Works by Akhtar, Saghir

Results: 73

Epstein-Barr Virus and Human Papillomaviruses Interactions and Their Roles in the Initiation of Epithelial-Mesenchymal Transition and Cancer Progression.

Published in:

Frontiers in Oncology, 2018, p. 1, doi. 10.3389/fonc.2018.00111

By:

Cyprian, Farhan S.;
Al-Farsi, Halema F.;
Vranic, Semir;
Akhtar, Saghir;
Al Moustafa, Ala-Eddin

Publication type:

Article

Epstein--Barr Virus in Gliomas: Cause, Association, or Artifact?

Published in:

Frontiers in Oncology, 2018, p. 1, doi. 10.3389/fonc.2018.00123

By:

Akhtar, Saghir;
Vranic, Semir;
Cyprian, Farhan Sachal;
Al Moustafa, Ala-Eddin

Publication type:

Article

The Role of Epstein--Barr Virus in Cervical Cancer: A Brief Update.

Published in:

Frontiers in Oncology, 2018, p. 1, doi. 10.3389/fonc.2018.00113

By:

Vranic, Semir;
Cyprian, Farhan Sachal;
Akhtar, Saghir;
Al Moustafa, Ala-Eddin

Publication type:

Article

Epidermal growth factor receptor tyrosine kinase-mediated signalling contributes to diabetes-induced vascular dysfunction in the mesenteric bed.

Published in:

British Journal of Pharmacology, 2005, v. 145, n. 6, p. 829, doi. 10.1038/sj.bjp.0706238

By:

Benter, Ibrahim F.;
Yousif, Mariam H. M.;
Griffiths, Sioned M.;
Benboubetra, Mustapha;
Akhtar, Saghir

Publication type:

Article

Chronic treatment with LY294002, an inhibitor of phosphatidylinositol 3-kinase, attenuates ischemia/reperfusion-induced cardiac dysfunction in normotensive and hypertensive diabetic animals.

Published in:

Molecular & Cellular Biochemistry, 2013, v. 373, n. 1/2, p. 259, doi. 10.1007/s11010-012-1497-2

By:

Benter, Ibrahim;
Al-Rashdan, Ibrahim;
Juggi, Jasbir;
Yousif, Mariam;
Akhtar, Saghir

Publication type:

Article

Chronic Treatment with Ang-(1-7) Reverses Abnormal Reactivity in the Corpus Cavernosum and Normalizes Diabetes-Induced Changes in the Protein Levels of ACE, ACE2, ROCK1, ROCK2 and Omega-Hydroxylase in a Rat Model of Type 1 Diabetes.

Published in:

Journal of Diabetes Research, 2014, p. 1, doi. 10.1155/2014/142154

By:

Yousif, Mariam H. M.;
Makki, Batoul;
El-Hashim, Ahmed Z.;
Akhtar, Saghir;
Benter, Ibrahim F.

Publication type:

Article

RU28318, an Aldosterone Antagonist, in Combination with an ACE Inhibitor and Angiotensin Receptor Blocker Attenuates Cardiac Dysfunction in Diabetes.

Published in:

Journal of Diabetes Research, 2013, p. 1, doi. 10.1155/2013/427693

By:

Benter, Ibrahim F.;
Babiker, Fawzi;
Al-Rashdan, Ibrahim;
Yousif, Mariam;
Akhtar, Saghir

Publication type:

Article

Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart.

Published in:

Pharmaceutics, 2022, v. 14, n. 12, p. 2673, doi. 10.3390/pharmaceutics14122673

By:

Akhtar, Saghir;
Babiker, Fawzi;
Akhtar, Usman A.;
Benter, Ibrahim F.

Publication type:

Article

Role of epidermal growth factor receptor (EGFR) in corneal remodelling in diabetes.

