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A Review on Drug‐Induced Nephrotoxicity: Pathophysiological Mechanisms, Drug Classes, Clinical Management, and Recent Advances in Mathematical Modeling and Simulation Approaches.
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- Clinical Pharmacology in Drug Development, 2020, v. 9, n. 8, p. 896, doi. 10.1002/cpdd.879
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- Article
Application of Pharmacokinetic and Pharmacodynamic Analysis to the Development of Liposomal Formulations for Oncology.
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- Pharmaceutics, 2014, v. 6, n. 1, p. 137, doi. 10.3390/pharmaceutics6010137
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- Article
In vitro to clinical translational pharmacokinetic/pharmacodynamic modeling of doxorubicin (DOX) and dexrazoxane (DEX) interactions: Safety assessment and optimization.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-29964-4
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- Article
Development and Evaluation of Tri-Functional Immunoliposomes for the Treatment of HER2 Positive Breast Cancer.
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- Pharmaceutical Research, 2018, v. 35, n. 5, p. N.PAG, doi. 10.1007/s11095-018-2365-x
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- Article
Non-linear mixed effect modeling of the time-variant disposition of erythropoietin in anemic cancer patients.
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- Biopharmaceutics & Drug Disposition, 2011, v. 32, n. 1, p. 1, doi. 10.1002/bdd.733
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- Article
Multiscale and Translational Quantitative Systems Toxicology, Pharmacokinetic-Toxicodynamic Modeling Analysis for Assessment of Doxorubicin-Induced Cardiotoxicity.
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- AAPS Journal, 2021, v. 23, n. 1, p. 1, doi. 10.1208/s12248-020-00542-0
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- Article
A Mechanism-Based PK/PD Model for Hematological Toxicities Induced by Antibody-Drug Conjugates.
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- AAPS Journal, 2017, v. 19, n. 5, p. 1436, doi. 10.1208/s12248-017-0113-5
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- Article
In vitro to Clinical Translation of Combinatorial Effects of Doxorubicin and Abemaciclib in Rb-Positive Triple Negative Breast Cancer: A Systems-Based Pharmacokinetic/Pharmacodynamic Modeling Approach.
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- Breast Cancer: Targets & Therapy, 2021, v. 13, p. 87, doi. 10.2147/BCTT.S292161
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- Article
Chloroquine sensitizes MDA-MB-231 cells to osimertinib through autophagy–apoptosis crosstalk pathway.
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- Breast Cancer: Targets & Therapy, 2019, v. 11, p. 231, doi. 10.2147/BCTT.S211030
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- Article
Current advances in biomarkers for targeted therapy in triple-negative breast cancer.
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- Breast Cancer: Targets & Therapy, 2016, v. 8, p. 183, doi. 10.2147/BCTT.S114659
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- Article
Advancing Cancer Therapy with Present and emerging immuno-Oncology Approaches.
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- Frontiers in Oncology, 2017, v. 7, p. 1, doi. 10.3389/fonc.2017.00064
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- Article
Dosing Strategies and Quantitative Clinical Pharmacology for Bispecific T‐Cell Engagers Development in Oncology.
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- Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 3, p. 637, doi. 10.1002/cpt.3361
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- Article
Subcutaneous Biologics: Clinical Pharmacology and Drug Development.
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- Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 3, p. 385, doi. 10.1002/cpt.3179
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- Article
Challenging the Norm: A Multidisciplinary Perspective on Intravenous to Subcutaneous Bridging Strategies for Biologics.
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- Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 3, p. 412, doi. 10.1002/cpt.3133
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- Article
The Impact of Immunogenicity on the Pharmacokinetics, Efficacy, and Safety of Sotatercept in a Phase III Study of Pulmonary Arterial Hypertension.
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- Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 3, p. 478, doi. 10.1002/cpt.3116
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- Article
Population pharmacokinetic modeling of sotatercept in healthy participants and patients with pulmonary arterial hypertension.
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- CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 8, p. 1380, doi. 10.1002/psp4.13166
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- Article
Population pharmacokinetic analysis of the P2X3‐receptor antagonist gefapixant.
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- CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 8, p. 1107, doi. 10.1002/psp4.12978
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- Article
Utility of a Novel Three-Dimensional and Dynamic (3DD) Cell Culture System for PK/PD Studies: Evaluation of a Triple Combination Therapy at Overcoming Anti-HER2 Treatment Resistance in Breast Cancer.
