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Effects of troglitazone: a new hypoglycemic agent in patients with NIDDM poorly controlled by diet therapy.
Published in:
1996
By:
- Iwamoto Y;
- Kosaka K;
- Kuzuya T;
- Akanuma Y;
- Shigeta Y;
- Kaneko T;
- Iwamoto, Y;
- Kosaka, K;
- Kuzuya, T;
- Akanuma, Y;
- Shigeta, Y;
- Kaneko, T
Publication type:
journal article
A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes K. Hara et al.: A genetic variation in the PGC-1 gene and insulin resistance.
Published in:
Diabetologia, 2002, v. 45, n. 5, p. 740, doi. 10.1007/s00125-002-0803-z
By:
- Hara, K.;
- Tobe, K.;
- Okada, T.;
- Kadowaki, H.;
- Akanuma, Y.;
- Ito, C.;
- Kimura, S.;
- Kadowaki, T.
Publication type:
Article
Insulin-independent and wortmannin-resistant targeting of IRS-3 to the plasma membrane via its pleckstrin homology domain mediates a different interaction with the insulin receptor from that of IRS-1.
Published in:
Diabetologia, 2001, v. 44, n. 8, p. 992, doi. 10.1007/s001250100587
By:
- Kaburagi, Y.;
- Satoh, S.;
- Yamamoto-Honda, R.;
- Ito, T.;
- Ueki, K.;
- Akanuma, Y.;
- Sekihara, H.;
- Kimura, S.;
- Kadowaki, T.
Publication type:
Article
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase.
Published in:
Nature Medicine, 2002, v. 8, n. 11, p. 1288, doi. 10.1038/nm788
By:
- Yamauchi, T.;
- Kamon, J.;
- Minokoshi, Y.;
- Ito, Y.;
- Waki, H.;
- Uchida, S.;
- Yamashita, S.;
- Noda, M.;
- Kita, S.;
- Ueki, K.;
- Eto, K.;
- Akanuma, Y.;
- Froguel, P.;
- Foufelle, F.;
- Ferre, P.;
- Carling, D.;
- Kimura, S.;
- Nagai, R.;
- Kahn, B.B.;
- Kadowaki, T.
Publication type:
Article
Amylase-producing lung cancer: case report and review of the literature.
Published in:
1981
By:
- Katayama, Shigehiro;
- Ikeuchi, Masatoshi;
- Kanazawa, Yasunori;
- Akanuma, Yasuo;
- Kosaka, Kinori;
- Takeuchi, Toshiyuki;
- Nakayama, Toshimasa;
- Katayama, S;
- Ikeuchi, M;
- Kanazawa, Y;
- Akanuma, Y;
- Kosaka, K;
- Takeuchi, T;
- Nakayama, T
Publication type:
journal article
Leisure-time physical activity is a significant predictor of stroke and total mortality in Japanese patients with type 2 diabetes: analysis from the Japan Diabetes Complications Study (JDCS).
Published in:
Diabetologia, 2013, v. 56, n. 5, p. 1021, doi. 10.1007/s00125-012-2810-z
By:
- Sone, H.;
- Tanaka, S.;
- Suzuki, S.;
- Seino, H.;
- Hanyu, O.;
- Sato, A.;
- Toyonaga, T.;
- Okita, K.;
- Ishibashi, S.;
- Kodama, S.;
- Akanuma, Y.;
- Yamada, N.
Publication type:
Article
Incidence and progression of diabetic retinopathy in Japanese adults with type 2 diabetes: 8 year follow-up study of the Japan Diabetes Complications Study (JDCS).
Published in:
Diabetologia, 2011, v. 54, n. 9, p. 2288, doi. 10.1007/s00125-011-2199-0
By:
- Kawasaki, R;
- Tanaka, S;
- Yamamoto, T;
- Sone, H;
- Ohashi, Y;
- Akanuma, Y;
- Yamada, N;
- Yamashita, H
Publication type:
Article
Low transition rate from normo- and low microalbuminuria to proteinuria in Japanese type 2 diabetic individuals: the Japan Diabetes Complications Study (JDCS).
Published in:
Diabetologia, 2011, v. 54, n. 5, p. 1025, doi. 10.1007/s00125-010-2025-0
By:
- Katayama, S.;
- Moriya, T.;
- Tanaka, S.;
- Yajima, Y.;
- Sone, H.;
- Iimuro, S.;
- Ohashi, Y.;
- Akanuma, Y.;
- Yamada, N.
