Works by Aimin Zang

Results: 32

CRISPR/Cas9-induced saturated mutagenesis identifies Rad51 haplotype as a marker of PARP inhibitor sensitivity in breast cancer.

Published in:

Molecular Medicine Reports, 2022, v. 26, n. 2, p. N.PAG, doi. 10.3892/mmr.2022.12774

By:

Yang, Hua;
Wei, Yaning;
Zhang, Qian;
Yang, Yang;
Bi, Xuebing;
Yang, Lin;
Xiao, Na;
Zang, Aimin;
Ren, Lili;
Li, Xiaoli

Publication type:

Article

Triptolide reduces proliferation and enhances apoptosis of human non-small cell lung cancer cells through PTEN by targeting miR-21.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 3, p. 2763, doi. 10.3892/mmr.2016.4844

By:

XIAOFANG LI;
AIMIN ZANG;
YOUCHAO JIA;
JINCHAO ZHANG;
WUFANG FAN;
JIA FENG;
MINDAN DUAN;
LEI ZHANG;
RAN HUO;
JIN JIAO;
XIAOWEI ZHU

Publication type:

Article

microRNA-425-5p is upregulated in human gastric cancer and contributes to invasion and metastasis in vitro and in vivo.

Published in:

Experimental & Therapeutic Medicine, 2015, v. 9, n. 5, p. 1617, doi. 10.3892/etm.2015.2318

By:

ZHUOQI ZHANG;
YONG LI;
LIQIAO FAN;
QUN ZHAO;
BIBO TAN;
ZHONG LI;
AIMIN ZANG

Publication type:

Article

Clinical Activity and Safety of Penpulimab (Anti-PD-1) With Anlotinib as First-Line Therapy for Unresectable Hepatocellular Carcinoma: An Open-Label, Multicenter, Phase Ib/II Trial (AK105-203).

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.684867

By:

Han, Chun;
Ye, Sisi;
Hu, Chunhong;
Shen, Liangfang;
Qin, Qun;
Bai, Yuxian;
Yang, Shizhong;
Bai, Chunmei;
Zang, Aimin;
Jiao, Shunchang;
Bai, Li

Publication type:

Article

MicroRNA-146a rs2910164 polymorphism is associated with susceptibility to non-small cell lung cancer in the Chinese population.

Published in:

Medical Oncology, 2014, v. 31, n. 10, p. 1, doi. 10.1007/s12032-014-0194-2

By:

Jia, Youchao;
Zang, Aimin;
Shang, Yanhong;
Yang, Hua;
Song, Zizheng;
Wang, Zhiyu;
Ren, Lili;
Wei, Yaning;
Hu, Ling;
Shi, Hongyun;
Li, Hefei

Publication type:

Article

SEMA3D Plays a Critical Role in Peptic Ulcer Disease-Related Carcinogenesis Induced by H. pylori Infection.

Published in:

International Journal of General Medicine, 2022, v. 15, p. 1239, doi. 10.2147/IJGM.S343635

By:

Wang, Zhiyu;
Wei, Yaning;
An, lin;
Wang, Kunjie;
Hong, Dan;
Shi, Yan;
Zang, Aimin;
Su, Shenyong;
Li, Wenwen

Publication type:

Article

Identification of a novel prognosis-associated ceRNA network in lung adenocarcinoma via bioinformatics analysis.

Published in:

2021

By:

Li, Yumiao;
Yu, Xiaoxue;
Zhang, Yuhao;
Wang, Xiaofang;
Zhao, Linshan;
Liu, Dan;
Zhao, Guofa;
Gao, Xiangpeng;
Fu, Jiejun;
Zang, Aimin;
Jia, Youchao

Publication type:

journal article

Elevation of microRNA-365 impedes malignant behaviors of gastric cancer cells by inhibiting PAX6.

Published in:

Functional & Integrative Genomics, 2022, v. 22, n. 5, p. 825, doi. 10.1007/s10142-022-00858-4

By:

Hong, Dan;
Zang, Aimin;
Wang, Zhiyu;
Yang, Lin;
Ren, Guanying;
Zhang, Chong;
Zhang, Liwei;
Hou, Wei;
Wei, Yaning

Publication type:

Article

Tetramethylpyrazine inhibits tumor growth of lung cancer through disrupting angiogenesis via BMP/Smad/Id-1 signaling.

Published in:

International Journal of Oncology, 2016, v. 48, n. 5, p. 2079, doi. 10.3892/ijo.2016.3443

By:

YOUCHAO JIA;
ZHIGANG WANG;
AIMIN ZANG;
SHUNCHANG JIAO;
SUMEI CHEN;
YAN FU

Publication type:

Article

Hyaluronic Acid Capped, Irinotecan and Gene Co-Loaded Lipid-Polymer Hybrid Nanocarrier-Based Combination Therapy Platform for Colorectal Cancer.

