Works by Akahane, Toshiaki

Results: 37

Heterochronic pelvic high-grade myxoinflammatory fibroblastic sarcoma and uterine endometroid carcinoma harboring common gene mutations: a rare case report with genomic analysis.

Published in:

Diagnostic Pathology, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13000-025-01669-4

By:

Higashi, Yuriko;
Mizuno, Mika;
Kitazono, Ikumi;
Akahane, Toshiaki;
Tasaki, Takashi;
Noguchi, Hirotsugu;
Hisaoka, Masanori;
Kobayashi, Hiroaki;
Tanimoto, Akihide

Publication type:

Article

Next‐generation sequencing in residual liquid‐based cytology specimens for cancer genome analysis.

Published in:

Diagnostic Cytopathology, 2020, v. 48, n. 11, p. 965, doi. 10.1002/dc.24511

By:

Yamaguchi, Tomomi;
Akahane, Toshiaki;
Harada, Ohi;
Kato, Yasutaka;
Aimono, Eriko;
Takei, Hidehiro;
Tasaki, Takashi;
Noguchi, Hirotsugu;
Nishihara, Hiroshi;
Kamata, Hajime;
Tanimoto, Akihide

Publication type:

Article

Diagnostic value of liquid-based cytology with fine needle aspiration specimens for cervical lymphadenopathy.

Published in:

Diagnostic Cytopathology, 2016, v. 44, n. 3, p. 169, doi. 10.1002/dc.23402

By:

Bandoh, Nobuyuki;
Goto, Takashi;
Akahane, Toshiaki;
Ohnuki, Natsumi;
Yamaguchi, Tomomi;
Kamada, Hajime;
Harabuchi, Yasuaki;
Tanaka, Shinya;
Nishihara, Hiroshi

Publication type:

Article

Breast cancer with an intraductal component that was proven genetically to be metastasis of contralateral breast cancer: a case report.

Published in:

Surgical Case Reports, 2020, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40792-020-00966-y

By:

Shinden, Yoshiaki;
Saho, Hazuki;
Nomoto, Yuki;
Nagata, Ayako;
Minami, Koji;
Nakajo, Akihiro;
Akahane, Toshiaki;
Hiraki, Tsubasa;
Tanimoto, Akihide;
Owaki, Tetsuhiro;
Kijima, Yuko;
Natsugoe, Shoji

Publication type:

Article

Targeted next-generation sequencing of cancer-related genes in thyroid carcinoma: A single institution's experience.

Published in:

Oncology Letters, 2018, v. 16, n. 6, p. 7278, doi. 10.3892/ol.2018.9538

By:

Bandoh, Nobuyuki;
Akahane, Toshiaki;
Goto, Takashi;
Kono, Michihisa;
Ichikawa, Haruyuki;
Sawada, Takahiro;
Yamaguchi, Tomomi;
Nakano, Hiroshi;
Kawase, Yumiko;
Kato, Yasutaka;
Kamada, Hajime;
Harabuchi, Yasuaki;
Shimizu, Kazuo;
Nishihara, Hiroshi

Publication type:

Article

Monocyte chemoattractant protein 1 expression and proliferation in primary central nervous system lymphoma.

Published in:

Oncology Letters, 2017, v. 14, n. 1, p. 264, doi. 10.3892/ol.2017.6122

By:

HAJIME KAMADA;
YOSHINOBU TAKAHASHI;
TAKAHIRO SAWADA;
YUMIKO KAWASE;
TOSHIAKI AKAHANE;
HIDETOSHI IKEDA;
KEISHI MAKINO;
HIDEO NAKAMURA;
TAKUICHIRO HIDE;
SHIGETOSHI YANO;
NAOYA HASHIMOTO

Publication type:

Article

An oncogenic splice variant of PDGFRα in adult glioblastoma as a therapeutic target for selective CDK4/6 inhibitors.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-05391-9

By:

Hamada, Taiji;
Akahane, Toshiaki;
Yokoyama, Seiya;
Higa, Nayuta;
Kirishima, Mari;
Matsuo, Kei;
Shimokawa, Michiko;
Yoshimoto, Koji;
Tanimoto, Akihide

Publication type:

Article

Next-generation sequencing analysis of endometrial screening liquid-based cytology specimens: a comparative study to tissue specimens.

