Works matching AU Akasaka, Hiroaki

Results: 27

Radiation suppresses liver metastases via exosome secretion in pancreatic cancer cells.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-08826-1

By:

Nakaoka, Ai;
Salah, Mohammed;
Ruixian, Zhangzhu;
Nakahana, Makiko;
Shimizu, Yasuyuki;
Qin, Qin;
Zhang, Qu;
Mukumoto, Naritoshi;
Kobayashi, Kana;
Ikegaki, Yukihiro;
Akasaka, Hiroaki;
Inubushi, Sachiko;
Koma, Yu-ichiro;
Ishihara, Takeaki;
Miyawaki, Daisuke;
Sasayama, Takashi;
Sasaki, Ryohei

Publication type:

Article

Structural insights into ligand recognition and G protein preferences across histamine receptors.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08363-7

By:

Matsuzaki, Yuma;
Sano, Fumiya K.;
Oshima, Hidetaka S.;
Akasaka, Hiroaki;
Kobayashi, Kazuhiro;
Tanaka, Tatsuki;
Itoh, Yuzuru;
Shihoya, Wataru;
Kise, Yoshiaki;
Kusakizako, Tsukasa;
Inoue, Asuka;
Nureki, Osamu

Publication type:

Article

Structural mechanisms of potent lysophosphatidic acid receptor 1 activation by nonlipid basic agonists.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07152-y

By:

Akasaka, Hiroaki;
Sano, Fumiya K.;
Shihoya, Wataru;
Nureki, Osamu

Publication type:

Article

Structural visualization of small molecule recognition by CXCR3 uncovers dual-agonism in the CXCR3-CXCR7 system.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58264-w

By:

Saha, Shirsha;
Sano, Fumiya K.;
Sharma, Saloni;
Ganguly, Manisankar;
Dalal, Annu;
Mishra, Sudha;
Tiwari, Divyanshu;
Akasaka, Hiroaki;
Kobayashi, Takaaki A.;
Roy, Nabarun;
Zaidi, Nashrah;
Itoh, Yuzuru;
Leurs, Rob;
Banerjee, Ramanuj;
Shihoya, Wataru;
Nureki, Osamu;
Shukla, Arun K.

Publication type:

Article

Structural insights into the agonist selectivity of the adenosine A3 receptor.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53473-1

By:

Oshima, Hidetaka S.;
Ogawa, Akiko;
Sano, Fumiya K.;
Akasaka, Hiroaki;
Kawakami, Tomoyoshi;
Iwama, Aika;
Okamoto, Hiroyuki H.;
Nagiri, Chisae;
Wei, Fan-Yan;
Shihoya, Wataru;
Nureki, Osamu

Publication type:

Article

Structure and dynamics of the pyroglutamylated RF-amide peptide QRFP receptor GPR103.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49030-5

By:

Iwama, Aika;
Kise, Ryoji;
Akasaka, Hiroaki;
Sano, Fumiya K.;
Oshima, Hidetaka S.;
Inoue, Asuka;
Shihoya, Wataru;
Nureki, Osamu

Publication type:

Article

Exosome-mediated radiosensitizing effect on neighboring cancer cells via increase in intracellular levels of reactive oxygen species.

Published in:

Oncology Reports, 2021, v. 45, n. 4, p. N.PAG, doi. 10.3892/or.2021.7964

By:

Nakaoka, Ai;
Nakahana, Makiko;
Inubushi, Sachiko;
Akasaka, Hiroaki;
Salah, Mohammed;
Fujita, Yoshiko;
Kubota, Hikaru;
Hassan, Mennaallah;
Nishikawa, Ryo;
Mukumoto, Naritoshi;
Ishihara, Takeaki;
Miyawaki, Daisuke;
Sasayama, Takashi;
Sasaki, Ryohei

Publication type:

Article

Respiratory motion tracking of spine stereotactic radiotherapy in prone position.

Published in:

Journal of Applied Clinical Medical Physics, 2023, v. 24, n. 5, p. 1, doi. 10.1002/acm2.13910

By:

Mizonobe, Kazufusa;
Akasaka, Hiroaki;
Uehara, Kazuyuki;
Oki, Yuya;
Nakayama, Masao;
Tamura, Shuhei;
Munetomo, Yoshiki;
Kubo, Katsumaro;
Kawaguchi, Hiroki;
Harada, Aya;
Mayahara, Hiroshi

Publication type:

Article

Fiducial marker position affects target volume in stereotactic lung irradiation.