Published in:

Drug Design, Development & Therapy, 2020, v. 14, p. 1095, doi. 10.2147/DDDT.S230306

By:

Wang, Zhiyu;
Zang, Aimin;
Wei, Yaning;
An, Lin;
Hong, Dan;
Shi, Yan;
Zhang, Jingnan;
Su, Shenyong;
Fang, Guotao

Publication type:

Article

Colorectal cancer combination therapy using drug and gene co-delivered, targeted poly(ethylene glycol)-ε-poly(caprolactone) nanocarriers.

Published in:

Drug Design, Development & Therapy, 2018, v. 12, p. 3171, doi. 10.2147/DDDT.S175614

By:

Wang, Zhiyu;
Wei, Yaning;
Fang, Guotao;
Hong, Dan;
An, Lin;
Jiao, Ting;
Shi, Yan;
Zang, Aimin

Publication type:

Article

LGR5 Is a Gastric Cancer Stem Cell Marker Associated with Stemness and the EMT Signature Genes NANOG, NANOGP8, PRRX1, TWIST1, and BMI1.

Published in:

PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0168904

By:

Wang, Bei;
Chen, Queting;
Cao, Yang;
Ma, Xia;
Yin, Chenxing;
Jia, Youchao;
Zang, Aimin;
Fan, Wufang

Publication type:

Article

miRNA-486 and miRNA-499 in human plasma evaluate the clinical stages of lung cancer and play a role as a tumor suppressor in lung tumorigeneisis not pathogenesis.

Published in:

Bangladesh Journal of Pharmacology, 2016, v. 11, n. 1, p. 264, doi. 10.3329/bjp.v11i1.25318

By:

Youchao Jia;
Aimin Zang;
Yanguang Feng;
Xiao-Fang Li;
Ke Zhang;
Hefei Li;
Ruiyao;
3;
Yaning Wei;
Ran Huo

Publication type:

Article

An open label, multicenter, noninterventional study of apatinib in advanced gastric cancer patients (AHEAD-G202).

Published in:

Therapeutic Advances in Medical Oncology, 2020, v. 12, p. 1, doi. 10.1177/1758835920905424

By:

Wang, Xiang;
Zhang, Ruixing;
Du, Nan;
Yang, Mudan;
Zang, Aimin;
Liu, Likun;
Yu, Junyan;
Gao, Jinghua;
Zhang, Junping;
Fu, Zhanzhao;
Ren, Yuchuan;
Ma, Liwen;
Guo, Jun;
Li, Qingshan;
Li, Xiaomei;
Fan, Zaiwen;
Song, Xiang;
Liu, Zheng;
Zhang, Yan;
Li, Guozhong

Publication type:

Article

miR-183 Enhances Autophagy of GC Cells by Targeted Inhibition of mTOR.

Published in:

Annals of Clinical & Laboratory Science, 2021, v. 51, n. 6, p. 837

By:

Yaning Wei;
Dan Hong;
Aimin Zang;
Zhiyu Wang;
Hua Yang;
Pei Zhang;
Yanan Wang

Publication type:

Article

Effect of apatinib combined with chemotherapy on quality of life and related complications in patients with advanced gastric cancer.

Published in:

Tropical Journal of Pharmaceutical Research, 2021, v. 20, n. 8, p. 1715, doi. 10.4314/tjpr.v20i8.24

By:

Dan Hong;
Yaning Wei;
Aimin Zang;
Zhiyu Wang;
Lin Yang;
Guanying Ren;
Shenyong Su;
Chong Zhang

Publication type:

Article

Phase Ib/II study on the safety, tolerability, and preliminary efficacy of pegylated irinotecan (JK1201I) as second‐line monotherapy for patients with small‐cell lung cancer.

Published in:

Cancer Medicine, 2024, v. 13, n. 17, p. 1, doi. 10.1002/cam4.70059

By:

Long, Jieran;
Li, Xuefei;
Wu, Lin;
Yu, Guohua;
Zang, Aimin;
Zhao, Yanqiu;
Shi, Jinsheng;
Nie, Ligong;
Zhao, Xuan;
Fang, Jian

Publication type:

Article

A phase Ib study evaluating the safety and efficacy of IBI310 plus sintilimab in patients with advanced non‐small‐cell lung cancer who have progressed after anti‐PD‐1/L1 therapy.

