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Are senescence and exhaustion intertwined or unrelated processes that compromise immunity?
- Published in:
- 2011
- By:
- Publication type:
- journal article
The dynamic co-evolution of memory and regulatory CD4<sup>+</sup> T cells in the periphery.
- Published in:
- Nature Reviews Immunology, 2007, v. 7, n. 3, p. 231, doi. 10.1038/nri2037
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- Publication type:
- Article
Will telomere erosion lead to a loss of T-cell memory?
- Published in:
- 2004
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- Publication type:
- journal article
The effects of dietary supplementation with inulin and inulin‐propionate ester on hepatic steatosis in adults with non‐alcoholic fatty liver disease.
- Published in:
- Diabetes, Obesity & Metabolism, 2019, v. 21, n. 2, p. 372, doi. 10.1111/dom.13500
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- Publication type:
- Article
Herbimycin A accelerates the induction of apoptosis following etoposide treatment or γ-irradiation of bcr/abl-positive leukaemia cells.
- Published in:
- Oncogene, 1998, v. 16, n. 12, p. 1533, doi. 10.1038/sj.onc.1201680
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- Publication type:
- Article
CD4+CD45RA+T cells from adults respond to recall antigens after CD28 ligation.
- Published in:
- International Immunology, 1996, v. 8, n. 11, p. 1737, doi. 10.1093/intimm/8.11.1737
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- Publication type:
- Article
KLRG1—more than a marker for T cell senescence.
- Published in:
- Age, 2009, v. 31, n. 4, p. 285, doi. 10.1007/s11357-009-9100-9
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- Publication type:
- Article
Transcriptomic landscape of skin lesions in cutaneous leishmaniasis reveals a strong CD8<sup>+</sup> T cell immunosenescence signature linked to immunopathology.
- Published in:
- Immunology, 2021, v. 164, n. 4, p. 754, doi. 10.1111/imm.13410
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- Publication type:
- Article
Compartmentalized cytotoxic immune response leads to distinct pathogenic roles of natural killer and senescent CD8<sup>+</sup> T cells in human cutaneous leishmaniasis.
- Published in:
- Immunology, 2020, v. 159, n. 4, p. 429, doi. 10.1111/imm.13173
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- Publication type:
- Article
Senescent cells evade immune clearance via HLA-E-mediated NK and CD8<sup>+</sup> T cell inhibition.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10335-5
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- Publication type:
- Article
Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer.
- Published in:
- Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1156743
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- Publication type:
- Article
CD4<sup>+</sup>CD57<sup>+</sup> senescent T cells as promoters of systemic lupus erythematosus pathogenesis and the therapeutic potential of senolytic BCL‐2 inhibitor.
- Published in:
- European Journal of Immunology, 2024, v. 54, n. 7, p. 1, doi. 10.1002/eji.202350603
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- Publication type:
- Article
Blockade of PD-1 or p38 MAP kinase signaling enhances senescent human CD8<sup>+</sup> T-cell proliferation by distinct pathways.
- Published in:
- European Journal of Immunology, 2015, v. 45, n. 5, p. 1441, doi. 10.1002/eji.201445312
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- Publication type:
- Article
GATA3 induces mitochondrial biogenesis in primary human CD4+ T cells during DNA damage.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23715-7
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- Publication type:
- Article
Derivation of marker gene signatures from human skin and their use in the interpretation of the transcriptional changes associated with dermatological disorders.
- Published in:
- Journal of Pathology, 2017, v. 241, n. 5, p. 600, doi. 10.1002/path.4864
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- Publication type:
- Article
Role of bcl-2 and Apoptosis in Viral Infections.
- Published in:
- International Archives of Allergy & Immunology, 1994, v. 105, n. 4, p. 359, doi. 10.1159/000236783
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- Publication type:
- Article
The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells.
- Published in:
- Nature Immunology, 2014, v. 15, n. 10, p. 965, doi. 10.1038/ni.2981
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- Publication type:
- Article
Analysis of stem-cell-like properties of human CD161++IL-18Rα+ memory CD8+ T cells.