Published in:

Journal of Applied Clinical Medical Physics, 2022, v. 23, n. 6, p. 1, doi. 10.1002/acm2.13596

By:

Akasaka, Hiroaki;
Mizonobe, Kazufusa;
Oki, Yuya;
Uehara, Kazuyuki;
Nakayama, Masao;
Tamura, Shuhei;
Munetomo, Yoshiki;
Kawaguchi, Haruna;
Ishida, Jun;
Harada, Aya;
Ishihara, Takeaki;
Kubota, Hikaru;
Kawaguchi, Hiroki;
Sasaki, Ryohei;
Mayahara, Hiroshi

Publication type:

Article

Plan comparison of prostate stereotactic radiotherapy in spacer implant patients.

Published in:

Journal of Applied Clinical Medical Physics, 2021, v. 22, n. 9, p. 280, doi. 10.1002/acm2.13387

By:

Oki, Yuya;
Uehara, Kazuyuki;
Mizonobe, Kazufusa;
Akasaka, Hiroaki;
Shiota, Yuichirou;
Sakamoto, Risako;
Harada, Aya;
Kitatani, Keiji;
Yabuuchi, Tomonori;
Miyazaki, Shuichirou;
Hattori, Takayuki;
Mayahara, Hiroshi

Publication type:

Article

Novel artifact‐robust and highly visible zinc solid fiducial marker for kilovoltage x‐ray image‐guided radiation therapy.

Published in:

Medical Physics, 2020, v. 47, n. 10, p. 4703, doi. 10.1002/mp.14412

By:

Wang, Tianyuan;
Inubushi, Sachiko;
Ikeo, Naoko;
Mukai, Toshiji;
Okumura, Keisuke;
Akasaka, Hiroaki;
Yada, Ryuichi;
Yoshida, Kenji;
Miyawaki, Daisuke;
Ishihara, Takeaki;
Nakaoka, Ai;
Sasaki, Ryohei

Publication type:

Article

Real‐time in vivo dosimetry system based on an optical fiber‐coupled microsized photostimulable phosphor for stereotactic body radiation therapy.

Published in:

Medical Physics, 2020, v. 47, n. 10, p. 5235, doi. 10.1002/mp.14383

By:

Yada, Ryuichi;
Maenaka, Kazusuke;
Miyamoto, Shuji;
Okada, Go;
Sasakura, Aki;
Ashida, Motoi;
Adachi, Masashi;
Sato, Tatsuhiko;
Wang, Tianyuan;
Akasaka, Hiroaki;
Mukumoto, Naritoshi;
Shimizu, Yasuyuki;
Sasaki, Ryohei

Publication type:

Article

Reactive oxygen species-inducing titanium peroxide nanoparticles as promising radiosensitizers for eliminating pancreatic cancer stem cells.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2022, v. 41, n. 1, p. 1, doi. 10.1186/s13046-022-02358-6

By:

Salah, Mohammed;
Akasaka, Hiroaki;
Shimizu, Yasuyuki;
Morita, Kenta;
Nishimura, Yuya;
Kubota, Hikaru;
Kawaguchi, Hiroki;
Sogawa, Tomomi;
Mukumoto, Naritoshi;
Ogino, Chiaki;
Sasaki, Ryohei

Publication type:

Article

Ultrasound-stimulated Microbubbles for Treatment of Pancreatic Cancer Cells with Radiation and Nanoparticles: In vitro Study.

Published in:

Journal of Medical Physics, 2024, v. 49, n. 3, p. 326, doi. 10.4103/jmp.jmp_30_24

By:

Masao Nakayama;
Ayaha Noda;
Hiroaki Akasaka;
Takahiro Tominaga;
McCorkell, Giulia;
Moshi Geso;
Ryohei Sasaki

Publication type:

Article

Titanium Dioxide-Based Nanoparticles to Enhance Radiation Therapy for Cancer: A Literature Review.

Published in:

Journal of Nanotheranostics, 2024, v. 5, n. 2, p. 60, doi. 10.3390/jnt5020004

By:

Nakayama, Masao;
Akasaka, Hiroaki;
Sasaki, Ryohei;
Geso, Moshi

Publication type:

Article

Structure of the active Gi-coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33121-2

By:

Akasaka, Hiroaki;
Tanaka, Tatsuki;
Sano, Fumiya K.;
Matsuzaki, Yuma;
Shihoya, Wataru;
Nureki, Osamu

Publication type:

Article

Evaluation of robustness of optimization methods in breast intensity-modulated radiation therapy using TomoTherapy.

Published in:

Physical & Engineering Sciences in Medicine, 2024, v. 47, n. 2, p. 465, doi. 10.1007/s13246-023-01377-7

By:

Oki, Yuya;
Akasaka, Hiroaki;
Uehara, Kazuyuki;
Mizonobe, Kazufusa;
Sawada, Masanobu;
Nagata, Junya;
Harada, Aya;
Mayahara, Hiroshi

Publication type:

Article

Investigation of the potential of using TiO2 nanoparticles as a contrast agent in computed tomography and magnetic resonance imaging.