Publication type:
Article
Long-term lifestyle intervention lowers the incidence of stroke in Japanese patients with type 2 diabetes: a nationwide multicentre randomised controlled trial (the Japan Diabetes Complications Study).
Published in:
Diabetologia, 2010, v. 53, n. 3, p. 419, doi. 10.1007/s00125-009-1622-2
By:
- Sone, H.;
- Tanaka, S.;
- Iimuro, S.;
- Oida, K.;
- Yamasaki, Y.;
- Oikawa, S.;
- Ishibashi, S.;
- Katayama, S.;
- Yamashita, H.;
- Ito, H.;
- Yoshimura, Y.;
- Ohashi, Y.;
- Akanuma, Y.;
- Yamada, N.
Publication type:
Article
Marked depletion of plasma 1,5-anhydroglucitol, a major polyol, in streptozocin-induced diabetes in rats and the effect of insulin treatment.
Published in:
1986
By:
- YAMANOUCHI, TOSHIKAZU;
- AKANUMA, HIROSHI;
- TAKAKU, FUMIMARO;
- AKANUMA, YASUO;
- Yamanouchi, T;
- Akanuma, H;
- Takaku, F;
- Akanuma, Y
Publication type:
journal article
Characteristics of insulin receptors and insulin action in human myelogenous leukemia cell line K-562.
Published in:
1985
By:
- Yamanouchi, Toshikazu;
- Tsushima, Toshio;
- Akanuma, Yasuo;
- Kasuga, Masato;
- Mizoguchi, Hideaki;
- Takaku, Fumimaro;
- Yamanouchi, T;
- Tsushima, T;
- Akanuma, Y;
- Kasuga, M;
- Mizoguchi, H;
- Takaku, F
Publication type:
journal article
Effects of anti-insulin receptor autoantibodies on the metabolism of human adipocytes.
Published in:
1978
By:
- Kasuga, M.;
- Akanuma, Y.;
- Tsushima, T.;
- Iwamoto, Y.;
- Kosaka, K.;
- Kibata, M.;
- Kawanishi, K.
Publication type:
journal article
Effect of combination therapy of troglitazone and sulphonylureas in patients with Type 2 diabetes who were poorly controlled by sulphonylurea therapy alone.
Published in:
1996
By:
- Iwamoto, Y;
- Kosaka, K;
- Kuzuya, T;
- Akanuma, Y;
- Shigeta, Y;
- Kaneko, T
Publication type:
Journal Article
Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative aldose reductase inhibitor-diabetes complications trial.
Published in:
2006
By:
- Hotta N;
- Akanuma Y;
- Kawamori R;
- Matsuoka K;
- Oka Y;
- Shichiri M;
- Toyota T;
- Nakashima M;
- Yoshimura I;
- Sakamoto N;
- Shigeta Y
Publication type:
Journal Article
The new worldwide definition of metabolic syndrome is not a better diagnostic predictor of cardiovascular disease in Japanese diabetic patients than the existing definitions: additional analysis from the Japan Diabetes Complications Study.
Published in:
2006
By:
- Sone H;
- Tanaka S;
- Ishibashi S;
- Yamasaki Y;
- Oikawa S;
- Ito H;
- Saito Y;
- Ohashi Y;
- Akanuma Y;
- Yamada N;
- Japan Diabetes Complications Study (JDCS) Group;
- Sone, Hirohito;
- Tanaka, Sachiko;
- Ishibashi, Shun;
- Yamasaki, Yoshimitsu;
- Oikawa, Shinichi;
- Ito, Hideki;
- Saito, Yasushi;
- Ohashi, Yasuo;
- Akanuma, Yasuo
Publication type:
journal article
Is the diagnosis of metabolic syndrome useful for predicting cardiovascular disease in asian diabetic patients? Analysis from the Japan Diabetes Complications Study.
Published in:
2005
By:
- Sone H;
- Mizuno S;
- Fujii H;
- Yoshimura Y;
- Yamasaki Y;
- Ishibashi S;
- Katayama S;
- Saito Y;
- Ito H;
- Ohashi Y;
- Akanuma Y;
- Yamada N;
- Japan Diabetes Complications Study Group;
- Sone, Hirohito;
- Mizuno, Sachiko;
- Fujii, Hitomi;
- Yoshimura, Yukio;
- Yamasaki, Yoshimitsu;
- Ishibashi, Shun;
- Katayama, Shigehiro
Publication type:
journal article
Apolipoprotein E polymorphism is associated with plasma cholesterol response in a 7-day hospitalization study for metabolic and dietary control in NIDDM.