Published in:

BMC Medical Genomics, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s12920-020-00753-6

By:

Akahane, Toshiaki;
Kitazono, Ikumi;
Yanazume, Shintaro;
Kamio, Masaki;
Togami, Shinichi;
Sakamoto, Ippei;
Nohara, Sachio;
Yokoyama, Seiya;
Kobayashi, Hiroaki;
Hiraki, Tsubasa;
Suzuki, Shinsuke;
Ueno, Shinichi;
Tanimoto, Akihide

Publication type:

Article

Cancer gene analysis of liquid‐based cytology specimens using next‐generation sequencing: A technical report of bimodal DNA‐ and RNA‐based panel application.

Published in:

Diagnostic Cytopathology, 2023, v. 51, n. 8, p. 493, doi. 10.1002/dc.25149

By:

Akahane, Toshiaki;
Isochi‐Yamaguchi, Tomomi;
Hashiba‐Ohnuki, Natumi;
Bandoh, Nobuyuki;
Aimono, Eriko;
Kato, Yasutaka;
Nishihara, Hiroshi;
Kamada, Hajime;
Tanimoto, Akihide

Publication type:

Article

Sequential evaluation of MUC promoter methylation using next‐generation sequencing‐based custom‐made panels in liquid‐based cytology specimens of pancreatic cancer.

Published in:

Diagnostic Cytopathology, 2022, v. 50, n. 11, p. 499, doi. 10.1002/dc.25022

By:

Yokoyama, Sieya;
Iwaya, Hiromichi;
Akahane, Toshiaki;
Hamada, Taiji;
Higashi, Michiyo;
Hashimoto, Shinichi;
Tanoue, Shiroh;
Ohtsuka, Takao;
Ido, Akio;
Tanimoto, Akihide

Publication type:

Article

Direct next‐generation sequencing analysis using endometrial liquid‐based cytology specimens for rapid cancer genomic profiling.

Published in:

Diagnostic Cytopathology, 2021, v. 49, n. 9, p. 1078, doi. 10.1002/dc.24841

By:

Akahane, Toshiaki;
Kitazono, Ikumi;
Kobayashi, Yusuke;
Nishida‐Kirita, Yukari;
Yamaguchi, Tomomi;
Yanazume, Shintaro;
Tabata, Kazuhiro;
Kobayashi, Hiroaki;
Tanimoto, Akihide

Publication type:

Article

Cervical Cytology Preserves Histologically Detected Surface Epithelial Slackening, Unique to the POLE Mutation-subtype in Endometrial Cancer.

Published in:

In Vivo, 2024, v. 38, n. 1, p. 321, doi. 10.21873/invivo.13442

By:

IKUMI KITAZONO;
TOSHIAKI AKAHANE;
SEIYA YOKOYAMA;
EMI KUBOTA;
YUKARI NISHIDA-KIRITA;
HIROTSUGU NOGUCHI;
MIKI MURAKAMI;
SHINTARO YANAZUME;
HIROAKI KOBAYASHI;
AKIHIDE TANIMOTO

Publication type:

Article

Alterations in EGFR and PDGFRA are associated with the localization of contrast-enhancing lesions in glioblastoma.