Published in:

Acta Ophthalmologica (1755375X), 2009, v. 87, n. 8, p. 881, doi. 10.1111/j.1755-3768.2008.01434.x

By:

Akhtar, Saeed;
Almubrad, Turki;
Bron, Anthony J.;
Yousif, Mariam H. M.;
Benter, Ibrahim F.;
Akhtar, Saghir

Publication type:

Article

Ang-(1-7)/ MAS1 receptor axis inhibits allergic airway inflammation via blockade of Src-mediated EGFR transactivation in a murine model of asthma.

Published in:

PLoS ONE, 2019, v. 14, n. 11, p. 1, doi. 10.1371/journal.pone.0224163

By:

El-Hashim, Ahmed Z.;
Khajah, Maitham A.;
Babyson, Rhema S.;
Renno, Waleed M.;
Ezeamuzie, Charles I.;
Benter, Ibrahim F.;
Akhtar, Saghir

Publication type:

Article

Nonviral delivery of synthetic siRNAs in vivo.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 12, p. 3623, doi. 10.1172/JCI33494

By:

Akhtar, Saghir;
Benter, Ibrahim F.

Publication type:

Article

Diabetes-Induced Renal Vascular Dysfunction Is Normalized by Inhibition of Epidermal Growth Factor Receptor Tyrosine Kinase.

Published in:

Journal of Vascular Research, 2005, v. 42, n. 4, p. 284, doi. 10.1159/000085904

By:

Benter, Ibrahim F.;
Yousif, Mariam H. M.;
Hollins, Andrew J.;
Griffiths, Sioned M.;
Akhtar, Saghir

Publication type:

Article

Angiotensin-(1-7) inhibits allergic inflammation, via the MAS1 receptor, through suppression of ERK1/2- and NF-κB-dependent pathways.

Published in:

2012

By:

El-Hashim AZ;
Renno WM;
Raghupathy R;
Abduo HT;
Akhtar S;
Benter IF;
El-Hashim, Ahmed Z;
Renno, Waleed M;
Raghupathy, Raj;
Abduo, Heba T;
Akhtar, Saghir;
Benter, Ibrahim F

Publication type:

journal article

Angiotensin-(1-7) inhibits allergic inflammation, via the MAS1 receptor, through suppression of ERK1/2- and NF-κB-dependent pathways.

Published in:

British Journal of Pharmacology, 2012, v. 166, n. 6, p. 1964, doi. 10.1111/j.1476-5381.2012.01905.x

By:

El-Hashim, Ahmed Z;
Renno, Waleed M;
Raghupathy, Raj;
Abduo, Heba T;
Akhtar, Saghir;
Benter, Ibrahim F

Publication type:

Article

Angiotensin-(1-7) inhibits epidermal growth factor receptor transactivation via a Mas receptor-dependent pathway.

Published in:

British Journal of Pharmacology, 2012, v. 165, n. 5, p. 1390, doi. 10.1111/j.1476-5381.2011.01613.x

By:

Akhtar, Saghir;
Yousif, Mariam HM;
Dhaunsi, Gursev S;
Chandrasekhar, Bindu;
Al-Farsi, Omama;
Benter, Ibrahim F

Publication type:

Article

The potential role of cyclosporine A in cancer treatment: a comprehensive literature review.

Published in:

Contemporary Oncology / Współczesna Onkologia, 2024, v. 28, n. 4, p. 271, doi. 10.5114/wo.2024.147009

By:

Fojnica, Adnan;
Gromilic, Zehra;
Ali Mohamed, Youssef Alaaeldin;
Akhtar, Saghir;
Vranic, Semir

Publication type:

Article

The cardiac toxicity of PAMAM dendrimer drug delivery systems can be attenuated with the adjunct use of cardioprotective agents.

Published in:

Biomolecules & Biomedicine, 2025, v. 25, n. 4, p. 914, doi. 10.17305/bb.2024.10735

By:

Akhtar, Saghir;
Babiker, Fawzi;
Al-Kouh, Aisha;
Benter, Ibrahim F.

Publication type:

Article

Diabetes-induced peripheral neuropathy: Is prescribing physical exercise the answer?

Published in:

Biomolecules & Biomedicine, 2024, v. 24, n. 3, p. 436, doi. 10.17305/bb.2023.10188

By:

Akhtar, Saghir

Publication type:

Article

COVID-19 and Alzheimer's disease: Impact of lockdown and other restrictive measures during the COVID-19 pandemic.