Published in:
1993
By:
- Murakami, K;
- Shimizu, M;
- Yamada, N;
- Ishibashi, S;
- Shimano, H;
- Yazaki, Y;
- Akanuma, Y
Publication type:
journal article
Insulin effect during embryogenesis determines fetal growth: a possible molecular link between birth weight and susceptibility to type 2 diabetes.
Published in:
2000
By:
- Terauchi, Yasuo;
- Kubota, Naoto;
- Tamemoto, Hiroyuki;
- Sakura, Hiroshi;
- Nagai, Ryozo;
- Akanuma, Yasuo;
- Kimura, Satoshi;
- Kadowaki, Takashi;
- Terauchi, Y;
- Kubota, N;
- Tamemoto, H;
- Sakura, H;
- Nagai, R;
- Akanuma, Y;
- Kimura, S;
- Kadowaki, T
Publication type:
journal article
A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats.
Published in:
1998
By:
- Murakami, Koji;
- Tobe, Kazuyuki;
- Ide, Tomohiro;
- Mochizuki, Toshiro;
- Ohashi, Mitsuo;
- Akanuma, Yasuo;
- Yazaki, Yoshio;
- Kadowaki, Takashi;
- Murakami, K;
- Tobe, K;
- Ide, T;
- Mochizuki, T;
- Ohashi, M;
- Akanuma, Y;
- Yazaki, Y;
- Kadowaki, T
Publication type:
journal article
Sequence variations of the glucokinase gene in Japanese subjects with NIDDM.
Published in:
1993
By:
- Eto, Kazuhiro;
- Sakura, Hiroshi;
- Shimokawa, Kotaro;
- Kadowaki, Hiroko;
- Hagura, Ryoko;
- Akanuma, Yasuo;
- Yazaki, Yoshio;
- Kadowaki, Takashi;
- Eto, K;
- Sakura, H;
- Shimokawa, K;
- Kadowaki, H;
- Hagura, R;
- Akanuma, Y;
- Yazaki, Y;
- Kadowaki, T
Publication type:
journal article
Comparison of 1,5-anhydroglucitol, HbA1c, and fructosamine for detection of diabetes mellitus.
Published in:
1991
By:
- Yamanouchi, Toshikazu;
- Akanuma, Yasuo;
- Toyota, Takayoshi;
- Kuzuya, Takeshi;
- Kawai, Tadashi;
- Kawazu, Syouji;
- Yoshioka, Shigetake;
- Kanazawa, Yasunori;
- Ohta, Meisei;
- Baba, Shigeaki;
- Kosaka, Kinori;
- Yamanouchi, T;
- Akanuma, Y;
- Toyota, T;
- Kuzuya, T;
- Kawai, T;
- Kawazu, S;
- Yoshioka, S;
- Kanazawa, Y;
- Ohta, M
Publication type:
journal article
Immunological detection of phosphotyrosine-containing proteins in rat livers after insulin injection.
Published in:
1990
By:
- Tobe, Kazuyuki;
- Koshio, Osamu;
- Tashiro-Hashimoto, Yuko;
- Takaku, Fumimaro;
- Akanuma, Yasuo;
- Kasuga, Masato;
- Tobe, K;
- Koshio, O;
- Tashiro-Hashimoto, Y;
- Takaku, F;
- Akanuma, Y;
- Kasuga, M
Publication type:
journal article
Increased liver glucose-transporter protein and mRNA in streptozocin-induced diabetic rats.
Published in:
1990
By:
- Oka, Yoshitomo;
- Asano, Tomoichiro;
- Shibasaki, Yoshikazu;
- Lin, Jiann-Liang;
- Tsukuda, Katsunori;
- Akanuma, Yasuo;
- Takaku, Fumimaro;
- Oka, Y;
- Asano, T;
- Shibasaki, Y;
- Lin, J L;
- Tsukuda, K;
- Akanuma, Y;
- Takaku, F
Publication type:
journal article
Plasma 1,5-anhydro-D-glucitol as new clinical marker of glycemic control in NIDDM patients.
Published in:
1989
By:
- Yamanouchi, Toshikazu;
- Minoda, Susumu;
- Yabuuchi, Masahiko;
- Akanuma, Yasuo;
- Akanuma, Hiroshi;
- Miyashita, Hideo;
- Akaoka, Ieo;
- Yamanouchi, T;
- Minoda, S;
- Yabuuchi, M;
- Akanuma, Y;
- Akanuma, H;
- Miyashita, H;
- Akaoka, I
Publication type:
journal article
Reduction and recovery of plasma 1,5-anhydro-D-glucitol level in diabetes mellitus.