Published in:

Cancer Medicine, 2024, v. 13, n. 3, p. 1, doi. 10.1002/cam4.6855

By:

Zhao, Yuguang;
Chen, Xiao;
Yao, Jun;
Long, Jianlin;
Mao, Yong;
Wu, Di;
Zang, Aimin;
Zhao, Jun;
Liu, Ziling;
Meng, Rui;
Chen, Ye;
Luo, Yang;
Guo, Qun;
Li, Li;
Cui, Jiuwei

Publication type:

Article

Utilization of circulating cell-free DNA profiling to guide first-line chemotherapy in advanced lung squamous cell carcinoma.

Published in:

Theranostics, 2021, v. 11, n. 1, p. 257, doi. 10.7150/thno.51243

By:

Tao Jiang;
Liyan Jiang;
Xiaorong Dong;
Kangsheng Gu;
Yueyin Pan;
Qin Shi;
Guojun Zhang;
Huijuan Wang;
Xiaochun Zhang;
Nong Yang;
Yuping Li;
Jianping Xiong;
Tienan Yi;
Min Peng;
Yong Song;
Yun Fan;
Jiuwei Cui;
Gongyan Chen;
Wei Tan;
Aimin Zang

Publication type:

Article

MiR-4766-5p Inhibits The Development And Progression Of Gastric Cancer By Targeting NKAP.

Published in:

OncoTargets & Therapy, 2019, v. 12, p. 8525, doi. 10.2147/OTT.S220234

By:

Wei, Yaning;
Wang, Yanan;
Zang, Aimin;
Wang, Zhiyu;
Fang, Guotao;
Hong, Dan

Publication type:

Article

The interleukin-18 gene promoter -607 A/C polymorphism contributes to non-small-cell lung cancer risk in a Chinese population.

Published in:

OncoTargets & Therapy, 2016, v. 9, p. 1715, doi. 10.2147/OTT.S99581

By:

Youchao Jia;
Aimin Zang;
Shunchang Jiao;
Sumei Chen;
Fu Yan

Publication type:

Article

A pooled analysis of clinical outcome in driver-gene negative non-small cell lung cancer patients with MET overexpression treated with gumarontinib.

Published in:

Therapeutic Advances in Medical Oncology, 2024, p. 1, doi. 10.1177/17588359241264730

By:

Yu, Yongfeng;
Dong, Wen;
Shi, Yanxia;
Wu, Rong;
Yu, Qitao;
Ye, Feng;
Zhou, Chengzhi;
Dong, Xiaorong;
Li, Xingya;
Li, Yongsheng;
Li, Zhen;
Wu, Lin;
Pan, Yueyin;
Shen, Hong;
Wu, Dehua;
Xu, Zhongyuan;
Wu, Jinsheng;
Xu, Nong;
Qin, Yanru;
Zang, Aimin

Publication type:

Article

Paclitaxel liposome for injection (Lipusu) plus cisplatin versus gemcitabine plus cisplatin in the first‐line treatment of locally advanced or metastatic lung squamous cell carcinoma: A multicenter, randomized, open‐label, parallel controlled clinical study

Published in:

Cancer Communications, 2022, v. 42, n. 1, p. 3, doi. 10.1002/cac2.12225

By:

Zhang, Jie;
Pan, Yueyin;
Shi, Qin;
Zhang, Guojun;
Jiang, Liyan;
Dong, Xiaorong;
Gu, Kangsheng;
Wang, Huijuan;
Zhang, Xiaochun;
Yang, Nong;
Li, Yuping;
Xiong, Jianping;
Yi, Tienan;
Peng, Min;
Song, Yong;
Fan, Yun;
Cui, Jiuwei;
Chen, Gongyan;
Tan, Wei;
Zang, Aimin

Publication type:

Article

miR-519 regulates the proliferation of breast cancer cells via targeting human antigen R.

Published in:

Oncology Letters, 2020, v. 19, n. 2, p. 1567, doi. 10.3892/ol.2019.11230

By:

Ren, Lili;
Li, Yong;
Zhao, Qun;
Fan, Liqiao;
Tan, Bibo;
Zang, Aimin;
Yang, Hua

Publication type:

Article

Tanshinone IIA inhibits proliferation and induces apoptosis of human nasopharyngeal carcinoma cells via p53-cyclin B1/CDC2.

Published in:

Oncology Letters, 2019, v. 18, n. 3, p. 3317, doi. 10.3892/ol.2019.10658

By:

Liu, Bin;
Liu, Lixia;
Zang, Aimin;
Song, Zizheng;
Yang, Hua;
Wang, Zhiyu;
Shang, Yanhong;
Ma, Tao;
Zhang, Yonggang

Publication type:

Article

Genistein inhibits A549 human lung cancer cell proliferation via miR-27a and MET signaling.