Published in:

Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad110

By:

Makino, Ryutaro;
Higa, Nayuta;
Akahane, Toshiaki;
Yonezawa, Hajime;
Uchida, Hiroyuki;
Takajo, Tomoko;
Fujio, Shingo;
Kirishima, Mari;
Hamada, Taiji;
Yamahata, Hitoshi;
Kamimura, Kiyohisa;
Yoshiura, Takashi;
Yoshimoto, Koji;
Tanimoto, Akihide;
Hanaya, Ryosuke

Publication type:

Article

Favorable prognostic impact of phosphatase and tensin homolog alterations in wild-type isocitrate dehydrogenase and telomerase reverse transcriptase promoter glioblastoma.

Published in:

Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad078

By:

Higa, Nayuta;
Akahane, Toshiaki;
Yokoyama, Seiya;
Makino, Ryutaro;
Yonezawa, Hajime;
Uchida, Hiroyuki;
Takajo, Tomoko;
Kirishima, Mari;
Hamada, Taiji;
Noguchi, Naoki;
Otsuji, Ryosuke;
Kuga, Daisuke;
Nagasaka, Shohei;
Yamahata, Hitoshi;
Yamamoto, Junkoh;
Yoshimoto, Koji;
Tanimoto, Akihide;
Hanaya, Ryosuke

Publication type:

Article

Prognostic impact of PDGFRA gain/amplification and MGMT promoter methylation status in patients with IDH wild-type glioblastoma.

Published in:

Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac097

By:

Nayuta Higa;
Toshiaki Akahane;
Seiya Yokoyama;
Hajime Yonezawa;
Hiroyuki Uchida;
Tomoko Takajo;
Ryosuke Otsuji;
Taiji Hamada;
Kei Matsuo;
Mari Kirishima;
Nobuhiro Hata;
Ryosuke Hanaya;
Akihide Tanimoto;
Koji Yoshimoto

Publication type:

Article

MALAT1 functions as a transcriptional promoter of MALAT1::GLI1 fusion for truncated GLI1 protein expression in cancer.

Published in:

BMC Cancer, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12885-023-10867-6

By:

Hamada, Taiji;
Higashi, Michiyo;
Yokoyama, Seiya;
Akahane, Toshiaki;
Hisaoka, Masanori;
Noguchi, Hirotsugu;
Furukawa, Tatsuhiko;
Tanimoto, Akihide

Publication type:

Article

A tailored next‐generation sequencing panel identified distinct subtypes of wildtype IDH and TERT promoter glioblastomas.

Published in:

Cancer Science, 2020, v. 111, n. 10, p. 3902, doi. 10.1111/cas.14597

By:

Higa, Nayuta;
Akahane, Toshiaki;
Yokoyama, Seiya;
Yonezawa, Hajime;
Uchida, Hiroyuki;
Takajo, Tomoko;
Kirishima, Mari;
Hamada, Taiji;
Matsuo, Kei;
Fujio, Shingo;
Hanada, Tomoko;
Hosoyama, Hiroshi;
Yonenaga, Masanori;
Sakamoto, Akihisa;
Hiraki, Tsubasa;
Tanimoto, Akihide;
Yoshimoto, Koji

Publication type:

Article

Integrated diagnosis of adult‐type glioma according to 2021 World Health Organization classification: Analysis of 184 cases using a custom‐made next‐generation sequencing panel.

Published in:

Pathology International, 2022, v. 72, n. 3, p. 207, doi. 10.1111/pin.13197

By:

Kirishima, Mari;
Akahane, Toshiaki;
Higa, Nayuta;
Yonezawa, Hajime;
Uchida, Hiroyuki;
Kitazono, Ikumi;
Higashi, Michiyo;
Yoshimoto, Koji;
Tanimoto, Akihide

Publication type:

Article

The Japanese Society of Pathology Guidelines on the handling of pathological tissue samples for genomic research: Standard operating procedures based on empirical analyses.