Published in:
1987
By:
- Yamanouchi, Toshikazu;
- Akanuma, Hiroshi;
- Asano, Tomoichiro;
- Konishi, Chieko;
- Akaoka, Leo;
- Akanuma, Yasuo;
- Yamanouchi, T;
- Akanuma, H;
- Asano, T;
- Konishi, C;
- Akaoka, I;
- Akanuma, Y
Publication type:
journal article
Initial phase II clinical studies on midaglizole (DG-5128). A new hypoglycemic agent.
Published in:
1987
By:
- Kawazu, S.;
- Suzuki, M.;
- Negishi, K.;
- Ishii, J.;
- Sando, H.;
- Katagiri, H.;
- Kanazawa, Y.;
- Yamanouchi, S.;
- Akanuma, Y.;
- Kajinuma, H.;
- Suzuki, K.;
- Watanabe, K.;
- Itoh, T.;
- Kobayashi, T.;
- Kosaka, K.
Publication type:
journal article
Effects of plasma infusion on plasma lipids, apoproteins and plasma enzyme activities in familial lecithin: cholesterol acyltransferase deficiency.
Published in:
European Journal of Clinical Investigation, 1984, v. 14, n. 2, p. 122, doi. 10.1111/j.1365-2362.1984.tb02100.x
By:
- MURAYAMA, N.;
- ASANO, Y.;
- KATO, K.;
- SAKAMOTO, Y.;
- HOSODA, S.;
- YAMADA, N.;
- KODAMA, T.;
- MURASE, T.;
- AKANUMA, Y.
Publication type:
Article
Positive Correlation of Serum Lecithin: Cholesterol Acyltransferase Activity with Relative Body Weight.
Published in:
European Journal of Clinical Investigation, 1973, v. 3, n. 2, p. 136, doi. 10.1111/j.1365-2362.1973.tb00341.x
By:
- Akanuma, Y.;
- Kuzuya, T.;
- Hayashi, M.;
- Ide, T.;
- Kuzuya, N.
Publication type:
Article
Effect of Antigastrin (SC-15396) on Amylase Release and 2-Deoxyglucose Uptake in Mouse Pancreatic Acini.
Published in:
Digestion, 1985, v. 31, n. 1, p. 31, doi. 10.1159/000199174
By:
- Iwamoto, Y.;
- Nakamura, R.;
- Akanuma, Y.;
- Kuzuya, T.
Publication type:
Article
Comparison of various lipid variables as predictors of coronary heart disease in Japanese men and women with type 2 diabetes: subanalysis of the Japan Diabetes Complications Study.
Published in:
2012
By:
- Sone H;
- Tanaka S;
- Iimuro S;
- Ishibashi S;
- Oikawa S;
- Shimano H;
- Katayama S;
- Ohashi Y;
- Akanuma Y;
- Yamada N;
- Japan Diabetes Complications Study Group;
- Sone, Hirohito;
- Tanaka, Sachiko;
- Tanaka, Shiro;
- Iimuro, Satoshi;
- Ishibashi, Shun;
- Oikawa, Shinichi;
- Shimano, Hitoshi;
- Katayama, Shigehiro;
- Ohashi, Yasuo
Publication type:
journal article
A subtype of diabetes mellitus associated with a mutation in the mitochondrial gene.
Published in:
Muscle & Nerve, 1995, v. 18, n. S14, p. S137, doi. 10.1002/mus.880181427
By:
- Kadowaki, T.;
- Sakura, H.;
- Otabe, S.;
- Yasuda, K.;
- Kadowaki, H.;
- Mori, Y.;
- Hagura, R.;
- Akanuma, Y.;
- Yazaki, Y.
Publication type:
Article
Prevalence of major vascular complications at the initial visit among Japanese diabetic patients.
Published in:
1979
By:
- Miki, Eishi;
- Akanuma, Yasuo;
- Kanazawa, Yasunori;
- Sando, Hiroyuki;
- Kikuchi, Masatoshi;
- Kawazu, Shoji;
- Kosa, Kinori;
- Miki, E;
- Akanuma, Y;
- Kanazawa, Y;
- Sando, H;
- Kikuchi, M;
- Kawazu, S;
- Kosaka, K
Publication type:
journal article

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