Published in:

Applied Nanoscience, 2020, v. 10, n. 8, p. 3143, doi. 10.1007/s13204-019-01098-y

By:

Akasaka, Hiroaki;
Mukumoto, Naritoshi;
Nakayama, Masao;
Wang, Tianyuan;
Yada, Ryuichi;
Shimizu, Yasuyuki;
Inubushi, Sachiko;
Kyotani, Katsusuke;
Okumura, Keisuke;
Miyamoto, Masanori;
Nakaoka, Ai;
Morita, Kenta;
Nishimura, Yuya;
Ogino, Chiaki;
Sasaki, Ryohei

Publication type:

Article

A treatment planning study comparison between supine and prone position for different lung tumour locations using CyberKnife TPS.

Published in:

Journal of Radiotherapy in Practice, 2022, v. 21, n. 3, p. 309, doi. 10.1017/S1460396920001193

By:

Akasaka, Hiroaki;
Mizonobe, Kazufusa;
Oki, Yuya;
Uehara, Kazuyuki;
Harada, Aya;
Miyazaki, Shuichiro;
Kitatani, Keiji;
Yabuuchi, Tomonori;
Ishihara, Takeaki;
Miyawaki, Daisuke;
Nakayama, Masao;
Mukumoto, Naritoshi;
Yada, Ryuichi;
Nakaoka, Ai;
Kubota, Hikaru;
Kawaguchi, Hiroki;
Seno, Satoshi;
Sasaki, Ryohei;
Mayahara, Hiroshi

Publication type:

Article

The air gap between bolus and skin affects dose distribution in helical and direct tomotherapy.

Published in:

Journal of Radiotherapy in Practice, 2021, v. 20, n. 3, p. 294, doi. 10.1017/S1460396920000333

By:

Akasaka, Hiroaki;
Oki, Yuya;
Mizonobe, Kazufusa;
Uehara, Kazuyuki;
Mayahara, Hiroshi;
Harada, Aya;
Hashimoto, Naoki;
Kitatani, Keiji;
Yabuuchi, Tomonori;
Ishihara, Takeaki;
Iwashita, Kazuma;
Miyawaki, Daisuke;
Mukumoto, Naritoshi;
Nakaoka, Ai;
Sasaki, Ryohei

Publication type:

Article

Cryo-EM structure of the endothelin-1- ETB- Gi complex.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85821

By:

Sano, Fumiya K.;
Hiroaki Akasaka;
Wataru Shihoya;
Osamu Nureki

Publication type:

Article

A Comparative Assessment of Mechanisms and Effectiveness of Radiosensitization by Titanium Peroxide and Gold Nanoparticles.

Published in:

Nanomaterials (2079-4991), 2020, v. 10, n. 6, p. 1125, doi. 10.3390/nano10061125

By:

Hassan, Mennaallah;
Nakayama, Masao;
Salah, Mohammed;
Akasaka, Hiroaki;
Kubota, Hikaru;
Nakahana, Makiko;
Tagawa, Tatsuichiro;
Morita, Kenta;
Nakaoka, Ai;
Ishihara, Takeaki;
Miyawaki, Daisuke;
Yoshida, Kenji;
Nishimura, Yuya;
Ogino, Chiaki;
Sasaki, Ryohei

Publication type:

Article

Cryo-EM structure of a blue-shifted channelrhodopsin from Klebsormidium nitens.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59299-9

By:

Wang, Yuzhu Z.;
Natsume, Koki;
Tanaka, Tatsuki;
Hososhima, Shoko;
Tashiro, Rintaro;
Sano, Fumiya K.;
Akasaka, Hiroaki;
Tsunoda, Satoshi P.;
Shihoya, Wataru;
Kandori, Hideki;
Nureki, Osamu

Publication type:

Article

Structure of a lasso peptide bound ETB receptor provides insights into the mechanism of GPCR inverse agonism.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57960-x

By:

Shihoya, Wataru;
Akasaka, Hiroaki;
Jordan, Peter A.;
Lechner, Anna;
Okada, Bethany K.;
Costa Machado da Cruz, Gabriella;
Sano, Fumiya K.;
Tanaka, Tatsuki;
Kawahara, Ryo;
Chaudhari, Rajan;
Masamune, Hiroko;
Burk, Mark J.;
Nureki, Osamu

Publication type:

Article

MGDG extracted from spinach enhances the cytotoxicity of radiation in pancreatic cancer cells.