Published in:

Oncology Letters, 2016, v. 12, n. 3, p. 2189, doi. 10.3892/ol.2016.4817

By:

YANG YANG;
AIMIN ZANG;
YOUCHAO JIA;
YANHONG SHANG;
ZHUOQI ZHANG;
KUN GE;
JINCHAO ZHANG;
WUFANG FAN;
BEI WANG

Publication type:

Article

Comprehensive genomic profile of Chinese lung cancer patients and mutation characteristics of individuals resistant to icotinib/gefitinib.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-76791-y

By:

Shang, Yanhong;
Li, Xiaofang;
Liu, Weiwei;
Shi, Xiaoliang;
Yuan, Shaohua;
Huo, Ran;
Fang, Guotao;
Han, Xiao;
Zhang, Jingnan;
Wang, Kunjie;
Dou, Zhengyue;
Zhang, Yan;
Zang, Aimin;
Zhang, Lin

Publication type:

Article

Efficacy and safety of JMT103 in patients with bone metastases from solid tumors: A randomized Phase Ib clinical trial.

Published in:

International Journal of Cancer, 2025, v. 156, n. 11, p. 2178, doi. 10.1002/ijc.35343

By:

Ran, Ran;
Li, Hongtao;
Sun, Tao;
Zhou, Huan;
Zang, Aimin;
Guo, Hongqian;
Xie, Hua;
Wu, Shikai;
Yan, Yong;
Yin, Xing;
Xiong, Hailin;
Li, Hong;
Yuan, Jing;
Wang, Juan;
Li, Huiping;
Li, Jin

Publication type:

Article

First-in-human study of DP303c, a HER2-targeted antibody-drug conjugate in patients with HER2 positive solid tumors.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00687-7

By:

Zhang, Jian;
Du, Yiqun;
Meng, Yanchun;
Liu, Xiaojun;
Mu, Yuxin;
Liu, Yunpeng;
Shi, Yehui;
Wang, Jufeng;
Zang, Aimin;
Gu, Shanzhi;
Liu, Tianshu;
Zhou, Huan;
Guo, Hongqian;
Xiang, Silong;
Zhang, Xialu;
Wu, Suqiong;
Qi, Huanhuan;
Li, Mengke;
Hu, Xichun

Publication type:

Article

Capivasertib plus fulvestrant in patients with HR-positive/HER2-negative advanced breast cancer: phase 3 CAPItello-291 study extended Chinese cohort.

Published in:

Nature Communications, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41467-025-59210-6

By:

Hu, Xichun;
Zhang, Qingyuan;
Sun, Tao;
Xiong, Huihua;
Li, Wei;
Teng, Yuee;
Lu, Yen-Shen;
Tseng, Ling-Ming;
Yan, Min;
Li, Hongsheng;
Pang, Danmei;
-Chen, Shin-Cheh;
Chen, Wenyan;
Jiang, Ou;
Wang, Jingfen;
Wu, Xinhong;
Wang, Xian;
Zang, Aimin;
Wang, Xiaojia;
Collins, Julie M.

Publication type:

Article

First-in-human phase I/Ib study of QL1706 (PSB205), a bifunctional PD1/CTLA4 dual blocker, in patients with advanced solid tumors.

Published in:

Journal of Hematology & Oncology, 2023, v. 16, n. 1, p. 1, doi. 10.1186/s13045-023-01445-1

By:

Zhao, Yuanyuan;
Ma, Yuxiang;
Zang, Aimin;
Cheng, Ying;
Zhang, Yiping;
Wang, Xiangcai;
Chen, Zhendong;
Qu, Song;
He, Jianbo;
Chen, Chuanben;
Jin, Chuan;
Zhu, Dongyuan;
Li, Qingshan;
Liu, Xianling;
Su, Wuyun;
Ba, Yi;
Hao, Yanrong;
Chen, Junmin;
Zhang, Guoping;
Qu, Shenhong

Publication type:

Article

Regorafenib monotherapy or combined with an immune-checkpoint inhibitor as later-line treatment for metastatic colorectal cancer: a multicenter, real-world retrospective study in China.

Published in:

BMC Cancer, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12885-023-11700-w

By:

Qu, Wang;
Liu, Zimin;
Chen, Xiaobing;
Liu, Bo;
Zhao, YunBo;
Yan, Hao;
Qu, Xiujuan;
Li, Shengmian;
Zang, Aimin;
Sun, Yongkun;
Zhu, Liangjun;
Zhou, Aiping

Publication type:

Article