Published in:

Biomolecules & Biomedicine, 2024, v. 24, n. 2, p. 219, doi. 10.17305/bb.2023.9680

By:

Nawaz, Ahmed Daniyal;
Haider, Mohammad Zulqurnain;
Akhtar, Saghir

Publication type:

Article

The Role of Epidermal Growth Factor Receptor Family of Receptor Tyrosine Kinases in Mediating Diabetes-Induced Cardiovascular Complications.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.701390

By:

Shraim, Bara A.;
Moursi, Moaz O.;
Benter, Ibrahim F.;
Habib, Abdella M.;
Akhtar, Saghir

Publication type:

Article

Confidence in Prescribing Practices: Perspectives of Senior Medical Students and Recent Graduates at Qatar University.

Published in:

Advances in Medical Education & Practice, 2024, v. 15, p. 1325, doi. 10.2147/AMEP.S476352

By:

Allouch, Soumaya;
Ali, Raja Mahamade;
Ahmed, Mohammed Seed;
Akhtar, Saghir;
Awaisu, Ahmed;
Bidmos, Mubarak

Publication type:

Article

Microarray Analysis of the Toxicogenomics and the Genotoxic Potential of a Cationic Lipid-Based Gene Delivery Nanosystem in Human Alveolar Epithelial A549 Cells.

Published in:

Toxicology Mechanisms & Methods, 2008, v. 18, n. 4, p. 369, doi. 10.1080/15376510801891286

By:

Omidi, Yadollah;
Barar, Jaleh;
Heidari, Hamid Reza;
Ahmadian, Somaieh;
Yazdi, Hossein Ahmadpour;
Akhtar, Saghir

Publication type:

Article

Site-Specific Administration of Antisense Oligonucleotides using Biodegradable Polymer Microspheres Provides Sustained Delivery and Improved Subcellular Biodistribution in the Neostriatum of the Rat Brain.

Published in:

Journal of Drug Targeting, 2000, v. 8, n. 5, p. 319, doi. 10.3109/10611860008997909

By:

Khan, Alim;
Sommer, Wolfgang;
Fuxe, Kjell;
Akhtar, Saghir

Publication type:

Article

Studies on Uptake, Sub-Cellular Trafficking and Efflux of Antisense Oligodeoxynucleotides in Glioma Cells using Self-Assembling Cationic Lipoplexes as Delivery Systems.

Published in:

Journal of Drug Targeting, 1999, v. 7, n. 5, p. 373, doi. 10.3109/10611869909085520

By:

Islam, Aminul;
Handley, Sheila L.;
Thompson, Kevin S.J.;
Akhtar, Saghir

Publication type:

Article

Antisense Technology: Selection and Delivery of Optimally Acting Antisense Oligonucleotides.

Published in:

Journal of Drug Targeting, 1998, v. 5, n. 4, p. 225, doi. 10.3109/10611869808995877

By:

Akhtar, Saghir

Publication type:

Article

Development of a Sustained-Release Biodegradable Polymer Delivery System for Site-Specific Delivery of Oligonucleotides: Characterization of P(LA-GA) Copolymer Microspheres In Vitro.

Published in:

Journal of Drug Targeting, 1998, v. 5, n. 4, p. 291, doi. 10.3109/10611869808995882

By:

Lewis, Karen J.;
Irwin, William J.;
Akhtar, Saghir

Publication type:

Article

Angiotensin-(1-7) Downregulates Diabetes-Induced cGMP Phosphodiesterase Activation in Rat Corpus Cavernosum.

Published in:

BioMed Research International, 2017, v. 2017, p. 1, doi. 10.1155/2017/5084961

By:

Dhaunsi, Gursev S.;
Yousif, Mariam;
Makki, Batoul;
Akhtar, Saghir;
Benter, Ibrahim F.

Publication type:

Article

The Role of Epidermal Growth Factor Receptor in Diabetes-Induced Cardiac Dysfunction.