Published in:

Pathology International, 2018, v. 68, n. 2, p. 63, doi. 10.1111/pin.12631

By:

Kanai, Yae;
Nishihara, Hiroshi;
Miyagi, Yohei;
Tsuruyama, Tatsuhiro;
Taguchi, Kenichi;
Katoh, Hiroto;
Takeuchi, Tomoyo;
Gotoh, Masahiro;
Kuramoto, Junko;
Arai, Eri;
Ojima, Hidenori;
Shibuya, Ayako;
Yoshida, Teruhiko;
Akahane, Toshiaki;
Kasajima, Rika;
Morita, Kei‐ichi;
Inazawa, Johji;
Sasaki, Takeshi;
Fukayama, Masashi;
Oda, Yoshinao

Publication type:

Article

Adult classical glioblastoma with a BRAF V600E mutation.

Published in:

World Journal of Surgical Oncology, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12957-015-0521-x

By:

Yoshinobu Takahashi;
Toshiaki Akahane;
Takahiro Sawada;
Hidetoshi Ikeda;
Akira Tempaku;
Shigeru Yamauchi;
Hiroshi Nishihara;
Shinya Tanaka;
Kazumi Nitta;
Wataru Ide;
Ikuo Hashimoto;
Hajime Kamada

Publication type:

Article

Comparison of actionable alterations in cancers with kinase fusion, mutation, and copy number alteration.

Published in:

PLoS ONE, 2025, v. 19, n. 1, p. 1, doi. 10.1371/journal.pone.0305025

By:

Suzuki, Shinsuke;
Akahane, Toshiaki;
Tanimoto, Akihide;
Higashi, Michiyo;
Kitazono, Ikumi;
Kirishima, Mari;
Nishigaki, Masakazu;
Ikeda, Toshiro;
Kanemitsu, Shuichi;
Nakazawa, Junichi;
Akahane, Erina;
Nishihara, Hiroshi;
Uozumi, Kimiharu;
Yoshimitsu, Makoto;
Ishitsuka, Kenji;
Ueno, Shin-ichi

Publication type:

Article

Distribution and favorable prognostic implication of genomic EGFR alterations in IDH‐wildtype glioblastoma.

Published in:

Cancer Medicine, 2023, v. 12, n. 1, p. 49, doi. 10.1002/cam4.4939

By:

Higa, Nayuta;
Akahane, Toshiaki;
Hamada, Taiji;
Yonezawa, Hajime;
Uchida, Hiroyuki;
Makino, Ryutaro;
Watanabe, Shoji;
Takajo, Tomoko;
Yokoyama, Seiya;
Kirishima, Mari;
Matsuo, Kei;
Fujio, Shingo;
Hanaya, Ryosuke;
Tanimoto, Akihide;
Yoshimoto, Koji

Publication type:

Article

Importance of EQA/PT for the detection of genetic variants in comprehensive cancer genome testing.

Published in:

Scientific Reports, 2025, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-84714-4

By:

Matsushita, Kazuyuki;
Ishige, Takayuki;
Watanabe, Kousuke;
Akahane, Toshiaki;
Tanimoto, Akihide;
Yoshimoto, Michiko;
Yamakuchi, Munekazu;
Hashiguchi, Teruto;
Okugawa, Yoshinaga;
Ikejiri, Makoto;
Yamaguchi, Toshikazu;
Yamasaki, Tadashi;
Takeda, Mayu;
Hibi, Masaaki;
Akiyama, Naoki;
Shimizu, Kaho;
Hashimoto, Naonori;
Sato, Hiroko;
Tanaka, Yoshinori;
Amari, Fumie

Publication type:

Article

Prognosis prediction via histological evaluation of cellular heterogeneity in glioblastoma.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-76826-8

By:

Kirishima, Mari;
Yokoyama, Seiya;
Akahane, Toshiaki;
Higa, Nayuta;
Uchida, Hiroyuki;
Yonezawa, Hajime;
Matsuo, Kei;
Yamamoto, Junkoh;
Yoshimoto, Koji;
Hanaya, Ryosuke;
Tanimoto, Akihide

Publication type:

Article

Cytopathological features associated with POLE mutation in endometrial cancer.

