large-scale medical information data: a retrospective cohort study.
Published in:
Genes & Environment, 2023, v. 45, n. 1, p. 1, doi. 10.1186/s41021-023-00280-7
By:
- Maeda-Minami, Ayako;
- Nishikawa, Tomoki;
- Ishikawa, Hideki;
- Mutoh, Michihiro;
- Akimoto, Kazunori;
- Matsuyama, Yutaka;
- Mano, Yasunari;
- Uemura, Hiroji
Publication type:
Article
Loss of aPKCλ in Differentiated Neurons Disrupts the Polarity Complex but Does Not Induce Obvious Neuronal Loss or Disorientation in Mouse Brains.
Published in:
PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0084036
By:
- Yamanaka, Tomoyuki;
- Tosaki, Asako;
- Kurosawa, Masaru;
- Akimoto, Kazunori;
- Hirose, Tomonori;
- Ohno, Shigeo;
- Hattori, Nobutaka;
- Nukina, Nobuyuki
Publication type:
Article
An Essential Role of the Universal Polarity Protein, aPKCλ, on the Maintenance of Podocyte Slit Diaphragms.
Published in:
PLoS ONE, 2009, v. 4, n. 1, p. 1, doi. 10.1371/journal.pone.0004194
By:
- Hirose, Tomonori;
- Satoh, Daisuke;
- Kurihara, Hidetake;
- Kusaka, Chiho;
- Hirose, Hiroko;
- Akimoto, Kazunori;
- Matsusaka, Taiji;
- Ichikawa, Iekuni;
- Noda, Tetsuo;
- Ohno, Shigeo
Publication type:
Article
Dominant negative effect of the truncated p110 subunit of phosphatidylinositol-3 kinase.
Published in:
IUBMB Life, 1996, v. 39, n. 4, p. 721, doi. 10.1080/15216549600201801
By:
- Takayanagi, Junji;
- Kimura, Koutarou;
- Nishioka, Naoya;
- Akimoto, Kazunori;
- Moriya, Shigeharu;
- Ohno, Shigeo;
- Fukui, Yasuhisa
Publication type:
Article
Function of Atypical Protein Kinase C λ in Differentiating Photoreceptors Is Required for Proper Lamination of Mouse Retina.
Published in:
Journal of Neuroscience, 2005, v. 25, n. 44, p. 10290, doi. 10.1523/JNEUROSCI.3657-05.2005
By:
- Koike, Chieko;
- Nishida, Akihiro;
- Akimoto, Kazunori;
- Nakaya, Masa-aki;
- Noda, Tetsuo;
- Ohno, Shigeo;
- Furukawa, Takahisa
Publication type:
Article
High PKCλ expression is required for ALDH1-positive cancer stem cell function and indicates a poor clinical outcome in late-stage breast cancer patients.
Published in:
PLoS ONE, 2020, v. 15, n. 7, p. 1, doi. 10.1371/journal.pone.0235747
By:
- Nozaki, Yuka;
- Motomura, Hitomi;
- Tamori, Shoma;
- Kimura, Yumiko;
- Onaga, Chotaro;
- Kanai, Shotaro;
- Ishihara, Yuka;
- Ozaki, Ayaka;
- Hara, Yasushi;
- Harada, Yohsuke;
- Mano, Yasunari;
- Sato, Tsugumichi;
- Sato, Keiko;
- Sasaki, Kazunori;
- Ishiguro, Hitoshi;
- Ohno, Shigeo;
- Akimoto, Kazunori
Publication type:
Article
Identification of a Gene Expression Signature to Predict the Risk of Early Recurrence and the Degree of Immune Cell Infiltration in Triple-negative Breast Cancer.
Published in:
Cancer Genomics & Proteomics (1109-6535), 2024, v. 21, n. 3, p. 316, doi. 10.21873/cgp.20450
By:
- KEIKO SATO;
- KENTARO MIURA;
- SHOMA TAMORI;
- KAZUNORI AKIMOTO
Publication type:
Article
Protein Kinase C λ/ι (PKCλ/ι): A PKC Isotype Essential for the Development of Multicellular Organisms.
Published in:
Journal of Biochemistry, 2003, v. 133, n. 1, p. 9, doi. 10.1093/jb/mvg018
By:
- Suzuki, Atsushi;
- Akimoto, Kazunori;
- Ohno, Shigeo
Publication type:
Article
Atypical Protein Kinase C Isoform, aPKCλ, Is Essential for Maintaining Hair Follicle Stem Cell Quiescence.