Published in:

Radiation Oncology, 2016, v. 11, p. 1, doi. 10.1186/s13014-016-0729-0

By:

Hiroaki Akasaka;
Yoshiyuki Mizushina;
Kenji Yoshida;
Yasuo Ejima;
Naritoshi Mukumoto;
Tianyuan Wang;
Sachiko Inubushi;
Masao Nakayama;
Yuki Wakahara;
Ryohei Sasaki

Publication type:

Article

Titanium peroxide nanoparticles enhanced cytotoxic effects of X-ray irradiation against pancreatic cancer model through reactive oxygen species generation in vitro and in vivo.

Published in:

2016

By:

Masao Nakayama;
Ryohei Sasaki;
Chiaki Ogino;
Tsutomu Tanaka;
Kenta Morita;
Mitsuo Umetsu;
Satoshi Ohara;
Zhenquan Tan;
Yuya Nishimura;
Hiroaki Akasaka;
Kazuyoshi Sato;
Chiya Numako;
Seiichi Takami;
Akihiko Kondo;
Nakayama, Masao;
Sasaki, Ryohei;
Ogino, Chiaki;
Tanaka, Tsutomu;
Morita, Kenta;
Umetsu, Mitsuo

Publication type:

journal article

Patterns of failure after multimodal treatments for high-grade glioma: effectiveness of MIB-1 labeling index.

Published in:

Radiation Oncology, 2012, v. 7, n. 1, p. 104, doi. 10.1186/1748-717X-7-104

By:

Kazuyuki Uehara;
Takashi Sasayama;
Daisuke Miyawaki;
Hideki Nishimura;
Kenji Yoshida;
Yoshiaki Okamoto;
Naritoshi Mukumoto;
Hiroaki Akasaka;
Masamitsu Nishihara;
Osamu Fujii;
Toshinori Soejima;
Kazuro Sugimura;
Eiji Kohmura;
Ryohei Sasaki

Publication type:

Article

Works matching AU Akasaka, Hiroaki

Radiation suppresses liver metastases via exosome secretion in pancreatic cancer cells.

Structural insights into ligand recognition and G protein preferences across histamine receptors.

Structural mechanisms of potent lysophosphatidic acid receptor 1 activation by nonlipid basic agonists.

Structural visualization of small molecule recognition by CXCR3 uncovers dual-agonism in the CXCR3-CXCR7 system.

Structural insights into the agonist selectivity of the adenosine A<sub>3</sub> receptor.

Structure and dynamics of the pyroglutamylated RF-amide peptide QRFP receptor GPR103.

Exosome-mediated radiosensitizing effect on neighboring cancer cells via increase in intracellular levels of reactive oxygen species.

Respiratory motion tracking of spine stereotactic radiotherapy in prone position.

Fiducial marker position affects target volume in stereotactic lung irradiation.

Plan comparison of prostate stereotactic radiotherapy in spacer implant patients.

Novel artifact‐robust and highly visible zinc solid fiducial marker for kilovoltage x‐ray image‐guided radiation therapy.

Real‐time in vivo dosimetry system based on an optical fiber‐coupled microsized photostimulable phosphor for stereotactic body radiation therapy.

Reactive oxygen species-inducing titanium peroxide nanoparticles as promising radiosensitizers for eliminating pancreatic cancer stem cells.

Ultrasound-stimulated Microbubbles for Treatment of Pancreatic Cancer Cells with Radiation and Nanoparticles: In vitro Study.

Titanium Dioxide-Based Nanoparticles to Enhance Radiation Therapy for Cancer: A Literature Review.

Structure of the active G<sub>i</sub>-coupled human lysophosphatidic acid receptor 1 complexed with a potent agonist.

Evaluation of robustness of optimization methods in breast intensity-modulated radiation therapy using TomoTherapy.

Investigation of the potential of using TiO<sub>2</sub> nanoparticles as a contrast agent in computed tomography and magnetic resonance imaging.

A treatment planning study comparison between supine and prone position for different lung tumour locations using CyberKnife TPS.

The air gap between bolus and skin affects dose distribution in helical and direct tomotherapy.

Cryo-EM structure of the endothelin-1- ET<sub>B</sub>- G<sub>i</sub> complex.

A Comparative Assessment of Mechanisms and Effectiveness of Radiosensitization by Titanium Peroxide and Gold Nanoparticles.

Cryo-EM structure of a blue-shifted channelrhodopsin from Klebsormidium nitens.

Structure of a lasso peptide bound ET<sub>B</sub> receptor provides insights into the mechanism of GPCR inverse agonism.

MGDG extracted from spinach enhances the cytotoxicity of radiation in pancreatic cancer cells.

Titanium peroxide nanoparticles enhanced cytotoxic effects of X-ray irradiation against pancreatic cancer model through reactive oxygen species generation in vitro and in vivo.

Patterns of failure after multimodal treatments for high-grade glioma: effectiveness of MIB-1 labeling index.