- Published in:
- International Immunology, 2012, v. 24, n. 10, p. 625, doi. 10.1093/intimm/dxs069
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- Publication type:
- Article
Loss of CD28 expression on CD8+ T cells is induced by IL-2 receptor γ chain signalling cytokines and type I IFN, and increases susceptibility to activation-induced apoptosis.
- Published in:
- International Immunology, 2000, v. 12, n. 7, p. 1005, doi. 10.1093/intimm/12.7.1005
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- Publication type:
- Article
Virus-specific T lymphocytes home to the skin during natural dengue infection.
- Published in:
- Science Translational Medicine, 2015, v. 7, n. 278, p. 1, doi. 10.1126/scitranslmed.aaa0526
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- Publication type:
- Article
p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells.
- Published in:
- 2014
- By:
- Publication type:
- journal article
p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8<sup>+</sup> T cells.
- Published in:
- Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4004, doi. 10.1172/JCI75051
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- Publication type:
- Article
The kinetics of CD4+Foxp3+ T cell accumulation during a human cutaneous antigen-specific memory response in vivo.
- Published in:
- 2008
- By:
- Publication type:
- journal article
Human CD4<sup>+</sup>CD25<sup>hi</sup>Foxp3<sup>+</sup> regulatory T cells are derived by rapid turnover of memory populations in vivo.
- Published in:
- Journal of Clinical Investigation, 2006, v. 116, n. 9, p. 2423, doi. 10.1172/JCI28941
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- Publication type:
- Article
Tonsillar homing of Epstein-Barr virus-specific CD8+ T cells and the virus-host balance.
- Published in:
- 2005
- By:
- Publication type:
- journal article
RGD peptides induce apoptosis by direct caspase-3 activation.
- Published in:
- Nature, 1999, v. 397, n. 6719, p. 534, doi. 10.1038/17409
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- Publication type:
- Article
Convergence of Innate and Adaptive Immunity During Human Aging.
- Published in:
- Frontiers in Immunology, 2016, v. 7, p. 1, doi. 10.3389/fimmu.2016.00445
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- Publication type:
- Article
Sicilian semi- and supercentenarians: identification of age-related T-cell immunophenotype to define longevity trait.
- Published in:
- Clinical & Experimental Immunology, 2023, v. 214, n. 1, p. 61, doi. 10.1093/cei/uxad074
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- Publication type:
- Article
Phenotypic Analysis of IL-10-Treated Macrophages Using the Monoclonal Antibodies RFD1 and RFD7.
- Published in:
- Pathobiology, 1999, v. 67, n. 5/6, p. 249, doi. 10.1159/000028103
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- Publication type:
- Article
Post-resolution macrophages shape long-term tissue immunity and integrity in a mouse model of pneumococcal pneumonia.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48138-y
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- Publication type:
- Article
The p38 mitogen-activated protein kinase cascade modulates T helper type 17 differentiation and functionality in multiple sclerosis.
- Published in:
- Immunology, 2015, v. 146, n. 2, p. 251, doi. 10.1111/imm.12497
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- Publication type:
- Article
Multifunctional cytomegalovirus (CMV)-specific CD8<sup>+</sup> T cells are not restricted by telomere-related senescence in young or old adults.
- Published in:
- Immunology, 2015, v. 144, n. 4, p. 549, doi. 10.1111/imm.12409
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- Publication type:
- Article
Reversal of functional defects in highly differentiated young and old CD8 T cells by PDL blockade.
- Published in:
- Immunology, 2012, v. 135, n. 4, p. 355, doi. 10.1111/j.1365-2567.2011.03550.x
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- Publication type:
- Article
Cytomegalovirus infection induces the accumulation of short-lived, multifunctional CD4.
- Published in:
- Immunology, 2011, v. 132, n. 3, p. 326, doi. 10.1111/j.1365-2567.2010.03386.x
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- Publication type:
- Article
Human cytomegalovirus-specific CD8.
- Published in:
- Immunology, 2011, v. 132, n. 1, p. 27, doi. 10.1111/j.1365-2567.2010.03334.x
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- Publication type:
- Article
Prolonged exposure of naïve CD8<sup>+</sup> T cells to interleukin-7 or interleukin-15 stimulates proliferation without differentiation or loss of telomere length.