Published in:
Journal of Investigative Dermatology, 2015, v. 135, n. 11, p. 2584, doi. 10.1038/jid.2015.222
By:
- Osada, Shin-Ichi;
- Minematsu, Naoko;
- Oda, Fumino;
- Akimoto, Kazunori;
- Kawana, Seiji;
- Ohno, Shigeo
Publication type:
Article
Dynamic changes in protein components of the tight junction during liver regeneration.
Published in:
Cell & Tissue Research, 2001, v. 305, n. 3, p. 399, doi. 10.1007/s004410100397
By:
- Takaki, Yasuyuki;
- Hirai, Syu-ichi;
- Manabe, Naoyuki;
- Izumi, Yasushi;
- Hirose, Tomonori;
- Nakaya, Masa-aki;
- Suzuki, Atsushi;
- Mizuno, Keiko;
- Akimoto, Kazunori;
- Tsukita, Shoichiro;
- Shuin, Taro;
- Ohno, Shigeo
Publication type:
Article
Transcriptomic and Functional Evidence Show Similarities between Human Amniotic Epithelial Stem Cells and Keratinocytes.
Published in:
Cells (2073-4409), 2022, v. 11, n. 1, p. 70, doi. 10.3390/cells11010070
By:
- Liu, Li-Ping;
- Zheng, Dong-Xu;
- Xu, Zheng-Fang;
- Zhou, Hu-Cheng;
- Wang, Yun-Cong;
- Zhou, Hang;
- Ge, Jian-Yun;
- Sako, Daisuke;
- Li, Mi;
- Akimoto, Kazunori;
- Li, Yu-Mei;
- Zheng, Yun-Wen
Publication type:
Article
Foxp3 and Bcl6 deficiency synergistically induces spontaneous development of atopic dermatitis-like skin disease.
Published in:
International Immunology, 2023, v. 35, n. 9, p. 423, doi. 10.1093/intimm/dxad018
By:
- Tai, Yuki;
- Sakaida, Yuki;
- Kawasaki, Riyo;
- Kanemaru, Kaori;
- Akimoto, Kazunori;
- Brombacher, Frank;
- Ogawa, Shuhei;
- Nakamura, Yoshikazu;
- Harada, Yohsuke
Publication type:
Article
High expression of SLC20A1 is less effective for endocrine therapy and predicts late recurrence in ER-positive breast cancer.
Published in:
PLoS ONE, 2022, v. 17, n. 5, p. 1, doi. 10.1371/journal.pone.0268799
By:
- Onaga, Chotaro;
- Tamori, Shoma;
- Matsuoka, Izumi;
- Ozaki, Ayaka;
- Motomura, Hitomi;
- Nagashima, Yuka;
- Sato, Tsugumichi;
- Sato, Keiko;
- Xiong, Yuyun;
- Sasaki, Kazunori;
- Ohno, Shigeo;
- Akimoto, Kazunori
Publication type:
Article
High SLC20A1 Expression Indicates Poor Prognosis in Prostate Cancer.
Published in:
Cancer Diagnosis & Prognosis, 2023, v. 3, n. 4, p. 439, doi. 10.21873/cdp.10237
By:
- TAIKI OKAMOTO;
- CHOTARO ONAGA;
- IZUMI MATSUOKA;
- AYAKA OZAKI;
- CHIKA MATSUDA;
- TAKAHIRO KASAI;
- YUYUN XIONG;
- YOHSUKE HARADA;
- TSUGUMICHI SATO;
- YOSHIO NAKANO;
- YASUNARI MANO;
- SATORU MIYAZAKI;
- HITOSHI ISHIGURO;
- KEIKO SATO;
- SHOMA TAMORI;
- KAZUNORI SASAKI;
- SHIGEO OHNO;
- KAZUNORI AKIMOTO
Publication type:
Article
Co‑expression of SLC20A1 and ALDH1A3 is associated with poor prognosis, and SLC20A1 is required for the survival of ALDH1‑positive pancreatic cancer stem cells.
Published in:
Oncology Letters, 2024, v. 28, n. 3, p. N.PAG, doi. 10.3892/ol.2024.14558
By:
- Matsuoka, Izumi;
- Kasai, Takahiro;
- Onaga, Chotaro;
- Ozaki, Ayaka;
- Motomura, Hitomi;
- Maemura, Yuki;
- Tada, Yuna;
- Mori, Haruka;
- Hara, Yasushi;
- Xiong, Yuyun;
- Sato, Keiko;
- Tamori, Shoma;
- Sasaki, Kazunori;
- Ohno, Shigeo;
- Akimoto, Kazunori
Publication type:
Article
Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer.