Published in:

Cytopathology, 2023, v. 34, n. 3, p. 211, doi. 10.1111/cyt.13215

By:

Yanazume, Shintaro;
Iwakiri, Kaori;
Kobayashi, Yusuke;
Kitazono, Ikumi;
Akahane, Toshiaki;
Mizuno, Mika;
Togami, Shinichi;
Tanimoto, Akihide;
Kobayashi, Hiroaki

Publication type:

Article

Glutaminolysis is associated with mitochondrial pathway activation and can be therapeutically targeted in glioblastoma.

Published in:

Cancer & Metabolism, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40170-024-00364-0

By:

Miki, Kenji;
Yagi, Mikako;
Hatae, Ryusuke;
Otsuji, Ryosuke;
Miyazaki, Takahiro;
Goto, Katsuhiro;
Setoyama, Daiki;
Fujioka, Yutaka;
Sangatsuda, Yuhei;
Kuga, Daisuke;
Higa, Nayuta;
Takajo, Tomoko;
Hajime, Yonezawa;
Akahane, Toshiaki;
Tanimoto, Akihide;
Hanaya, Ryosuke;
Kunisaki, Yuya;
Uchiumi, Takeshi;
Yoshimoto, Koji

Publication type:

Article

Next-Generation Sequencing Analysis of Pancreatic Cancer Using Residual Liquid Cytology Specimens from Endoscopic Ultrasound—Guided Fine-Needle Biopsy: A Prospective Comparative Study with Tissue Specimens.

Published in:

Diagnostics (2075-4418), 2023, v. 13, n. 6, p. 1078, doi. 10.3390/diagnostics13061078

By:

Iwaya, Hiromichi;
Tanimoto, Akihide;
Toyodome, Koshiro;
Kojima, Issei;
Hinokuchi, Makoto;
Tanoue, Shiroh;
Hashimoto, Shinichi;
Kawahira, Machiko;
Arima, Shiho;
Kanmura, Shuji;
Akahane, Toshiaki;
Higashi, Michiyo;
Suzuki, Shinsuke;
Ueno, Shinichi;
Ohtsuka, Takao;
Ido, Akio

Publication type:

Article

Comprehensive validation of liquid-based cytology specimens for next-generation sequencing in cancer genome analysis.

Published in:

PLoS ONE, 2019, v. 14, n. 6, p. 1, doi. 10.1371/journal.pone.0217724

By:

Akahane, Toshiaki;
Yamaguchi, Tomomi;
Kato, Yasutaka;
Yokoyama, Seiya;
Hamada, Taiji;
Nishida, Yukari;
Higashi, Michiyo;
Nishihara, Hiroshi;
Suzuki, Shinsuke;
Ueno, Shinichi;
Tanimoto, Akihide

Publication type:

Article

Genome Editing Using Cas9 Ribonucleoprotein Is Effective for Introducing PDGFRA Variant in Cultured Human Glioblastoma Cell Lines.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 500, doi. 10.3390/ijms24010500

By:

Hamada, Taiji;
Yokoyama, Seiya;
Akahane, Toshiaki;
Matsuo, Kei;
Tanimoto, Akihide

Publication type:

Article

Gallbladder microbiota composition is associated with pancreaticobiliary and gallbladder cancer prognosis.