- Published in:
- Immunology, 2006, v. 119, n. 2, p. 243, doi. 10.1111/j.1365-2567.2006.02429.x
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- Publication type:
- Article
Regulatory T cells in human disease and their potential for therapeutic manipulation.
- Published in:
- Immunology, 2006, v. 118, n. 1, p. 1, doi. 10.1111/j.1365-2567.2006.02348.x
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- Publication type:
- Article
The peripheral generation of CD4[sup+] CD25[sup+] regulatory T cells.
- Published in:
- Immunology, 2003, v. 109, n. 3, p. 319, doi. 10.1046/j.1365-2567.2003.01678.x
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- Publication type:
- Article
Human natural killer cells mediate adaptive immunity to viral antigens.
- Published in:
- Science Immunology, 2019, v. 4, n. 35, p. 1, doi. 10.1126/sciimmunol.aat8116
- By:
- Publication type:
- Article
Antigen-specific T cell suppression by human CD4.
- Published in:
- European Journal of Immunology, 2002, v. 32, n. 6, p. 1621, doi. 10.1002/1521-4141(200206)32:6<1621::AID-IMMU1621>3.0.CO;2-Q
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- Publication type:
- Article
Cytokine-mediated inhibition of apoptosis in non-transformed T cells and neutrophils can be dissociated from protein kinase B activation.
- Published in:
- European Journal of Immunology, 2002, v. 32, n. 2, p. 486, doi. 10.1002/1521-4141(200202)32:2<486::AID-IMMU486>3.0.CO;2-U
- By:
- Publication type:
- Article
Human anergic/suppressive CD4.
- Published in:
- European Journal of Immunology, 2001, v. 31, n. 4, p. 1122, doi. 10.1002/1521-4141(200104)31:4<1122::AID-IMMU1122>3.0.CO;2-P
- By:
- Publication type:
- Article
Inhibition of T cell apoptosis by IFN-β rapidly reverses nuclear translocation of protein kinase C-δ.
- Published in:
- European Journal of Immunology, 1999, v. 29, n. 8, p. 2603, doi. 10.1002/(SICI)1521-4141(199908)29:08<2603::AID-IMMU2603>3.0.CO;2-L
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- Publication type:
- Article
Interferon-β mediates stromal cell rescue of T cells from apoptosis.
- Published in:
- European Journal of Immunology, 1999, v. 29, n. 3, p. 1041, doi. 10.1002/(SICI)1521-4141(199903)29:03<1041::AID-IMMU1041>3.0.CO;2-#
- By:
- Publication type:
- Article
Interleukin-2 receptor common γ-chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: Selective induction of anti-apoptotic ( bcl-2, bcl-x.
- Published in:
- European Journal of Immunology, 1996, v. 26, n. 2, p. 294, doi. 10.1002/eji.1830260204
- By:
- Publication type:
- Article
The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis.
- Published in:
- European Journal of Immunology, 1994, v. 24, n. 4, p. 892, doi. 10.1002/eji.1830240417
- By:
- Publication type:
- Article
Human CD4.
- Published in:
- European Journal of Immunology, 1991, v. 21, n. 10, p. 2517, doi. 10.1002/eji.1830211031
- By:
- Publication type:
- Article
The Characterization of Varicella Zoster Virus-Specific T Cells in Skin and Blood during Aging.
- Published in:
- Journal of Investigative Dermatology, 2015, v. 135, n. 7, p. 1752, doi. 10.1038/jid.2015.63
- By:
- Publication type:
- Article
CMV and Immunosenescence: from basics to clinics.
- Published in:
- Immunity & Ageing, 2012, v. 9, p. 1, doi. 10.1186/1742-4933-9-23
- By:
- Publication type:
- Article
Senescent T cells: Beneficial and detrimental roles.
- Published in:
- Immunological Reviews, 2023, v. 316, n. 1, p. 160, doi. 10.1111/imr.13206
- By:
- Publication type:
- Article