Published in:
Oncology Letters, 2021, v. 22, n. 1, p. N.PAG, doi. 10.3892/ol.2021.12808
By:
- Motomura, Hitomi;
- Ozaki, Ayaka;
- Tamori, Shoma;
- Onaga, Chotaro;
- Nozaki, Yuka;
- Waki, Yuko;
- Takasawa, Ryoko;
- Yoshizawa, Kazumi;
- Mano, Yasunari;
- Sato, Tsugumichi;
- Sasaki, Kazunori;
- Ishiguro, Hitoshi;
- Miyagi, Yohei;
- Nagashima, Yoji;
- Yamamoto, Kouji;
- Sato, Keiko;
- Hanawa, Takehisa;
- Tanuma, Sei-Ichi;
- Ohno, Shigeo;
- Akimoto, Kazunori
Publication type:
Article
Colorectal laterally spreading tumors show characteristic expression of cell polarity factors, including atypical protein kinase C λ/ι, E-cadherin, β-catenin and basement membrane component.
Published in:
Oncology Letters, 2014, v. 8, n. 3, p. 977, doi. 10.3892/ol.2014.2271
By:
- YASUSHI ICHIKAWA;
- YOJI NAGASHIMA;
- KAORI MORIOKA;
- KAZUNORI AKIMOTO;
- YASUYUKI KOJIMA;
- TAKASHI ISHIKAWA;
- AYUMU GOTO;
- NORITOSHI KOBAYASHI;
- KAZUTERU WATANABE;
- MITSUYOSHI OTA;
- SHOICHI FUJII;
- MAYUMI KAWAMATA;
- RYO TAKAGAWA;
- CHIKARA KUNIZAKI;
- HIROKAZU TAKAHASHI;
- ATSUSHI NAKAJIMA;
- SHIN MAEDA;
- HIROSHI SHIMADA;
- YOSHIAKI INAYAMA;
- SHIGEO OHNO
Publication type:
Article
High expression of KIBRA in low atypical protein kinase C-expressing gastric cancer correlates with lymphatic invasion and poor prognosis.
Published in:
Cancer Science, 2013, v. 104, n. 2, p. 259, doi. 10.1111/cas.12066
By:
- Yoshihama, Yohei;
- Izumisawa, Yusuke;
- Akimoto, Kazunori;
- Satoh, Yoshinori;
- Mizushima, Taichi;
- Satoh, Kei;
- Chida, Kazuhiro;
- Takagawa, Ryo;
- Akiyama, Hirotoshi;
- Ichikawa, Yasushi;
- Kunisaki, Chikara;
- Inayama, Yoshiaki;
- Endo, Itaru;
- Nagashima, Yoji;
- Ohno, Shigeo
Publication type:
Article
KIBRA-aPKC Connection: High expression of KIBRA in High Invasion and Poor Prognosis. Overexpression of the aPKC-binding region of KIBRA affects tight junction formation in epithelial cells.
Published in:
Cancer Science, 2013, v. 104, n. 2, p. 00, doi. 10.1111/cas.12069
By:
- Yoshihama, Yohei;
- Izumisawa, Yusuke;
- Akimoto, Kazunori;
- Satoh, Yoshinori;
- Mizushima, Taichi;
- Satoh, Kei;
- Chida, Kazuhiro;
- Takagawa, Ryo;
- Akiyama, Hirotoshi;
- Ichikawa, Yasushi;
- Kunisaki, Chikara;
- Inayama, Yoshiaki;
- Endo, Itaru;
- Nagashima, Yoji;
- Ohno, Shigeo
Publication type:
Article
Coexpression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence.
Published in:
Cancer Science, 2011, v. 102, n. 8, p. 1576, doi. 10.1111/j.1349-7006.2011.01972.x
By:
- Ishiguro, Hitoshi;
- Akimoto, Kazunori;
- Nagashima, Yoji;
- Kagawa, Eriko;
- Sasaki, Takeshi;
- Sano, Jin-yu;
- Takagawa, Ryo;
- Fujinami, Kiyoshi;
- Sasaki, Kazunori;
- Aoki, Ichiro;
- Ohno, Shigeo;
- Kubota, Yoshinobu;
- Uemura, Hiroji
Publication type:
Article

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