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- Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00403
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- Article
Fourteenth American Conference on Pharmacometrics (ACoP14) – Innovation and Diversity: Redefining Pharmacometrics.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2024, v. 51, n. 2, p. 95, doi. 10.1007/s10928-024-09908-9
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- Article
Correction to: Training the next generation of pharmacometric modelers: a multisector perspective.
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- 2024
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- Correction Notice
Training the next generation of pharmacometric modelers: a multisector perspective.
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- 2024
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- Publication type:
- Letter
International society of Pharmacometrics Mentorship Program (IMP): feedback survey from the first cohort of mentor-mentee pairs.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2023, v. 50, n. 4, p. 243, doi. 10.1007/s10928-023-09880-w
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- Article
Knowledge dissemination and central indexing of resources in pharmacometrics: an ISOP education working group initiative.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2022, v. 49, n. 4, p. 397, doi. 10.1007/s10928-022-09809-9
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- Article
Experimental and computational assessment of the synergistic pharmacodynamic drug–drug interactions of a triple combination therapy in refractory HER2-positive breast cancer cells.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2022, v. 49, n. 2, p. 227, doi. 10.1007/s10928-021-09795-4
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- Article
A quantitative systems pharmacological approach identified activation of JNK signaling pathway as a promising treatment strategy for refractory HER2 positive breast cancer.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2021, v. 48, n. 2, p. 273, doi. 10.1007/s10928-020-09732-x
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- Article
Multiscale systems pharmacological analysis of everolimus action in hepatocellular carcinoma.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2018, v. 45, n. 4, p. 607, doi. 10.1007/s10928-018-9590-0
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- Article
Systems pharmacological analysis of mitochondrial cardiotoxicity induced by selected tyrosine kinase inhibitors.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2018, v. 45, n. 3, p. 401, doi. 10.1007/s10928-018-9578-9
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- Article
Array of translational systems pharmacodynamic models of anti-cancer drugs.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2016, v. 43, n. 6, p. 549, doi. 10.1007/s10928-016-9497-6
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- Article
Pharmacodynamic Modeling to Evaluate the Impact of Cimetidine, an OCT2 Inhibitor, on the Anticancer Effects of Cisplatin.
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- Cells (2073-4409), 2023, v. 12, n. 1, p. 57, doi. 10.3390/cells12010057
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- Article
In vitro to clinical translation of combinatorial effects of doxorubicin and dexrazoxane in breast cancer: a mechanism-based pharmacokinetic/pharmacodynamic modeling approach.
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- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1239141
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- Article
Pharmacodynamic Modeling of Cell Cycle Effects for Gemcitabine and Trabectedin Combinations in Pancreatic Cancer Cells.
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- Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00421
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- Article
Evaluating the Clinical Impact of Formulation Variability: A Metoprolol Extended‐Release Case Study.
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- Journal of Clinical Pharmacology, 2019, v. 59, n. 9, p. 1266, doi. 10.1002/jcph.1433
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- Article
Pharmacodynamic Modeling Identifies Synergistic Interaction Between Chloroquine and Trastuzumab in Refractory HER2- positive Breast Cancer Cells.
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- Cancer Diagnosis & Prognosis, 2023, v. 3, n. 2, p. 175, doi. 10.21873/cdp.10198
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- Article
Mechanisms, monitoring, and management of tyrosine kinase inhibitors-associated cardiovascular toxicities.
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- OncoTargets & Therapy, 2018, v. 11, p. 6227, doi. 10.2147/OTT.S170138
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- Article
Understanding the role of PD-L1/PD1 pathway blockade and autophagy in cancer therapy.
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- OncoTargets & Therapy, 2017, v. 10, p. 1803, doi. 10.2147/OTT.S132508
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- Article
Erythropoietin-Induced Erythroid Precursor Pool Depletion Causes Erythropoietin Hyporesponsiveness.
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- Pharmaceutical Research, 2013, v. 30, n. 4, p. 1026, doi. 10.1007/s11095-012-0938-7
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- Article
Meta-analysis of Nanoparticulate Paclitaxel Delivery System Pharmacokinetics and Model Prediction of Associated Neutropenia.
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- Pharmaceutical Research, 2012, v. 29, n. 10, p. 2833, doi. 10.1007/s11095-012-0775-8
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- Article