Published in:

BioImpacts, 2013, v. 3, n. 1, p. 5, doi. 10.5681/bi.2013.008

By:

Akhtar, Saghir;
Benter, Ibrahim Fadil

Publication type:

Article

An Updated Review of the Biomarkers of Response to Immune Checkpoint Inhibitors in Merkel Cell Carcinoma: Merkel Cell Carcinoma and Immunotherapy.

Published in:

Cancers, 2023, v. 15, n. 20, p. 5084, doi. 10.3390/cancers15205084

By:

Fojnica, Adnan;
Ljuca, Kenana;
Akhtar, Saghir;
Gatalica, Zoran;
Vranic, Semir

Publication type:

Article

Angiotensin-(1-7) Via the Mas Receptor Alleviates the Diabetes-Induced Decrease in GFAP and GAP-43 Immunoreactivity with Concomitant Reduction in the COX-2 in Hippocampal Formation: An Immunohistochemical Study.

Published in:

Cellular & Molecular Neurobiology, 2012, v. 32, n. 8, p. 1323, doi. 10.1007/s10571-012-9858-7

By:

Renno, Waleed;
Al-Banaw, Anwar;
George, Preethi;
Abu-Ghefreh, Asmaa;
Akhtar, Saghir;
Benter, Ibrahim

Publication type:

Article

Is there truly an increase in risk of cardiovascular and hematological adverse events with vascular endothelial growth factor receptor tyrosine kinase inhibitors?

Published in:

Expert Opinion on Drug Safety, 2020, v. 19, n. 2, p. 223, doi. 10.1080/14740338.2020.1691167

By:

Furuya-Kanamori, Luis;
Doi, Suhail Ar;
Onitilo, Adedayo;
Akhtar, Saghir

Publication type:

Article

Translational Medicine: A Requirement for Effective Health Care in the Future.

Published in:

2016

By:

Akhtar, Saghir;
Albert, Manuel J.

Publication type:

journal article

In honour of Professor Jackie Ying, recipient of the Journal of Drug Targeting's Lifetime Achievement Award for 2020.

Published in:

2020

By:

Akhtar, Saghir

Publication type:

Editorial

Pharmacotherapy in COVID-19 patients: a review of ACE2-raising drugs and their clinical safety.

Published in:

Journal of Drug Targeting, 2020, v. 28, n. 7/8, p. 683, doi. 10.1080/1061186X.2020.1797754

By:

Akhtar, Saghir;
Benter, Ibrahim F.;
Danjuma, Mohammed I.;
Doi, Suhail A. R.;
Hasan, Syed S.;
Habib, Abdella M.

Publication type:

Article

In honour of Professor Patrick Couvreur, recipient of the Journal Of Drug Targeting's Lifetime Achievement Award For 2019.

Published in:

2019

By:

Akhtar, Saghir

Publication type:

Editorial

In honour of Professor Leaf Huang, recipient of the Journal of Drug Targeting’s life-time achievement award for 2018.

Published in:

Journal of Drug Targeting, 2018, v. 26, n. 5/6, p. 383, doi. 10.1080/1061186X.2018.1440923

By:

Akhtar, Saghir

Publication type:

Article

In honour of Professor Ruth Duncan, recipient of the Journal of Drug Targeting’s Lifetime Achievement Award for 2017.

Published in:

Journal of Drug Targeting, 2017, v. 25, n. 9/10, p. 755, doi. 10.1080/1061186X.2017.1379225

By:

Akhtar, Saghir

Publication type:

Article

In honour of Professor Pieter R Cullis, recipient of the Journal of Drug Targeting’s Lifetime Achievement Award for 2016.

Published in:

Journal of Drug Targeting, 2016, v. 24, n. 9, p. 759, doi. 10.1080/1061186X.2016.1241511

By:

Akhtar, Saghir

Publication type:

Article

Editorial: In honour of Professor Robert S. Langer, Recipient of the Journal of Drug Targeting’s Life-time Achievement Award for 2015.