Published in:

BMC Microbiology, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12866-022-02557-3

By:

Kirishima, Mari;
Yokoyama, Seiya;
Matsuo, Kei;
Hamada, Taiji;
Shimokawa, Michiko;
Akahane, Toshiaki;
Sugimoto, Tomoyuki;
Tsurumaru, Hirohito;
Ishibashi, Matsujiro;
Mataki, Yuko;
Ootsuka, Takao;
Nomoto, Mitsuharu;
Hayashi, Chihiro;
Horiguchi, Akihiko;
Higashi, Michiyo;
Tanimoto, Akihide

Publication type:

Article

An oncogenic splice variant of PDGFRα in adult glioblastoma as a therapeutic target for selective CDK4/6 inhibitors.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-05391-9

By:

Hamada, Taiji;
Akahane, Toshiaki;
Yokoyama, Seiya;
Higa, Nayuta;
Kirishima, Mari;
Matsuo, Kei;
Shimokawa, Michiko;
Yoshimoto, Koji;
Tanimoto, Akihide

Publication type:

Article

Electroporation Induces Unexpected Alterations in Gene Expression: A Tip for Selection of Optimal Transfection Method.

Published in:

Current Issues in Molecular Biology, 2025, v. 47, n. 2, p. 91, doi. 10.3390/cimb47020091

By:

Hamada, Taiji;
Yokoyama, Seiya;
Akahane, Toshiaki;
Matsuo, Kei;
Kitazono, Ikumi;
Furukawa, Tatsuhiko;
Tanimoto, Akihide

Publication type:

Article

Pelvic Carcinosarcoma Showing a Diverse Histology and Hierarchical Gene Mutation with a Common POLE Mutation to Endometrial Endometroid Carcinoma: A Case Report.

Published in:

International Journal of Surgical Pathology, 2022, v. 30, n. 8, p. 891, doi. 10.1177/10668969221088880

By:

Kitazono, Ikumi;
Akahane, Toshiaki;
Kobayashi, Yusuke;
Yanazume, Shintaro;
Tabata, Kazuhiro;
Tasaki, Takashi;
Noguchi, Hirotsugu;
Kirishima, Mari;
Higashi, Michiyo;
Kobayashi, Hiroaki;
Tanimoto, Akihide

Publication type:

Article

Two Components of Variant Profiles in Primary Vaginal Carcinosarcoma via Next-Generation Sequencing and a Literature Review.

Published in:

International Journal of Surgical Pathology, 2022, v. 30, n. 3, p. 288, doi. 10.1177/10668969211037915

By:

Kotoku, Rakan;
Yanazume, Shintaro;
Kuroda, Takafumi;
Kobayashi, Yusuke;
Kitazono, Ikumi;
Akahane, Toshiaki;
Tanimoto, Akihide;
Kobayashi, Hiroaki

Publication type:

Article

Human Papilloma Virus 18-Positive Submucosal Small Cell Neuroendocrine Carcinoma of the Vagina: An Immunohistochemical and Genomic Study.

Published in:

International Journal of Surgical Pathology, 2021, v. 29, n. 8, p. 870, doi. 10.1177/10668969211007569

By:

Kitazono, Ikumi;
Akahane, Toshiaki;
Sakihama, Mika;
Yanazume, Shintaro;
Matsushita, Michiko;
Tabata, Kazuhiro;
Kobayashi, Yusuke;
Kobayashi, Hiroaki;
Umekita, Yoshihisa;
Tanimoto, Akihide

Publication type:

Article

Targeted next-generation sequencing assays using triplet samples of normal breast tissue, primary breast cancer, and recurrent/metastatic lesions.

Published in:

2020

By:

Akahane, Toshiaki;
Kanomata, Naoki;
Harada, Oi;
Yamashita, Tetsumasa;
Kurebayashi, Junichi;
Tanimoto, Akihide;
Moriya, Takuya

Publication type:

journal article

Can Endometrial Cytology Identify Patients Who Would Benefit from Immunotherapy?

Published in:

Acta Cytologica, 2024, v. 68, n. 2, p. 128, doi. 10.1159/000538288

By:

Yanazume, Shintaro;
Kirita, Yukari;
Kobayashi, Yusuke;
Kitazono, Ikumi;
Akahane, Toshiaki;
Mizuno, Mika;
Togami, Shinichi;
Tanimoto, Akihide;
Kobayashi, Hiroaki

Publication type:

Article