Published in:

2015

By:

Akhtar, Saghir

Publication type:

Editorial

The dual targeting of EGFR and ErbB2 with the inhibitor Lapatinib corrects high glucose-induced apoptosis and vascular dysfunction by opposing multiple diabetes-induced signaling changes.

Published in:

Journal of Drug Targeting, 2015, v. 23, n. 6, p. 506, doi. 10.3109/1061186X.2015.1057150

By:

Benter, Ibrahim F.;
Sarkhou, Fatima;
Al-Khaldi, Abeer T.;
Chandrasekhar, Bindu;
Attur, Sreeja;
Dhaunsi, Gursev S.;
Yousif, Mariam H. M.;
Akhtar, Saghir

Publication type:

Article

In honour of Professor Kazunori Kataoka, recipient of the Journal of Drug Targeting's Life-time Achievement Award for 2014.

Published in:

Journal of Drug Targeting, 2014, v. 22, n. 7, p. 553, doi. 10.3109/1061186X.2014.932362

By:

Akhtar, Saghir

Publication type:

Article

In honour of Professor Vladimir Torchilin, Recipient of the Journal of Drug Targeting's Life-Time Achievement Award for 2013.

Published in:

Journal of Drug Targeting, 2013, v. 21, n. 10, p. 885, doi. 10.3109/1061186X.2013.837621

By:

Akhtar, Saghir

Publication type:

Article

In honour of Professor Mitsuru Hashida, Recipient of the Journal of Drug Targeting's Life-time Achievement Award for 2012.

Published in:

Journal of Drug Targeting, 2012, v. 20, n. 9, p. 721, doi. 10.3109/1061186X.2012.728897

By:

Akhtar, Saghir

Publication type:

Article

In honour of Professor Jindřřich (Henry) Kopečček, Recipient of the Journal of Drug Targeting's Life-Time Achievement Award for 2011.

Published in:

Journal of Drug Targeting, 2011, v. 19, n. 10, p. 857, doi. 10.3109/1061186X.2011.633340

By:

Akhtar, Saghir

Publication type:

Article

In honor of Professor S. S. (Bob) Davis, Recipient of the Journal of Drug Targeting's Life-time Achievement Award for 2010.

Published in:

Journal of Drug Targeting, 2010, v. 18, n. 10, p. 701, doi. 10.3109/1061186X.2010.529268

By:

Akhtar, Saghir

Publication type:

Article

Editorial: In honor of Professor Peter Paul Speiser, Recipient of the Journal of Drug Targeting’s Life-time Achievement Award for 2009.

Published in:

Journal of Drug Targeting, 2009, v. 17, n. 8, p. 561, doi. 10.1080/10611860903090436

By:

Akhtar, Saghir

Publication type:

Article

Oral delivery of siRNA and antisense oligonucleotides.

Published in:

Journal of Drug Targeting, 2009, v. 17, n. 7, p. 491, doi. 10.1080/10611860903057674

By:

Akhtar, Saghir

Publication type:

Article

In honour of Professor Gregory Gregoriadis, recipient of the Journal of Drug Targeting's Lifetime Achievement Award for 2008.

Published in:

Journal of Drug Targeting, 2008, v. 16, n. 7/8, p. 517, doi. 10.1080/10611860802230273

By:

Akhtar, Saghir

Publication type:

Article

Editorial: In honour of Professor Hiroshi Maeda, Recipient of the Journal of Drug Targeting's Life-time Achievement Award for 2007.

Published in:

Journal of Drug Targeting, 2007, v. 15, n. 7/8, p. 455, doi. 10.1080/10611860701507482

By:

Akhtar, Saghir

Publication type:

Article

Toxicogenomics of drug delivery systems: Exploiting delivery system-induced changes in target gene expression to enhance siRNA activity.

Published in:

Journal of Drug Targeting, 2007, v. 15, n. 1, p. 83, doi. 10.1080/10611860601151860

By:

Hollins, Andrew J.;
Omidi, Yadollah;
Benter, Ibrahim F.;
Akhtar, Saghir

Publication type:

Article